메뉴 건너뛰기




Volumn 26, Issue 7, 1996, Pages 723-753

Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: Rationalization of CYP1A substrate specificity in terms of active site amino acid residues

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINOTOLUENE; 2,5 DIAMINOTOLUENE; 7 ETHOXYCOUMARIN; 7,8 DIHYDROXYBENZO[A]PYRENE; ACETANILIDE; AFLATOXIN B1; AMINO ACID; BENZO[A]PYRENE; CAFFEINE; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; ESTRADIOL; ETHOXYRESORUFIN; PHENACETIN; UNCLASSIFIED DRUG;

EID: 0030036211     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.3109/00498259609046745     Document Type: Article
Times cited : (86)

References (101)
  • 1
    • 0027337609 scopus 로고
    • Aflatoxin B, induces the transversion of G-T in codon 249 of the p53 tumour suppressor gene in human hepatocytes
    • AGUILAR, F., HUSSAIN, P., and CERUTTI, P., 1993, Aflatoxin B, induces the transversion of G-T in codon 249 of the p53 tumour suppressor gene in human hepatocytes. Proceedings of the National Academy of Sciences, USA, 90, 8546-8590.
    • (1993) Proceedings of the National Academy of Sciences, USA , vol.90 , pp. 8546-8590
    • Aguilar, F.1    Hussain, P.2    Cerutti, P.3
  • 4
    • 0026646696 scopus 로고
    • Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes
    • BERTHOU, F., DREANO, Y., JACQZ-AIGRAIN, E., GUILLOIS, B., and BEAUNE, P. H., 1992, Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes. Xenobiotica, 22, 671-680.
    • (1992) Xenobiotica , vol.22 , pp. 671-680
    • Berthou, F.1    Dreano, Y.2    Jacqz-Aigrain, E.3    Guillois, B.4    Beaune, P.H.5
  • 5
    • 0028853940 scopus 로고
    • Species variation in the metabolism of 15,16-dihydro-11-methylcyclopenta[a]phenanthren-17-one to its 3,4-dihydrodiol, the proximate carcinogen
    • BOYD, G. W., COOMBS, M. M., IOANNIDES, C., LEWIS, D. F. V., SNELLING, J., and TSAKALOF, A., 1995, Species variation in the metabolism of 15,16-dihydro-11-methylcyclopenta[a]phenanthren-17-one to its 3,4-dihydrodiol, the proximate carcinogen. Carcinogenesis, 16, 2351-2355.
    • (1995) Carcinogenesis , vol.16 , pp. 2351-2355
    • Boyd, G.W.1    Coombs, M.M.2    Ioannides, C.3    Lewis, D.F.V.4    Snelling, J.5    Tsakalof, A.6
  • 6
    • 0020601426 scopus 로고
    • Differential effects of phenobarbitone and 3-methylcholanthrene induction in the hepatic microsomal metabolism and cytochrome P-450 binding of phenoxazone and a homologous series of its n-alkyl ethers (alkoxy resorufins)
    • BURKE, M. D., and MAYER, R. T., 1983, Differential effects of phenobarbitone and 3-methylcholanthrene induction in the hepatic microsomal metabolism and cytochrome P-450 binding of phenoxazone and a homologous series of its n-alkyl ethers (alkoxy resorufins). Chemico-Biological Interactions, 45, 243-258.
    • (1983) Chemico-Biological Interactions , vol.45 , pp. 243-258
    • Burke, M.D.1    Mayer, R.T.2
  • 7
    • 0027475989 scopus 로고
    • Determinants of protein modification versus heme alkylation: Inactivation of cytochrome P4501A1 by 1-ethynylpyrene and phenylacetylene
    • CHAN, W. K., SUI, Z., and ORTIZ DE MONTELLANO, P. R., 1993, Determinants of protein modification versus heme alkylation: inactivation of cytochrome P4501A1 by 1-ethynylpyrene and phenylacetylene. Chemical Research in Toxicology, 6, 38-45.
    • (1993) Chemical Research in Toxicology , vol.6 , pp. 38-45
    • Chan, W.K.1    Sui, Z.2    Ortiz De Montellano, P.R.3
  • 8
    • 0030201065 scopus 로고    scopus 로고
    • Interaction with the aromatic hydrocarbon receptor, CYP1A induction and mutagenicity of a series of diaminotoluenes: Implications for their carcinogenicity
    • in press
    • CHEUNG, Y-L., SNELLING, J., MOHAMMED, N. N. D., GRAY, T. J. B., and IOANNIDES, C., 1996, Interaction with the aromatic hydrocarbon receptor, CYP1A induction and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity. Toxicology and Applied Pharmacology (in press).
