Non-classical pathways of cell-mediated allograft rejection: New challenges for tolerance induction?

American Journal of Transplantation

Volumn 3, Issue 2, 2003, Pages 101-106

  Le Moine, Alain ^a   Goldman, Michel ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

CD8+ T cells; Co stimulation blockade; Pathway of rejection pathways; Th2

Indexed keywords

CYTOKINE; FAS LIGAND; INTERLEUKIN 2;

ALLOGRAFT; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; GRAFT REJECTION; HEART TRANSPLANTATION; HUMAN; IMMUNOLOGICAL TOLERANCE; NATURAL KILLER CELL; NONHUMAN; SHORT SURVEY; T LYMPHOCYTE SUBPOPULATION; TH2 CELL;

ANIMALS; ANTIGENS; ANTIGENS, SURFACE; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; FAS LIGAND PROTEIN; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; IMMUNITY, CELLULAR; INTERLEUKIN-2; KIDNEY TRANSPLANTATION; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; MICE; PROTEINS; SKIN TRANSPLANTATION; TH2 CELLS; TRANSPLANTATION TOLERANCE;

EID: 0037297039     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-6143.2002.00026.x     Document Type: Short Survey

References (62)

1. Le Moine A, Goldman M, Abramowicz D. Multiple pathways to allograft rejection. Transplantation 2002; 9: 1373-1381.
2. + T cells. J Immunol 1998; 10: 5236-5244.
3. Le Moine A, Surquin M, Demoor FX et al. IL-5 mediates eosinophilic rejection of MHC class II-disparate skin allografts in mice. J Immunol 1999; 7: 3778-3784.
4. + T cells or B cells. J Immunol 1998; 4: 1868-1874.
5. VanBuskirk AM, Wakely ME, Orosz CG. Transfusion of polarized TH2-like cell populations into SCID mouse cardiac allograft recipients results in acute allograft rejection. Transplantation 1996; 2: 229-238.
6. Zhang Y, Apilado R, Coleman J et al. Interferon gamma stabilizes the T helper cell type 1 phenotype. J Exp Med 2001; 2: 165-172.
7. Das G, Sheridan S, Janeway CA, Jr. The source of early IFN-gamma that plays a role in Th1 priming. J Immunol 2001; 4: 2004-2010.
8. Foucras G, Coudert JD, Coureau C, Guery JC. Dendritic cells prime in vivo alloreactive CD4 T lymphocytes toward type 2 cytokine- and TGF-beta-producing cells in the absence of CD8 T cell activation. J Immunol 2000; 9: 4994-5003.
9. Braun MY, Desalle F, Le Moine A et al. IL-5 and eosinophils mediate the rejection of fully histoincompatible vascularized cardiac allografts: regulatory role of alloreactive CD8 (+) T lymphocytes and IFN-gamma. Eur J Immunol 2000; 5: 1290-1296.
10. + T cells results in Th2 cytokine production and alternate mechanisms of allograft rejection. Transplantation 1995; 8: 1155-1161.
11. Thomas MJ, Noble A, Sawicka E, Askenase PW, Kemeny DM. CD8 T cells inhibit IgE via dendritic cell IL-12 induction that promotes Th1 T cell counter-regulation. J Immunol 2002;70:216-223.
12. Ensminger SM, Spriewald BM, Sorensen HV et al. Critical role for IL-4 in the development of transplant arteriosclerosis in the absence of CD40-CD154 costimulation. J Immunol 2001; 1: 532-541.
13. 2-microglobulin as a minor transplantation antigen involves multiple effector pathways: role of Fas-Fas ligand interactions and Th2-dependent graft eosinophil infiltrates. J Immunol 2002; 1: 500-506.
14. Foster PF, Sankary HN, Hart M, Ashmann M, Williams JW. Blood and graft eosinophilia as predictors of rejection in human liver transplantation. Transplantation 1989; 1: 72-74.
15. Foster PF, Bhattacharyya A, Sankary HN, Coleman J, Ashmann M, Williams JW. Eosinophil cationic protein's role in human hepatic allograft rejection. Hepatology 1991; 6: 1117-1125.
16. de Groen PC, Kephart GM, Gleich GJ, Ludwig J. The eosinophil as an effector cell of the immune response during hepatic allograft rejection. Hepatology 1994; 3: 654-662.
17. Martinez OM, Villanueva JC, Lake J, Roberts JP, Ascher NL, Krams SM. IL-2 and IL-5 gene expression in response to alloantigen in liver allograft recipients and in vitro. Transplantation 1993; 5: 1159-1166.
18. Nolan CR, Saenz KP, Thomas CA, Murphy KD. Role of the eosinophil in chronic vascular rejection of renal allografts. Am J Kidney Dis 1995; 4: 634-642.
19. Trull A, Steel L, Cornelissen J et al. Association between blood eosinophil counts and acute cardiac and pulmonary allograft rejection. J Heart Lung Transplant 1998; 5: 517-524.
20. Ten RM, Gleich GJ, Holley KE, Perkins JD, Torres VE. Eosinophil granule major basic protein in acute renal allograft rejection. Transplantation 1989; 6: 959-963.
21. Goldman M, Le Moine A, Braun M, Flamand V, Abramowicz D. A role for eosinophils in transplant rejection. Trends Immunol 2001; 5: 247-251.
22. Hackstein H, Kluter H, Fricke L, Hoyer J, Bein G. The IL-4 receptor α-chain variant Q576R is strongly associated with decreased kidney allograft survival. Tissue Antigens 1999; 5: 471-477.
23. Sayegh MH, Turka LA. The role of T-cell costimulatory activation pathways in transplant rejection. N Engl J Med 1998; 1813-1821.
24. Kirk AD, Harlan DM, Armstrong NN et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997; 16: 8789-8794.
