-
1
-
-
0031919849
-
Jaks and STATS: Biological implications
-
Leonard WJ, O'Shea JJ. Jaks and STATS: Biological implications. Annu Rev Immunol. 1998;16:293-322.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
2
-
-
0025848163
-
Interaction of the IL-2 receptor with the src-family kinase p56lck: Identification of novel intermolecular association
-
Hatakeyama M, Kono T, Kobayashi N, et al. Interaction of the IL-2 receptor with the src-family kinase p56lck: Identification of novel intermolecular association. Science. 1991;252:1523-1528.
-
(1991)
Science
, vol.252
, pp. 1523-1528
-
-
Hatakeyama, M.1
Kono, T.2
Kobayashi, N.3
-
3
-
-
0026028846
-
T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck
-
Horak ID, Gress RE, Lucas PJ, Horak EM, Waldmann TA, Bolen JB. T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck. Proc Natl Acad Sci U S A. 1991;88:1996-2000.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 1996-2000
-
-
Horak, I.D.1
Gress, R.E.2
Lucas, P.J.3
Horak, E.M.4
Waldmann, T.A.5
Bolen, J.B.6
-
4
-
-
0028964465
-
Cytokine signaling through nonreceptor protein tyrosine kinases
-
Taniguchi T. Cytokine signaling through nonreceptor protein tyrosine kinases. Science. 1995;268:251-255.
-
(1995)
Science
, vol.268
, pp. 251-255
-
-
Taniguchi, T.1
-
5
-
-
0028339282
-
Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2
-
Johnston JA, Kawamura M, Kirken RA, et al. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature. 1994;370:151-153.
-
(1994)
Nature
, vol.370
, pp. 151-153
-
-
Johnston, J.A.1
Kawamura, M.2
Kirken, R.A.3
-
6
-
-
0028244396
-
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
-
Witthuhn BA, Silvennoinen O, Miura O, et al. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature. 1994;370:153-157.
-
(1994)
Nature
, vol.370
, pp. 153-157
-
-
Witthuhn, B.A.1
Silvennoinen, O.2
Miura, O.3
-
7
-
-
0027955433
-
The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation
-
Ravichandran KS, Burakoff SJ. The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation. J Biol Chem. 1994;269:1599-1602.
-
(1994)
J Biol Chem
, vol.269
, pp. 1599-1602
-
-
Ravichandran, K.S.1
Burakoff, S.J.2
-
8
-
-
0030049012
-
Interleukin-2 receptor signaling mechanisms
-
Karnitz LM, Abraham RT. Interleukin-2 receptor signaling mechanisms. Adv Immunol. 1996;61:147-199.
-
(1996)
Adv Immunol
, vol.61
, pp. 147-199
-
-
Karnitz, L.M.1
Abraham, R.T.2
-
9
-
-
0028908804
-
Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP
-
Monfar M, Lemon KP, Grammer TC, et al. Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. Mol Cell Biol. 1995;15:326-337.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 326-337
-
-
Monfar, M.1
Lemon, K.P.2
Grammer, T.C.3
-
10
-
-
0030908525
-
Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase
-
Reif K, Burgering BM, Cantrell DA. Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase. J Biol Chem. 1997;272:14426-14433.
-
(1997)
J Biol Chem
, vol.272
, pp. 14426-14433
-
-
Reif, K.1
Burgering, B.M.2
Cantrell, D.A.3
-
11
-
-
0027279176
-
How receptor tyrosine kinases activate Ras
-
Schlessinger J. How receptor tyrosine kinases activate Ras. Trends Biochem Sci. 1993;18:273-275.
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 273-275
-
-
Schlessinger, J.1
-
12
-
-
0029972926
-
Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling
-
Ravichandran KS, Igras V, Shoelson SE, Fesik SW, Burakoff SJ. Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling. Proc Natl Acad Sci U S A. 1996;93:5275-5280.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5275-5280
-
-
Ravichandran, K.S.1
Igras, V.2
Shoelson, S.E.3
Fesik, S.W.4
Burakoff, S.J.5
-
13
-
-
0342820096
-
Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway
-
Gonzalez-Garcia A, Merida I, Martinez AC, Carrera AC. Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway. J Biol Chem. 1997;272:10220-10226.
