Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: An alternative mechanism of allorecognition

Nature Medicine

Volumn 8, Issue 3, 2002, Pages 233-239

  Kreisel, Daniel ^a   Krupnick, Alexander S ^a   Gelman, Andrew E ^a   Engels, Friederike H ^a   Popma, Sicco H ^a   Krasinskas, Alyssa M ^a   Balsara, Keki R ^a   Szeto, Wilson Y ^a   Turka, Laurence A ^a   Rosengard, Bruce R ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN;

ALLOGRAFT; ANTIGEN PRESENTING CELL; ARTICLE; CELL POPULATION; CELL SURVIVAL; DENDRITIC CELL; EFFECTOR CELL; ENDOTHELIUM CELL; GRAFT REJECTION; HEART GRAFT; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; MOLECULAR RECOGNITION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VASCULARIZATION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; GRAFT REJECTION; HEART TRANSPLANTATION; HISTOCOMPATIBILITY ANTIGENS; HUMANS; IN SITU NICK-END LABELING; INTERFERON TYPE II; INTERLEUKIN-2; INTERLEUKIN-4; ISOANTIGENS; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; MYOCARDIUM; SPLEEN; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HOMOLOGOUS;

EID: 18344378770     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0302-233     Document Type: Article

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