The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo

Cell

Volumn 105, Issue 4, 2001, Pages 547-558

  O'Connell, Kevin F ^a   Caron, Cathy ^b   Kopish, Kevin R ^a   Hurd, Daryl D ^b   Kemphues, Kenneth J ^b   Li, Yongjing ^a   White, John G ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE;

ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE; CELL ORGANELLE; CENTROSOME; GENE CONTROL; GENE DUPLICATION; GENE LOCATION; GENETIC CODE; MATERNAL BEHAVIOR; NONHUMAN; NUCLEOTIDE SEQUENCE; PATERNAL BEHAVIOR; PRIORITY JOURNAL;

ANIMALIA; CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0035907012     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00338-5     Document Type: Article

References (46)

1. Genome sequence of the nematode C. elegans: A platform for investigating biology
2. Formation of the first cleavage spindle in nematode embryos
3. Segregation of holocentric chromosomes at meiosis in the nematode, Caenorhabditis elegans
4. Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells
5. Trans-splicing and polycistronic transcription in Caenorhabditis elegans
6. The genetics of Caenorhabditis elegans
7. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
8. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle
9. C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2
10. A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
11. Centrosome duplication continues in cycloheximide-treated Xenopus blastulae in the absence of a detectable cell cycle
12. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts
13. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts
14. Early events in DNA replication require cyclin E and are blocked by p21CIP1
15. Maternal-effect lethal mutations on linkage group II of Caenorhabditis elegans
16. Centrosome-independent mitotic spindle formation in vertebrates
17. Germ-line development and fertilization
18. Centriole cycle in Chinese hamster ovary cells as determined by whole-mount electron microscopy
19. Cyclin-dependent kinase control of centrosome duplication
20. Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells
21. The multiplicity of the mitotic centers and the time-couse of their duplication and separation
22. DNA transformation
23. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
24. A role for centrin 3 in centrosome reproduction
25. The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindle
26. A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans
27. The spd-2 gene is required for polarization of the anteroposterior axis and formation of the sperm asters in the Caenorhabditis elegans zygote
28. Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication
29. SCF and APC: The Yin and Yang of cell cycle regulated proteolysis
30. Dependence of centriole formation on protein synthesis
31. Basal body duplication in Paramecium requires gamma-tubulin
32. The centrosome and its mode of inheritance: The reduction of the centrosome during gametogenesis and its restoration during fertilization
33. Control of centrosome reproduction: The right number at the right time
34. Protein synthesis and the cell cycle: Centrosome reproduction in sea urchin eggs is not under translational control
35. Centriole number and the reproductive capacity of spindle poles
36. The checkpoint control for anaphase onset does not monitor excess numbers of spindle poles or bipolar spindle symmetry
37. The origin of pattern and polarity in the Drosophila embryo
38. Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts
39. Pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans
40. The centrosome
41. MPS1 and MPS2: Novel yeast genes defining distinct steps of spindle pole body duplication
42. Spermatogenesis in males of the free-living nematode, Caenorhabditis elegans
43. Patterning in the C. elegans embryo
44. Parental effects and phenotypic characterization of mutations that affect early development in Caenorhabditis elegans
45. Differential regulation of maternal vs. paternal centrosomes