Combining structural and bioinformatics methods for the analysis of functionally important residues in DNA glycosylases

Free Radical Biology and Medicine

Volumn 32, Issue 12, 2002, Pages 1254-1263

  Zharkov, Dmitry O ^a,b   Grollman, Arthur P ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

DNA damage; DNA glycosylase; Sequence alignment; Substrate specificity

Indexed keywords

AMINO ACID; DNA; DNA GLYCOSYLTRANSFERASE; GLYCOSIDASE;

BASE PAIRING; BIOINFORMATICS; CATALYSIS; DNA DAMAGE; ENZYME SPECIFICITY; EXCISION REPAIR; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVIEW; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; BIOLOGY; CHEMISTRY; DNA REPAIR; HUMAN; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; DNA; DNA GLYCOSYLASES; DNA REPAIR; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; N-GLYCOSYL HYDROLASES; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037096192     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00828-6     Document Type: Article

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