메뉴 건너뛰기




Volumn 10, Issue 4, 1999, Pages 947-959

Taxol suppresses dynamics of individual microtubules in living human tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

PACLITAXEL;

EID: 0032933622     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.10.4.947     Document Type: Article
Times cited : (491)

References (61)
  • 1
    • 0030048731 scopus 로고    scopus 로고
    • Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules
    • Belmont, L.D., and Mitchison, T.J. (1996). Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules. Cell 84, 623-631.
    • (1996) Cell , vol.84 , pp. 623-631
    • Belmont, L.D.1    Mitchison, T.J.2
  • 3
    • 0029913172 scopus 로고    scopus 로고
    • Taxol-induced apoptosis and phosphorylation of bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway
    • Blagosklonny, M.V., Schulte, T., Nguyen, P., Trepel, J., and Neckers, L. (1996). Taxol-induced apoptosis and phosphorylation of bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Res. 56, 1851-1854.
    • (1996) Cancer Res. , vol.56 , pp. 1851-1854
    • Blagosklonny, M.V.1    Schulte, T.2    Nguyen, P.3    Trepel, J.4    Neckers, L.5
  • 4
    • 0027936036 scopus 로고
    • How taxol modulates microtubule disassembly
    • Caplow, M., Shanks, J., and Ruhlen, R. (1994). How taxol modulates microtubule disassembly. Biochemistry 269, 23399-23402.
    • (1994) Biochemistry , vol.269 , pp. 23399-23402
    • Caplow, M.1    Shanks, J.2    Ruhlen, R.3
  • 5
    • 0024202112 scopus 로고
    • Real-time observations of microtubule dynamic instability in living cells
    • Cassimeris, L., Pryer, N.K., and Salmon, E.D. (1988). Real-time observations of microtubule dynamic instability in living cells. J. Cell Biol. 107, 2223-2231.
    • (1988) J. Cell Biol. , vol.107 , pp. 2223-2231
    • Cassimeris, L.1    Pryer, N.K.2    Salmon, E.D.3
  • 6
    • 0017276478 scopus 로고
    • The effects of methyl [5-(2-thienylcarbonyl)-1H-benzimadazol-2-yl]carbamate(R 17934; NSC 238159), a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro
    • DeBrabander, M.J., Van de Veire, R.M.L., Aerts, F.E.M., Borgers, M., and Janssen, P.A.J. (1976). The effects of methyl [5-(2-thienylcarbonyl)-1H-benzimadazol-2-yl]carbamate(R 17934; NSC 238159), a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro. Cancer Res. 36, 905-916.
    • (1976) Cancer Res. , vol.36 , pp. 905-916
    • DeBrabander, M.J.1    Van De Veire, R.M.L.2    Aerts, F.E.M.3    Borgers, M.4    Janssen, P.A.J.5
  • 7
    • 0028908695 scopus 로고
    • Substoichiometric binding of taxol suppresses microtubule dynamics
    • Derry, W., B., Wilson, L., and Jordan, M.A. (1995). Substoichiometric binding of taxol suppresses microtubule dynamics. Biochemistry 34, 2203-2211.
    • (1995) Biochemistry , vol.34 , pp. 2203-2211
    • Derry, W.B.1    Wilson, L.2    Jordan, M.A.3
  • 8
    • 0032520944 scopus 로고    scopus 로고
    • Low potency of taxol at microtubule minus ends: Implication for its antimitotic and therapeutic mechanism
    • Derry, W.B., Wilson, L., and Jordan, M.A. (1998). Low potency of taxol at microtubule minus ends: implication for its antimitotic and therapeutic mechanism. Cancer Res. 58, 1177-1184.
    • (1998) Cancer Res. , vol.58 , pp. 1177-1184
    • Derry, W.B.1    Wilson, L.2    Jordan, M.A.3
  • 9
    • 0030940117 scopus 로고    scopus 로고
    • Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified β-tubulin isotypes
    • Derry, W.B., Wilson, L., Khan, I.A., Luduena, R.F., and Jordan, M.A. (1997). Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified β-tubulin isotypes. Biochemistry 36, 3554-3562.
