Dendritic cells prime in vivo alloreactive CD4 T lymphocytes toward type 2 cytokine- and TGF-β-producing cells in the absence of CD8 T cell activation

Journal of Immunology

Volumn 165, Issue 9, 2000, Pages 4994-5003

  Foucras, G ^a   Coudert, J D ^a   Coureau, C ^a   Guery, J C ^a  

^a CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0034327646     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.9.4994     Document Type: Article

References (58)

1. The regulation of immunity to Leishmania major
2. + T-cell subsets in autoimmunity
3. Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival?
4. Cytokine gene transcription in vascutarised organ grafts: Analysis using semiquantitative polymerase chain reaction
5. Infectious tolerance
6. Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells
7. Increased expression of la antigens on B cells after neonatal induction of lymphoid chimerism in mice: Role of interleukin 4
8. Enhanced type 2 and diminished type 1 cytokines in neonatal tolerance
9. Critical role of interteukin 4 in the induction of neonatal transplantation tolerance
10. Lethal host-versus-graft disease and hypereosinophilia syndrome in mice in the absence of major tiistocompatibility class I-T cell interactions
11. + T cells results in Th2 cytokine production and alternate mechanisms of allograft rejection
12. Critical roles for IL-4, IL-5, and eosinophils in chronic skin altograft rejection
13. The molecular basis of allorecognition
14. Induction of Th1 and Th2 immunity in neonatal mice
15. + T lymphocytes downregutate T helper celt type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection
16. + T cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection
17. + T cells
18. Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease
19. Self-reactive anti-class Th2 cell lines derived from gold salt-injected rats trigger B celt polyclonal activation and transfer autoimmunity in CD8-depteted normal syngeneic recipients
20. Natural killer cell receptors and MHC class I interactions
21. + T cells
22. 2-microglobulin-deficient mice
23. CD8 is needed for development of cytotoxic T cells but not helper T cells
24. Mice lacking MHC class II molecules
25. Bone marrow-derived dendritic cells pulsed with synthetic tumor peptides elicit protective and therapeutic antitumor immunity
26. Epitope specific binding of CD8 regulates activation of T cells and induction of cytotoxicity
27. Monoclonal antibodies against murine γ interferon
28. Two types of mouse helper T celt clone. III. Further differences in tymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally mono-specific bioassays, and monoclonal antibodies
29. The autocrine production of transforming growth factor-β1 during lymphocyte activation: A study with a monoclonal antibody-based ELISA
30. Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper I and T helper 2 populations
31. Non-MHC-linked Th2 cell development induced by soluble protein administration predicts susceptibility to Leishmania major infection
32. Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells
33. Migration of dendritic leukocytes from cardiac allografts into host spleens: A novel pathway for initiation of rejection
34. Regulation of immune responses by TGF-β
35. + T cells are not essential for T helper cell 2 immune responses
36. 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses
37. 2-microglobulin-dependent T cells are not necessary for alloantigen-induced Th2 responses after neonatal induction of lymphoid chimerism in mice
38. Mouse CD1-specific NK1 T cells: Development, specificity, and function
39. + T helper cell phenotype development in a T cell receptor-αβ-transgenic model
40. + T cells
41. Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance
42. Sequence analysis of peptides bound to MHC class II molecules
43. On the complexity of self
44. Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-A(d)
45. + T cell recognition of class II MHC molecules
46. Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells
47. Oral tolerance: Immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens
48. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
49. + T cells
50. T cell genetic background determines default T helper phenotype development in vitro
51. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling
52. The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells
53. Generation, persistence, and modulation of Th0 effector cells: Role of autocrine IL-4 and IFN-γ
54. Antiproliferative effect of IFN-γ in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ
55. Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper I (Th1) and Th2 cells
56. IL-5 mediates eosinophilic rejection of major histocompatibility complex class II-disparate skin allografts in mice
57. Nucleotide sequence of mutant I-A β bm12 gene is evidence for genetic exchange between mouse immune response genes
58. + T cell lines