-
(1997)
J Biol Chem
, vol.272
, pp. 10220-10226
-
-
Gonzalez-Garcia, A.1
Merida, I.2
Martinez, A.C.3
Carrera, A.C.4
-
14
-
-
0030890933
-
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad Sci U S A. 1997;94:3627-3632.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
15
-
-
0026316011
-
Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase
-
Remillard B, Petrillo R, Maslinski W, et al. Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase. J Biol Chem. 1991;266:14167-14170.
-
(1991)
J Biol Chem
, vol.266
, pp. 14167-14170
-
-
Remillard, B.1
Petrillo, R.2
Maslinski, W.3
-
16
-
-
0028988329
-
Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: Possible link with the c-myc induction pathway
-
Minami Y, Nakagawa Y, Kawahara A, et al. Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: Possible link with the c-myc induction pathway. Immunity. 1995;2:89-100.
-
(1995)
Immunity
, vol.2
, pp. 89-100
-
-
Minami, Y.1
Nakagawa, Y.2
Kawahara, A.3
-
17
-
-
0028363554
-
Interleukin 2 mediates p72syk activation in peripheral blood lymphocytes
-
Qin S, Inazu T, Yang C, Sada K, Taniguchi T, Yamamura H. Interleukin 2 mediates p72syk activation in peripheral blood lymphocytes. FEBS Lett. 1994;345:233-236.
-
(1994)
FEBS Lett
, vol.345
, pp. 233-236
-
-
Qin, S.1
Inazu, T.2
Yang, C.3
Sada, K.4
Taniguchi, T.5
Yamamura, H.6
-
18
-
-
0033997615
-
Tyrosine kinase SYK: Essential functions for immunoreceptor signalling
-
Turner M, Schweighoffer E, Colucci F, Di Santo JP, Tybulewicz VL. Tyrosine kinase SYK: Essential functions for immunoreceptor signalling. Immunol Today. 2000;21:148-154.
-
(2000)
Immunol Today
, vol.21
, pp. 148-154
-
-
Turner, M.1
Schweighoffer, E.2
Colucci, F.3
Di Santo, J.P.4
Tybulewicz, V.L.5
-
19
-
-
0029670081
-
Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
-
Law CL, Chandran KA, Sidorenko SP, Clark EA. Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk. Mol Cell Biol. 1996;16:1305-1315.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1305-1315
-
-
Law, C.L.1
Chandran, K.A.2
Sidorenko, S.P.3
Clark, E.A.4
-
20
-
-
0030018795
-
Syk-dependent phosphorylation of Shc: A potential link between FcεRI and the Ras/mitogenactivated protein kinase signaling pathway through SOS and Grb2
-
Jabril-Cuenod B, Zhang C, Scharenberg AM, et al. Syk-dependent phosphorylation of Shc: A potential link between FcεRI and the Ras/mitogenactivated protein kinase signaling pathway through SOS and Grb2. J Biol Chem. 1996;271:16268-16272.
-
(1996)
J Biol Chem
, vol.271
, pp. 16268-16272
-
-
Jabril-Cuenod, B.1
Zhang, C.2
Scharenberg, A.M.3
-
21
-
-
0034613169
-
Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress
-
Ding J, Takano T, Gao S, et al. Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress. J Biol Chem. 2000;275:30873-30877.
-
(2000)
J Biol Chem
, vol.275
, pp. 30873-30877
-
-
Ding, J.1
Takano, T.2
Gao, S.3
-
22
-
-
0034254421
-
B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase
-
Pogue SL, Kurosaki T, Bolen J, Herbst R. B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase. J Immunol. 2000;165:1300-1306.
-
(2000)
J Immunol
, vol.165
, pp. 1300-1306
-
-
Pogue, S.L.1
Kurosaki, T.2
Bolen, J.3
Herbst, R.4
-
23
-
-
0032481142
-
Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vavl
-
Miranti CK, Leng L, Maschberger P, Brugge JS, Shattil SJ. Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vavl. Curr Biol. 1998;8:1289-1299.
