Metabotropic glutamate receptors activate G-protein-coupled inwardly rectifying potassium channels in Xenopus oocytes

Journal of Neuroscience

Volumn 16, Issue 19, 1996, Pages 5979-5985

  Saugstad, Julie A ^a   Segerson, Thomas P ^a   Westbrook, Gary L ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

G protein coupled inwardly rectifying potassium channel; glutamate receptors; metabotropic glutamate receptor; microdomains; synaptic inhibition; synaptic modulation; Xenopus oocyte

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; METABOTROPIC RECEPTOR; PHOSPHOLIPASE C; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHLORIDE CURRENT; ELECTROPHYSIOLOGY; GENE EXPRESSION; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SYNAPTIC INHIBITION; XENOPUS LAEVIS;

EID: 0029788280     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-19-05979.1996     Document Type: Article

References (66)

1. Alder J, Lu B, Valtorta F, Greengard P, Poo M-M (1992) Calcium-dependent transmitter secretion reconstituted in Xenopus oocytes: requirement for synaptophysin. Science 257:657-661.
2. B receptors to the same channels in hippocampus. Science 234:1261-1265.
3. Aramori I, Nakanishi S (1992) Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR1, in transfected CHO cells. Neuron 8:757-765.
4. Bates MD, Senogles SE, Bunzow JR, Liggett SB, Civelli O, Caron MG (1991) Regulation of responsiveness at D2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization. Mol Pharmacol 39:55-63.
5. Baude A, Nusser Z, Roberts JDB, Mulvihill E, McIlhinney RAJ, Somogyi P (1993) The metabotropic glutamate receptor (mGluR1a) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 11:771-787.
6. Birnbaumer L (1992) Receptor-to-effector signaling through G proteins: roles for βγ dimers as well as a subunits. Cell 71:1069-1072.
7. Bolshakov VY, Svetlana AG, Katchman AN, Magazanik LG (1993) Activation of a common potassium channel in molluscan neurones by glutamate, dopamine, and muscarinic agonist. J Physiol (Lond) 468:11-33.
8. Bradley SR, Levey AI, Hersch SM, Conn PJ (1996) Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies. J Neurosci 16:2044-2056.
9. Clapham DE (1994) Direct G-protein activation of ion channels? Annu Rev Neurosci 17:441-464.
10. Dascal N, Ifune C, Hopkins R, Snutch TP, Lubbert H, Davidson N, Simon MI, Lester HA (1986) Involvement of a GTP-binding protein in mediation of serotonin and acetylcholine responses in Xenopus oocytes injected with rat brain messenger RNA. Brain Res 387:201-209.
11. + channel: expression cloning and molecular properties. Proc Natl Acad Sci USA 90:10235-10239.
12. Dascal N, Lim NF, Schreibmayer W, Wang W, Davidson N, Lester HA (1993b) Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes. Proc Natl Acad Sci USA 90:6596-6600.
13. s couples thyrotropin-releasing hormone receptors expressed in Xenopus oocytes to phospholipase C. J Biol Chem 270:3554-3559.
14. Doupnik GA, Davidson N, Lester HA (1995) The inward rectifier potassium channel family. Curr Opin Neurobiol 5:268-277.
15. Gereau IV RW, Conn PJ (1995) Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1. J Neurosci 15:6879-6889.
16. KAch currents in oocytes. Neuron 16:423-429.
17. Hille B (1992) G protein-coupled mechanisms and nervous signaling. Neuron 9:187-195.
18. Hirano AA, MacLeish PR (1991) Glutamate and 2-amino-4-phosphonobutyrate evoke an increase in potassium conductance in retinal bipolar cells. Proc Natl Acad Sci USA 88:805-809.
19. Houamed KM, Kuijper JL, Gilbert TL, Haldeman BA, O'Hara PJ, Mulvihill ER, Almers W, Hagen FS (1991) Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brain. Science 252:1318-1321.
20. Ikeda SR, Lovinger DM, McCool BA, Lewis DL (1995) Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: subtype-specific coupling to ion channels. Neuron 14:1029-1038.
21. Johnson SW, Seutin V, North RA (1992) Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump. Science 258:665-667.
22. Jones SVP (1996) Modulation of the inwardly rectifying potassium channel IRK1 by the m1 muscarinic receptor. Mol Pharmacol 49:662-667.
23. Kinzie JM, Saugstad JA, Westbrook GL, Segerson TP (1995) Distribution of metabotropic glutamate receptor 7 mRNA in the developing and adult rat brain. Neuroscience 69:167-176.
24. Kondo H, Toyoda J-I (1980) Dual effect of glutamate and aspartate on the on-center bipolar cell in the carp retina. Brain Res 199:240-243.
25. +-channel proteins. Nature 374:135-141.
26. Kubo Y, Reuveny E, Slesinger PA, Jan YN, Jan LY (1993) Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature 364:802-806.
27. 2 receptors to increase potassium conductance in neurones of the rat substantia nigra zona compacta. J Physiol (Lond) 392:397-416.
28. Lester RAJ, Jahr CE (1990) Quisqualate receptor-mediated depression of calcium currents in hippocampal neurons. Neuron 4:741-749.
29. 2+ currents in rat anterior pituitary cells. Neuron 8:455-463.
30. + channel in heart. Nature 325:536-538.
31. Martin LJ, Blackstone GD, Huganir RL, Price DL (1992) Cellular localization of a metabotropic glutamate receptor in rat brain. Neuron 9:259-270.
32. Masu M, Tanabe Y, Tsuchida K, Shigemoto R, Nakanishi S (1991) Sequence and expression of a metabotropic glutamate receptor. Nature 349:760-765.
