메뉴 건너뛰기




Volumn 373, Issue 1, 1997, Pages 87-97

The tumor suppressor p53 modifies mutational processes in a human lymphoblastoid cell line

Author keywords

Altered p53; Apoptosis; DNA recombination; Human lymphoblast; Radiation mutagenesis

Indexed keywords

PROTEIN P53;

EID: 0031016093     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(96)00193-5     Document Type: Article
Times cited : (35)

References (65)
  • 1
    • 0026561595 scopus 로고
    • A comparison of induced mutation at homologous alleles of the tk locus in human cells. II. Molecular analysis of mutants
    • Amundson, S.A. and H.L. Liber (1992) A comparison of induced mutation at homologous alleles of the tk locus in human cells. II. Molecular analysis of mutants, Mutation Res., 267, 89-95.
    • (1992) Mutation Res. , vol.267 , pp. 89-95
    • Amundson, S.A.1    Liber, H.L.2
  • 2
    • 0027410190 scopus 로고
    • Different cytotoxic and mutagenic responses induced by X-rays in two human lymphoblastoid cell lines derived from a single donor
    • Amundson, S.A., F. Xia, K. Wolfson and H.L. Liber (1993) Different cytotoxic and mutagenic responses induced by X-rays in two human lymphoblastoid cell lines derived from a single donor, Mutation Res., 286, 233-241.
    • (1993) Mutation Res. , vol.286 , pp. 233-241
    • Amundson, S.A.1    Xia, F.2    Wolfson, K.3    Liber, H.L.4
  • 5
    • 0028228913 scopus 로고
    • Human p53 directs DNA strand reassociation and is photolabelled by 8-azido ATP
    • Brain, R. and J.R. Jenkins (1994) Human p53 directs DNA strand reassociation and is photolabelled by 8-azido ATP, Oncogene, 9, 1775-1780.
    • (1994) Oncogene , vol.9 , pp. 1775-1780
    • Brain, R.1    Jenkins, J.R.2
  • 6
    • 0028070989 scopus 로고
    • p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles, C., A. Helmberg and M. Karin (1994) p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes, Nature, 370, 220-223.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 8
    • 0028899480 scopus 로고
    • Separate domains of p21 involved in the inhibition of CdK kinase and PCNA
    • Chen, J., P.K. Jackson, M.W. Kirschner and A. Dutta (1995) Separate domains of p21 involved in the inhibition of CdK kinase and PCNA, Nature, 374, 386-388.
    • (1995) Nature , vol.374 , pp. 386-388
    • Chen, J.1    Jackson, P.K.2    Kirschner, M.W.3    Dutta, A.4
  • 10
    • 0025024469 scopus 로고
    • Presence of a potent transcription activating sequence in the p53 protein
    • Fields, S. and S.K. Jang (1990) Presence of a potent transcription activating sequence in the p53 protein, Science, 249, 1046-1049.
    • (1990) Science , vol.249 , pp. 1046-1049
    • Fields, S.1    Jang, S.K.2
  • 12
    • 0028071555 scopus 로고
    • Mutations in the tumor suppressor gene: clues to cancer etiology and molecular pathogenesis
    • Greenblatt, M., W. Bennett, M. Hollstein and C. Harris (1994) Mutations in the tumor suppressor gene: clues to cancer etiology and molecular pathogenesis, Cancer Res., 54, 4855-4878.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.1    Bennett, W.2    Hollstein, M.3    Harris, C.4
  • 13
    • 0029264061 scopus 로고
    • The dominating effect of mutant p53
    • Hann, B.C. and D.P. Lane (1995) The dominating effect of mutant p53, Nature Genet., 9, 221-222.
    • (1995) Nature Genet. , vol.9 , pp. 221-222
    • Hann, B.C.1    Lane, D.P.2
  • 15
    • 0029029938 scopus 로고
    • p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells
    • Harvey, P.A., J. Yuan, L. Hedrick, K.R. Cho and P.M. Glazer (1995) p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells, Cancer Res., 55, 4420-4424.
    • (1995) Cancer Res. , vol.55 , pp. 4420-4424
    • Harvey, P.A.1    Yuan, J.2    Hedrick, L.3    Cho, K.R.4    Glazer, P.M.5
  • 17
    • 0024410226 scopus 로고
    • Hypobetalipoproteinaemia due to an apolipoprotein B gene exon 21 deletion derived by alu-alu recombination
    • Huang, L.-S., M. Ripps, S. Korman, R. Deckelbaum and J. Breslow (1989) Hypobetalipoproteinaemia due to an apolipoprotein B gene exon 21 deletion derived by alu-alu recombination, J. Biol. Chem., 264, 11394-11400.
    • (1989) J. Biol. Chem. , vol.264 , pp. 11394-11400
    • Huang, L.-S.1    Ripps, M.2    Korman, S.3    Deckelbaum, R.4    Breslow, J.5
  • 18
    • 0029055808 scopus 로고
    • Activation of p53 sequence-specific DNA Binding by short single strands of DNA requires the p53 C-terminus
