A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds

Journal of Medicinal Chemistry

Volumn 41, Issue 21, 1998, Pages 3994-4000

  Van Muijlwijk Koezen, Jacqueline E ^a,c   Timmerman, Henk ^a   Link, Regina ^b   Van der Goot, Henk ^a   Uzerman, Adriaan P ^b  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHOXY N [2 (2 PYRIDINYL)QUINAZOLIN 4 YL]BENZAMIDE; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; BENZAMIDE DERIVATIVE; ISOQUINOLINE DERIVATIVE; N [2 (2 PYRIDINYL)ISOQUINOLIN 4 YL]BENZAMIDE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG; VUF 8504; VUF 8507;

ARTICLE; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; LIGAND BINDING; NONHUMAN; RAT; RECEPTOR AFFINITY;

ANIMALS; CELL LINE; CEREBRAL CORTEX; HUMANS; ISOMERISM; ISOQUINOLINES; MOLECULAR CONFORMATION; PYRIDINES; QUINAZOLINES; RADIOLIGAND ASSAY; RATS; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032497636     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980037i     Document Type: Article

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