    • (1997) Biochemistry , vol.36 , pp. 3554-3562
    • Derry, W.B.1    Wilson, L.2    Khan, I.A.3    Luduena, R.F.4    Jordan, M.A.5
  • 10
  • 11
    • 0028924141 scopus 로고
    • Modulation of microtubule dynamic instability in vivo by brain microtubule associated proteins
    • Dhamodharan, R.I., and Wadsworth, P. (1995). Modulation of microtubule dynamic instability in vivo by brain microtubule associated proteins. J. Cell Sci. 108, 1679-1689.
    • (1995) J. Cell Sci. , vol.108 , pp. 1679-1689
    • Dhamodharan, R.I.1    Wadsworth, P.2
  • 12
    • 0027467778 scopus 로고
    • Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: Reversibility, ligand stoichiometry, and competition
    • Diaz, J.F., and Andreu, J.M. (1993). Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: reversibility, ligand stoichiometry, and competition. Biochemistry 32, 2747-2755.
    • (1993) Biochemistry , vol.32 , pp. 2747-2755
    • Diaz, J.F.1    Andreu, J.M.2
  • 14
    • 0031035693 scopus 로고    scopus 로고
    • Bcl2 is the guardian of microtubule integrity
    • Haldar, S., Basu, A., and Croce, C.M. (1997). Bcl2 is the guardian of microtubule integrity. Cancer Res. 57, 229-233.
    • (1997) Cancer Res. , vol.57 , pp. 229-233
    • Haldar, S.1    Basu, A.2    Croce, C.M.3
  • 15
    • 0025153023 scopus 로고
    • Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: Direct visualization in live newt cells
    • Hayden, J.J., Bowser, S.S., and Rieder, C. (1990). Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt cells. J. Cell Biol. 111, 1039-1045.
    • (1990) J. Cell Biol. , vol.111 , pp. 1039-1045
    • Hayden, J.J.1    Bowser, S.S.2    Rieder, C.3
  • 16
    • 0030968633 scopus 로고    scopus 로고
    • The microtubule-destabilizing activity of metablastin (p19) is controlled by phosphorylation
    • Horwitz, S., Shen, H., He, L., Dittmar, P., Neef, R., Chen, J., and Schubart, U. (1997). The microtubule-destabilizing activity of metablastin (p19) is controlled by phosphorylation. J. Biol. Chem. 272, 8129-8132.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8129-8132
    • Horwitz, S.1    Shen, H.2    He, L.3    Dittmar, P.4    Neef, R.5    Chen, J.6    Schubart, U.7
  • 17
    • 0026516994 scopus 로고
    • Mechanism of action of taxol
    • Horwitz, S.B. (1992). Mechanism of action of taxol. Trends Pharmacol. Sci. 13, 134-136.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 134-136
    • Horwitz, S.B.1
  • 18
    • 0023863085 scopus 로고
    • Linkages between the effects of taxol, colchicine, and GTP on tubulin polymerization
    • Howard, W.D., and Timasheff, S.N. (1988). Linkages between the effects of taxol, colchicine, and GTP on tubulin polymerization. J. Biol. Chem. 263, 1342-1346.
    • (1988) J. Biol. Chem. , vol.263 , pp. 1342-1346
    • Howard, W.D.1    Timasheff, S.N.2
  • 19
    • 0026643589 scopus 로고
    • Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis
    • Jordan, M.A., Thrower, D., and Wilson, L. (1992). Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. J. Cell Sci. 102, 401-416.