33. Mayer ML, Westbrook GL (1987) The physiology of excitatory amino acids in the vertebrate central nervous system. Prog Neurobiol 28:197-276.
34. Melton DA, Krieg PA, Rebagliati MR, Maniatis T, Zinn K, Green MR (1984) Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res 12:7035-7056.
35. Nawy S, Copenhagen DR (1990) Intracellular cesium separates two glutamate conductances in retinal bipolar cells of goldfish. Vision Res 30:967-972.
36. Neubig RR (1994) Membrane organization in G protein mechanisms. FASEB J 8:939-946.
37. Nicoll RA, Alger BE (1981) Synaptic excitation may activate a calcium-dependent potassium conductance in hippocampal pyramidal cells. Science 212:957-959.
38. Nomura A, Shigemoto R, Nakamura Y, Okamoto N, Mizuno N, Nakanishi S (1994) Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells. Cell 77:361-369.
39. North RA, Williams JT (1985) On the potassium conductance increased by opioids in rat locus cocruleus neurones. J Physiol (Lond) 364:265-280.
40. Ohishi H, Ogawa-Meguro R, Shigemoto R, Kaneko T, Nakanishi S, Mizuno N (1994) Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex. Neuron 13:55-66.
41. Okamoto N, Hori S, Akazawa C, Hayashi Y, Shigemoto R, Mizuno N, Nakanishi S (1994) Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J Biol Chem 269:1231-1236.
42. Onate A, Herrera L, Antonelli M, Birnbaumer L, Olate J (1992) Xenopus laevis oocyte Ga subunit mRNAs: detection and quantitation during oogenesis and early embryogenesis by competitive reverse PCR. FEBS Lett 313:213-219.
43. Pin J-P, Bockaert J (1995) Get receptive to metabotropic glutamate receptors. Curr Opin Neurobiol 5:342-349.
44. Pin J-P, Duvoisin R (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34:1-26.
45. Pin J-P, Joly C, Heinemann SF, Bockaert J (1994) Domains involved in the specificity of G-protein activation in phospholipase C-coupled metabotropic glutamate receptors. EMBO J 13:342-348.
46. + channel proteins (GIRK1) are present in the soma and dendrites as well as in nerve terminals of specific neurons in the brain. J Neurosci 16:1990-2001.
47. Pritchett DB, Bach AW, Wozny M, Taleb O, Dal Toso R, Shih JC, Seeburg PH (1988) Structure and functional expression of cloned rat serotonin 5HT-2 receptor. EMBO J 7:4135-4140.
48. Quick MW, Simon MI, Davidson N, Lester HA, Aragay AM (1994) Differential coupling of G protein a subunits to seven-helix receptors expressed in Xenopus oocytes. J Biol Chem 269:30164-30172.
49. Ransom BR, Barker JL, Nelson PG (1975) Two mechanisms for post-stimulus hyperpolarisations in cultured mammalian neurones. Nature 256:424-425.
50. Romano C, Sesma MA, McDonald CT, O'Malley K, van den Pol AN, Olney JW (1995) Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. J Comp Neurol 355:455-469.
51. Rothe T, Bigl V, Grantyn R (1994) Potentiating and depressant effects of metabotropic glutamate receptor agonists on high-voltage-activated calcium currents in cultured retinal ganglion neurons from postnatal mice. Pflügers Arch 426:161-170.
52. Sahara Y, Westbrook GL (1993) Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons. J Neurosci 13:3041-3050.
53. Saugstad JA, Kinzie JM, Mulvihill EM, Segerson TP, Westbrook GL (1994) Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors. Mol Pharmacol 45:367-372.
54. Saugstad JA, Segerson TP, Westbrook GL (1995a) Modulation of ion channels and synaptic transmission by metabotropic glutamate receptors. In: Excitatory amino acids and synaptic transmission, 2nd Ed. (Wheal H, Thomson A, eds), pp 77-88. New York: Academic.
55. Saugstad JA, Segerson TP, Westbrook GL (1995b) L-2-Amino-3-phosphonopropionic acid competitively antagonizes metabotropic glutamate receptors 1a and 5 in Xenopus oocytes. Eur J Pharmacol 289:395-397.
56. 2+ channels involved? Neuropharmacology 34:1549-1557.
57. + channel by G protein alpha subunits. Nature 380:624-627.
58. + channel (GIRK) expressed in Xenopus oocytes. Soc Neurosci Abstr 21:524.10.
59. Shirasaki T, Harata N, Akaike N (1994) Metabotropic glutamate response in acutely dissociated hippocampal CA1 pyramidal neurons of the rat. J Physiol (Lond) 475:439-453.
60. Sladeczek F, Pin J-P, Récasens M, Bockaert J, Weiss S (1985) Glutamate stimulates inositol phosphate formation in striatal neurones. Nature 317:717-719.
61. Swartz KJ, Bean BP (1992) Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor. J Neurosci 12:4358-4371.
62. 2+ channels and synaptic transmission. Nature 361:165-168.
63. Tanabe Y, Masu M, Ishii T, Shigemoto R, Nakanishi S (1992) A family of metabotropic glutamate receptors. Neuron 8:169-179.
64. Trombley PQ, Westbrook GL (1992) L-AP4 inhibits calcium currents and synaptic transmission via a G-protein-coupled glutamate receptor. J Neurosci 12:2043-2050.
65. Wickman KD, Iñlguez-Lluhl JA, Davenport PA, Taussig R, Krapivinsky GB, Linder ME, Gilman AG, Clapham DE (1994) Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel. Nature 368:255-257.
66. Zorumski CF, Thio LL, Clark GD, Clifford DB (1989) Calcium influx through N-methyl-D-aspartate channels activates a potassium current in postnatal rat hippocampal neurons. Neurosci Lett 99:293-299.