A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39485-39492

  Li, Jun ^a   Barnard, Daron C ^b   Patton, James G ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANIC ACIDS; PROTEINS; RNA;

INACTIVATED SPLICING;

BIOCHEMISTRY;

CHIMERIC PROTEIN; GLUTAMIC ACID; LYSINE; PROTEIN; PROTEIN SRRP 86; RNA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; MODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE;

ANIMALIA; INSERTION SEQUENCES;

EID: 0037131182     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M201784200     Document Type: Article

References (63)

1. Burge, C. B., Tuschl, T., and Sharp, P. A. (1999) in The RNA World (Gesteland, R. F., Cech, T. R., and Atkins, J. F., eds), pp. 525-560, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 2nd Ed.
2. Smith, C. W. J., and Valcárcel, J. (2000) Trends Biochem. Sci. 25, 381-388
3. Gravely, B. R. (2001) Trends Genet. 17, 100-107
4. Consortium, I. H. G. S. (2001) Nature 409, 860-921
5. Brett, D., Pospisil, H., Valcarcel, J., and Bork, P. (2001) Nat. Genet. 30, 29-30
6. Krawczak, M., Reiss, J., and Cooper, D. N. (1992) Hum. Genet. 90, 41-54
7. Patton, J. G., and Smith, C. W. J. (2001) in Encyclopedia of Molecular Medicine (Creighton, T. E., ed), John Wiley, New York
8. Robberson, B. L., Cote, G., and Berget, S. M. (1990) Mol. Cell. Biol. 10, 84094
9. Berget, S. M. (1995) J. Biol. Chem. 270, 2411-2414
10. Wu, J. Y., and Maniatis, T. (1993) Cell 75, 1061-1070
11. Kohtz, J. D., Jamison, S. F., Will, C. L., Zuo, P., Lührmann, R., Garcia-Blanco, M. A., and Manley, J. (1994) Nature 368, 119-124
12. Staknis, D., and Reed, R. (1994) Mol. Cell. Biol. 14, 7670-7682
13. Tarn, W.-Y., and Steitz, J. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2504-2508
14. Abovich, N., and Rosbash, M. (1997) Cell 89, 403-412
15. Gravely, B. R. (2000) RNA 6, 1197-1211
16. Kennedy, C. F., Kämer, A., and Berget, S. M. (1998) Mol. Cell. Biol. 18, 5425-5434
17. Zhang, W. J., and Wu, J. Y. (1996) Mol. Cell. Biol. 16, 5400-5408
18. Amrein, H., Hedley, M. L., and Maniatis, T. (1994) Cell 76, 735-746
19. Xiao, S. H., and Manley, J. L. (1997) Genes Dev. 11, 334-344
20. Colwill, K., Pawson, T., Andrews, B., Prasad, J., Manley, J. L., Bell, J. C., and Duncan, P. I. (1996) EMBO J. 15, 265-275
21. Gui, J. F., Tronchere, H., Chandler, S. D., and Fu, X.-D. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10824-10828
22. Tronchere, H., Wang, J., and Fu, X.-D. (1997) Nature 388, 397-400
23. Blencowe, B. J., Issner, R., Nickerson, J. A., and Sharp, P. A. (1998) Genes Dev. 12, 996-1009
24. Blencowe, B. J. (2000) Trends Biochem. Sci. 25, 106-110
25. Longman, D., Johnstone, I. L., and Cáceres, J. F. (2000) EMBO J. 19, 1625-1637
26. Wang, J., Takagaki, Y., and Manley, J. L. (1996) Genes Dev. 10, 2588-2599
27. Ring, H. Z., and Lis, J. T. (1994) Mol. Cell. Biol. 14, 7499-7506
28. Fu, X.-D. (1993) Nature 365, 82-85
29. Screaton, G. R., Cáceres, J. F., Mayeda, A., Bell, M. V., Plebanski, M., Jackson, D. G., Bell, J. I., and Krainer, A. R. (1995) EMBO J. 14, 4336-4349
