Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins

RNA

Volumn 8, Issue 4, 2002, Pages 526-533

  Barnard, Daron C ^a   Li, Jun ^a   Peng, Rui ^a   Patton, James G ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Alternative splicing; Pre mRNA splicing; SR proteins; SRrp86

Indexed keywords

DOCKING PROTEIN; MESSENGER RNA PRECURSOR; PROTEIN SRRP86; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CELL LINE; CONTROLLED STUDY; DOSE RESPONSE; EUKARYOTE; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ANALYSIS; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA SPLICING; TRANSLATION REGULATION;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CELLS, CULTURED; HELA CELLS; HUMANS; NUCLEAR PROTEINS; ORGAN SPECIFICITY; PHOSPHOPROTEINS; RATS; RNA-BINDING PROTEINS;

EUKARYOTA;

EID: 0036235583     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838202029928     Document Type: Article

References (46)

1. Identification and characterization of a novel serine-arginine-rich splicing regulatory protein
2. Exonic splicing enhancers: Mechanism of action, diversity and role in human genetic disease
3. Splicing of precursors to mRNAs by spliceosomes
4. Mammalian pre-mRNA splicing factors
5. Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors
6. Functional analysis of the polypyrimidine tract in pre-mRNA splicing
7. SR protein-like factors that antagonize authentic SR proteins and regulate alternative splicing
8. Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer
9. ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome
10. The superfamily of arginine/serine-rich splicing factors
11. Sorting out the complexity of SR protein functions
12. Regulated tissue-specific expression of antagonistic prem-RNA splicing factors
13. Pre-mRNA splicing in the new millennium
14. Pre-mRNA splicing by the essential Drosophila protein B52: Tissue and target specificity
15. Initial sequencing and analysis of the human genome
16. Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability
17. The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation
18. Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins
19. The mutational spectrum of single base pair substitutions in messenger RNA splice junctions of human genes: Causes and consequences
20. hnRNP complexes: Composition, structure, and function
21. Antagonism between RSF1 and SR proteins for both splice-site recognition in vitro and Drosophila development
22. Functional characterization of SR and SR-related genes in Caenorhabditis elegans
23. Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
24. SR proteins and splicing control
25. Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2
26. Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins
27. Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism
28. Upstream open reading frames as regulators of mRNA translation
29. Characterization and molecular cloning of Polypyrimidine Tract Binding Protein: A component of a complex necessary for pre-mRNA splicing
30. Cloning and characterization of PSF, a novel pre-mRNA splicing factor
31. Alternative pre-mRNA splicing: Prevalence, mechanisms, and disease
32. The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation
33. RNA processing and human disease
34. A new view of mRNA export: Separating the wheat from the chaff
35. A general protein purification method for protein complex characterization and proteome exploration
36. SR proteins escort the U4/U6 tri-snRNP to the spliceosome
37. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors
38. Alternative pre-mRNA splicing: The logic of combinatorial control
39. Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: Creation of an SRp40-specific splicing enhancer
40. Determinants of SR protein specificity
41. Post-transcriptional regulation: The dawn of PTB
42. Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways
43. Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability
44. Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing
45. B proteins of heterogeneous nuclear ribonucleo-particles modulate 5′ splice site selection in vivo
46. Human SR proteins and isolation of a cDNA encoding SRp75