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Volumn 1, Issue 1, 2002, Pages 66-79

Pharmacogenetics of cardiovascular drugs

Author keywords

Drug metabolism; Drug response; Drug targets; Genetic polymorphisms; Pharmacogenetics; Pharmacogenomics

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; CARDIOVASCULAR AGENT; CYTOCHROME P450; GLYCOPROTEIN P;

EID: 0345924181     PISSN: 14739550     EISSN: 14774062     Source Type: Journal    
DOI: 10.1093/bfgp/1.1.66     Document Type: Article
Times cited : (10)

References (97)
  • 1
    • 0034660560 scopus 로고    scopus 로고
    • Pharmacogenetics and the practice of medicine
    • DOI 10.1038/35015728
    • Roses, A. D. (2000), 'Pharmacogenetics and the practice of medicine', Nature, Vol, 405, pp. 857-865. (Pubitemid 30407864)
    • (2000) Nature , vol.405 , Issue.6788 , pp. 857-865
    • Roses, A.D.1
  • 2
    • 0035775486 scopus 로고    scopus 로고
    • Pharmacogenomics: The inherited basis for interindividual differences in drug response
    • DOI 10.1146/annurev.genom.2.1.9
    • Evans, W. E. and Johnson, J. A. (2001), 'Pharmacogenomics: the inherited basis for inter-individual variability in drug response'. Ann. Rev. Genomics Hum. Genet., Vol. 2, pp. 9-39. (Pubitemid 35264999)
    • (2001) Annual Review of Genomics and Human Genetics , vol.2 , pp. 9-39
    • Evans, W.E.1    Johnson, J.A.2
  • 3
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans, W. E. and Relling, M. V. (1999), 'Pharmacogenomics: translating functional genomics into rational therapeutics', Science, Vol. 286, pp. 487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 4
    • 0033253481 scopus 로고    scopus 로고
    • HFSA guidelines for management of patients with heart failure caused by left ventricular systolic dysfunction - Pharmacological approaches
    • Heart Failure Society of America (HFSA) practice guidelines
    • Heart Failure Society of America (HFSA) practice guidelines (1999), 'HFSA guidelines for management of patients with heart failure caused by left ventricular systolic dysfunction - pharmacological approaches', J. Card. Fail., Vol. 5, pp. 357-382.
    • (1999) J. Card. Fail. , vol.5 , pp. 357-382
  • 5
    • 0028930346 scopus 로고
    • Department of Veterans Affairs single-drug therapy of hypertension study. Revised figures and new data
    • Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents
    • Materson, B.J., Reda, D.J. and Cushman, W. C. (1995), 'Department of Veterans Affairs single-drug therapy of hypertension study. Revised figures and new data. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents', Am. J. Hypertens., Vol. 8, pp. 189-192.
    • (1995) Am. J. Hypertens. , vol.8 , pp. 189-192
    • Materson, B.J.1    Reda, D.J.2    Cushman, W.C.3
  • 6
    • 0035799777 scopus 로고    scopus 로고
    • Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction
    • DOI 10.1056/NEJM200105033441802
    • Exner, D. V., Domanski, M.J. and Cohn, J. N. (2001), 'Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction', N. Engl. J. Med., Vol. 344, pp. 1351-1357. (Pubitemid 32378389)
    • (2001) New England Journal of Medicine , vol.344 , Issue.18 , pp. 1351-1357
    • Exner, D.V.1    Dries, D.L.2    Domanski, M.J.3    Cohn, J.N.4
  • 7
    • 0032836517 scopus 로고    scopus 로고
    • Racial differences in response to therapy for heart failure: Analysis of the Vasodilator-Heart Failure Trials
    • DOI 10.1016/S1071-9164(99)90001-5
    • Carson, P., Ziesche, S., Johnson, G. and Cohn, J. N. (1999), 'Racial differences in response to therapy for heart failure: analysis of the vasodilator-heart failure trials', J. Card. Fail., Vol. 5, pp. 178-187. (Pubitemid 29449255)
    • (1999) Journal of Cardiac Failure , vol.5 , Issue.3 , pp. 178-187
    • Carson, P.1    Ziesche, S.2    Johnson, G.3    Cohn, J.N.4
  • 8
    • 0033134676 scopus 로고    scopus 로고
    • Association between angiotensin-converting enzyme gene polymorphisms and regression of left ventricular hypertrophy in patients treated with angiotensin-converting enzyme inhibitors
    • DOI 10.1016/S0002-9343(99)00067-4, PII S0002934399000674
    • Kohno, M, Yokokawa, K., Minami, M. et al. (1999), 'Association between angiotensin-converting enzyme gene polymorphisms and regression of left ventricular hypertrophy in patients treated with angiotensin-converting enzyme inhibitors', Am. J. Med., Vol. 106, pp. 544-549. (Pubitemid 29231105)
    • (1999) American Journal of Medicine , vol.106 , Issue.5 , pp. 544-549
    • Kohno, M.1    Yokokawa, K.2    Minami, M.3    Kano, H.4    Yasunari, K.5    Hanehira, T.6    Yoshikawa, J.7
  • 9
    • 0025165779 scopus 로고
    • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
    • Rigat, B., Hubert, C, Alhenc-Gelas, F., Cambien, F., Corvol, P. and Soubrier, F. (1990), 'An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels', J. Clin. Invest., Vol. 86, pp. 1343-1346. (Pubitemid 20370444)
    • (1990) Journal of Clinical Investigation , vol.86 , Issue.4 , pp. 1343-1346
    • Rigat, B.1    Hubert, C.2    Alhenc-Gelas, F.3    Cambien, F.4    Corvol, P.5    Soubrier, F.6
  • 10
    • 0030474233 scopus 로고    scopus 로고
    • Relationship between the angiotensin converting enzyme gene polymorphism and the effects of enalapril on left ventricular hypertrophy and impaired diastolic filling in essential hypertension'. M- mode and pulsed Doppler echocardiographic studies
    • Sasaki, M., Oki, T., Iuchi, A. et al. (1996), 'Relationship between the angiotensin converting enzyme gene polymorphism and the effects of enalapril on left ventricular hypertrophy and impaired diastolic filling in essential hypertension'. M- mode and pulsed Doppler echocardiographic studies', J. Hypertens., Vol. 14, pp. 1403-1408.
