Central role for Cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts

Genes to Cells

Volumn 5, Issue 6, 2000, Pages 439-452

  Mimura, Satoru ^a   Masuda, Taro ^a   Matsui, Tomoko ^a   Takisawa, Haruhiko ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; DNA DIRECTED DNA POLYMERASE ALPHA; REPLICATION PROTEIN A;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CHROMATIN; CONTROLLED STUDY; DNA REPLICATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; XENOPUS;

ANIMALS; CARRIER PROTEINS; CHROMATIN; DNA POLYMERASE I; DNA POLYMERASE II; DNA REPLICATION; DNA-BINDING PROTEINS; MACROMOLECULAR SUBSTANCES; MODELS, GENETIC; NUCLEAR PROTEINS; OOCYTES; PROLIFERATING CELL NUCLEAR ANTIGEN; REPLICATION ORIGIN; REPLICATION PROTEIN A; S PHASE; SACCHAROMYCES CEREVISIAE PROTEINS; XENOPUS;

ANIMALIA; EUKARYOTA;

EID: 0033936230     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.2000.00340.x     Document Type: Article

References (39)

1. Adachi, Y. & Laemmli, U.K. (1992) Identification of nuclear prereplication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A. J. Cell Biol. 119, 1-15.
2. Adachi, Y. & Laemmli, U.K. (1994) Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts. EMBO J. 13, 4153-4164.
3. Aparicio, O.M., Weinstein, D.M. & Bell, S.P. (1997) Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase. Cell 91, 59-69.
4. Aparicio, O.M., Stout, A.M. & Bell, S.P. (1999) Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication. Proc. Natl. Acad. Sci. USA 96, 9130-9135.
5. Baker, T.A. & Bell, S.P. (1998) Polymerases and the replisome: machines within machines. Cell 92, 295-305.
6. Bhaumik, D. & Wang, T.S.-F. (1998) Mutational effect of fission yeast Polαa on cell cycle events. Mol. Biol. Cell 9, 2107-2123.
7. Borowiec, J.A., Dean, F.B., Bullock, P.A. & Hurwitz, J. (1990) Binding and unwinding - how T antigen engages the SV40 origin of DNA replication. Cell 60, 181-184.
8. Challberg, M.D. & Kelly, T.J. (1989) Animal virus DNA replication. Annu. Rev. Biochem. 58, 671-717.
9. Dalton, S. & Hopwood, B. (1997) Characterization of Cdc47p-minichromosome maintenance complexes in Saccharomyces cerevisiae: identification of Cdc45p as a subunit. Mol. Cell. Biol. 17, 5867-5875.
10. Dua, R., Levy, D.L. & Campbell, J.L. (1999) Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pole and its unexpected ability to support growth in the absence of the DNA polymerase domain. J. Biol. Chem. 274, 22283-22288.
11. + encodes DNA polymerase ε and is required for chromosomal replication but not for the S phase checkpoint. Proc. Natl. Acad. Sci. USA 94, 12491-12496.
12. Dutta, A. & Bell, S.P. (1997) Initiation of DNA replication in eukaryotic cells. Annu. Rev. Cell Dev. Biol. 13, 293-332.
13. Fanning, E. & Knippers, R. (1992) Structure and function of simian virus 40 large tumor antigen. Annu. Rev. Biochem. 61, 55-85.
14. Hardy, C.F. (1997) Identification of Cdc45p, an essential factor required for DNA replication. Gene 187, 239-246.
15. Hennessy K.M., Lee, A., Chen, E. & Botstein, D. (1991) A group of interacting yeast DNA replication genes. Genes Dev. 5, 958-969.
16. Hopwood, B. & Dalton, S. (1996) Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication. Proc. Natl. Acad. Sci. USA 93, 12309-12314.
17. Ishimi, Y. (1997) A DNA helicase activity is associated with an Mcm4, -6, and -7 protein complex. J. Biol. Chem. 272, 24508-24513.
18. Kesti, T., Frantti, H. & Syväoja, J.E. (1993) Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon. J. Biol. Chem. 268, 10238-10245.
19. Kesti, T., Flick, K., Keränen, S., Syväoja, J.E. & Wittenberg, C. (1999) DNA polymerase ε catalytic domains are dispensable for DNA replication, DNA repair, and cell viability. Mol. Cell 3, 679-685.
20. Kubota, Y. & Takisawa, H. (1993) Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts. J. Cell Biol. 123, 1321-1331.
21. Kubota, Y., Mimura, S., Nishimoto, S., Takisawa, H. & Nojima, H. (1995) Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor. Cell 81, 601-609.
22. Kubota, Y., Mimura, S., Nishimoto, S., Masuda, T., Nojima, H. & Takisawa, H. (1997) Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs. EMBO J. 16, 3320-3331.
23. Kukimoto, I., Igaki, H. & Kanda, T. (1999) Human CDC45 protein binds to minichromosome maintenance7 protein and the p70 subunit of DNA polymerase α. Eur. J. Biochem. 265, 936-943.
24. Masumoto, H., Sugino, A. & Araki, H. (2000) Dpb11 controls the association between DNA polymerase alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol. Cell. Biol. 20, 2809-2817.
25. McGarry, T.J. & Kirschner, M.W. (1998) Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell 93, 1043-1053.
26. Mimura, S. & Takisawa, H. (1998) Xenopus Cdc45-dependent loading of DNA polymerase α onto chromatin under the control of S-phase Cdk. EMBO J. 17, 5699-5707.
27. Miyake, S. & Yamashita, S. (1998) Identification of sna41 gene, which is the suppressor of nda4 mutation and is involved in DNA replication in Schizosaccharomyces pombe. Genes Cells 3, 157-166.
28. Morrison, A., Araki, H., Clark, A.B., Hamatake, R.K. & Sugino, A. (1990) A third essential DNA polymerase in S. cerevisiae. Cell 62, 1143-1151.
29. Owens, J.C., Detweiler, C.S. & Li, J.J. (1997) CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication. Proc. Natl. Acad. Sci. USA 94, 12521-12526.
30. Reid, R.J., Fiorani, P., Sugawara, M. & Bjornsti, M.A. (1999) CDC45 and DPB11 are required for processive DNA replication and resistance to DNA topoisomerase I- mediated DNA damage. Proc. Natl. Acad. Sci. USA 96, 11440-11445.
31. Stillman, B. (1989) Initiation of eukaryotic DNA replication in vitro. Annu. Rev. Cell Biol. 5, 197-245.
32. Stillman, B. (1996) Cell cycle control of DNA replication. Science 274, 1659-1664.
33. Tanaka, T. & Nasmyth, K. (1998) Association of RPA with chromosomal replication origins requires an Mem protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases. EMBOJ. 17, 5182-5191.
34. Tye, B.K. (1999) MCM proteins in DNA replication. Annu. Rev. Biochem. 68, 649-686.
35. Waga, S. & Stillman, B. (1994) Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro. Nature 369, 207-212.
36. Walter, J. & Newport, J. (2000) Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase α. Mol. Cell. 5, 617-627.
37. Wang, T.S.-F. (1991) Eukaryotic DNA polymerases. Annu. Rev. Biochem. 60, 513-552.
38. Zou, L. & Stillman, B. (1998) Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280, 593-596.
39. Zou, L., Mitchell, J. & Stillman, B. (1997) CDC45, a novel yeast gene that functions with the origin recognition complex and Mem proteins in initiation of DNA replication. Mol. Cell. Biol. 17, 553-563.