Reversible acylation of elastase by γ-lactam analogues of β-lactam inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 23, 1997, Pages 2973-2978

  Westwood, Nicholas J ^a   Claridge, Timothy D W ^a   Edwards, Philip N ^b   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM DERIVATIVE; ELASTASE; ELASTASE INHIBITOR; GAMMA LACTAM DERIVATIVE; PANCREATIC ELASTASE;

ACYLATION; ARTICLE; COMPLEX FORMATION; ENZYME BINDING; ENZYME MODIFICATION; IN VITRO STUDY; MASS SPECTROMETRY; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; SWINE; THERMODYNAMICS;

EID: 0030687685     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10123-8     Document Type: Article

References (30)

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