L-764406 is a partial agonist of human peroxisome proliferator-activated receptor γ. The role of Cys313 in ligand binding

Journal of Biological Chemistry

Volumn 274, Issue 12, 1999, Pages 7913-7922

  Elbrecht, Alex ^a   Chen, Yuli ^a   Adams, Alan ^a   Berger, Joel ^a   Griffin, Patrick ^a   Klatt, Tracey ^a   Zhang, Bei ^a   Menke, John ^a   Zhou, Gaochao ^a   Smith, Roy G ^a   Moller, David E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTILIPEMIC AGENT; CYSTEINE; FIBRIC ACID DERIVATIVE; HYBRID PROTEIN; L 273422; L 763780; L 764406; L 764475; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RECEPTOR SUBTYPE; ROSIGLITAZONE; THIAZOLIDINE DERIVATIVE; TROGLITAZONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; COVALENT BOND; DRUG BINDING SITE; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN QUATERNARY STRUCTURE; RECEPTOR AFFINITY; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COS CELLS; CYSTEINE; HUMANS; KINETICS; LIGANDS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; QUINOXALINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0033583241     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.12.7913     Document Type: Article

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