    • (1992) J. Cell Sci. , vol.102 , pp. 401-416
    • Jordan, M.A.1    Thrower, D.2    Wilson, L.3
  • 20
    • 0027360552 scopus 로고
    • Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
    • Jordan, M.A., Toso, R.J., Thrower, D., and Wilson, L. (1993). Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci USA 90, 9552-9556.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9552-9556
    • Jordan, M.A.1    Toso, R.J.2    Thrower, D.3    Wilson, L.4
  • 21
    • 0030020158 scopus 로고    scopus 로고
    • Mitotic block induced in hela cells by low concentrations of paclitaxel (taxol) results in abnormal mitotic exit and apoptotic cell death
    • Jordan, M.A., Wendell, K.L., Gardiner, S., Derry, W.B., Copp, H., and Wilson, L. (1996). Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res. 56, 816-825.
    • (1996) Cancer Res. , vol.56 , pp. 816-825
    • Jordan, M.A.1    Wendell, K.L.2    Gardiner, S.3    Derry, W.B.4    Copp, H.5    Wilson, L.6
  • 22
    • 0032006059 scopus 로고    scopus 로고
    • Microtubules and actin filaments: Dynamic targets for cancer chemotherapy
    • Jordan, M.A., and Wilson, L. (1998a). Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr. Opin. Cell Biol. 10, 123-130.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 123-130
    • Jordan, M.A.1    Wilson, L.2
  • 23
    • 0032621410 scopus 로고    scopus 로고
    • The use and action of drugs in analyzing mitosis
    • ed. C.L. Rieder, San Diego: Academic Press
    • Jordan, M.A., and Wilson, L. (1998b). The use and action of drugs in analyzing mitosis. In: Methods in Cell Biology, vol. 61, Mitosis and Meiosis, ed. C.L. Rieder, San Diego: Academic Press, 267-295.
    • (1998) Methods in Cell Biology, Vol. 61, Mitosis and Meiosis , vol.61 , pp. 267-295
    • Jordan, M.A.1    Wilson, L.2
  • 24
    • 0019805521 scopus 로고
    • Taxol-induced polymerization of purified tubulin
    • Kumar, N. (1981). Taxol-induced polymerization of purified tubulin. J. Biol. Chem. 256, 10435-10441.
    • (1981) J. Biol. Chem. , vol.256 , pp. 10435-10441
    • Kumar, N.1
  • 25
    • 0028872743 scopus 로고
    • Mitotic forces control a cell-cycle checkpoint
    • Li, X., and Nicklas, R.B. (1995). Mitotic forces control a cell-cycle checkpoint. Nature 373, 630-632.
    • (1995) Nature , vol.373 , pp. 630-632
    • Li, X.1    Nicklas, R.B.2
  • 26
    • 0030709242 scopus 로고    scopus 로고
    • Multiple forms of tubulin: Different gene products and covalent modifications
    • Luduena, R.F. (1998). Multiple forms of tubulin: different gene products and covalent modifications. Int. Rev. Cytol. 178, 207-275.
    • (1998) Int. Rev. Cytol. , vol.178 , pp. 207-275
    • Luduena, R.F.1
  • 27
    • 0017835961 scopus 로고
    • Opposite end assembly and disassembly of microtubules at steady state in vitro
    • Margolis, R.L., and Wilson, L. (1978). Opposite end assembly and disassembly of microtubules at steady state in vitro. Cell 13, 1-8.
    • (1978) Cell , vol.13 , pp. 1-8
    • Margolis, R.L.1    Wilson, L.2
  • 28
    • 0030981660 scopus 로고    scopus 로고
    • Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset
    • McEwen, B., Heagle, A., Cassels, G., Buttle, K., and Rieder, C. (1997). Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset. J. Cell Biol. 137, 1567-1580.
    • (1997) J. Cell Biol. , vol.137 , pp. 1567-1580
    • McEwen, B.1    Heagle, A.2    Cassels, G.3    Buttle, K.4    Rieder, C.5
  • 30
    • 0024369644 scopus 로고
    • Poleward microtubule flux in the mitotic spindle; evidence from photoactivation of fluorescence
    • Mitchison, T.J. (1989). Poleward microtubule flux in the mitotic spindle; evidence from photoactivation of fluorescence. J. Cell Biol. 109, 637-652.