-
(1998)
Curr Biol
, vol.8
, pp. 1289-1299
-
-
Miranti, C.K.1
Leng, L.2
Maschberger, P.3
Brugge, J.S.4
Shattil, S.J.5
-
24
-
-
0032100476
-
Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: Identification of perforin and granzyme B mobilization by functional ERK2
-
Wei S, Gamero AM, Liu JH, et al. Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: Identification of perforin and granzyme B mobilization by functional ERK2. J Exp Med. 1998;187:1753-1765.
-
(1998)
J Exp Med
, vol.187
, pp. 1753-1765
-
-
Wei, S.1
Gamero, A.M.2
Liu, J.H.3
-
25
-
-
0031015986
-
A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain
-
Klippel A, Kavanaugh WM, Pot D, Williams LT. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. Mol Cell Biol. 1997;17:338-344.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 338-344
-
-
Klippel, A.1
Kavanaugh, W.M.2
Pot, D.3
Williams, L.T.4
-
26
-
-
0029045870
-
Reconstitution of interactions between tyrosine kinases and the high affinity IgE receptor which are controlled by receptor clustering
-
Scharenberg AM, Lin S, Cuenod B, Yamamura H, Kinet JP. Reconstitution of interactions between tyrosine kinases and the high affinity IgE receptor which are controlled by receptor clustering. EMBO J. 1995;14:3385-3394.
-
(1995)
EMBO J
, vol.14
, pp. 3385-3394
-
-
Scharenberg, A.M.1
Lin, S.2
Cuenod, B.3
Yamamura, H.4
Kinet, J.P.5
-
27
-
-
0034614935
-
Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells
-
Hong-Geller E, Cerione RA. Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells. J Cell Biol. 2000;148:481-494.
-
(2000)
J Cell Biol
, vol.148
, pp. 481-494
-
-
Hong-Geller, E.1
Cerione, R.A.2
-
28
-
-
0034330547
-
Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
-
Jiang K, Zhong B, Gilvary DL, et al. Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells. Nat Immunol. 2000;1:419-425.
-
(2000)
Nat Immunol
, vol.1
, pp. 419-425
-
-
Jiang, K.1
Zhong, B.2
Gilvary, D.L.3
-
29
-
-
0021828496
-
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
-
Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature. 1985;315:239-242.
-
(1985)
Nature
, vol.315
, pp. 239-242
-
-
Whitman, M.1
Kaplan, D.R.2
Schaffhausen, B.3
Cantley, L.4
Roberts, T.M.5
-
30
-
-
0028072499
-
Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol
-
Oliver JM, Burg DL, Wilson BS, McLaughlin JL, Geahlen RL. Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol. J Biol Chem. 1994;269:29697-29703.
-
(1994)
J Biol Chem
, vol.269
, pp. 29697-29703
-
-
Oliver, J.M.1
Burg, D.L.2
Wilson, B.S.3
McLaughlin, J.L.4
Geahlen, R.L.5
-
31
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Vlahos CJ, Matter WF, Hui KY, Brown RF. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem. 1994;269:5241-5248.
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
32
-
-
0033491981
-
Biology of the interleukin-2 receptor
-
Nelson BH, Willerford DM. Biology of the interleukin-2 receptor. Adv Immunol. 1998;70:1-81
-
(1998)
Adv Immunol
, vol.70
, pp. 1-81
-
-
Nelson, B.H.1
Willerford, D.M.2
-
33
-
-
0026091203
-
IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase
-
Merida I, Diez E, Gaulton GN. IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase. J Immunol. 1991;147:2202-2207.
-
(1991)
J Immunol
, vol.147
, pp. 2202-2207
-
-
Merida, I.1
Diez, E.2
Gaulton, G.N.3
-
34
-
-
0029965452
-
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction
-
Wymann MP, Bulgarelli-Leva G, Zvelebil M, et al. Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction. Mol Cell Biol. 1996;16:1722-1733.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1722-1733
-
-
Wymann, M.P.1
Bulgarelli-Leva, G.2
Zvelebil, M.3
-
35
-
-
0028837170
-
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
-
Nobes CD, Hawkins P, Stephens L, Hall A. Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J Cell Sci. 1995;108:225-233.