    • (1996) J. Hypertens. , vol.14 , pp. 1403-1408
    • Sasaki, M.1    Oki, T.2    Iuchi, A.3
  • 11
    • 0030865823 scopus 로고    scopus 로고
    • Relationship between the response to the angiotensin converting enzyme inhibitor imidapril and the angiotensin converting enzyme genotype
    • Ohmichi, N., Iwai, N., Uchida, Y., Shichiri, G., Nakamura, Y. and Kinoshita, M (1997), 'Relationship between the response to the angiotensin converting enzyme inhibitor imidapril and the angiotensin converting enzyme genotype', Am. J. Hypertens., Vol. 10, pp. 951-955,
    • (1997) Am. J. Hypertens. , vol.10 , pp. 951-955
    • Ohmichi, N.1    Iwai, N.2    Uchida, Y.3    Shichiri, G.4    Nakamura, Y.5    Kinoshita, M.6
  • 12
    • 0034723042 scopus 로고    scopus 로고
    • Renin-angiotensin system gene polymorphisms: Potential mechanisms for their association with cardiovascular diseases
    • DOI 10.1016/S0014-2999(00)00823-2, PII S0014299900008232
    • Danser, A. H. and Schunkert, H. (2000), 'Renin-angiotensin system gene polymorphisms: potential mechanisms for their association with cardiovascular diseases', Eur. J. Pharmacol, Vol. 410, pp. 303-316. (Pubitemid 32008152)
    • (2000) European Journal of Pharmacology , vol.410 , Issue.2-3 , pp. 303-316
    • Danser, A.H.J.1    Schunkert, H.2
  • 16
    • 0032542030 scopus 로고    scopus 로고
    • Ace (I/D) genotype as a predictor of the magnitude and duration of the response to an ACE inhibitor drug (enalaprilat) in humans
    • Ueda, S., Meredith, P. A., Morton. J.J., Connell, J. M. and Elliott, H. L. (1998), 'ACE (I/D) genotype as a predictor of the magnitude and duration of the response to an ACE inhibitor drug (enalaprilat) in humans', Circulation, Vol. 98, pp. 2148-2153. (Pubitemid 28527474)
    • (1998) Circulation , vol.98 , Issue.20 , pp. 2148-2153
    • Ueda, S.1    Meredith, P.A.2    Morton, J.J.3    Connell, J.M.C.4    Elliott, H.L.5
  • 17
    • 0029012847 scopus 로고
    • Deletion-type allele of the angiotensin-converting enzyme gene is associated with progressive ventricular dilation after anterior myocardial infarction
    • Pinto, Y. M., van Gilst, W. H., Kingma, J. H. and Schunkert, H. (1995), 'Deletion-type allele of the angiotensin-converting enzyme gene is associated with progressive ventricular dilation after anterior myocardial infarction', J. Am. Coll. Cardiol., Vol. 25, pp. 1622-1626.
    • (1995) J. Am. Coll. Cardiol. , vol.25 , pp. 1622-1626
    • Pinto, Y.M.1    Van Gilst, W.H.2    Kingma, J.H.3    Schunkert, H.4
  • 18
    • 0030474233 scopus 로고    scopus 로고
    • Relationship between the angiotensin converting enzyme gene polymorphism and the effects of enalapril on left ventricular hypertrophy and impaired diastolic filling in essential hypertension: M-mode and pulsed Doppler echocardiographic studies
    • Sasaki, M, Oki, T., Iuchi, A. et al. (1996), 'Relationship between the angiotensin converting enzyme gene polymorphism and the effects of enalapril on left ventricular hypertrophy and impaired diastolic filling in essential hypertension: M-mode and pulsed Doppler echocardiographic studies', J. Hypertens., Vol. 14, pp. 1403-1408.