    • (1989) J. Cell Biol. , vol.109 , pp. 637-652
    • Mitchison, T.J.1
  • 31
    • 0021686169 scopus 로고
    • Dynamic instability of microtubule growth
    • Mitchison, T.J., and Kirschner, M. (1984). Dynamic instability of microtubule growth. Nature 312, 237-242.
    • (1984) Nature , vol.312 , pp. 237-242
    • Mitchison, T.J.1    Kirschner, M.2
  • 32
    • 0032482920 scopus 로고    scopus 로고
    • Antiproliferative mechanism of action of cryptophycin-52: Kinetic stabilization of microtubule dynamics by high affinity binding of microtubule ends
    • Panda, D., DeLuca, K., Williams, D., Jordan, M.A., and Wilson, L. (1998). Antiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high affinity binding of microtubule ends. Proc. Natl. Acad. Sci. USA 95, 9313-9318.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9313-9318
    • Panda, D.1    DeLuca, K.2    Williams, D.3    Jordan, M.A.4    Wilson, L.5
  • 33
    • 0019859353 scopus 로고
    • Taxol binds to polymerized tubulin in vitro
    • Parness, J., and Horwitz, S.B. (1981). Taxol binds to polymerized tubulin in vitro. J. Cell Biol. 91, 479-487.
    • (1981) J. Cell Biol. , vol.91 , pp. 479-487
    • Parness, J.1    Horwitz, S.B.2
  • 34
    • 0025688199 scopus 로고
    • Microtubules are stabilized in confluent epithelial cells but not in fibroblasts
    • Pepperkok, R., Bre, M.H., Davoust, J., and Kreis, T.E. (1990). Microtubules are stabilized in confluent epithelial cells but not in fibroblasts. J. Cell Biol. 111, 3003-3012.
    • (1990) J. Cell Biol. , vol.111 , pp. 3003-3012
    • Pepperkok, R.1    Bre, M.H.2    Davoust, J.3    Kreis, T.E.4
  • 35
    • 0027942033 scopus 로고
    • Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle
    • Rieder, C., Schultz, A., Cole, R., and Sluder, G. (1994). Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle. J. Cell Biol. 127, 1301-1310.
    • (1994) J. Cell Biol. , vol.127 , pp. 1301-1310
    • Rieder, C.1    Schultz, A.2    Cole, R.3    Sluder, G.4
  • 36
    • 0029160299 scopus 로고
    • The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
    • Rieder, C.L., Cole, R.W., Khodjakov, A., and Sluder, G. (1995). The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores. J. Cell Biol. 130, 941-948.
    • (1995) J. Cell Biol. , vol.130 , pp. 941-948
    • Rieder, C.L.1    Cole, R.W.2    Khodjakov, A.3    Sluder, G.4
  • 37
    • 0031013546 scopus 로고    scopus 로고
    • Microtubule treadmilling in vivo
    • Rodionov, V.I., and Borisy, G.G. (1997). Microtubule treadmilling in vivo. Science 275, 215-218.
    • (1997) Science , vol.275 , pp. 215-218
    • Rodionov, V.I.1    Borisy, G.G.2
  • 38
    • 0001468493 scopus 로고
    • A cellophane strip technique for culturing tissue in multipurpose culture chambers
    • Rose, G.G., Pomerat, C.M., Shindler, T., and Trunnell, J. (1958). A cellophane strip technique for culturing tissue in multipurpose culture chambers. J. Biophys. Biochem. Cytol. 4, 761-764.
    • (1958) J. Biophys. Biochem. Cytol. , vol.4 , pp. 761-764
    • Rose, G.G.1    Pomerat, C.M.2    Shindler, T.3    Trunnell, J.4
  • 39
    • 0031040149 scopus 로고    scopus 로고
    • The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents
    • Rowinsky, E. (1997). The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents. Annu. Rev. Med. 48, 353-374.