    • Jayaraman, L. and C. Prives (1995) Activation of p53 sequence-specific DNA Binding by short single strands of DNA requires the p53 C-terminus, Cell, 81, 1021-1029.
    • (1995) Cell , vol.81 , pp. 1021-1029
    • Jayaraman, L.1    Prives, C.2
  • 19
    • 0026318356 scopus 로고
    • Participation of p53 protein in the cellular response to DNA damage
    • Kastan, M., O. Onyekere, D. Sidransky, B. Vogelstein and R. Craig (1991) Participation of p53 protein in the cellular response to DNA damage, Cancer Res., 51, 6304-6311.
    • (1991) Cancer Res. , vol.51 , pp. 6304-6311
    • Kastan, M.1    Onyekere, O.2    Sidransky, D.3    Vogelstein, B.4    Craig, R.5
  • 20
    • 0041985965 scopus 로고
    • High level of production of proteins in mammalian cells
    • in: J.K. Setlow (Ed.), Plenum Press, New York
    • Kaufman, R.J. (1987) High level of production of proteins in mammalian cells, in: J.K. Setlow (Ed.), Genetic Engineering: Principles and Methods, Plenum Press, New York, pp. 155-198.
    • (1987) Genetic Engineering: Principles and Methods , pp. 155-198
    • Kaufman, R.J.1
  • 21
    • 0025375266 scopus 로고
    • Vectors used for expression in mammalian cells
    • Kaufman, R.J. (1990) Vectors used for expression in mammalian cells, Methods Enzymol. 185, 487-511.
    • (1990) Methods Enzymol. , vol.185 , pp. 487-511
    • Kaufman, R.J.1
  • 25
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane, D. (1992) p53, guardian of the genome, Nature, 358, 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.1
  • 26
    • 0024493729 scopus 로고
    • A comparison of mutation induction at the tk and hprt loci in human lymphoblastoid cells; quantitative differences are due to an additional class of mutations at the autosomal tk locus
    • Liber, H.L., D.W. Yandell and J.B. Little (1989) A comparison of mutation induction at the tk and hprt loci in human lymphoblastoid cells; quantitative differences are due to an additional class of mutations at the autosomal tk locus, Mutation Res., 216, 9-17.
    • (1989) Mutation Res. , vol.216 , pp. 9-17
    • Liber, H.L.1    Yandell, D.W.2    Little, J.B.3
  • 27
    • 0026683328 scopus 로고
    • Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies
    • Lipkowitz, S., V.F. Garry and I.R. Kirsch (1992) Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies, Proc. Natl. Acad. Sci. USA, 89, 5301-5305.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5301-5305
    • Lipkowitz, S.1    Garry, V.F.2    Kirsch, I.R.3
  • 28
    • 0028990145 scopus 로고
    • Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status
    • Little, J., H. Nagasawa, P. Keng, Y. Yu and C. Li (1995) Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status, J. Biol. Chem., 270, 11033-11036.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11033-11036
    • Little, J.1    Nagasawa, H.2    Keng, P.3    Yu, Y.4    Li, C.5
  • 29
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone, L.R., A. White, J. Sprouse, E. Livanos, T. Jacks and T.D. Tlsty (1992) Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53, Cell, 70, 923-935.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 30
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S.W., E.M. Schmitt, S.W. Smith, B.A. Osborne and T. Jacks (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes, Nature, 362, 847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 32
    • 0027306104 scopus 로고
    • High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia
    • Meyn, M.S. (1993) High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia, Science, 260, 1327-1330.
    • (1993) Science , vol.260 , pp. 1327-1330
    • Meyn, M.S.1
  • 33
    • 0028916585 scopus 로고
    • A role for genomic instability in cellular radioresistance?
    • Morgan, W.F. and J.P. Murnane (1995) A role for genomic instability in cellular radioresistance?, Cancer Metastasis Rev., 14, 49-58.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 49-58
    • Morgan, W.F.1    Murnane, J.P.2
  • 34
    • 0027459104 scopus 로고
    • Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome break
    • Murnane, J.P. and L.C. Yu (1993) Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome break, Mol. Cell. Biol., 13, 977-983.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 977-983
    • Murnane, J.P.1    Yu, L.C.2
  • 35
    • 0028204160 scopus 로고
    • DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathway
