Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5

Neuron

Volumn 20, Issue 1, 1998, Pages 143-151

  Gereau IV, Robert W ^a   Heinemann, Stephen F ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; METABOTROPIC RECEPTOR; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; DESENSITIZATION; ENZYME ACTIVITY; NERVE CELL PLASTICITY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PYRAMIDAL NERVE CELL; RECEPTOR BINDING; XENOPUS;

EID: 0031932286     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80442-0     Document Type: Article

References (27)

1. 2+ signal transduction. J. Biol. Chem. 267, 13361-13368.
2. Alaluf, S., Mulvihill, E.R., and Mcllhinney, A.J. (1995). Rapid agonist mediated phosphorylation of the metabotropic glutamate receptor 1a by protein kinase C in permanently transfected BHK cells. FEBS Lett. 367, 301-305.
3. Aniksztejn, L., Bregestovski, P., and Ben-Ari, Y. (1991). Selective activation of quisqualate metabotropic receptors potentiates NMDA but not AMPA responses. Eur. J. Pharmacol. 205, 327-328.
4. Aronica, E., Dell'Albani, P., Condorelli, D.F., Nicoletti, F., Hack, N., and Balazas, R. (1994). Mechanisms underlying developmental changes in the expression of metabotropic glutamate receptors in cultured cerebellar granule cells: homologous desensitization and interactive effects involving N-methyl-D-aspartate receptors. Mol. Pharmacol. 44, 981-989.
5. Brakeman, P.R., Lanahan, A.A., O'Brien, R., Roche, K., Barnes, C.A., Huganir, R.L., and Worley, P.F. (1997). Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386, 284-288.
6. Catania, M.V., Aronica, E., Sortino, M.A., Canonico, P.L., and Nicoletti, F. (1991). Desensitization of metabotropic glutamate receptors in neuronal cultures. J. Neurochem. 56, 1329-1335.
7. Conn, P.J., and Pin, J.-P. (1997). Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 37, 205-237.
8. Desai, M.A., Smith, T.S., and Conn, P.J. (1991). Excitatory effects of ACPD receptor activation in the hippocampus are mediated by direct effects on pyramidal cells and blockade of synaptic inhibition. J. Neurophysiol. 66, 40-52.
9. Desai, M.A., Burnett, J.P., Mayne, N.G., and Schoepp, D.D. (1995). Cloning and expression of a human metabotropic glutamate receptor 1a: enhanced coupling on co-transfection with a glutamate transporter. Mol. Pharmacol. 48, 648-657.
10. Desai, M.A., Burnett, J.P., Mayne, N.G., and Schoepp, D.D. (1996). Pharmacological characterization of desensitization in a human mGluR1a-expressing non-neuronal cell line co-transfected with a glutamate transporter. Br. J. Pharmacol. 118, 1558-1564.
11. Gereau, R.W., and Conn, P.J. (1995a). Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1. J. Neurosci. 15, 6879-6889.
12. Gereau, R.W., and Conn, P.J. (1995b). Roles of specific metabotropic glutamate receptors in regulating hippocampal CA1 pyramidal cell excitability. J. Neurophysiol. 74, 122-129.
13. Glaum, S.R., Slater, N.T., Rossi, D.J., and Miller, R.J. (1992). Role of metabotropic glutamate (ACPD) receptors at the parallel fiber-Purkinje cell synapse. J. Neurophysiol. 68, 1453-1462.
14. Godfrey, P.P., and Taghavi, Z. (1990). The effect of non-NMDA antagonists and phorbol esters on excitatory amino acid stimulated inositol phosphate formation in rat cerebral cortex. Neurochem. Int. 16, 65-72.
15. Gomeza, J., Joly, C., Kuhn, R., Knöpfel, T., Bockaert, J., and Pin, J.-P. (1996). The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins. J. Biol. Chem. 271, 2199-2205.
16. Guerineau, N.C., Bossu, J.-L., Gahwiler, B.H., and Gerber, U. (1997). G-protein-mediated desensitization of metabotropic glutamatergic and muscarinic responses in CA3 cells in rat hippocampus. J. Physiol. 500, 487-496.
17. Hausdorff, W.P., Caron, M.G., and Lefkowitz, R.J. (1990). Turning off the signal: desensitization of b-adrenergic receptor function. FASEB J. 4, 2881-2889.
18. Herrero, I., Miras-Portugal, T., and Sanchez-Prieto, J. (1994). Rapid desensitization of the metabotropic glutamate receptor that facilitates glutamate release in rat cerebrocortical nerve terminals. Eur. J. Neurosci. 6, 115-120.
19. Hu, G.-Y., and Storm, J.F. (1992). Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons. Brain Res. 568, 339-344.
20. Kawabata, S., Tsutsumi, R., Kohara, A., Yamaguchi, T., Nakanishi, S., and Okada, M. (1996). Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors. Nature 383, 89-92.
21. Lefkowitz, R.J. (1993). G protein-coupled receptor kinases. Cell 74, 409-412.
22. Lu, Y.-M., Jia, Z., Janus, C., Henderson, J.T., Gerlai, R., Wojtowicz, J.M., and Roder, J.C. (1997). Mice lacking metabotropic glutamate receptors show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J. Neurosci. 17, 5196-5205.
23. Minakami, R., Katsuki, F., Yamamoto, T., Nakamura, K., and Sugiyama, H. (1993). Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5. Biochem. Biophys. Res. Commun. 199, 1136-1143.
24. Pearson, R.B., and Kemp, B.E. (1991). Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations. Meth. Enzymol. 200, 62-81.
25. Schoepp, D.D., and Johnson, B.G. (1988). Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C. Biochem. Pharmacol. 37, 4299-4305.
26. Thomsen, C., Mulvihill, E.R., Haldeman, B., Pickering, D.S., Hampson, D.R., and Suzdak, P.D. (1993). A pharmacological characterization of the mGluR1a subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line. Brain. Res. 619, 22-28.
27. Trussell, L.O., Zhang, S., and Raman, I.M. (1993). Desensitization of AMPA receptors upon multiquantal neurotransmitter release. Neuron 10, 1185-1196.