IL-5 mediates eosinophilic rejection of MHC class II-disparate skin allografts in mice

Journal of Immunology

Volumn 163, Issue 7, 1999, Pages 3778-3784

  Le Moine, Alain ^a,b   Surquin, Murielle ^a,b   Demoor, François Xavier ^a   Noël, Jean Christophe ^b   Nahori, Marie Anne ^d   Pretolani, Marina ^c   Flamand, Véronique ^a   Braun, Michel Y ^a   Goldman, Michel ^a   Abramowicz, Daniel ^b  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b ERASME HOSPITAL   (Belgium)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; INTERLEUKIN 5; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOTOXICITY; EOSINOPHIL; GRAFT REJECTION; HELPER CELL; LYMPH NODE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN ALLOGRAFT;

ACUTE DISEASE; ANIMALS; ANTIGENS, CD95; CELL MOVEMENT; CYTOKINES; EOSINOPHILS; FAS LIGAND PROTEIN; FEMALE; GRAFT REJECTION; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNE SERA; INTERLEUKIN-5; LIGANDS; LYMPH NODES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED MRL LPR; MICE, MUTANT STRAINS; RNA, MESSENGER; SKIN TRANSPLANTATION;

EID: 0033214399     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Rosenberg, A. S., and A. Singer. 1992. Cellular basis of skin allograft rejection: an in vivo model of immune-mediated tissue destruction. Annu. Rev. Immunol. 10:333.
2. Van Parijs, L., and A. K. Abbas. 1996. Role of Fas-mediated cell death in the regulation of immune responses. Curr. Opin. Immunol. 8:355.
3. Hahn, S., R. Gehri, and P. Erb. 1995. Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol. Rev. 146:57.
4. Kalams, S. A., and B. D. Walker. 1999. The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J. Exp. Med. 188:2199.
5. + T cells during their development. J. Immunol. 155:1091.
6. DeKruyff, R. H., L. V. Rizzo, and D. T. Umetsu. 1993. Induction of immunoglobulin synthesis by CD4+ T cell clones. Semin. Immunol. 5:421.
7. Valujskikh, A., D. Matesic, A. Gilliam, D. Anthony, T. M. Haqqi, and P. S. Heeger. 1998. T cells reactive to a single immunodominant self-restricted allopeptide induce skin graft rejection in mice. J. Clin. Invest. 101:1398.
8. Goto, M., Y. Yamaguchi, O. Ichiguchi, N. Miyanari, E. Akizuki, F. Matsumura, T. Matsuda, K. Mori, and M. Ogawa. 1997. Phenotype and localization of macrophages expressing inducible nitric oxide synthase in rat hepatic allograft rejection. Transplantation 64:303.
9. Sirak, J., C. G. Orosz, E. Wakely, and A. M. VanBuskirk. 1997. Alloreactive delayed-type hypersensitivity in graft recipients: complexity of responses and divergence from acute rejection. Transplantation 63:1300.
10. - mice are sufficient to mediate the rejection of MHC class II or class I disparate skin grafts. J. Immunol. 156:4114.
11. Sekine, Y., L. K. Bowen, K. M. Heidler, N. Van Rooijen, J. W. Brown, O. W. Cummings, and D. S. Wilkes. 1997. Role of passenger leukocytes in allograft rejection: effect of depletion of donor alveolar macrophages on the local production of TNF-α, T helper 1/T helper 2 cytokines, IgG subclasses, and pathology in a rat model of lung transplantation. J. Immunol. 159:4084.
12. Gomez Flores, R., C. Rodriguez Padilla, R. T. Mehta, L. Galan Wong, E. Mendoza Gamboa, and R. Tamez Guerra. 1997. Nitric oxide and TNF-α production by murine peritoneal macrophages activated with a novel 20-kDa protein isolated from Bacillus thuringiensis var. thuringiensis parasporal bodies. J. Immunol. 158:3796.
13. Nadeau, K. C., H. Azuma, and N. L. Tilney. 1995. Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1. Proc. Natl. Acad. Sci. USA 92:8729.
14. Yang, X., N. Chowdhury, B. Cai, J. Brett, C. Marboe, R. R. Sciacca, R. E. Michler, and P. J. Cannon. 1994. Induction of myocardial nitric oxide synthase by cardiac allograft rejection. J. Clin. Invest. 94:714.
15. Schook, L. B., H. Albrecht, P. Gallay, and C. V. Jongeneel. 1994. Cytokine regulation of TNF-α mRNA and protein production by unprimed macrophages from C57BL/6 and NZW mice. J. Leukocyte Biol. 56:514.
16. + T cells. J. Immunol. 161:5236.
17. + T cells results in Th2 cytokine production and alternate mechanisms of allograft rejection. Transplantation 59:1155.
18. Martinez, O. M., N. L. Ascher, L. Ferrell, J. Villanueva, J. Lake, J. P. Roberts, and S. M. Krams. 1993. Evidence for a nonclassical pathway of graft rejection involving interleukin 5 and eosinophils. Transplantation 55:909.