    • (1996) Toxicology and Applied Pharmacology
    • Cheung, Y.-L.1    Snelling, J.2    Mohammed, N.N.D.3    Gray, T.J.B.4    Ioannides, C.5
  • 11
    • 0027443640 scopus 로고
    • Molecular evolution of P450 superfamily and P450-containing mono-oxygenase systems
    • DEGTYARENKO, K. N., and ARCHAKOV, A. I., 1993, Molecular evolution of P450 superfamily and P450-containing mono-oxygenase systems. FEBS Letters, 332, 1-8.
    • (1993) FEBS Letters , vol.332 , pp. 1-8
    • Degtyarenko, K.N.1    Archakov, A.I.2
  • 12
    • 0018936478 scopus 로고
    • Inhibition of cytochrome P-448 mixed function oxidase activity following administration of O-hydroxyellipticine to rats
    • DELAFORGE, M., IOANNIDES, C., and PARKE, D. V., 1980, Inhibition of cytochrome P-448 mixed function oxidase activity following administration of O-hydroxyellipticine to rats. Chemico-Biological Interactions, 32, 101-110.
    • (1980) Chemico-Biological Interactions , vol.32 , pp. 101-110
    • Delaforge, M.1    Ioannides, C.2    Parke, D.V.3
  • 15
    • 0027220308 scopus 로고
    • Identification of the epitope of an anti-peptide antibody which binds to CYP1A2 in many species including man
    • EDWARDS, R. J., MURRAY, B. P., SINGLETON, A. M., MURRAY, S., DAVIES, D. S., and BOOBIS, A. R., 1993, Identification of the epitope of an anti-peptide antibody which binds to CYP1A2 in many species including man. Biochemical Pharmacology, 46, 213-220.
    • (1993) Biochemical Pharmacology , vol.46 , pp. 213-220
    • Edwards, R.J.1    Murray, B.P.2    Singleton, A.M.3    Murray, S.4    Davies, D.S.5    Boobis, A.R.6
  • 18
    • 0025922972 scopus 로고
    • hm 3 and other inducible bacterial P450 cytochromes: Biochemistry and regulation
    • hm 3 and other inducible bacterial P450 cytochromes: biochemistry and regulation. Annual Review of Pharmacology and Toxicology, 31, 177-203.
    • (1991) Annual Review of Pharmacology and Toxicology , vol.31 , pp. 177-203
    • Fulco, A.J.1
  • 20
    • 0024457966 scopus 로고
    • Site-directed mutageneses of rat liver cytochrome P-450d: Catalytic activities toward benzphetamine and 7-ethoxycoumarin
    • FURUYA, H., SHIMIZU, T., HIRANO, K., HATANO, M., FUJII-KURIYAMA, Y., RAAG, R., and POULOS, T. L., 1989b, Site-directed mutageneses of rat liver cytochrome P-450d: catalytic activities toward benzphetamine and 7-ethoxycoumarin. Biochemistry, 28, 6848-6857.
    • (1989) Biochemistry , vol.28 , pp. 6848-6857
    • Furuya, H.1    Shimizu, T.2    Hirano, K.3    Hatano, M.4    Fujii-Kuriyama, Y.5    Raag, R.6    Poulos, T.L.7
  • 22
    • 0026082836 scopus 로고
    • cDNA-expressed human cytochrome P450s: A new age of molecular toxicology and human risk assessment
    • GONZALEZ, F. J. and CRESPI, C. L., and GELBOIN, H. V., 1991, cDNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessment. Mutation Research, 247, 113-127.
    • (1991) Mutation Research , vol.247 , pp. 113-127
    • Gonzalez, F.J.1    Crespi, C.L.2    Gelboin, H.V.3
  • 23
    • 0028272001 scopus 로고
    • Role of human cytochromes P450 in the metabolic activation of chemical carcinogen and toxins
    • GONZALEZ, F. J., and GELBOIN, H. V., 1994, Role of human cytochromes P450 in the metabolic activation of chemical carcinogen and toxins. Drug Metabolism Reviews, 26, 165-183.
    • (1994) Drug Metabolism Reviews , vol.26 , pp. 165-183
    • Gonzalez, F.J.1    Gelboin, H.V.2
  • 25
    • 0023951396 scopus 로고
    • Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy
    • GUENGERICH, F. P., 1988, Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Research, 48, 2946-2954.
