Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia

Science

Volumn 297, Issue 5585, 2002, Pages 1333-1336

  Splawski, Igor ^a   Timothy, Katherine W ^a   Tateyama, Michihiro ^a   Clancy, Colleen E ^a   Malhotra, Alka ^a   Beggs, Alan H ^a   Cappuccio, Francesco P ^a   Sagnella, Giuseppe A ^a   Kass, Robert S ^a   Keating, Mark T ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; CELLS; DISEASES; HEALTH RISKS; SODIUM;

REPOLARIZATION;

CARDIOLOGY;

MOLECULAR MARKER;

CARDIOVASCULAR DISEASE; GENE;

ALLELISM; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEART ARRHYTHMIA; HEART REPOLARIZATION; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; NEGRO; PRIORITY JOURNAL; RACE; RISK ASSESSMENT; RISK FACTOR; SCN5A GENE; SODIUM TRANSPORT; UNITED STATES;

ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; ALLELES; AMINO ACID SEQUENCE; ARRHYTHMIA; CASE-CONTROL STUDIES; CELL LINE; CHILD; ELECTROCARDIOGRAPHY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ION CHANNEL GATING; LONG QT SYNDROME; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PATCH-CLAMP TECHNIQUES; PEDIGREE; POINT MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROBABILITY; RISK FACTORS; SODIUM CHANNELS; SYNCOPE; TRANSFECTION; VARIATION (GENETICS);

EID: 18544383162     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1073569     Document Type: Article

References (22)