Mechanistic insights into the inhibition of serine proteases by monocyclic lactams

Biochemistry

Volumn 38, Issue 25, 1999, Pages 7989-7998

  Wilmouth, Rupert C ^a   Kassamally, Samia ^a   Westwood, Nicholas J ^a   Sheppard, Robert J ^a   Claridge, Timothy D W ^a   Aplin, Robin T ^a   Wright, Penny A ^a   Pritchard, Gareth J ^a   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM; BETA LACTAM ANTIBIOTIC; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR;

ARTICLE; CRYSTAL STRUCTURE; ENZYME INHIBITION; HYDROLYSIS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; KINETICS; LACTAMS; MASS SPECTROMETRY; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PANCREATIC ELASTASE; SERINE PROTEINASE INHIBITORS; SWINE;

SUIDAE;

EID: 0033594922     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990098y     Document Type: Article

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