    • (1996) J. Hypertens. , vol.14 , pp. 1403-1408
    • Sasaki, M.1    Oki, T.2    Iuchi, A.3
  • 19
    • 0034604252 scopus 로고    scopus 로고
    • Insertion-deletion polymorphism of the ACE gene modulates reversibility of endothelial dysfunction with ACE inhibition
    • Prasad, A., Narayanan, S., Husain, S. et al. (2000), 'Insertion-deletion polymorphism of the ACE gene modulates reversibility of endothelial dysfunction with ACE inhibition', Circulation, Vol. 102, pp. 35-41. (Pubitemid 30430550)
    • (2000) Circulation , vol.102 , Issue.1 , pp. 35-41
    • Prasad, A.1    Narayanan, S.2    Husain, S.3    Padder, F.4    Waclawiw, M.5    Epstein, N.6    Quyyumi, A.A.7
  • 20
    • 0026669336 scopus 로고
    • Molecular basis of human hypertension: Role of angiotensinogen
    • Jeunemaitre, X., Soubrier, F., Kotelevtsev, Y. V. et al. (1992), 'Molecular basis of human hypertension: role of angiotensinogen', Cell, Vol. 71, pp. 169-180.
    • (1992) Cell , vol.71 , pp. 169-180
    • Jeunemaitre, X.1    Soubrier, F.2    Kotelevtsev, Y.V.3
  • 22
    • 0029586504 scopus 로고
    • Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition
    • Hingorani, A. D., Jia, H., Stevens, P. A., Hopper, R., Dickerson, J. E. and Brown, M.J. (1995), 'Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition', J. Hypertens., Vol. 13, pp. 1602-1609. (Pubitemid 26015783)
    • (1995) Journal of Hypertension , vol.13 , Issue.II12 , pp. 1602-1609
    • Hingorani, A.D.1    Jia, H.2    Stevens, P.A.3    Hopper, R.4    Dickerson, J.E.C.5    Brown, M.J.6
  • 23
    • 10544228945 scopus 로고    scopus 로고
    • Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of perindopril and nitrendipine on arterial stiffness in hypertensive individuals
    • Benetos, A., Cambien, F., Gautier, S. et al. (1996), 'Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of Perindopril and nitrendipine on arterial stiffness in hypertensive individuals'. Hypertension, Vol. 28, pp. 1081-1084. (Pubitemid 26415828)
    • (1996) Hypertension , vol.28 , Issue.6 , pp. 1081-1084
    • Benetos, A.1    Cambien, F.2    Gautier, S.3    Ricard, S.4    Safar, M.5    Laurent, S.6    Lacolley, P.7    Poirier, O.8    Topouchian, J.9    Asmar, R.10
  • 24
    • 0033406766 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor gene polymorphism predicts response to losartan and angiotensin II
    • DOI 10.1046/j.1523-1755.1999.00770.x
    • Miller, J. A., Thai, K. and Scholey, J. W. (1999), 'Angiotensin II type 1 receptor gene polymorphism predicts response to losartan and angiotensin II', Kidney Int., Vol. 56, pp. 2173-2180. (Pubitemid 30004746)
    • (1999) Kidney International , vol.56 , Issue.6 , pp. 2173-2180
    • Miller, J.A.1    Thai, K.2    Scholey, J.W.3
  • 25
    • 0001416627 scopus 로고    scopus 로고
    • Prediction ofblood pressure-response to ACE inhibitors by using patterns of genetic variation in the RAAS
    • Lithell, H., Berglund, L., Jonsson, J., Heutchel, K. and Jonsson, L. (1999), 'Prediction ofblood pressure-response to ACE inhibitors by using patterns of genetic variation in the RAAS', Circulation, Vol. 100, p. 1755.