    • (1988) Cancer Research , vol.48 , pp. 2946-2954
    • Guengerich, F.P.1
  • 26
    • 0026507870 scopus 로고
    • Human cytochrome P-450 enzymes
    • GUENGERICH, F. P., 1992a, Human cytochrome P-450 enzymes. Life Sciences, 50, 1471-1478.
    • (1992) Life Sciences , vol.50 , pp. 1471-1478
    • Guengerich, F.P.1
  • 28
    • 0001680211 scopus 로고
    • Cytochrome P450 enzymes
    • GUENGERICH, F. P., 1993, Cytochrome P450 enzymes. American Scientist, 81, 440-447.
    • (1993) American Scientist , vol.81 , pp. 440-447
    • Guengerich, F.P.1
  • 29
    • 0027954308 scopus 로고
    • Catalytic selectivity of human cytochrome P450 enzymes: Relevance to drug metabolism and toxicity
    • GUENGERICH, F. P., 1994, Catalytic selectivity of human cytochrome P450 enzymes: relevance to drug metabolism and toxicity, Toxicology Letters, 70, 133-138.
    • (1994) Toxicology Letters , vol.70 , pp. 133-138
    • Guengerich, F.P.1
  • 30
    • 0025992864 scopus 로고
    • Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
    • GUENGERICH, F. P., and SHIMADA, T., 1991, Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chemical Research in Toxicology, 4, 391-407.
    • (1991) Chemical Research in Toxicology , vol.4 , pp. 391-407
    • Guengerich, F.P.1    Shimada, T.2
  • 32
    • 0027457924 scopus 로고
    • Engineering of cytochrome P450 2B1 specificity
    • HALPERT, J. R., and HE, Y., 1993, Engineering of cytochrome P450 2B1 specificity. Journal of Biological Chemistry, 268, 4453-4457.
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 4453-4457
    • Halpert, J.R.1    He, Y.2
  • 36
    • 0025914145 scopus 로고
    • Genetic linkage of lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene
    • HAYASHI, S. I., WATANABE, J., NAKACHI, K., and KAWAJIRI, K., 1991, Genetic linkage of lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene. Journal of Biochemistry, 110, 407-411.
    • (1991) Journal of Biochemistry , vol.110 , pp. 407-411
    • Hayashi, S.I.1    Watanabe, J.2    Nakachi, K.3    Kawajiri, K.4
  • 38
    • 0025313982 scopus 로고
    • The cytochrome P4501 gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals
    • IOANNIDES, C., and PARKE, D. V., 1990, The cytochrome P4501 gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals. Drug Metabolism Reviews, 22, 1-85.
    • (1990) Drug Metabolism Reviews , vol.22 , pp. 1-85
    • Ioannides, C.1    Parke, D.V.2
  • 39
    • 0027751340 scopus 로고
    • Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis
    • IOANNIDES, C., and PARKE, D. V., 1993, Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis. Drug Metabolism Reviews, 25, 485-501.
    • (1993) Drug Metabolism Reviews , vol.25 , pp. 485-501
    • Ioannides, C.1    Parke, D.V.2
  • 41
    • 0002844452 scopus 로고
    • The role of cytochrome P-450 in the metabolism of chemical carcinogens
    • edited by F. P. Guengerich (CRC Press, Boca Raton)
    • KADLUBAR, F. F., and HAMMONS, G. J., 1987, The role of cytochrome P-450 in the metabolism of chemical carcinogens. In Mammalian Cytochromes P-450, edited by F. P. Guengerich (CRC Press, Boca Raton), vol. 2, 81-130.
    • (1987) Mammalian Cytochromes P-450 , vol.2 , pp. 81-130
    • Kadlubar, F.F.1    Hammons, G.J.2
  • 44
    • 0027411643 scopus 로고
    • Predicting the cytochrome P450 mediated metabolism of xenobiotics
    • KORZEKWA, K. R., and JONES, J. P., 1993, Predicting the cytochrome P450 mediated metabolism of xenobiotics. Pharmacogenetics, 3, 1-18.
    • (1993) Pharmacogenetics , vol.3 , pp. 1-18
    • Korzekwa, K.R.1    Jones, J.P.2
  • 46
    • 0027380074 scopus 로고
    • Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline
    • KUNZE, K. L., and TRAGER, W. F., 1993, Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline. Chemical Research in Toxicology, 6, 649-656.