30. Wang, J., and Manley, J. L. (1995) RNA 1, 335-346
31. Heinrichs, V., and Baker, B. S. (1995) EMBO J. 14, 3987-4000
32. Zuo, P., and Manley, J. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 3363-3367
33. Tacke, R., and Manley, J. L. (1995) EMBO J. 14, 3540-3551
34. Shi, H., Hoffman, B. E., and Lis, J. T. (1997) Mol. Cell. Biol. 17, 2649-2657
35. Tacke, R., Chen, Y., and Manley, J. L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1148-1153
36. Mayeda, A., Screaton, G. R., Chandler, S. D., Fu, X.-D., and Krainer, A. R. (1999) Mol. Cell. Biol. 19, 1853-1863
37. Bourgeois, C. F., Popielarz, M., Hildwein, G., and Stevenin, J. (1999) Mol. Cell. Biol. 19, 7347-7356
38. Cavaloc, Y., Bourgeois, C. F., Kister, L., and Stevenin, J. (1999) RNA 5, 468-483
39. Mayeda, A., Helfman, D. M., and Krainer, A. R. (1993) Mol. Cell. Biol. 13, 2993-3001
40. Mayeda, A., and Krainer, A. R. (1992) Cell 68, 365-375
41. Gallego, M. E., Gattoni, R., Stevenin, J., Marie, J., and Expert-Bezancon, A. (1997) EMBO J. 16, 1772-1784
42. Jumaa, H., and Nielsen, P. J. (1997) EMBO J. 16, 5077-5085
43. Kanopka, A., Muhlemann, O., and Akusjarvi, G. (1996) Nature 381, 535-538
44. Barnard, D. C., and Patton, J. G. (2000) Mol. Cell. Biol. 20, 3049-3057
45. Cowper, A. E., Cáceres, J. F., Mayeda, A., and Screaton, G. R. (2001) J. Biol. Chem. 276, 48908-48914
46. van der Houven van Oordt, W., Newton, K., Screaton, G., and Cáceres, J. F. (2000) Nucleic Acids Res. 28, 4822-4831
47. Chandler, S. D., Mayeda, A., Yeakley, J. M., Krainer, A. R., and Fu, X. D. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3596-3601
48. Barnard, D., Li, J., Peng, R., and Patton, J. G. (2002) RNA 8, 526-533
49. Pérez, I., McAfee, J. G., and Patton, J. G. (1997) Biochemistry 36, 11881-11890
50. Reed, R., and Maniatis, T. (1986) Cell 46, 681-690
51. Dye, B. T., Buvoli, M., Mayer, S. A., Lin, C.-H., and Patton, J. G. (1998) RNA 4, 1523-1536
52. Coolidge, C. J., Seely, R. J., and Patton, J. G. (1997) Nucleic Acids Res. 25, 888-896
53. Konarska, M. M., and Sharp, P. A. (1986) Cell 46, 845-855
54. Krämer, A. (1996) Annu. Rev. Biochem. 65, 367-409
55. Cáceres, J. F., and Krainer, A. R.(1993) EMBO J. 12, 4715-4726
56. Zuo, P., and Manley, J. L. (1993) EMBO J. 12, 4727-4737
57. Zahler, A. M., Lane, W. S., Stolk, J. A., and Roth, M. B. (1992) Genes Dev. 6, 837-847
58. Zahler, A. M., Neugebauer, K. M., Lane, W. S., and Roth, M. (1993) Science 260, 219-222
59. Jumaa, H., and Nielsen, P. J. (2000) Biochim. Biophys. Acta 1494, 137-1434
60. Nayler, O., Stratling, W., Bourquin, J.-P., Stagljar, I., Lindemann, L., Jasper, H., Hartmann, A. M., Fackelmayer, F. O., Ullrich, A., and Stamm, S. (1998) Nucleic Acids Res. 26, 3542-3549
61. Nikolakaki, E., Kohen, R., Hartmann, A. M., Stamm, S., Georgatsou, E., and Giannakouros, T. (2001) J. Biol. Chem. 276, 40175-40182
62. Hartmann, A. M., Nayler, O., Schwaiger, F. W., Obermeier, A., and Stamm, S. (1999) Mol. Biol. Cell 10, 3909-3926
63. Corpet, F. (1988) Nucleic Acids Res. 16, 10881-10890