    • (1999) Circulation , vol.100 , pp. 1755
    • Lithell, H.1    Berglund, L.2    Jonsson, J.3    Heutchel, K.4    Jonsson, L.5
  • 26
    • 0033858856 scopus 로고    scopus 로고
    • 2 receptor gene polymorphism is associated with angiotensin-converting enzyme inhibitor-related cough
    • Mukae, S., Aoki, S., Itoh, S., Iwata, T., Ueda, H. and Katagiri, T. (2000), 'Bradykinin B(2) receptor gene polymorphism is associated with angiotensin-converting enzyme inhibitor-related cough', Hypertension, Vol. 36, pp. 127-131. (Pubitemid 30602164)
    • (2000) Hypertension , vol.36 , Issue.1 , pp. 127-131
    • Mukae, S.1    Aoki, S.2    Itoh, S.3    Iwata, T.4    Ueda, H.5    Katagiri, T.6
  • 27
    • 0034942087 scopus 로고    scopus 로고
    • The ACE gene polymorphism and cough threshold for capsaicin after cilazapril usage
    • DOI 10.1053/rmed.2000.1005
    • Takahashi, T., Yamaguchi, E., Furuya, K. and Kawakami, Y. (2001), 'The ACE gene polymorphism and cough threshold for capsaicin after Cilazapril usage', Respir. Med., Vol. 95, pp. 130-135. (Pubitemid 32624444)
    • (2001) Respiratory Medicine , vol.95 , Issue.2 , pp. 130-135
    • Takahashi, T.1    Yamaguchi, E.2    Furuya, K.3    Kawakami, Y.4
  • 28
    • 0033550817 scopus 로고    scopus 로고
    • 2-adrenoceptor: Identification and rapid screening assay
    • Maqbool, A., Hall, A. S., Ball, S. G. and Balmforth, A.J. (1999), 'Common polymorphisms of beta 1-adrenoceptor: identification and rapid screening assay', Lancet, Vol. 353, p. 897. (Pubitemid 29126881)
    • (1999) Lancet , vol.353 , Issue.9156 , pp. 897
    • Maqbool, A.1    Hall, A.S.2    Ball, S.G.3    Balmforth, A.J.4
  • 29
    • 0034641736 scopus 로고    scopus 로고
    • Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness
    • Drysdale, C. M., McGraw, D. W., Stack, C. B. et al. (2000), 'Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness', Proc. Natl. Acad. Sci. USA, Vol. 97, pp. 10483-10488.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10483-10488
    • Drysdale, C.M.1    McGraw, D.W.2    Stack, C.B.3
  • 31
    • 0033617342 scopus 로고    scopus 로고
    • A gain-of-function polymorphism in a G-protein coupling domain of the human betal-adrenergic receptor
    • Mason, D. A., Moore, J. D., Green, S. A. and Liggett, S. B. (1999), 'A gain-of-function polymorphism in a G-protein coupling domain of the human betal-adrenergic receptor', J. Biol. Chem., Vol. 274, pp. 12670-12674.
    • (1999) J. Biol. Chem. , vol.274 , pp. 12670-12674
    • Mason, D.A.1    Moore, J.D.2    Green, S.A.3    Liggett, S.B.4
  • 33
    • 0035497742 scopus 로고    scopus 로고
    • Effects of beta 1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia
    • Humma, L. M., Puckett, B. J., Richardson, H. E. et al. (2001), 'Effects of beta 1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia', Am. J. Cardiol, Vol. 88, pp. 1034-1038.
    • (2001) Am. J. Cardiol , vol.88 , pp. 1034-1038
    • Humma, L.M.1    Puckett, B.J.2    Richardson, H.E.3
  • 39
    • 0033621973 scopus 로고    scopus 로고
    • 2-Adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals
    • Hoit, B. D., Suresh, D. P., Craft, L., Walsh, R. A. and Liggett, S. B. (2000), 'Beta 2-adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals', Am. Heart J., Vol. 139, pp. 537-542. (Pubitemid 30149205)
    • (2000) American Heart Journal , vol.139 , Issue.3 , pp. 537-542
    • Hoit, B.D.1    Suresh, D.P.2    Craft, L.3    Walsh, R.A.4    Liggett, S.B.5
  • 40
    • 0033822323 scopus 로고    scopus 로고
    • Beta(2)-adrenoceptor polymorphism determines vascular reactivity in humans
    • Cockcroft, J. R., Gazis, A. G., Cross, D.J. et al. (2000), 'Beta(2)-adrenoceptor polymorphism determines vascular reactivity in humans'. Hypertension, Vol. 36, pp. 371-375.
    • (2000) Hypertension , vol.36 , pp. 371-375
    • Cockcroft, J.R.1    Gazis, A.G.2    Cross, D.J.3
  • 41
    • 0033730995 scopus 로고    scopus 로고
    • A novel polymorphism in the gene coding for the beta(1)-adrenergic receptor associated with survival in patients with heart failure
    • Borjesson, M., Magnusson, Y., Hjalmarson, A. and Andersson, B. (2000), 'A novel polymorphism in the gene coding for the beta(1)-adrenergic receptor associated with survival in patients with heart failure', Eur. Heart J., Vol. 21, pp. 1853-1858.
    • (2000) Eur. Heart J. , vol.21 , pp. 1853-1858
    • Borjesson, M.1    Magnusson, Y.2    Hjalmarson, A.3    Andersson, B.4
  • 43
    • 0033821403 scopus 로고    scopus 로고
    • The gain-of-function G389R variant of the beta 1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects
    • O'Shaughnessy, K. M., Fu, B., Dickerson, C, Thurston, D. and Brown, M.J. (2000), 'The gain-of-function G389R variant of the beta 1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects', Clin. Sci. (Colch.), Vol. 99, pp. 233-238.
