Synthesis and evaluation of δ-lactams (piperazones) as elastase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 3, 2003, Pages 387-389

  Seibel, Jürgen ^a   Brown, David ^b   Amour, Augustin ^b   Macdonald, Simon J ^b   Oldham, Neil J ^a   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 PIPERIDONE DERIVATIVE; ELASTASE; ELASTASE INHIBITOR; LEUKOCYTE ELASTASE; PIPERAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; NONHUMAN; SWINE;

ANIMALS; CYCLIZATION; HUMANS; INDICATORS AND REAGENTS; KINETICS; LACTAMS; MAGNETIC RESONANCE SPECTROSCOPY; PANCREATIC ELASTASE; SERINE PROTEINASE INHIBITORS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWINE;

SUIDAE;

EID: 0037325675     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00995-2     Document Type: Article

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