The Induction of Partial Resistance to Photodynamic Therapy by the Protooncogene BCL-2

Photochemistry and Photobiology

Volumn 64, Issue 5, 1996, Pages 845-852

  He, Jin ^a   Agarwal, Munna L ^a   Larkin, Hedy E ^a   Friedman, Libby R ^a   Xue, Liang Yan ^a   Oleinick, Nancy L ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRICETINAE; CRICETULUS GRISEUS;

PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; CHO CELL; DRUG EFFECT; DRUG RESISTANCE; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; PHOTOCHEMOTHERAPY; PHYSIOLOGY; PROTO ONCOGENE;

ANIMALS; APOPTOSIS; CHO CELLS; CRICETINAE; DRUG RESISTANCE; GENE EXPRESSION; GENES, BCL-2; HUMANS; PHOTOCHEMOTHERAPY; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSFECTION;

EID: 0030294833     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1996.tb01845.x     Document Type: Article

References (46)

1. Dougherty, T. J. and S. L. Marcus (1992) Photodynamic therapy. Eur. J. Cancer 28A, 1734-1742.
2. Pass, H. P. (1993) Photodynamic therapy in oncology: mechanisms and clinical use. J. Natl. Cancer Inst. 85, 443-456.
3. Henderson, B. W. and T. J. Dougherty (1992) How does photodynamic therapy work? Photochem. Photobiol. 55, 145-147.
4. Rosenthal, I. (1991) Phthalocyanines as photodynamic sensitizers. Photochem. Photobiol. 53, 859-870.
5. Gomer, C. J., N. Rucker and A. L. Murphree (1988) Differential cell photosensitivity following porphyrin photodynamic therapy. Cancer Res. 48, 4539-4542.
6. Evans, H. H., R. M. Rerko, J. Mencl, M. E. Clay, A. R. Antunez and N. L. Oleinick (1989) Cytotoxic and mutagenic effects of the photodynamic action of chloroaluminum phthalocyanine and visible light in L5178Y cells. Photochem. Photobiol. 49, 43-47.
7. Kessel, D. (1989) Probing modes of multi-drug resistance via photodynamic effects of anthrapyrazoles. In Anticancer Drugs, Vol. 191 (Edited by H. Tapiero, J. Roberts and T. J. Lampidis), pp. 223-232. Colloque INSERM John Libbey Eurotext Ltd., Paris, France.
8. Gomer, C. J., N. Rucker and S. Wong (1990) Porphyrin photosensitivity in cell lines expressing a heat-resistant phenotype. Cancer Res. 50, 5365-5368.
9. Kessel, D. and C. Erickson (1992) Porphyrin photosensitization of multi-drug resistant cell types. Photochem. Photobiol. 55, 397-399.
10. Dellinger, M., G. Moreno, C. Salet, H. Tapiero and T. J. Lampidis (1992) Cytotoxic and photodynamic effects of Photofrin® on sensitive and multi-drug-resistant Friend leukemia cells. Int. J. Radiat. Biol. 62, 735-741.
11. Hagan, M. P., D. P. Dodgen and J. Z. Beer (1988) Impaired repair of UVC-induced DNA damage in L5178Y-R cells: sedimentation studies with the use of 5′-bromodeoxyuridine photolysis. Photochem. Photobiol. 47, 815-821.
12. Szumiel, I., D. Wlodek and K. J. Johanson (1988) Impaired repair of UVC-induced DNA damage in L5178Y-R cells: DNA unwinding studies with the use of 1-β-D-arabinosyl cytosine. Photochem. Photobiol. 48, 201-204.
13. Beer, J. Z., I. Szumiel and M. Walicka (1973) Cross-sensitivities to UV-light and X-rays of two strains of murine lymphoma L5178Y cells in vitro. Stud. Biophys. (Berlin) 36/37, 175-182.
14. Wlodek, D. and W. H. Hittelman (1987) The repair of double-strand DNA breaks correlates with radiosensitivity of L5178Y-S and L5178Y-R cells. Radiat. Res. 112, 146-155.
15. Evans, H. H., M. Ricanati and M. F. Horng (1987) Deficiency in DNA repair in mouse lymphoma strain L5178Y-S. Proc. Natl. Acad. Sci. USA 84, 7562-7566.
16. Singh, G., B. C. Wilson, S. M. Sharkey, G. P. Browman and P. Deschamps (1991) Resistance to photodynamic therapy in radiation induced fibrosarcoma-1 and Chinese hamster ovary-multi-drug resistant cells in vitro. Photochem. Photobiol. 54, 307-312.
17. Luna, M. C. and C. J. Gomer (1991) Isolation and initial characterization of mouse tumor cells resistant to porphyrin-mediated photodynamic therapy. Cancer Res. 51, 4243-4249.
18. Agarwal, M. L., M. E. Clay, E. J. Harvey, H. H. Evans, A. R. Antunez and N. L. Oleinick (1991) Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells. Cancer Res. 51, 5993-5996.
19. Oleinick, N. L., M. L. Agarwal, N. A. Berger, S. Berger, M. F. Cheng, S. Chatterjee, J. He, M. E. Kenney, H. E. Larkin, H. Mukhtar, B. D. Rihter and S. I. A. Zaidi (1993) Signal transduction and metabolic changes during tumor cell apoptosis following phthalocyanine-sensitized photodynamic therapy. In Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy II, (Edited by T. J. Dougherty), Proc. SPIE 1881, 252-261.