    • (2000) Clin. Sci. (Colch.) , vol.99 , pp. 233-238
    • O'Shaughnessy, K.M.1    Fu, B.2    Dickerson, C.3    Thurston, D.4    Brown, M.J.5
  • 45
    • 0035092564 scopus 로고    scopus 로고
    • 3-subunit and antihypertensive response to a thiazide diuretic
    • Turner, S. T., Schwartz, G. L., Chapman, A. B. and Boerwinkle, E. (2001), 'C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic', Hypertension, Vol. 37, pp. 739-743. (Pubitemid 32199059)
    • (2001) Hypertension , vol.37 , Issue.II2 , pp. 739-743
    • Turner, S.T.1    Schwartz, G.L.2    Chapman, A.B.3    Boerwinkle, E.4
  • 48
    • 0034724089 scopus 로고    scopus 로고
    • The apolipoprotein 4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction: A substudy of the Scandinavian Simvastatin Survival Study
    • Gerdes, L. U., Gerdes, C, Kervinen, K. et al. (2000), 'The apolipoprotein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction: a substudy of the Scandinavian simvastatin survival study', Circulation, Vol. 101, pp. 1366-1371. (Pubitemid 30169856)
    • (2000) Circulation , vol.101 , Issue.12 , pp. 1366-1371
    • Gerdes, L.U.1    Gerdes, C.2    Kervinen, K.3    Savolainen, M.4    Klausen, I.C.5    Hansen, P.S.6    Kesaniemi, Y.A.7    Faergeman, O.8
  • 49
    • 84945736658 scopus 로고
    • Apolipoprotein E and complement C3 polymorphism and their role in the response to gemfibrozil and low fat low cholesterol therapy
    • Nemeth, A., Szakmary, K., Kramer, J. et al. (1995), 'Apolipoprotein E and complement C3 polymorphism and their role in the response to gemfibrozil and low fat low cholesterol therapy', Eur. J. Clin. Client. Clin. Biochcm., Vol. 33, pp. 799-804.
    • (1995) Eur. J. Clin. Client. Clin. Biochcm. , vol.33 , pp. 799-804
    • Nemeth, A.1    Szakmary, K.2    Kramer, J.3
  • 50
    • 0028901424 scopus 로고
    • Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy
    • Ordovas, J. M., Lopez-Miranda, J., Perez-Jimenez, F. et al. (1995), 'Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy', Atherosclerosis, Vol. 113, pp. 157-166.
    • (1995) Atherosclerosis , vol.113 , pp. 157-166
    • Ordovas, J.M.1    Lopez-Miranda, J.2    Perez-Jimenez, F.3
  • 54
    • 0032127219 scopus 로고    scopus 로고
    • The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study
    • DOI 10.1016/S0021-9150(98)00053-7, PII S0021915098000537
    • Humphries, S. E., Luong, L. A., Talmud, P.J. et al. (1998), 'The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study', Atherosclerosis, Vol. 139, pp. 49-56. (Pubitemid 28341866)
    • (1998) Atherosclerosis , vol.139 , Issue.1 , pp. 49-56
    • Humphries, S.E.1    Luong, L.-A.2    Talmud, P.J.3    Frick, M.H.4    Antero Kesaniemi, Y.5    Pasternack, A.6    Taskinen, M.-R.7    Syvanne, M.8
  • 55
    • 0032993468 scopus 로고    scopus 로고
    • The type of mutation in the low density lipoprotein receptor gene influences the cholesterol-lowering response of the HMG-CoA reductase inhibitor simvastatin in patients with heterozygous familial hypercholesterolaemia
    • DOI 10.1016/S0021-9150(98)00274-3, PII S0021915098002743
    • Heath, K. E., Gudnason, V., Humphries, S. E. and Seed, M. (1999), 'The type of mutation in the low density lipoprotein receptor gene influences the cholesterol-lowering response of the HMG-CoA reductase inhibitor simvastatin in patients with heterozygous familial hypercholesterolaemia', Atherosclerosis, Vol. 143, pp. 41-54. (Pubitemid 29138702)
    • (1999) Atherosclerosis , vol.143 , Issue.1 , pp. 41-54
    • Heath, K.E.1    Gudnason, V.2    Humphries, S.E.3    Seed, M.4
  • 57
    • 0033957209 scopus 로고    scopus 로고
    • Interactions between angiotensin-I converting enzyme insertion/deletion polymorphism and response of plasma lipids and coronary atherosclerosis to treatment with fluvastatin: The lipoprotein and coronary atherosclerosis study
    • DOI 10.1016/S0735-1097(99)00535-5, PII S0735109799005355
    • Marian, A. J., Safavi, F., Ferlic, L., Dunn, J. K., Gotto, A. M. and Ballantyne, C. M. (2000), 'Interactions between angiotensin-I Converting enzyme insertion/deletion polymorphism and response of plasma lipids and coronary atherosclerosis to treatment with fluvastatin: the lipoprotein and coronary atherosclerosis study', J. Am. Coll. Cardiol, Vol. 35, pp. 89-95. (Pubitemid 30061265)