19. + T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Respir. Dis. 146:374.
20. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4:15.
21. Foster, P. S., S. P. Hogan, A. J. Ramsay, K. I. Matthaei, and I. G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195.
22. Kroegel, C., J. C. Virchow, Jr., W. Luttmann, C. Walker, and J. A. Warner. 1994. Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part I). Eur. Respir. J. 7:519.
23. Billingham, R., and Medawar PB. 1951. The technique of free skin grafting in mammals. J. Exp. Biol. 28:385.
24. Donckier, V., M. Wissing, C. Bruyns, D. Abramowicz, M. Lybin, M. L. Vanderhaeghen, and M. Goldman. 1995. Critical role of interleukin 4 in the induction of neonatal transplantation tolerance. Transplantation 59:1571.
25. Schumacher, J. H., A. O'Garra, B. Shrader, A. van Kimmenade, M. W. Bond, T. R. Mosmann, and R. L. Coffman. 1988. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J. Immunol. 141:1576.
26. + T lymphocyte and eosinophil infiltration into the mouse peritoneal cavity. J. Immunol. 157:377.
27. Rosenberg, A. S., D. S. Finbloom, T. G. Maniero, P. H. Van der Meide, and A. Singer. 1990. Specific prolongation of MHC class II disparate skin allografts by in vivo administration of anti-IFN-γ monoclonal antibody. J. Immunol. 144: 4648.
28. Russell, P. S., C. M. Chase, H. J. Winn, and R. B. Colvin. 1994. Coronary atherosclerosis in transplanted mouse hearts. III. Effects of recipient treatment with a monoclonal antibody to interferon-γ. Transplantation 57:1367.
29. Gleich, G. J., C. R. Adolpson, and K. M. Leiferman. 1993. The biology of the eosinophilic leukocyte. Annu. Rev. Med. 44:85.
30. Rothenberg, M. E. 1998. Eosinophilia. N. Engl. J. Med. 338:1592.
31. + T cells in the anti-tumor immune response. J. Exp. Med. 1988:2357.
32. Tepper, R. I., R. L. Coffman, and P. Leder. 1992. An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science 257:548.
33. Sanderson, C. J. 1992. Interleukin-5, eosinophils, and disease. Blood 79:3101.
34. Coffman, R. L., B. W. Seymour, S. Hudak, J. Jackson, and D. Rennick. 1989. Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science 245:308.
35. Mould, A. W., K. I. Matthaei, I. G. Young, and P. S. Foster. 1997. Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice. J. Clin. Invest. 99:1064.
36. Backer, M. B., N. H. Altman, E. R. Podack, and R. B. Levy. 1996. The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice. J. Exp. Med. 183:2646.
37. Linder, G., V. A. Botchkarev, N. V. Botchkareva, G. Ling, C. van der Veen, and R. Paus. 1997. Analysis of apoptosis during hair follicle regression. Am. J. Pathol. 151:1601.
38. Viard, I., P. Wehrli, R. Bullani, P. Schneider, N. Holler, D. Salomon, T. Hunziker, J. H. Saurat, J. Tschopp, and L. E. French. 1998. Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin. Science 282:490.
39. + T cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection. Eur. J. Immunol. 27:3341.
40. Hussell, T., A. Georgiou, T. E. Sparer, S. Matthews, P. Pala, and P. J. M. Openshaw. 1998. Host genetic determinants of vaccine-induced eosinophilia during respiratory syncytial virus infection. J. Immunol. 161:6215.
41. Tang, H., C. sharp, K. P. Peterson, and H. Braley-Mullen. 1998. IFN-gamma-deficient mice develop severe granulomatous experimental autoimmune thyroiditis with eosinophil and infiltration in thyroids. J. Immunol. 160:5105.
42. + T cell responses: the alternative approaches. Annu. Rev. Immunol. 15:297.
43. Martinez, O. M., J. C. Villanueva, J. Lake, J. P. Roberts, N. L. Ascher, and S. M. Krams. 1993. IL-2 and IL-5 gene expression in response to alloantigen in liver allograft recipients and in vitro. Transplantation 55:1159.
44. de Groen, P. C., G. M. Kephart, G. J. Gleich, and J. Ludwig. 1994. The eosinophil as an effector cell of the immune response during hepatic allograft rejection. Hepatology 20:654.
45. Nolan, C. R., K. P. Saenz, C. A. Thomas, and K. D. Murphy. 1995. Role of the eosinophil in chronic vascular rejection of renal allografts. Am. J. Kidney Dis. 26:634.
46. Ten, R. M., G. J. Gleich, K. E. Holley, J. D. Perkins, and V. E. Torres. 1989. Eosinophil granule major basic protein in acute renal allograft rejection. Transplantation 47:959.