    • (1993) Chemical Research in Toxicology , vol.6 , pp. 649-656
    • Kunze, K.L.1    Trager, W.F.2
  • 48
    • 0001988012 scopus 로고
    • Computer modelling of cytochromes P-450 and their substrates: A rational approach to the prediction of carcinogenicity
    • LEWIS, D. F. V., 1992, Computer modelling of cytochromes P-450 and their substrates: a rational approach to the prediction of carcinogenicity. Frontiers in Biotransformation, 7, 90-136.
    • (1992) Frontiers in Biotransformation , vol.7 , pp. 90-136
    • Lewis, D.F.V.1
  • 49
    • 0011976424 scopus 로고
    • Molecular structural studies in the rationalization of xenobiotic metabolism and toxicity
    • LEWIS, D. F. V., 1994, Molecular structural studies in the rationalization of xenobiotic metabolism and toxicity. Toxicology and Ecotoxicology News, 1, 108-112.
    • (1994) Toxicology and Ecotoxicology News , vol.1 , pp. 108-112
    • Lewis, D.F.V.1
  • 51
    • 0002368374 scopus 로고
    • Molecular modelling of mammalian cytochromes P450 with specific substrates and inhibitors
    • edited by C. Ioannides (CRC Press, Boca Raton) (in press)
    • LEWIS, D. F. V., 1995b, Molecular modelling of mammalian cytochromes P450 with specific substrates and inhibitors. In Cytochromes P450: Metabolic and Toxicological Aspects, edited by C. Ioannides (CRC Press, Boca Raton) (in press).
    • (1995) Cytochromes P450: Metabolic and Toxicological Aspects
    • Lewis, D.F.V.1
  • 52
    • 0029513105 scopus 로고
    • COMPACT and the importance of frontier orbitals in toxicity
    • LEWIS, D. F. V., 1995c, COMPACT and the importance of frontier orbitals in toxicity, Toxicology Modelling, 1, 85-97.
    • (1995) Toxicology Modelling , vol.1 , pp. 85-97
    • Lewis, D.F.V.1
  • 53
    • 3042930847 scopus 로고
    • The cytochromes P450: Ubiquitous enzymes of metabolism
    • LEWIS, D. F. V., 1995d, The cytochromes P450: ubiquitous enzymes of metabolism, Manufacturing Chemist, 66, 35-37.
    • (1995) Manufacturing Chemist , vol.66 , pp. 35-37
    • Lewis, D.F.V.1
  • 55
    • 0029088125 scopus 로고
    • Molecular modelling of members of the P4502A subfamily: Application to studies of enzyme specificity
    • LEWIS, D. F. V., and LAKE, B. G., 1995, Molecular modelling of members of the P4502A subfamily: application to studies of enzyme specificity, Xenobiotica, 25, 585-598.
    • (1995) Xenobiotica , vol.25 , pp. 585-598
    • Lewis, D.F.V.1    Lake, B.G.2
  • 57
    • 0026874828 scopus 로고
    • The sequence homologies of cytochromes P450 and active site geometries
    • LEWIS, D. F. V., and MOEREELS, H., 1992, The sequence homologies of cytochromes P450 and active site geometries. Journal of Computer-Aided Molecular Design, 6, 235-252.
    • (1992) Journal of Computer-Aided Molecular Design , vol.6 , pp. 235-252
    • Lewis, D.F.V.1    Moereels, H.2
  • 58
    • 0028969933 scopus 로고
    • The genotoxicity of benzanthracenes: A quantitative structure-activity study
    • LEWIS, D. F. V., and PARKE, D. V., 1995, The genotoxicity of benzanthracenes: a quantitative structure-activity study, Mutation Research, 328, 207-214.
    • (1995) Mutation Research , vol.328 , pp. 207-214
    • Lewis, D.F.V.1    Parke, D.V.2
  • 59
    • 0022521078 scopus 로고
    • Molecular dimensions of the substrate binding site of cytochrome P-448
    • LEWIS, D. F. V., IOANNIDES, C., and PARKE, D. V., 1986, Molecular dimensions of the substrate binding site of cytochrome P-448. Biochemical Pharmacology, 35, 2179-2185.
    • (1986) Biochemical Pharmacology , vol.35 , pp. 2179-2185
    • Lewis, D.F.V.1    Ioannides, C.2    Parke, D.V.3
  • 60
    • 0023553590 scopus 로고
    • Structural requirements for substrates of cytochromes P-450 and P-448
    • LEWIS, D. F. V., IOANNIDES, C., and PARKE, D. V., 1987, Structural requirements for substrates of cytochromes P-450 and P-448, Chemico-Biological Interactions, 64, 39-60.