-
(1995)
J Cell Sci
, vol.108
, pp. 225-233
-
-
Nobes, C.D.1
Hawkins, P.2
Stephens, L.3
Hall, A.4
-
36
-
-
0031841211
-
Involvement of phosphoinositide 3-kinase and Rac in membrane ruffling induced by IL-2 in T cells
-
Arrieumerlou C, Donnadieu E, Brennan P, et al. Involvement of phosphoinositide 3-kinase and Rac in membrane ruffling induced by IL-2 in T cells. Eur J Immunol. 1998;28:1877-1885.
-
(1998)
Eur J Immunol
, vol.28
, pp. 1877-1885
-
-
Arrieumerlou, C.1
Donnadieu, E.2
Brennan, P.3
-
37
-
-
0034282454
-
GTPases and phosphatidylinositol 3-kinase are critical for insulin-like growth factor-l-mediated Schwann cell motility
-
Cheng HL, Steinway ML, Russell JW, Feldman EL. GTPases and phosphatidylinositol 3-kinase are critical for insulin-like growth factor-l-mediated Schwann cell motility. J Biol Chem. 2000;275:27197-27204.
-
(2000)
J Biol Chem
, vol.275
, pp. 27197-27204
-
-
Cheng, H.L.1
Steinway, M.L.2
Russell, J.W.3
Feldman, E.L.4
-
38
-
-
0035253356
-
Rac and phosphatidylinositol 3-kinase regulate the protein kinase B in Fc epsilon RI signaling in RBL 2H3 mast cells
-
Djouder N, Schmidt G, Frings M, Cavalie A, Thelen M, Aktories K. Rac and phosphatidylinositol 3-kinase regulate the protein kinase B in Fc epsilon RI signaling in RBL 2H3 mast cells. J Immunol. 2001;166:1627-1634.
-
(2001)
J Immunol
, vol.166
, pp. 1627-1634
-
-
Djouder, N.1
Schmidt, G.2
Frings, M.3
Cavalie, A.4
Thelen, M.5
Aktories, K.6
-
39
-
-
0029039957
-
Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway
-
Karnitz LM, Burns LA, Sutor SL, Blenis J, Abraham RT. Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway. Mol Cell Biol. 1995;15:3049-3057.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3049-3057
-
-
Karnitz, L.M.1
Burns, L.A.2
Sutor, S.L.3
Blenis, J.4
Abraham, R.T.5
-
40
-
-
0033000334
-
p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes
-
Brennan P, Babbage JW, Thomas G, Cantrell D. p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes. Mol Cell Biol. 1999;19:4729-4738.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4729-4738
-
-
Brennan, P.1
Babbage, J.W.2
Thomas, G.3
Cantrell, D.4
-
41
-
-
0033566806
-
Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation
-
Colucci F, Turner M, Schweighoffer E, et al. Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation. J Immunol. 1999;163:1769-1774.
-
(1999)
J Immunol
, vol.163
, pp. 1769-1774
-
-
Colucci, F.1
Turner, M.2
Schweighoffer, E.3
-
42
-
-
0036194976
-
Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases
-
Colucci F, Schweighoffer E, Tomasello E, et al. Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases. Nat Immunol. 2002;3:288-294.
-
(2002)
Nat Immunol
, vol.3
, pp. 288-294
-
-
Colucci, F.1
Schweighoffer, E.2
Tomasello, E.3
-
43
-
-
0030716243
-
Generation of lytic natural killer 1.1+, Ly-49-cells from multipotential murine bone marrow progenitors in a stroma-free culture: Definition of cytokine requirements and developmental intermediates
-
Williams NS, Moore TA, Schatzle JD, et al. Generation of lytic natural killer 1.1+, Ly-49-cells from multipotential murine bone marrow progenitors in a stroma-free culture: Definition of cytokine requirements and developmental intermediates. J Exp Med. 1997;186:1609-1614.
-
(1997)
J Exp Med
, vol.186
, pp. 1609-1614
-
-
Williams, N.S.1
Moore, T.A.2
Schatzle, J.D.3
-
44
-
-
0026441372
-
Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lymphocytes, and NK cells
-
Perussia B, Chan SH, D'Andrea A, et al. Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lymphocytes, and NK cells. J Immunol. 1992;149:3495-3502.