    • (2000) Journal of the American College of Cardiology , vol.35 , Issue.1 , pp. 89-95
    • Marian, A.J.1    Safavi, F.2    Ferlic, L.3    Dunn, J.K.4    Gotto, A.M.5    Ballantyne, C.M.6
  • 58
    • 0034066644 scopus 로고    scopus 로고
    • Lipid-lowering response of the HMG-CoA reductase inhibitor fluvastatin is influenced by polymorphisms in the low-density lipoprotein receptor gene in Brazilian patients with primary hypercholesterolemia
    • DOI 10.1002/(SICI)1098-2825(2000)14:3<125::AID-JCLA7>3.0.CO;2-S
    • Salazar, L. A., Hirata, M. H., Quintao, E. C. and Hirata, R. D. (2000), 'Lipid-lowering response of the HMG-CoA reductase inhibitor fluvastatin is influenced by polymorphisms in the low-density lipoprotein receptor gene in Brazilian patients with primary hypercholesterolemia', J. Clin. Lab. Anal., Vol. 14, pp. 125-131. (Pubitemid 30250114)
    • (2000) Journal of Clinical Laboratory Analysis , vol.14 , Issue.3 , pp. 125-131
    • Salazar Navarrete, L.A.1    Hirata, M.H.2    Quintao, E.C.R.3    Hirata, R.D.C.4
  • 59
    • 0032543748 scopus 로고    scopus 로고
    • High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives
    • DOI 10.1056/NEJM199806183382502
    • Martinelli, I., Sacchi, E., Landi, G., Taioli, E., Duca, F. and Mannucci, P. M. (1998), 'High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives', N. Engl. J. Med., Vol. 338, pp. 1793-1797. (Pubitemid 28277959)
    • (1998) New England Journal of Medicine , vol.338 , Issue.25 , pp. 1793-1797
    • Martinelli, I.1    Sacchi, E.2    Landi, G.3    Taioli, E.4    Duca, F.5    Mannucci, P.M.6
  • 61
    • 0029417137 scopus 로고
    • On the role of platelet Fc gamma Rlla phenotype in heparin-induced thrombocytopenia
    • Brandt, J. T., Isenhart, C. E., Osborne, J. M., Ahmed, A. and Anderson, C. L. (1995), 'On the role of platelet Fc gamma Rlla phenotype in heparin-induced thrombocytopenia', Thromb. Haemost., Vol. 74, pp. 1564-1572.
    • (1995) Thromb. Haemost. , vol.74 , pp. 1564-1572
    • Brandt, J.T.1    Isenhart, C.E.2    Osborne, J.M.3    Ahmed, A.4    Anderson, C.L.5
  • 64
    • 0035852892 scopus 로고    scopus 로고
    • Platelet glycoprotein IIIa pl(a) polymorphism and effects of aspirin on thrombin generation
    • Szczeklik, A., Sanak, M. and Undas, A. (2001), 'Platelet glycoprotein IIIa pl(a) polymorphism and effects of aspirin on thrombin generation', Circulation, Vol. 103, pp. E33-34.
    • (2001) Circulation , vol.103
    • Szczeklik, A.1    Sanak, M.2    Undas, A.3
  • 65
    • 0033761053 scopus 로고    scopus 로고
    • Relationship between bleeding time, aspirin and the P1A1/ A2 polymorphism of platelet glycoprotein IIIa
    • Szczeklik, A., Undas, A., Sanak, M., Frolow, M. and Wegrzyn, W. (2000), 'Relationship between bleeding time, aspirin and the P1A1/ A2 polymorphism of platelet glycoprotein IIIa', Br. J. Haematol., Vol. 110, pp. 965-967.
    • (2000) Br. J. Haematol. , vol.110 , pp. 965-967
    • Szczeklik, A.1    Undas, A.2    Sanak, M.3    Frolow, M.4    Wegrzyn, W.5
  • 68
    • 0034028029 scopus 로고    scopus 로고
    • Cardiac K+ channels and drug-acquired long QT syndrome
    • Drici, M. D. and Barhanin, J. (2000), 'Cardiac K+ channels and drug-acquired long QT syndrome', Therapie, Vol. 55, pp. 185-193. (Pubitemid 30319280)
    • (2000) Therapie , vol.55 , Issue.1 , pp. 185-193
    • Drici, M.-D.1    Barhanin, J.2
  • 69
    • 0033574273 scopus 로고    scopus 로고
    • MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
    • Abbott, G. W., Sesti, F., Splawski, I. et al. (1999), 'MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia', Cell, Vol. 97, pp. 175-187.
    • (1999) Cell , vol.97 , pp. 175-187
    • Abbott, G.W.1    Sesti, F.2    Splawski, I.3
  • 70
    • 0034723046 scopus 로고    scopus 로고
    • Pharmacogenetics of cardiac K(+) channels
    • Escande, D. (2000), 'Pharmacogenetics of cardiac K(+) channels', Eur. J. Pharmacol., Vol 410, pp. 281-287.