    • (1997) Annu. Rev. Med. , vol.48 , pp. 353-374
    • Rowinsky, E.1
  • 41
    • 0023809123 scopus 로고
    • Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol
    • Rowinsky, E.K., Donehower, R.C., Jones, R.J., and Tucker, R.W. (1988). Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol. Cancer Res. 49, 4093-4100.
    • (1988) Cancer Res. , vol.49 , pp. 4093-4100
    • Rowinsky, E.K.1    Donehower, R.C.2    Jones, R.J.3    Tucker, R.W.4
  • 42
    • 0023782317 scopus 로고
    • Detection of single fluorescent microtubules and methods for determining their dynamics in living cells
    • Sammak, P.J., and Borisy, G.G. (1988). Detection of single fluorescent microtubules and methods for determining their dynamics in living cells. Cell Motil. Cytoskeleton 10, 237-245.
    • (1988) Cell Motil. Cytoskeleton , vol.10 , pp. 237-245
    • Sammak, P.J.1    Borisy, G.G.2
  • 44
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by taxol
    • Schiff, P.B., Fant, J., and Horwitz, S.B. (1979). Promotion of microtubule assembly in vitro by taxol. Nature 277, 665-667.
    • (1979) Nature , vol.277 , pp. 665-667
    • Schiff, P.B.1    Fant, J.2    Horwitz, S.B.3
  • 45
    • 0000297058 scopus 로고
    • Taxol stabilizes microtubules in mouse fibroblast cells
    • Schiff, P.B., and Horwitz, S.B. (1980). Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl. Acad. Sci. USA 77, 1561-1565.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 1561-1565
    • Schiff, P.B.1    Horwitz, S.B.2
  • 46
    • 0023788884 scopus 로고
    • New features of microtubule behavior observed in vivo
    • Schulze, E., and Kirschner, M. (1988). New features of microtubule behavior observed in vivo. Nature 334, 356-359.
    • (1988) Nature , vol.334 , pp. 356-359
    • Schulze, E.1    Kirschner, M.2
  • 47
    • 0027458626 scopus 로고
    • Observation and quantification of individual microtubule behavior in vivo: Microtubule dynamics are cell-type specific
    • Shelden, E., and Wadsworth, P. (1993). Observation and quantification of individual microtubule behavior in vivo: microtubule dynamics are cell-type specific. J. Cell Biol. 120, 935-945.
    • (1993) J. Cell Biol. , vol.120 , pp. 935-945
    • Shelden, E.1    Wadsworth, P.2
  • 48
    • 0029737896 scopus 로고    scopus 로고
    • Stimulation of microtubule dynamic turnover in living cells treated with okadaic acid
    • Shelden, E., and Wadsworth, P. (1996). Stimulation of microtubule dynamic turnover in living cells treated with okadaic acid. Cell Motil. Cytoskeleton 35, 24-34.
    • (1996) Cell Motil. Cytoskeleton , vol.35 , pp. 24-34
    • Shelden, E.1    Wadsworth, P.2
  • 51
    • 0030920202 scopus 로고    scopus 로고
    • Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro
    • Vasquez, R.J., Howell, B., Yvon, A.-M.C., Wadsworth, P., and Cassimeris, L. (1997). Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol. Biol. Cell 8, 973-985.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 973-985
    • Vasquez, R.J.1    Howell, B.2    Yvon, A.-M.C.3    Wadsworth, P.4    Cassimeris, L.5
  • 52
    • 0024094432 scopus 로고
    • Dynamic instability of individual microtubules analyzed by video light microscopy: Rate constants and transition frequencies
    • Walker, R.A., O'Brien, E.T., Pryer, N.K., Soboeiro, M.F., Voter, W.A., Erickson, H., and Salmon, E.D. (1988). Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies. J. Cell Biol. 107, 1437-1448.