-
(1992)
J Immunol
, vol.149
, pp. 3495-3502
-
-
Perussia, B.1
Chan, S.H.2
D'Andrea, A.3
-
46
-
-
0032533237
-
Flt3 ligand promotes the generation of a distinct CD34(+) human natural killer cell progenitor that responds to interleukin-15
-
Yu H, Fehniger TA, Fuchshuber P, et al. Flt3 ligand promotes the generation of a distinct CD34(+) human natural killer cell progenitor that responds to interleukin-15. Blood. 1998;92:3647-3657.
-
(1998)
Blood
, vol.92
, pp. 3647-3657
-
-
Yu, H.1
Fehniger, T.A.2
Fuchshuber, P.3
-
47
-
-
0031927280
-
Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc
-
Walk SF, March ME, Ravichandran KS. Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc. Eur J Immunol. 1998;28:2265-2275.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2265-2275
-
-
Walk, S.F.1
March, M.E.2
Ravichandran, K.S.3
-
48
-
-
0033826512
-
New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
-
Gu H, Maeda H, Moon JJ, et al. New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway. Mol Cell Biol. 2000;20:7109-7120.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7109-7120
-
-
Gu, H.1
Maeda, H.2
Moon, J.J.3
-
49
-
-
0034282897
-
The docking molecule gab2 is induced by lymphocyte activation and is involved in signaling by interleukin-2 and interleukin-15 but not other common gamma chain-using cytokines
-
Gadina M, Sudarshan C, Visconti R, et al. The docking molecule gab2 is induced by lymphocyte activation and is involved in signaling by interleukin-2 and interleukin-15 but not other common gamma chain-using cytokines. J Biol Chem. 2000;275:26959-26966.
-
(2000)
J Biol Chem
, vol.275
, pp. 26959-26966
-
-
Gadina, M.1
Sudarshan, C.2
Visconti, R.3
-
50
-
-
0031205192
-
Involvement of protein tyrosine kinase p72syk and phosphatidylinositol 3-kinase in CD2-mediated granular exocytosis in the natural killer cell line, NK3.3
-
Umehara H, Huang JY, Kono T, et al. Involvement of protein tyrosine kinase p72syk and phosphatidylinositol 3-kinase in CD2-mediated granular exocytosis in the natural killer cell line, NK3.3. J Immunol. 1997;159:1200-1207.
-
(1997)
J Immunol
, vol.159
, pp. 1200-1207
-
-
Umehara, H.1
Huang, J.Y.2
Kono, T.3
-
51
-
-
0031797243
-
Functional cooperation of the interleukin-2 receptor beta chain and Jakl in phosphatidylinositol 3-kinase recruitment and phosphorylation
-
Migone TS, Rodig S, RodigS, Cacalano NA, Berg M, Schreiber RD, Leonard WJ. Functional cooperation of the interleukin-2 receptor beta chain and Jakl in phosphatidylinositol 3-kinase recruitment and phosphorylation. Mol Cell Biol. 1998;18:6416-6422.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6416-6422
-
-
Migone, T.S.1
Rodig, S.2
Rodig, S.3
Cacalano, N.A.4
Berg, M.5
Schreiber, R.D.6
Leonard, W.J.7
-
52
-
-
0034507903
-
Bcap: The tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation
-
Okada T, Maeda A, Iwamatsu A, Gotoh K, Kurosaki T. BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation. Immunity. 2000;13:817-827.
-
(2000)
Immunity
, vol.13
, pp. 817-827
-
-
Okada, T.1
Maeda, A.2
Iwamatsu, A.3
Gotoh, K.4
Kurosaki, T.5
-
53
-
-
0031815797
-
Phosphorylation of the Grb2- and phosphatidylinositol 3-kinase p85-binding p36/38 by Syk in Lck-negative T cells
-
von Willebrand M, Williams S, Tailor P, Mustelin T. Phosphorylation of the Grb2- and phosphatidylinositol 3-kinase p85-binding p36/38 by Syk in Lck-negative T cells. Cell Signal. 1998;10:407-413.