25. Kirk AD, Burkly LC, Batty DS et al. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. Nat Med 1999; 6: 686-693.
26. Yamada A, Sayegh MH. The CD154/CD40 costimulatory pathway in transplantation. Transplantation 2002: S36-S39.
27. Larsen CP, Elwood ET, Alexander DZ et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996; 6581: 434-438.
28. Sharpe AH, Freeman G. The B7-CD28 superfamily. Nat Rev 2002: 116-126.
29. Ozkaynak E, Gao W, Shemmeri N et al. Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection. Nat Immunol 2001; 7: 591-596.
30. Ye Q, Fraser CC, Gao W et al. Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival. J Exp Med 2002; 6: 795-800.
31. Yamada A, Kishimoto K, Dong VM et al. CD28-independent costimulation of T cells in alloimmune responses. J Immunol 2001; 1: 140-146.
32. Haspot F, Villemain F, Laflamme G et al. Differential effect of CD28 versus B7 blockade on direct pathway of allorecognition and self-restricted responses. Blood 2002; 6: 2228-2234.
33. Szot GL, Zhou P, Rulifson I et al. Different mechanisms of cardiac allograft rejection in wild type and CD28-deficient mice. Am J Transplant 2002: 38-46.
34. Williams MA, Trambley J, Ha J et al. Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts. J Immunol 2000; 12: 6849-6857.
35. Trambley J, Bingaman AW, Lin A et al. Asialo GM1 (+) CD8 (+) T cells play a critical role in costimulation blockade-resistant allograft rejection. J Clin Invest 1999; 12: 1715-1722.
36. Rosenberg AS, Singer A. Cellular basis of skin allograft rejection. an in vivo model of immune-mediated tissue destruction. Annu Rev Immunol 1992; 10: 333-358.
37. Maim H, Corbascio M, Osterholm C et al. CTLA4ig induces long-term graft survival of allogeneic skin grafts and totally inhibits T-cell proliferation in LFA-1-deficient mice. Transplantation 2002; 2: 293-297.
38. Guo Z, Wang J, Meng L et al. Membrane lymphotoxin regulates CD8 (+) T cell-mediated intestinal allograft rejection. J Immunol 2001; 9: 4796-4800.
39. + T cells. J Immunol 1999; 5: 2358-2362.
40. Guo Z, Meng L, Kim O et al. CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway. Transplantation 2001; 9: 1351-1354.
41. Kreisel D, Krupnick AS, Gelman AE et al. Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: an alternative mechanism of allorecognition. Nat Med 2002; 3: 233-239.
42. + CTL accumulate within the graft epithelium during clinical renal allograft rejection. Transplantation 2001; 9: 1548-1555.
43. + T cells, transforming growth factor beta1 expression and rejection grade. Transplantation 2001; 2: 306-313.
44. Hancock WW, Sayegh MH, Zheng XG, Peach R, Linsley PS, Turka LA. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci USA 1996; 24: 13967-13972.
45. Li XC, Ima A, Li Y, Zheng XX, Malek TR, Strom TB. Blocking the common gamma-chain of cytokine receptors induces T cell apoptosis and long-term islet allograft survival. J Immunol 2000; 3: 1193-1199.
46. Li XC, Roy-Chaudhury P, Hancock WW et al. IL-2 and IL-4 double knockout mice reject islet allografts: a role for novel T cell growth factors in allograft rejection. J Immunol 1998; 2: 890-896.
47. Jones TR, Ha J, Williams MA et al. The role of the IL-2 pathway in costimulation blockade-resistant rejection of allografts. J Immunol 2002; 3: 1123-1130.
48. + regulatory cells? Immunity 2001; 4: 399-406.
49. + regulatory cells in acquired MHC tolerance. Immunol Rev 2001: 99-112.
50. Trambley J, Lin A, Elwood E et al. FasL is important in costimulation blockade-resistant skin graft rejection. Transplantation 2001; 4: 537-543.
51. Suzuki I, Fink PJ. Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand. J Exp Med 1998; 1: 123-128.
52. Manilay JO, Sykes M. Natural killer cells and their role in graft rejection. Curr Opin Immunol 1998; 5: 532-538.
53. Lanier LL. On guard-activating NK cell receptors. Nat Immunol 2001; 1: 23-27.
54. Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med 2002; 5: 625-636.
55. Gumperz JE, Brenner MB. CD1-specific T cells in microbial immunity. Curr Opin Immunol 2001; 4: 471-478.
56. Zijlstra M, Auchincloss H, Jr, Loring JM, Chase CM, Russell PS, Jaenisch R. Skin graft rejection by β2-microglobulin-deficient mice. J Exp Med 1992; 4: 885-893.
57. Kondo T, Morita K, Watarai Y et al. Early increased chemokine expression and production in murine allogeneic skin grafts is mediated by natural killer cells. Transplantation 2000; 5: 969-977.
58. Yoneda O, Imai T, Goda S et al. Fractalkine-mediated endothelial cell injury by NK cells. J Immunol 2000; 8: 4055-4062.
59. Umehara H, Bloom E, Okazaki T, Domae N, Imai T. Fractalkine and vascular injury. Trends Immunol 2001; 11: 602-607.
60. Piccioli D, Sbrana S, Melandri E, Valiante NM. Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J Exp Med 2002; 3: 335-341.
61. Maier S, Tertilt C, Chambron N et al. Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/-mice. Nat Med 2001; 5: 557-562.
62. Maier S, Tertilt C, Chambron N et al. Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/-mice. Nat Med 2001; 7: 557-562.