Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells

Journal of Biological Chemistry

Volumn 274, Issue 11, 1999, Pages 7528-7536

  Panan, Kalipada ^a   Raymond, John R ^a   Singh, Inderjit ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ARTICLE; ASTROCYTE; DEMYELINATING DISEASE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; GLIA CELL; NERVE DEGENERATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DNA BINDING; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; BASE SEQUENCE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CHROMONES; DNA PRIMERS; ENZYME ACTIVATION; ENZYME INHIBITORS; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MORPHOLINES; NEUROGLIA; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RATS;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0033548627     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.11.7528     Document Type: Article

References (41)

1. Jaffrey, S. R., and Snyder, S. H. (1995) Anna. Rev. Cell Dev. Biol. 11, 417-440
2. Nathan, C. (1992) FASEB J. 6, 3051-3064
3. Mitrovic, B., Ignarro, L. J., Montestruque, S., Smoll, A., and Merril, J. E. (1994) Neuroscience 61, 575-585
4. Bo, L., Dawson, T. M., Wesselingh, S., Mork, S., Choi, S., Kong, P. A., Hanley, D., and Trapp, B. D. (1994) Ann. Neurol. 36, 778-786
5. Merrill, J. E., Ignarro, L. J., Sherman, M. P., Melinek, J., and Lane, T. E. (1993) J. Immunol. 151, 2132-2141
6. Koprowski, H., Zheng, Y. M., Heber-Katz, E., Fraser, N., Rorke, L., Fu, Z. F., Hanlon, C., and Dietzshold, B. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3024-3027
7. Cross, A. H., Misko, T. P., Lin, R. F., Hickey, W. F., Trotter, J. L., and Tilton, R. G. (1994) J. Clin. Invest. 93, 2684-2690
8. Hooper, D. C., Bagsra, O., Marini, J. C., Zborek, A., Ohnishi, S. T., Kean, R., Champion, J. M., Sarker, A. B., Bobroski, L., Farber, J. L., Akaike, T., Maeda, H., and Koprowski, H. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2528-2533
9. Hu, S. X., Sheng, W. S., Peterson, P. K., and Chao, C. C. (1995) Glia 15, 491-494
10. Galea, E., Feinstein, D. L., and Reis, D. J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 10945-10949
11. Pahan, K., Sheikh, F. G., Namboodiri, A. M. S., and Singh, I. (1997) J. Clin. Invest. 100, 2671-2679
12. Pahan, K., Namboodiri, A. M. S., Sheikh, F. G., Smith, B. T., and Singh, I. (1997) J. Biol. Chem. 272, 7786-7791
13. Pahan, K., Sheikh, F. G., Namboodiri, A. M. S., and Singh, I. (1998) Free Radical Biol. Med. 24, 39-48
14. Xie, Q.-W., Kashiwabara, Y., and Nathan, C. (1994) J. Biol. Chem. 269, 4705-4708
15. Kwon, G., Corbett, J. A., Rodi, C. P., Sullivan, P., and McDaniel, M. L. (1995) Endocrinology 136, 4790-4795
16. Feinstein, D. L., Galea, E., Cermak, J., Chugh, P., Lyandvert, L., and Reis, D. J. (1994) J. Neurochem. 62, 811-814
17. Nishiya, T., Uehara, T., and Nomura, Y. (1995) FEBS Lett. 371, 333-336
18. Pahan, K., Sheikh. F. G., Khan, M., Namboodiri, A. M. S., and Singh, I. (1998) J. Biol. Chem. 273, 2591-2600
19. McCarthy, K., and DeVellis, J. (1980) J. Cell Biol. 85, 890-902
20. Feinstein, D. L., Galea, E., Roberts, S., Berquist, H., Wang, H., and Reis, D. J. (1994) J. Neurochem. 62, 315-321
21. Geller, D. A., Lowenstein, C. J., Shapiro, R. A., Nussler, A. K., DiSilvio, M., Wang, S. C., Nakayama, D. K., Simmons, R. L., Snyder, S. H., and Billiar, T. R. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3491-3495
22. Eberhardt, W., Kunz, D., Hummel, R., and Pfeilschifler, J. (1996) Biochem. Biophys Res. Commun. 223, 752-756
23. Hara, K., Yonezawa, K., Sakaue, H., Ando, A., Kotani, K, Kitamura, T., Kitamura, Y., Ueda, H., Stephens, L., Jackson, R., Hawkin, P. T., Dhand, R., Clark, A. E., Holman, G. D., Waterfied, M. D., and Kasuga, M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7415-7419
24. Ward, S. G., Reif, K., Ley, S., Fry, M. J., Waterfield, M. D., and Cantrell, D. A. (1992) J. Biol. Chem. 267, 23862-23869
25. Dignam, D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
26. Nguyen, V. T., Morange, M., and Bensaude, O. (1988) Anal. Biochem. 171, 404-408
27. Pahan, K., Sheikh, F. G., Namboodiri, A. M. S., and Singh, I. (1998) J. Biol. Chem. 273, 12219-12226
28. Dobashi, K., Pahan, K., Chahal, A., and Singh, I. (1997) J. Neurochem. 68, 1896-1903
29. Teruel, T., Valverde, A. M., Navarro, P., Benito, M., and Lorenzo, M. (1998) J. Cell. Physiol. 176, 99-109
30. Okada, T., Kawano, Y., Sakakakibara, T., Hazeki, M., and Ui, M. (1994) J. Biol. Chem. 269, 3568-3573
31. Powis, G., Bonjouklian, R., Berggren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., Grindey, G., and Vlahos, C. J. (1994) Cancer Res. 54, 2419-2423
32. Liu, Q., Schacher, D., Hurth, C., Freund, G. G., Dantzer, R., and Kelly, K. W. (1997) J. Immunol. 159, 829-837
33. Minshall, C., Arkins, S., Freund, G. G., and Kelly, K. W. (1996) J. Immunol. 156, 939-947
34. Leist, M., Fava, E., Montecucco, C., and Nicotera, P. (1997) Eur. J. Neurosci. 9, 1488-1498
35. Xie, K., Wang, Y., Huang, S., Xu, L., Bielenberg, D., Salas, T., McConkey, D. J., Jiang, W., and Fidler, I. J. (1997) Oncogene 15, 771-779
36. Stefanova, I., Corcoran, M. L., Horak, E. M., Wahl, L. M., Bolen, J. B., and Horak, I. D. (1993) J. Biol. Chem. 268, 20725-20728
37. Salkowski, C. A., Detore, G., McNally, R., van Rooijen, N., and Vogel, S. N. (1997) J. Immunol. 158, 905-912
38. Beg, A. A., Ruben, S. M., Scheinman, R. I., Haskil, S., Rosen, C. A., and Baldwin, A. S., Jr. (1992) Genes Dev. 6, 1899-1913
39. Sun, S.-C., Ganchi, P. A , Ballard, D. W., and Greene, W. C. (1993) Science 259, 1912-1915
40. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G., and Siebenlist, U. (1995) Science 267, 1485-1488
41. Ghoda, L., Lin, X., and Greene, W. C. (1997) J. Biol. Chem. 272, 21281-21288