    • (1988) J. Cell Biol. , vol.107 , pp. 1437-1448
    • Walker, R.A.1    O'Brien, E.T.2    Pryer, N.K.3    Soboeiro, M.F.4    Voter, W.A.5    Erickson, H.6    Salmon, E.D.7
  • 54
    • 0031172760 scopus 로고    scopus 로고
    • Microtubule dynamics: Treadmilling comes around again
    • Waterman-Storer, C., and Salmon, E.D. (1997). Microtubule dynamics: treadmilling comes around again. Curr. Biol. 7, 369-372.
    • (1997) Curr. Biol. , vol.7 , pp. 369-372
    • Waterman-Storer, C.1    Salmon, E.D.2
  • 55
    • 0032101688 scopus 로고    scopus 로고
    • Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
    • Waters, J.C., Chen, R.H., Murray, A.W., Salmon, E.D. (1998). Localization of Mad2 to kinetochores depends on microtubule attachment, not tension. J. Cell Biol. 141, 1181-1191.
    • (1998) J. Cell Biol. , vol.141 , pp. 1181-1191
    • Waters, J.C.1    Chen, R.H.2    Murray, A.W.3    Salmon, E.D.4
  • 56
    • 0027462041 scopus 로고
    • Mitotic block in HeLa cells by vinblastine: Ultrastructural changes in kinetochoremicrotubule attachment and in centrosomes
    • Wendell, K.L., Wilson, L., and Jordan, M.A. (1993). Mitotic block in HeLa cells by vinblastine: ultrastructural changes in kinetochoremicrotubule attachment and in centrosomes. J. Cell Sci. 104, 261-274.
    • (1993) J. Cell Sci. , vol.104 , pp. 261-274
    • Wendell, K.L.1    Wilson, L.2    Jordan, M.A.3
  • 57
    • 0029360519 scopus 로고
    • Microtubule dynamics: Taking aim at a moving target
    • Wilson, L., and Jordan, M.A. (1995). Microtubule dynamics: taking aim at a moving target. Chem. Biol. 2, 569-573.
    • (1995) Chem. Biol. , vol.2 , pp. 569-573
    • Wilson, L.1    Jordan, M.A.2
  • 58
    • 0026766576 scopus 로고
    • Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening
    • Wu, L., et al. (1992). Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening. Cancer Res. 52, 3029-3034.
    • (1992) Cancer Res. , vol.52 , pp. 3029-3034
    • Wu, L.1
  • 59
    • 0000885332 scopus 로고    scopus 로고
    • Noncentrosomal microtubule formation and measurement of minus end microtubule dynamics in A498 cells
    • Yvon, A.M., and Wadsworth, P. (1997). Noncentrosomal microtubule formation and measurement of minus end microtubule dynamics in A498 cells. J. Cell Sci. 110, 2391-2401.
    • (1997) J. Cell Sci. , vol.110 , pp. 2391-2401
    • Yvon, A.M.1    Wadsworth, P.2
  • 60
    • 0029662197 scopus 로고    scopus 로고
    • Microtubule dynamics at the G2/M transition: Abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis
    • Zhai, Y., Kronebusch, P.J., Simon, P.M., and Borisy, G.G. (1996). Microtubule dynamics at the G2/M transition: abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis. J. Cell Biol. 135, 201-214.
    • (1996) J. Cell Biol. , vol.135 , pp. 201-214
    • Zhai, Y.1    Kronebusch, P.J.2    Simon, P.M.3    Borisy, G.G.4
  • 61
    • 0018966230 scopus 로고
    • Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor nocodazole
    • Zieve, G.W., Turnbull, D., Mullins, J.M., and McIntosh, J.R. (1980). Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor nocodazole. Exp. Cell Res. 126, 397-405.
    • (1980) Exp. Cell Res. , vol.126 , pp. 397-405
    • Zieve, G.W.1    Turnbull, D.2    Mullins, J.M.3    McIntosh, J.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.