메뉴 건너뛰기




Volumn 7, Issue 2, 2003, Pages 148-152

Gene therapy for asthma

Author keywords

Airway epithelium; Asthma; Gene therapy; IFN ; IL 12,; Th1; Th2; 2 adrenergic receptor

Indexed keywords

ANTIASTHMATIC AGENT; ANTISENSE OLIGONUCLEOTIDE; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; GAMMA INTERFERON; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 9; LYMPHOTOXIN; MAJOR BASIC PROTEIN; STAT4 PROTEIN; STAT6 PROTEIN; STEROID; TUMOR NECROSIS FACTOR ALPHA; VIRUS PROTEIN;

EID: 0037302973     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1525-0016(03)00003-0     Document Type: Short Survey
Times cited : (45)

References (35)
  • 1
    • 0033604656 scopus 로고    scopus 로고
    • Induction and regulation of the IgE response
    • Corry, D. B., and Kheradmand, F. (1999). Induction and regulation of the IgE response. Nature 402: 1318-23.
    • (1999) Nature , vol.402 , pp. 1318-1323
    • Corry, D.B.1    Kheradmand, F.2
  • 2
    • 0031952393 scopus 로고    scopus 로고
    • Mucosal IL-12 gene delivery inhibits allergic airways disease and restores local antiviral immunity
    • Hogan, S. P., Foster, P. S., Tan, X., and Ramsay, A. J. (1998). Mucosal IL-12 gene delivery inhibits allergic airways disease and restores local antiviral immunity. Eur. J. Immunol. 28: 413-423.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 413-423
    • Hogan, S.P.1    Foster, P.S.2    Tan, X.3    Ramsay, A.J.4
  • 3
    • 0035680992 scopus 로고    scopus 로고
    • Construction of single-chain interleukin-12 DNA plasmid to treat airway hyperresponsiveness in an animal model of asthma
    • Lee, Y. L., et al. (2001). Construction of single-chain interleukin-12 DNA plasmid to treat airway hyperresponsiveness in an animal model of asthma. Hum. Gene Ther 12: 2065-2079.
    • (2001) Hum. Gene Ther , vol.12 , pp. 2065-2079
    • Lee, Y.L.1
  • 4
    • 0033194627 scopus 로고    scopus 로고
    • Regulation of allergic mucosal sensitization by interleukin-12 gene transfer to the airway
    • Stampfli, M. R., et al. (1999). Regulation of allergic mucosal sensitization by interleukin-12 gene transfer to the airway. Am. J. Respir. Cell Mol. Biol. 21: 317-326.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.21 , pp. 317-326
    • Stampfli, M.R.1
  • 5
    • 0036723946 scopus 로고    scopus 로고
    • Gene therapy with galectin-3 inhibits bronchial obstruction and inflammation in antigen-challenged rats through interleukin-5 gene downregulation
    • del Pozo, V., et al. (2002). Gene therapy with galectin-3 inhibits bronchial obstruction and inflammation in antigen-challenged rats through interleukin-5 gene downregulation. Am. J. Respir. Crit. Care Med. 166: 732-737.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , pp. 732-737
    • del Pozo, V.1
  • 6
    • 6644223789 scopus 로고    scopus 로고
    • Effects of recombinant human interleukin-12 one eosinophils, airway hyper-responsiveness, and the late asthmatic response
    • Bryan, S. A., et al. (2000). Effects of recombinant human interleukin-12 one eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356: 2149-2153.
    • (2000) Lancet , vol.356 , pp. 2149-2153
    • Bryan, S.A.1
  • 7
    • 0035105111 scopus 로고    scopus 로고
    • Elemental signals regulating eosinophil accumulation in the lung
    • Foster, P. S., et al. (2001). Elemental signals regulating eosinophil accumulation in the lung. Immunol. Rev. 179: 173-181.
    • (2001) Immunol. Rev. , vol.179 , pp. 173-181
    • Foster, P.S.1
  • 8
    • 0036401603 scopus 로고    scopus 로고
    • Adenovirus-mediated interferon gamma gene therapy for allergic asthma: Involvement of interleukin 12 and STAT4 signaling
    • Behera, A. K., Kumar, M., Lockey, R. F., and Mohapatra, S. S. (2002). Adenovirus-mediated interferon gamma gene therapy for allergic asthma: involvement of interleukin 12 and STAT4 signaling. Hum. Gene Ther. 13: 1697-1709.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 1697-1709
    • Behera, A.K.1    Kumar, M.2    Lockey, R.F.3    Mohapatra, S.S.4
  • 9
    • 0030587861 scopus 로고    scopus 로고
    • Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice
    • Li, X. M., et al. (1996). Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice. J. Immunol. 157: 3216-3219.
    • (1996) J. Immunol. , vol.157 , pp. 3216-3219
    • Li, X.M.1
  • 10
    • 0033543072 scopus 로고    scopus 로고
    • Systemic and local interferon gamma gene delivery to the lungs for treatment of allergen-induced airway hyperresponsiveness in mice