    • (1987) Chemico-Biological Interactions , vol.64 , pp. 39-60
    • Lewis, D.F.V.1    Ioannides, C.2    Parke, D.V.3
  • 61
    • 0028352196 scopus 로고
    • Molecular modelling of enzymes and receptors involved in carcinogenesis: QSARs and COMPACT-3D
    • LEWIS, D. F. V., MOEREELS, H., LAKE, B. G., IOANNIDES, C., and PARKE, D. V., 1994a, Molecular modelling of enzymes and receptors involved in carcinogenesis: QSARs and COMPACT-3D, Drug Metabolism Reviews, 26, 261-185.
    • (1994) Drug Metabolism Reviews , vol.26 , pp. 261-1185
    • Lewis, D.F.V.1    Moereels, H.2    Lake, B.G.3    Ioannides, C.4    Parke, D.V.5
  • 62
    • 0028198736 scopus 로고
    • Molecular modelling of cytochrome P4501A1: A putative access channel explains activity differences between structurally related benzo[a]pyrene and benzo[e]pyrene, and 2-acetylaminofluorene and 4-acetylaminofluorene
    • LEWIS, D. F. V., IOANNIDES, C., and PARKE, D. V., 1994b, Molecular modelling of cytochrome P4501A1: a putative access channel explains activity differences between structurally related benzo[a]pyrene and benzo[e]pyrene, and 2-acetylaminofluorene and 4-acetylaminofluorene, Toxicology Letters, 71, 235-243.
    • (1994) Toxicology Letters , vol.71 , pp. 235-243
    • Lewis, D.F.V.1    Ioannides, C.2    Parke, D.V.3
  • 63
    • 0027992619 scopus 로고
    • Inhibition of rat hepatic aryl hydrocarbon hydroxylase activity by a series of 7-hydroxy coumarins : QSAR studies
    • LEWIS, D. F. V., LAKE, B. G., IOANNIDES, C., and PARKE, D. V., 1994c, Inhibition of rat hepatic aryl hydrocarbon hydroxylase activity by a series of 7-hydroxy coumarins : QSAR studies, Xenobiotica, 24, 829-838.
    • (1994) Xenobiotica , vol.24 , pp. 829-838
    • Lewis, D.F.V.1    Lake, B.G.2    Ioannides, C.3    Parke, D.V.4
  • 64
    • 0028923838 scopus 로고
    • Computer graphics analysis of the interaction of alkoxy methylenedioxygenzenes with cytochromes P4501
    • LEWIS, D. F. V., IOANNIDES, C., and PARKE, D. V., 1995a, Computer graphics analysis of the interaction of alkoxy methylenedioxygenzenes with cytochromes P4501, Toxicology Letters, 76, 39-45.
    • (1995) Toxicology Letters , vol.76 , pp. 39-45
    • Lewis, D.F.V.1    Ioannides, C.2    Parke, D.V.3
  • 65
    • 0029589468 scopus 로고
    • Molecular orbital-generated quantitative structure-activity relationships in a homologous series of alkoxy resorufins
    • LEWIS, D. F. V., LAKE, B. G., and PARKE, D. V., 1995b, Molecular orbital-generated quantitative structure-activity relationships in a homologous series of alkoxy resorufins, Xenobiotica, 25, 1355-1369.
    • (1995) Xenobiotica , vol.25 , pp. 1355-1369
    • Lewis, D.F.V.1    Lake, B.G.2    Parke, D.V.3
  • 66
    • 0343276205 scopus 로고
    • Molecular modelling of mammalian cytochromes P450 and evaluation of chemical toxicity and metabolism using COMPACT
    • edited by F. Sanz (Prous, Paris) (in press)
    • LEWIS, D. F. V., IOANNIDES, C., and PARKE, D. V., 1995c, Molecular modelling of mammalian cytochromes P450 and evaluation of chemical toxicity and metabolism using COMPACT. In: QSAR and Molecular Modelling, edited by F. Sanz (Prous, Paris) (in press).
    • (1995) QSAR and Molecular Modelling
    • Lewis, D.F.V.1    Ioannides, C.2    Parke, D.V.3
  • 67
    • 0024976419 scopus 로고
    • coh substrate specificity by mutation of a single amino-acid residue
    • coh substrate specificity by mutation of a single amino-acid residue, Nature, 339, 632-634.
