Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes

Journal of Biological Chemistry

Volumn 277, Issue 48, 2002, Pages 45984-45991

  Pahan, Kalipada ^a   Jana, Malabendu ^a   Liu, Xiaojuan ^a   Taylor, Bradley S ^b   Wood, Charles ^c   Fischer, Susan M ^d  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA   (United States)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; DRUG PRODUCTS; ENZYMES; LIPIDS; NITROGEN COMPOUNDS;

TRANSCRIPTION FACTORS;

BIOCHEMISTRY;

ARGINASE; CCAAT ENHANCER BINDING PROTEIN BETA; GAMMA INTERFERON; GEMFIBROZIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1BETA; LUCIFERASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RNA; STAT PROTEIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CELL VIABILITY; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG USE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; NEUROLOGIC DISEASE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE;

ASTROCYTES; BLOTTING, WESTERN; CELL LINE; ENZYME INDUCTION; GEMFIBROZIL; HUMANS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS;

EID: 0037195866     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M200250200     Document Type: Article

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