    • Dow, S. W., Schwarze, J., Heath, T. D., Potter, T. A., and Gelfand, E. W. (1999). Systemic and local interferon gamma gene delivery to the lungs for treatment of allergen-induced airway hyperresponsiveness in mice. Hum. Gene Ther. 10: 1905-1914.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1905-1914
    • Dow, S.W.1    Schwarze, J.2    Heath, T.D.3    Potter, T.A.4    Gelfand, E.W.5
  • 11
    • 0035873683 scopus 로고    scopus 로고
    • II-18 gene transfer by adenovirus prevents the development of and reverses established allergen-induced airway hyperreactivity
    • Walter, D. M., et al. (2001). II-18 gene transfer by adenovirus prevents the development of and reverses established allergen-induced airway hyperreactivity. J. Immunol. 166: 6392-6398.
    • (2001) J. Immunol. , vol.166 , pp. 6392-6398
    • Walter, D.M.1
  • 12
    • 0012690145 scopus 로고    scopus 로고
    • Treatment of experimental asthma by long-term gene therapy directed against IL-4 and IL-13
    • pages
    • Zavorotinskaya, T., Tomkinson, A., and Murphy, J. E. (2003). Treatment of experimental asthma by long-term gene therapy directed against IL-4 and IL-13. Journal vol: pages.
    • (2003) Journal
    • Zavorotinskaya, T.1    Tomkinson, A.2    Murphy, J.E.3
  • 13
    • 0035340763 scopus 로고    scopus 로고
    • A murine receptor antagonist that inhibits IL-4 and IL-13 -induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness
    • Tomkinson, A., et al. (2001). A murine receptor antagonist that inhibits IL-4 and IL-13 -induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness. J. Immunol. 166: 5792-5800.
    • (2001) J. Immunol. , vol.166 , pp. 5792-5800
    • Tomkinson, A.1
  • 14
    • 0031723763 scopus 로고    scopus 로고
    • Expression of the IL-4 receptor alpha-subunit is increased in bronchial biopsy specimens from atopic and nonatopic asthmatic subjects
    • Kotsimbos, T. C., et al. (1998). Expression of the IL-4 receptor alpha-subunit is increased in bronchial biopsy specimens from atopic and nonatopic asthmatic subjects. J. Allergy Clin. Immunol. 102: 859-866.
    • (1998) J. Allergy Clin. Immunol. , vol.102 , pp. 859-866
    • Kotsimbos, T.C.1
  • 15
    • 0036736840 scopus 로고    scopus 로고
    • CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation
    • Oh, J. W., et al. (2002). CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. J. Allergy Clin. Immunol. 110: 460-468.
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 460-468
    • Oh, J.W.1
  • 16
    • 0033219725 scopus 로고    scopus 로고
    • Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice
    • Stampfli, M. R., et al. (1999). Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice. Am. J. Respir. Cell Mol. Biol. 21: 586-596.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.21 , pp. 586-596
    • Stampfli, M.R.1
  • 17
    • 12944267034 scopus 로고    scopus 로고
    • IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization
    • Makela, M. J., et al. (2000). IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization. Proc. Natl. Acad. Sci. USA 97: 6007-6012.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6007-6012
    • Makela, M.J.1
  • 19
    • 0036912223 scopus 로고    scopus 로고
    • CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma
    • Jain, V. V., et al. (2002). CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma. J. Allergy Clin. Immunol. 110: 867-872.
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 867-872
    • Jain, V.V.1
  • 20
    • 0036844343 scopus 로고    scopus 로고
    • Immunomodulatory effects of CpG oligodeoxynucleotides on established th2 responses
    • Kitagaki, K., Jain, V. V., Businga, T. R., Hussain, I., and Kline, J. N. (2002). Immunomodulatory effects of CpG oligodeoxynucleotides on established th2 responses. Clin. Diagn. Lab Immunol. 9: 1260-1269.
    • (2002) Clin. Diagn. Lab. Immunol. , vol.9 , pp. 1260-1269
    • Kitagaki, K.1    Jain, V.V.2    Businga, T.R.3    Hussain, I.4    Kline, J.N.5
  • 21
    • 0032534602 scopus 로고    scopus 로고
    • Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
    • Broide, D., et al. (1998). Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J. Immunol. 161: 7054-7062.
    • (1998) J. Immunol. , vol.161 , pp. 7054-7062
    • Broide, D.1
  • 22
    • 0037059509 scopus 로고    scopus 로고
    • Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
    • Finotto, S., et al. (2002). Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 295: 336-338.