20. Wyllie, A. H., J. F. R. Kerr and A. R. Currie (1980) Cell death: the significance of apoptosis. Int. Rev. Cytol. 68, 251-306.
21. Williams, G. T. and C. A. Smith (1993) Molecular regulation of apoptosis: genetic control of cell death. Cell 74, 777-779.
22. Reed, J. C. (1994) Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124, 1-6.
23. Bissonnette, R. P., F. Echeverria, A. Mahboubi and D. R. Green (1992) Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 359, 552-554.
24. Krajewski, S., S. Tanaka, S. Takayaman, M. J. Schibler, W. Fenton and J. C. Reed (1993) Investigation of the subcellular distribution of the Bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res. 53, 4701-4714.
25. Hockenberry, D., Z. Oltvai, X.-M. Yin, C. Milliman and S. J. Korsmeyer (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251.
26. Kane, D. J., T. A. Sarafian, R. Anton, H. Hahn, E. B. Gralla, J. S. Valentine, T. Ord and S. E. Bredesen (1993) Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 262, 1274-1277.
27. 2+ fluxes. Proc. Natl. Acad. Sci. USA 91, 6569-6573.
28. Alderson, L. M., R. L. Castleberg, G. R. Harsh, 4th, D. N. Louis and J. W. Henson (1995) Human gliomas with wild-type p53 express bcl-2. Cancer Res. 55, 999-1001.
29. Wang, Y., L. Szekely, I. Okan, G. Klein and K. G. Wiman (1993) Wild-type p53-triggered apoptosis is inhibited by bcl-2 in a v-myc-induced T-cell lymphoma line. Oncogene 8, 3427-3431.
30. Davies, A. M. (1995) The Bcl-2 family of proteins, and the regulation of neuronal survival. Trends Neurosci. 18, 355-358.
31. Hashimoto, H., S. Chatterjee and N. A. Berger (1995) Inhibition of etoposide (VP-16)-induced DNA recombination and mutant frequency by Bcl-2 protein overexpression. Cancer Res. 55, 4029-4035.
32. Oleinick, N. L., A. R. Antunez, M. E. Clay, B. D. Rihter and M. E. Kenney (1993) New phthalocyanine photosensitizers for photodynamic therapy. Photochem. Photobiol. 57, 242-247.
33. Li, X., F. Traganos, M. R. Melamed and Z. Darzynkiewicz (1995) Single step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation. Cytometry 20, 172-180.
34. Walker, P. R., L. Kokleva, J. LeBlanc and M. Sikorska (1993) Detection of initial stages of DNA fragmentation in apoptosis. Biotechniques 15, 1032-1040.
35. Hengartner, M. O. and H. R. Horvitz (1994) C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76, 665-676.
36. Vaux, D. L., I. L. Weissman and S. K. Kim (1992) Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science 258, 1955-1957.
37. Vaux, D. L. (1993) Toward an understanding of the molecular mechanisms of physiological cell death. Proc. Natl. Acad. Sci. USA 90, 786-789.
38. Stewart, B. W. (1994) Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators. J. Natl. Cancer Inst. 86, 1286-1296.
39. L and Bcl-2, displaces Bax and promotes cell death. Cell 80, 285-291.
40. Oltvai, Z. N., C. L. Milliman and S. J. Korsmeyer (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.
41. Agarwal, M. L., H. E. Larkin, S. I. A. Zaidi, H. Mukhtar and N. L. Oleinick (1993) Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma cells. Cancer Res. 53, 5897-5902.
42. Ben-Hur, E. and T. M. A. R. Dubbelman (1993) Cytoplasmic free calcium changes as a trigger mechanism in the response of cells to photosensitization. Photochem. Photobiol. 58, 890-894.
43. Ramakrishnan, N., N. L. Oleinick, M. E. Clay, M.-F. Horng, A. R. Antunez and H. H. Evans (1989) DNA lesions and DNA degradation in mouse lymphoma L5178Y cells after photodynamic treatment sensitized by chloroaluminum phthalocyanine. Photochem. Photobiol. 53, 859-870.
44. Evans, H. H., M. Ricanati, M. F. Horng and J. Mencl (1989) Relationship between topoisomerase II and radiosensitivity in mouse L5178Y lymphoma strains. Mutat. Res. 217, 53-63.
45. Sharkey, S. M., B. C. Wilson, R. Moorehead and G. Singh (1993) Mitochondrial alterations in photodynamic therapy-resistant cells. Cancer Res. 53, 4994-4999.
46. Luna, M. C., A. Ferrario, N. Rucker and C. J. Gomer (1995) Decreased expression and function of α-2 macroglobulin receptor/low density lipoprotein receptor-related protein in photodynamic therapy-resistant mouse tumor cells. Cancer Res. 55, 1820-1823.