    • (1989) Nature , vol.339 , pp. 632-634
    • Lindberg, R.L.P.1    Negishi, M.2
  • 68
    • 0027503325 scopus 로고
    • cam to increase the stereospecificity and coupling of aliphatic hydroxylation
    • cam to increase the stereospecificity and coupling of aliphatic hydroxylation, Protein Engineering, 6, 207-212.
    • (1993) Protein Engineering , vol.6 , pp. 207-212
    • Loida, P.J.1    Sligar, S.G.2
  • 69
    • 0025296345 scopus 로고
    • Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochrome P-450
    • MCMANUS, M. E., BURGESS, W. M., VERONESE, M. E., HUGGETT, A., QUATTROCHI, L. C., and TUKEY, R. H., 1990, Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochrome P-450, Cancer Research, 50, 3367-3376.
    • (1990) Cancer Research , vol.50 , pp. 3367-3376
    • Mcmanus, M.E.1    Burgess, W.M.2    Veronese, M.E.3    Huggett, A.4    Quattrochi, L.C.5    Tukey, R.H.6
  • 72
    • 0029031273 scopus 로고
    • Identification of cytochrome P-450 1A (CYP1A) genes from two teleost fish, toadfish (Opsanus tau) and scup (Stenotomus chrysops), and phylogenetic analysis of CYP1A genes
    • MORRISON, K. G., OLEKSIAK, M. F., CORNELL, N. W., SOGIN, M. L., and STEGEMAN, J. J., 1995, Identification of cytochrome P-450 1A (CYP1A) genes from two teleost fish, toadfish (Opsanus tau) and scup (Stenotomus chrysops), and phylogenetic analysis of CYP1A genes, Biochemical Journal, 308, 97-104.
    • (1995) Biochemical Journal , vol.308 , pp. 97-104
    • Morrison, K.G.1    Oleksiak, M.F.2    Cornell, N.W.3    Sogin, M.L.4    Stegeman, J.J.5
  • 74
    • 0028662025 scopus 로고
    • P450 in the rat and man: Methods of investigation, substrate specificities and relevance to cancer
    • NEDELCHEVA, V., and GUT, I., 1994, P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer, Xenobiotica, 24, 1151-1175.
    • (1994) Xenobiotica , vol.24 , pp. 1151-1175
    • Nedelcheva, V.1    Gut, I.2
  • 78
    • 0027179679 scopus 로고
    • Methoxyresorufin and benzyloxyresorufin: Substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse
    • NERURKAR, P. V., PARK, S. S., THOMAS, P. E., NIMS, R. W., and LUBET, R. A., 1993, Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse, Biochemical Pharmacology, 46, 933-943.
    • (1993) Biochemical Pharmacology , vol.46 , pp. 933-943
    • Nerurkar, P.V.1    Park, S.S.2    Thomas, P.E.3    Nims, R.W.4    Lubet, R.A.5
  • 79
    • 0344190454 scopus 로고
    • Microsomal enzymes and toxicity
    • edited by A. R. Boobis, J. Caldwell, F. De Matteis and C. R. Elcombe (Taylor & Francis, London)
    • PARKE, D. V., IOANNIDES, C., IWASAKI, K., and LEWIS, D. F. V., 1985, Microsomal enzymes and toxicity. In Microsomes and Drug Oxidations, edited by A. R. Boobis, J. Caldwell, F. De Matteis and C. R. Elcombe (Taylor & Francis, London), pp. 402-413.
    • (1985) Microsomes and Drug Oxidations , pp. 402-413
    • Parke, D.V.1    Ioannides, C.2    Iwasaki, K.3    Lewis, D.F.V.4
  • 81
    • 0028285404 scopus 로고
    • Polycyclic hydrocarbon activation: Bay regions and beyond
    • PHILLIPS, D. H., and GROVER, P. L., 1994, Polycyclic hydrocarbon activation: bay regions and beyond, Drug Metabolism Reviews, 26, 443-467.
    • (1994) Drug Metabolism Reviews , vol.26 , pp. 443-467
    • Phillips, D.H.1    Grover, P.L.2
  • 82
    • 0025784027 scopus 로고
    • Cytochromes P-450: Multiplicity of isoforms, substrates and catalytic and regulatory mechanisms
    • PORTER, T. D., and COON, M. J., 1991, Cytochromes P-450: multiplicity of isoforms, substrates and catalytic and regulatory mechanisms, Journal of Biological Chemistry, 266, 13469-13472.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 13469-13472
    • Porter, T.D.1    Coon, M.J.2
  • 83
    • 0027326717 scopus 로고
    • Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450s
    • RAVICHANDRAN, K. G., BODDUPALLI, S. S., HASEMANN, C. A., PETERSON, J. A., and DEISENHOFER, J., 1993, Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450s, Science, 261, 731-736.
