Quantitative structure - Activity relationships (QSARs) of thrombin inhibitors: Review, evaluation an comparative analysis

Current Medicinal Chemistry

Volumn 10, Issue 7, 2003, Pages 525-577

  Kontogiorgis, Christos A ^a   Hadjipavlou Litina, Dimitra ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Hydrophobicity; Inhibitors; QSAR; Steric factors; Thrombin

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURY)INDAZOLE DERIVATIVE; AMINOINMINOMETHYLPIPERIDINE DERIVATIVE; AMINOPYRIDINE DERIVATIVE; ANTICOAGULANT AGENT; APTAMER; ARGATROBAN; ARGININE DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; BORONIC ACID DERIVATIVE; HEPARIN; HETEROCYCLIC COMPOUND; HIRUDIN DERIVATIVE; HIRULOG; INDAZOLE DERIVATIVE; INOGATRAN; LOW MOLECULAR WEIGHT HEPARIN; PIPERIDINE DERIVATIVE; PYRIDINIUM DERIVATIVE; RECOMBINANT HIRUDIN; SULFAGUANIDINE; THROMBIN; THROMBIN INHIBITOR; TOSYLARGININE METHYL ESTER; UNCLASSIFIED DRUG; WARFARIN;

CALCULATION; CLINICAL TRIAL; DRUG ACTIVITY; DRUG DESIGN; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; HUMAN; HYDROPHOBICITY; PHYSICAL CHEMISTRY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; STEREOCHEMISTRY; THROMBOSIS;

ANTITHROMBINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037233022     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033457935     Document Type: Review

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