    • (2002) Science , vol.295 , pp. 336-338
    • Finotto, S.1
  • 23
    • 0033987397 scopus 로고    scopus 로고
    • CD4(+) T helper cells engineered to produce latent TGF-betal reverse allergen-induced airway hyperreactivity and inflammation
    • Hansen, G., et al. (2000). CD4(+) T helper cells engineered to produce latent TGF-betal reverse allergen-induced airway hyperreactivity and inflammation. J. Clin. Invest. 105: 61-70.
    • (2000) J. Clin. Invest. , vol.105 , pp. 61-70
    • Hansen, G.1
  • 24
    • 0034789737 scopus 로고    scopus 로고
    • Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance
    • McGraw, D. W., et al. (2001). Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance. Am. J. PhysioL Lung Cell Mol. Physiol. 281: L895-903.
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.281
    • McGraw, D.W.1
  • 25
    • 0035943605 scopus 로고    scopus 로고
    • Modification of the beta 2-adrenergic receptor to engineer a receptor-effector complex for gene therapy
    • Small, K. M., Brown, K. M., Forbes, S. L., and Liggett, S. B. (2001). Modification of the beta 2-adrenergic receptor to engineer a receptor-effector complex for gene therapy. J. Biol. Chem. 276: 31596-31601.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31596-31601
    • Small, K.M.1    Brown, K.M.2    Forbes, S.L.3    Liggett, S.B.4
  • 27
    • 0031025249 scopus 로고    scopus 로고
    • DNA antisense therapy for asthma in an animal model
    • Nyce, J. W., and Metzger, W. J. (1997). DNA antisense therapy for asthma in an animal model. Nature 385: 721-725.
    • (1997) Nature , vol.385 , pp. 721-725
    • Nyce, J.W.1    Metzger, W.J.2
  • 28
    • 0035942265 scopus 로고    scopus 로고
    • Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma
    • Nakanishi, A., et al. (2001). Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma. Proc. Natl. Acad. Sci. USA 98: 5175-5180.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5175-5180
    • Nakanishi, A.1
  • 29
    • 0033060042 scopus 로고    scopus 로고
    • The glucocorticoid receptor gene as a candidate for gene therapy in asthma
    • Mathieu, M., et al. (1999). The glucocorticoid receptor gene as a candidate for gene therapy in asthma. Gene Ther. 6: 245-252.
    • (1999) Gene Ther. , vol.6 , pp. 245-252
    • Mathieu, M.1
  • 30
    • 17944404406 scopus 로고    scopus 로고
    • Airway epithelium: More than just a barrier!
    • Folkerts, G., and Nijkamp, F. P. (1998). Airway epithelium: more than just a barrier! Trends Pharmacol. Sci. 19: 334-341.
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 334-341
    • Folkerts, G.1    Nijkamp, F.P.2
  • 31
    • 0033537837 scopus 로고    scopus 로고
    • Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia
    • Walters, R. W., et al. (1999). Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia. J. Biol. Chem. 274: 10219-10226.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10219-10226
    • Walters, R.W.1
  • 32
    • 0035984565 scopus 로고    scopus 로고
    • Thixotropic solutions enhance viral-mediated gene transfer to airway epithelia
    • Seiler, M. P., et al. (2002). Thixotropic solutions enhance viral-mediated gene transfer to airway epithelia. Am. J. Respir. Cell Mol. Biol. 27: 133-140.
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.27 , pp. 133-140
    • Seiler, M.P.1
  • 33
    • 0032128197 scopus 로고    scopus 로고
    • Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo
    • Fasbender, A., et al. (1998). Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo. J. Clin. Invest. 102: 184-193.
    • (1998) J. Clin. Invest. , vol.102 , pp. 184-193
    • Fasbender, A.1
  • 34
    • 0037222237 scopus 로고    scopus 로고
    • Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo
    • pages
    • Gregory, L. G., et al. (2003). Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo. Mol. Ther. 7: pages.
    • (2003) Mol. Ther. , vol.7
    • Gregory, L.G.1
  • 35
    • 0037083946 scopus 로고    scopus 로고
    • Acute hyperoxic lung injury does not impede adenoviral-mediated alveolar gene transfer
    • Factor, P., Mendez, M., Mutlu, G. M., and Dumasius, V. (2002). Acute hyperoxic lung injury does not impede adenoviral-mediated alveolar gene transfer. Am. J. Respir. Crit. Care Med. 165: 521-526.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , pp. 521-526
    • Factor, P.1    Mendez, M.2    Mutlu, G.M.3    Dumasius, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.