    • (1993) Science , vol.261 , pp. 731-736
    • Ravichandran, K.G.1    Boddupalli, S.S.2    Hasemann, C.A.3    Peterson, J.A.4    Deisenhofer, J.5
  • 85
    • 0345384416 scopus 로고
    • Carcinogenic activation of cooked food heterocyclic amines by cytochrome P450 1A2. A theoretical study
    • edited by M. C. Lechner (John Libbey, Paris)
    • SANZ, F., LOZANO, J. J., LOPEZ-DE-BRINAS, E., DE-LA-TORRE, R., and MANAUT, F., 1994b, Carcinogenic activation of cooked food heterocyclic amines by cytochrome P450 1A2. A theoretical study. In Cytochrome P450. 8th International Conference, edited by M. C. Lechner (John Libbey, Paris), pp. 575-578.
    • (1994) Cytochrome P450. 8th International Conference , pp. 575-578
    • Sanz, F.1    Lozano, J.J.2    Lopez-De-Brinas, E.3    De-La-Torre, R.4    Manaut, F.5
  • 87
    • 0024365294 scopus 로고
    • Human liver microsomal cytochrome P450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella Tryphimurium TA 1535/pSK1002
    • SHIMADA, T., IWASAKI, M., MARTIN, M. V., and GUENGERICH, F. P., 1989, Human liver microsomal cytochrome P450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella Tryphimurium TA 1535/pSK1002, Cancer Research, 49, 3218-3228.
    • (1989) Cancer Research , vol.49 , pp. 3218-3228
    • Shimada, T.1    Iwasaki, M.2    Martin, M.V.3    Guengerich, F.P.4
  • 88
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals
    • SHIMADA, T., YAMAZAKI, H., MIMURA, M., INUI, Y., and GUENGERICH, F. P., 1994, Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals, Journal of Pharmacology and Experimental Therapeutics, 270, 414-423.
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 89
    • 0028181731 scopus 로고
    • 319 mutants of cytochrome P4501A2 remarkably enhance homolytic O-O cleavage of alkyl hydroperoxides
    • 319 mutants of cytochrome P4501A2 remarkably enhance homolytic O-O cleavage of alkyl hydroperoxides, Journal of Biological Chemistry, 269, 13296-13304.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 13296-13304
    • Shimizu, T.1    Murakami, Y.2    Hatano, M.3
  • 90
    • 8944224010 scopus 로고    scopus 로고
    • Cytochromes P450: Selectivity and measurement in vivo
    • in press
    • SMITH, D. A., ABEL, S. M., HYLAND, R., and JONES, B. C., 1996, Cytochromes P450: selectivity and measurement in vivo, Xenobiotica, 26 (in press).
    • (1996) Xenobiotica , vol.26
    • Smith, D.A.1    Abel, S.M.2    Hyland, R.3    Jones, B.C.4
  • 91
    • 0027749573 scopus 로고
    • Metabolism of the food-derived mutagen/carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates
    • SNYDERWINE, E. G., BUONARATI, M. H., FELTON, J. S., and TURTLETAUB, K. W., 1993, Metabolism of the food-derived mutagen/carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates, Carcinogenesis, 14, 2517-2522.
    • (1993) Carcinogenesis , vol.14 , pp. 2517-2522
    • Snyderwine, E.G.1    Buonarati, M.H.2    Felton, J.S.3    Turtletaub, K.W.4
  • 92
    • 0026569805 scopus 로고
    • Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms
    • SOUCEK, P., and GUT, I., 1992, Cytochromes P-450 in rats: structures, functions, properties and relevant human forms, Xenobiotica, 22, 83-103.
    • (1992) Xenobiotica , vol.22 , pp. 83-103
    • Soucek, P.1    Gut, I.2
  • 93
    • 0029131555 scopus 로고
    • Clinical importance of hepatic cytochrome P450 in drug metabolism
    • SPATZENEGGER, M., and JAEGER, W., 1995, Clinical importance of hepatic cytochrome P450 in drug metabolism, Drug Metabolism Reviews, 27, 397-417.
