Low hepatic lipase activity is a novel risk factor for coronary artery disease

Circulation

Volumn 104, Issue 25, 2001, Pages 3057-3062

  Dugi, Klaus A ^a,c   Brandauer, Karin ^a   Schmidt, Nikolaus ^a   Nau, Barbara ^a   Schneider, Jochen G ^a   Mentz, Stefani ^a   Keiper, Tanja ^a   Schaefer, Juergen R ^b   Meissner, Christoph ^a   Kather, Horst ^a   Bahner, Malte L ^a   Fiehn, Walter ^a   Kreuzer, Joerg ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c Department of Internal Medicine I ^*  (Germany)

Author keywords

Angiography; Atherosclerosis; Coronary disease; Lipoproteins

Indexed keywords

LIVER TRIACYLGLYCEROL LIPASE;

ADULT; ANGIOGRAPHY; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CORONARY ARTERY DISEASE; CORRELATION FUNCTION; DISEASE ASSOCIATION; ENZYME ACTIVITY; FAMILIAL HYPERCHOLESTEROLEMIA; HUMAN; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; PRIORITY JOURNAL; RISK FACTOR; SCORING SYSTEM;

EID: 0035909968     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc5001.100795     Document Type: Article

References (35)

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14. Hepatic lipase gene polymorphisms influence plasma HDL levels: Results from Finnish EARS participants: European Atherosclerosis Research Study
15. Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients
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17. The C-514T polymorphism in the human hepatic lipase gene promoter diminishes its activity
18. Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor
19. Functional characterization of 4 polymorphisms in promoter region of hepatic lipase gene
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