Ribonucleases: From prototypes to therapeutic targets?

Current Medicinal Chemistry

Volumn 10, Issue 9, 2003, Pages 779-785

  Loverix, Stefan ^a   Steyaert, Jan ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Catalysis; Inhibitor design; Pentavalent phosphorus; RNA cleavage; RNase A; RNase T1; Transition state analog

Indexed keywords

ALLERGEN; ANGIOGENIN; CELL EXTRACT; NEUROTOXIN; RIBONUCLEASE A; RIBONUCLEASE T1; URIDINE DERIVATIVE; VANADIC ACID;

CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DEPOLYMERIZATION; DISSOCIATION CONSTANT; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME SUBSTRATE; PHASE TRANSITION; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTON TRANSPORT; REVIEW; RNA CLEAVAGE; RNA TRANSCRIPTION;

ANIMALS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; OXYGEN; RIBONUCLEASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037269273     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033457845     Document Type: Review

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