    • (2000) Eur. J. Pharmacol. , vol.410 , pp. 281-287
    • Escande, D.1
  • 71
    • 0035040834 scopus 로고    scopus 로고
    • Pharmacogenetics and drug-induced arrhythmias
    • DOI 10.1016/S0008-6363(00)00302-3, PII S0008636300003023
    • Roden, D. M. (2001), 'Pharmacogenetics and drug-induced arrhythmias', Cardiovasc. Res., Vol. 50, pp. 224-231. (Pubitemid 32382149)
    • (2001) Cardiovascular Research , vol.50 , Issue.2 , pp. 224-231
    • Roden, D.M.1
  • 72
    • 0001416627 scopus 로고    scopus 로고
    • Prediction of blood pressure response to ACE inhibitors by using patterns of genetic variation in the RAAS
    • Lithell, H., Berglund, L., Jonsson, J. and Jonsson, L. (1999), 'Prediction of blood pressure response to ACE inhibitors by using patterns of genetic variation in the RAAS', Circulation, Vol. 100, pp. 1755.
    • (1999) Circulation , vol.100 , pp. 1755
    • Lithell, H.1    Berglund, L.2    Jonsson, J.3    Jonsson, L.4
  • 76
    • 0032565878 scopus 로고    scopus 로고
    • Nicotine metabolism defect reduces smoking [8]
    • DOI 10.1038/31623
    • Pianezza, M. L., Sellers, E. M. and Tyndale, R. F. (1998), 'Nicotine metabolism defect reduces smoking', Nature, Vol. 393, p. 750. (Pubitemid 28299478)
    • (1998) Nature , vol.393 , Issue.6687 , pp. 750
    • Pianezza, M.L.1    Sellers, E.M.2    Tyndale, R.F.3
  • 77
    • 0030711683 scopus 로고    scopus 로고
    • Cigarette smoking, cardiovascular disease, and stroke: A statement for healthcare professionals from the American Heart Association
    • Ockene, I. S. and Miller, N. H. (1997), 'Cigarette smoking, cardiovascular disease, and stroke: a statement for healthcare professionals from the American Heart Association', Circulation, Vol. 96, pp. 3243-3247. (Pubitemid 27500133)
    • (1997) Circulation , vol.96 , Issue.9 , pp. 3243-3247
    • Ockene, I.S.1    Miller, N.H.2
  • 78
    • 0029798351 scopus 로고    scopus 로고
    • Genetic analysis of the human cytochrome P450 CYP2C9 locus
    • DOI 10.1097/00008571-199610000-00007
    • Stubbins, M. J., Harries, L. W., Smith, G., Tarbit, M. H. and Wolf, C. R. (1996), 'Genetic analysis of the human cytochrome P450 CYP2C9 locus', Pharmacogenetics, Vol. 6, pp. 429-439. (Pubitemid 26380099)
    • (1996) Pharmacogenetics , vol.6 , Issue.5 , pp. 429-439
    • Stubbins, M.J.1    Harries, L.W.2    Smith, G.3    Tarbit, M.H.4    Wolf, C.R.5
  • 79
    • 0035128503 scopus 로고    scopus 로고
    • Oral anticoagulants: Mechanism of action, clinical effectiveness, and optimal therapeutic range
    • Hirsh J., Dalen, J., Anderson, D. R. et al. (2001), 'Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range', Chest, Vol. 119(1 Suppl), pp. 8S-21S. (Pubitemid 32154192)
    • (2001) Chest , vol.119 , Issue.SUPPL. 1
    • Hirsh, J.1    Dalen, J.E.2    Anderson, D.R.3    Poller, L.4    Bussey, H.5    Ansell, J.6    Deykin, D.7
  • 80
    • 0034283762 scopus 로고    scopus 로고
    • Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment
    • Taube, J., Halsall, D. and Baglin, T. (2000), 'Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment', Blood, Vol. 96, pp. 1816-1819. (Pubitemid 30661066)
    • (2000) Blood , vol.96 , Issue.5 , pp. 1816-1819
    • Taube, J.1    Halsall, D.2    Baglin, T.3
  • 81
    • 0033884635 scopus 로고    scopus 로고
    • Cytochrome P450 polymorphisms are associated with reduced warfarin dose
    • DOI 10.1067/msy.2000.107283
    • Freeman, B. D., Zehnbauer, B. A., McGrath, S., Borecki, I. and Buchman, T. G. (2000), 'Cytochrome P450 polymorphisms are associated with reduced warfarin dose', Surgery, Vol. 128, pp. 281-285. (Pubitemid 30623510)
    • (2000) Surgery , vol.128 , Issue.2 , pp. 281-285
    • Freeman, B.D.1    Zehnbauer, B.A.2    McGrath, S.3    Borecki, I.4    Buchman, T.G.5
  • 83
    • 0033608466 scopus 로고    scopus 로고
    • Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
    • DOI 10.1016/S0140-6736(98)04474-2