-
(1998)
Cell Signal
, vol.10
, pp. 407-413
-
-
Von Willebrand, M.1
Williams, S.2
Tailor, P.3
Mustelin, T.4
-
54
-
-
0031913246
-
Mechanism of activation and function of protein kinase B
-
Alessi OR, Cohen P. Mechanism of activation and function of protein kinase B. Curr Opin Genet Dev. 1998;8:55-62.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 55-62
-
-
Alessi, O.R.1
Cohen, P.2
-
55
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature. 1995;376:599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
56
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke TF, Yang SI, Chan TO, et al. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell. 1995;81:727-736.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
-
57
-
-
0033535964
-
The tyrosine kinases Syk and Lyn exert opposing effects on the activation of protein kinase Akt/PKB in B lymphocytes
-
Li HL, Davis WW, Whiteman EL, Birnbaum MJ, Pure E. The tyrosine kinases Syk and Lyn exert opposing effects on the activation of protein kinase Akt/PKB in B lymphocytes. Proc Natl Acad Sci U S A. 1999;96:6890-6895.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 6890-6895
-
-
Li, H.L.1
Davis, W.W.2
Whiteman, E.L.3
Birnbaum, M.J.4
Pure, E.5
-
58
-
-
0030968580
-
Rho GTPases and signaling networks
-
Van Aelst L, D'Souza-Schorey C. Rho GTPases and signaling networks. Genes Dev. 1997;11:2295-2322.
-
(1997)
Genes Dev
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
59
-
-
0034213327
-
Rho GTPases and their effector proteins
-
Bishop AL, Hall A. Rho GTPases and their effector proteins. Biochem J. 2000;348 Pt 2:241-255.
-
(2000)
Biochem J
, vol.348
, Issue.PART 2
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
60
-
-
0033912699
-
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase
-
Genot EM, Arrieumerlou C, Ku G, Burgering BM, Weiss A, Kramer IM. The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase. Mol Cell Biol. 2000;20:5469-5478.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5469-5478
-
-
Genot, E.M.1
Arrieumerlou, C.2
Ku, G.3
Burgering, B.M.4
Weiss, A.5
Kramer, I.M.6
-
61
-
-
0030293886
-
Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways
-
Reif K, Nobes CD, Thomas G, Hall A, Cantrell DA. Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways. Curr Biol. 1996;6:1445-1455.
-
(1996)
Curr Biol
, vol.6
, pp. 1445-1455
-
-
Reif, K.1
Nobes, C.D.2
Thomas, G.3
Hall, A.4
Cantrell, D.A.5
-
62
-
-
0343183328
-
Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
-
Liliental J, Moon SY, Lesche R, et al. Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases. Curr Biol. 2000;10:401-404.
-
(2000)
Curr Biol
, vol.10
, pp. 401-404
-
-
Liliental, J.1
Moon, S.Y.2
Lesche, R.3
-
63
-
-
0033539945
-
PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein
-
Paramio JM, Navarro M, Segrelles C, GomezCasero E, Jorcano JL. PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein. Oncogene. 1999;18:7462-7468.
-
(1999)
Oncogene
, vol.18
, pp. 7462-7468
-
-
Paramio, J.M.1
Navarro, M.2
Segrelles, C.3
GomezCasero, E.4
Jorcano, J.L.5
-
64
-
-
0036533651
-
Syk regulation of phosphoinositide 3-kinase-dependent NK cell function
-
Jiang K, Zhong B, Gilvary DL, et al. Syk regulation of phosphoinositide 3-kinase-dependent NK cell function. J Immunol. 2002;168:3155-3164.
-
(2002)
J Immunol
, vol.168
, pp. 3155-3164
-
-
Jiang, K.1
Zhong, B.2
Gilvary, D.L.3
-
65
-
-
0036305341
-
A view to a kill: Signals triggering cytotoxicity
-
Djeu JY, Jiang K, Wei S. A view to a kill: Signals triggering cytotoxicity. Clin Cancer Res. 2002;8:636-640.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 636-640
-
-
Djeu, J.Y.1
Jiang, K.2
Wei, S.3
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