How much gets there and what does it do?: The need for better pharmacokinetic and pharmacodynamic endpoints in contemporary drug discovery and development

Current Pharmaceutical Design

Volumn 9, Issue 11, 2003, Pages 891-902

  Workman, Paul ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 NITRO 1 IMIDAZOLYL) N (3,3,3 TRIFLUORO 2 HYDROXYPROPYL)ACETAMIDE; AAG 17; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; HEAT SHOCK PROTEIN 90; IMATINIB; NEW DRUG; NITROIMIDAZOLE DERIVATIVE; ONCOPROTEIN; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; RAF PROTEIN; TRASTUZUMAB; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; BIOINFORMATICS; CLINICAL RESEARCH; DRUG ACTIVITY; DRUG APPROVAL; DRUG DESIGN; DRUG DOSE REGIMEN; DRUG INDUSTRY; DRUG METABOLISM; DRUG RESEARCH; DRUG SCREENING; DRUG TARGETING; ECONOMIC EVALUATION; GASTROINTESTINAL TUMOR; GENE SEQUENCE; HUMAN; HYPOXIA; LEUKEMIA; MEDICAL TECHNOLOGY; NEUROTOXICITY; NONHUMAN; PHARMACODYNAMICS; PHARMACOGENETICS; PRIORITY JOURNAL; PROTEOMICS; REVIEW; TARGET CELL;

COSTS AND COST ANALYSIS; DRUG DESIGN; DRUG THERAPY; HUMANS; PHARMACOKINETICS; PHARMACOLOGY, CLINICAL; TECHNOLOGY, PHARMACEUTICAL;

EID: 0037237884     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612033455279     Document Type: Review

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