    • Aithal, G. P., Day, C. P., Kesteven, P.J. and Daly, A. K. (1999), 'Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications', Lancet, Vol. 353, pp. 717-719. (Pubitemid 29103806)
    • (1999) Lancet , vol.353 , Issue.9154 , pp. 717-719
    • Aithal, G.P.1    Day, C.P.2    Kesteven, P.J.L.3    Daly, A.K.4
  • 84
    • 0030860004 scopus 로고    scopus 로고
    • Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution
    • DOI 10.1097/00008571-199706000-00004
    • Marez, D., Legrand, M., Sabbagh, N. et al. (1997), 'Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution', Pharmacogenetics, Vol. 7, pp. 193-202. (Pubitemid 27290633)
    • (1997) Pharmacogenetics , vol.7 , Issue.3 , pp. 193-202
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Lo Guidice, J.-M.4    Spire, C.5    Lafitte, J.-J.6    Meyer, U.A.7    Broly, F.8
  • 85
    • 0020409410 scopus 로고
    • Oxidation phenotype. A major determinant of metoprolol metabolism and response
    • Lennard, M. S., Silas, J. H., Freestone, S., Ramsay, L. E., Tucker, G. T. and Woods, H. F. (1982), 'Oxidation phenotype - a major determinant of metoprolol metabolism and response', N. Engl. J. Med., Vol. 307, pp. 1558-1560. (Pubitemid 13245431)
    • (1982) New England Journal of Medicine , vol.307 , Issue.25 , pp. 1558-1560
    • Lennard, M.S.1    Silas, J.H.2    Freestone, S.3
  • 86
    • 0021082394 scopus 로고
    • Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers
    • Lennard, M. S., Tucker, G. T., Silas, J. H., Freestone, S., Ramsay, L. E. and Woods, H. F. (1983), 'Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers', Clin. Pharmacol. Ther., Vol. 34, pp. 732-737. (Pubitemid 14219918)
    • (1983) Clinical Pharmacology and Therapeutics , vol.34 , Issue.6 , pp. 732-737
    • Lennard, M.S.1    Tucker, G.T.2    Silas, J.H.3
  • 89
    • 0029919063 scopus 로고    scopus 로고
    • Metoprolol metabolism via cytochrome P4502D6 in ethnic populations
    • Johnson, J. A. and Burlew, B. S. (1996), 'Metoprolol metabolism via cytochrome P4502D6 in ethnic populations', Drug Metab. Dispos., Vol. 24, pp. 350-355. (Pubitemid 26087089)
    • (1996) Drug Metabolism and Disposition , vol.24 , Issue.3 , pp. 350-355
    • Johnson, J.A.1    Burlew, B.S.2
  • 90
  • 92
    • 0035052559 scopus 로고    scopus 로고
    • Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms
    • DOI 10.1097/00008571-200104000-00004
    • Fretland, A. J., Leff, M. A., Doll, M. A. and Hein, D. W. (2001), 'Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms', Pharmacogenetics, Vol. 11, pp. 207-215. (Pubitemid 32319870)
    • (2001) Pharmacogenetics , vol.11 , Issue.3 , pp. 207-215
    • Fretland, A.J.1    Leff, M.A.2    Doll, M.A.3    Hein, D.W.4
  • 93
    • 0021813284 scopus 로고
    • N-acetylation pharmacogenetics
    • Weber, W. W. and Hein, D. W. (1985), 'N-acetylation pharmacogenetics', Pharmacol. Rev., Vol. 37, pp. 25-79. (Pubitemid 15081093)
    • (1985) Pharmacological Reviews , vol.37 , Issue.1 , pp. 25-79
    • Weber, W.W.1    Hein, D.W.2
  • 94
    • 0020060663 scopus 로고
    • Hydralazine, antinuclear antibodies, and the lupus syndrome
    • Mansilla-Tinoco, R., Harland, S. J., Ryan, P.J. et al. (1982), 'Hydralazine, antinuclear antibodies, and the lupus syndrome', Br. Med. J., Vol. 284, pp. 936-939. (Pubitemid 12192944)
    • (1982) British Medical Journal , vol.284 , Issue.6320 , pp. 936-939
    • Mansilla Tinoco, R.1    Harland, S.J.2    Ryan, P.3
  • 95
    • 0018099670 scopus 로고
    • Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome
    • Woosley, R. L., Drayer, D. E., Reidenberg, M. M., Nies, A. S, Carr, K. and Oates, J. A. (1978), 'Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome', N. Engl. J. Med., Vol. 298, pp. 1157-1159. (Pubitemid 8356479)
    • (1978) New England Journal of Medicine , vol.298 , Issue.21 , pp. 1157-1159
    • Woosley, R.L.1    Drayer, D.E.2    Reidenberg, M.M.3


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