    • (1995) Drug Metabolism Reviews , vol.27 , pp. 397-417
    • Spatzenegger, M.1    Jaeger, W.2
  • 95
    • 0027523656 scopus 로고
    • The cytochrome P4501A2 active site: Topology and perturbations caused by glutamic acid-318 and threonine-319 mutations
    • TUCK, S. F., HIROYA, K., SHIMIZU, T., HATANO, M., and ORTIZ DE MONTELLANO, P. R., 1993, The cytochrome P4501A2 active site: topology and perturbations caused by glutamic acid-318 and threonine-319 mutations, Biochemistry, 32, 2548-2533.
    • (1993) Biochemistry , vol.32 , pp. 2548-12533
    • Tuck, S.F.1    Hiroya, K.2    Shimizu, T.3    Hatano, M.4    Ortiz De Montellano, P.R.5
  • 96
    • 0026674934 scopus 로고
    • Active site topologies of bacterial cytochromes P450101 (P450cam), P450108 (P450terp) and P450102 (P450BM-3): In situ rearrangement of their phenyl-iron complexes
    • TUCK, S. F., PETERSON, J. A., and ORTIZ DE MONTELLANO, P. R., 1992, Active site topologies of bacterial cytochromes P450101 (P450cam), P450108 (P450terp) and P450102 (P450BM-3): in situ rearrangement of their phenyl-iron complexes, Journal of Biological Chemistry, 267, 5614-5620.
    • (1992) Journal of Biological Chemistry , vol.267 , pp. 5614-5620
    • Tuck, S.F.1    Peterson, J.A.2    Ortiz De Montellano, P.R.3
  • 97
    • 0026583809 scopus 로고
    • Food-derived mutagens and carcinogens
    • WAKABAYASHI, K., NAGAO, M., ESUMI, H., and SUGIMURA, T., 1992, Food-derived mutagens and carcinogens, Cancer Research, 52 (suppl.), 20925-20985.
    • (1992) Cancer Research , vol.52 , Issue.SUPPL. , pp. 20925-20985
    • Wakabayashi, K.1    Nagao, M.2    Esumi, H.3    Sugimura, T.4
  • 98
    • 0023866757 scopus 로고
    • Stereoselectivity of cytochrome P-450 isozymes and epoxide hydrolase in the metabolism of polycyclic aromatic hydrocarbons
    • YANG, S. K., 1988, Stereoselectivity of cytochrome P-450 isozymes and epoxide hydrolase in the metabolism of polycyclic aromatic hydrocarbons, Biochemical Pharmacology, 37, 61-70.
    • (1988) Biochemical Pharmacology , vol.37 , pp. 61-70
    • Yang, S.K.1
  • 99
    • 0026468125 scopus 로고
    • Modification of cytochrome P4501A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl
    • YUN, C.-H., HAMMONS, G. J., JONES, G., MARTIN, M. V., HOPKINS, N. E., ALWORTH, W. L., and GUENGERICH, F. P., 1992, Modification of cytochrome P4501A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl, Biochemistry, 31, 10556-10563.
    • (1992) Biochemistry , vol.31 , pp. 10556-10563
    • Yun, C.-H.1    Hammons, G.J.2    Jones, G.3    Martin, M.V.4    Hopkins, N.E.5    Alworth, W.L.6    Guengerich, F.P.7
  • 100
    • 0028301237 scopus 로고
    • Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phenylimidazo (4,5-b) pyridine (PhIP) by human liver microsomes
    • ZHAO, K., MURRAY, S., DAVIES, D. S., BOOBIS, A. R., and GOODERHAM, N. J., 1994, Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phenylimidazo (4,5-b) pyridine (PhIP) by human liver microsomes, Carcinogenesis, 15, 1285-1288.
    • (1994) Carcinogenesis , vol.15 , pp. 1285-1288
    • Zhao, K.1    Murray, S.2    Davies, D.S.3    Boobis, A.R.4    Gooderham, N.J.5
  • 101
    • 0026073511 scopus 로고
    • A predicted three-dimensional structure of human cytochrome P450: Implications for substrate specificity
    • ZVELEBIL, M. J. J. M., WOLF, C. R., and STERNBERG, M. J. E., 1991, A predicted three-dimensional structure of human cytochrome P450: implications for substrate specificity, Protein Engineering, 4, 271-281.
    • (1991) Protein Engineering , vol.4 , pp. 271-281
    • Zvelebil, M.J.J.M.1    Wolf, C.R.2    Sternberg, M.J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.