    • Nelson, W. and M. Kastan (1994) DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathway, Mol. Cell. Biol., 14, 1815-1823.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1815-1823
    • Nelson, W.1    Kastan, M.2
  • 37
    • 0029097375 scopus 로고
    • Spectra of spontaneous and x-ray induced mutations at the hprt locus in related human lymphoblast cell lines that express wild-type or mutant p53
    • Phillips, E., F. Xia, K. Kelsey and H. Liber (1995) Spectra of spontaneous and x-ray induced mutations at the hprt locus in related human lymphoblast cell lines that express wild-type or mutant p53, Radiation Res., 143, 255-262.
    • (1995) Radiation Res. , vol.143 , pp. 255-262
    • Phillips, E.1    Xia, F.2    Kelsey, K.3    Liber, H.4
  • 39
    • 0027948119 scopus 로고
    • p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines
    • Radford, I. (1994) p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines, Int. J. Radiat. Biol., 66, 557-560.
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 557-560
    • Radford, I.1
  • 40
    • 0025193635 scopus 로고
    • Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
    • Raycroft, L., H. Wu and G. Lozano (1990) Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene, Science, 249, 1049-51.
    • (1990) Science , vol.249 , pp. 1049-1051
    • Raycroft, L.1    Wu, H.2    Lozano, G.3
  • 41
    • 0028980495 scopus 로고
    • p53 deficiency dose not affect the accumulation of point mutation in a transgene target
    • Sands, S., M. Suraokar, A. Sanchez, J. Marth and L. Donehower (1995) p53 deficiency dose not affect the accumulation of point mutation in a transgene target, Proc. Natl. Acad. Sci. USA, 92, 8517-8521.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8517-8521
    • Sands, S.1    Suraokar, M.2    Sanchez, A.3    Marth, J.4    Donehower, L.5
  • 42
    • 0344135033 scopus 로고
    • Gene transfer and expression protocols
    • in: E.J. Murray (Ed.), Humana Press, Clifton, NJ
    • Santerre, R., J. Walls and B. Grinnell (1993) Gene transfer and expression protocols, in: E.J. Murray (Ed.), Methods in Molecular Biology, Humana Press, Clifton, NJ, pp. 245-256.
    • (1993) Methods in Molecular Biology , pp. 245-256
    • Santerre, R.1    Walls, J.2    Grinnell, B.3
  • 43
    • 0028233970 scopus 로고
    • The nuclear tyrosine kinase c-abl negatively regulates cell growth
    • Sawyers, C.L., J. Mclaughlin, A. Goga, M. Havlik and O. Witte (1994) The nuclear tyrosine kinase c-abl negatively regulates cell growth, Cell, 77, 121-131.
    • (1994) Cell , vol.77 , pp. 121-131
    • Sawyers, C.L.1    McLaughlin, J.2    Goga, A.3    Havlik, M.4    Witte, O.5
  • 44
    • 0028980555 scopus 로고
    • Different sensitivity to the cell killing and chromosome mutation induction by gamma-rays in two human lymphoblastoid cell lines derived from a single donor: Possible role of apoptosis
    • Schwartz, J., R. Jordon, B. Sedita, M. Swenningson, J. Banath and P. Olive (1995) Different sensitivity to the cell killing and chromosome mutation induction by gamma-rays in two human lymphoblastoid cell lines derived from a single donor: possible role of apoptosis, Mutagenesis, 10, 227-233.
    • (1995) Mutagenesis , vol.10 , pp. 227-233
    • Schwartz, J.1    Jordon, R.2    Sedita, B.3    Swenningson, M.4    Banath, J.5    Olive, P.6
  • 45
    • 0028870394 scopus 로고
    • Genomic instability and the role of p53 mutation in cancer cells
    • Smith, M. and A.J. Fornace Jr. (1995) Genomic instability and the role of p53 mutation in cancer cells, Curr. Opin. Oncol., 7, 69-75.
    • (1995) Curr. Opin. Oncol. , vol.7 , pp. 69-75
    • Smith, M.1    Fornace A.J., Jr.2
  • 47
    • 0028919069 scopus 로고
    • Involvement of the p53 tumor suppressor in repair of UV-type DNA damage
    • Smith, M., I. Chen, Q. Zhan, P. O'Connor and A.J. Fornace, Jr. (1995) Involvement of the p53 tumor suppressor in repair of UV-type DNA damage, Oncogene, 10, 1053-1059.
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.1    Chen, I.2    Zhan, Q.3    O'Connor, P.4    Fornace A.J., Jr.5
  • 48
    • 0025648762 scopus 로고
    • Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
    • Srivastava, S., Z. Zou, K. Pirollo, W. Blattner and E. Chang (1990) Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome, Nature, 348, 747-749.
    • (1990) Nature , vol.348 , pp. 747-749
    • Srivastava, S.1    Zou, Z.2    Pirollo, K.3    Blattner, W.4    Chang, E.5
  • 49
    • 0024212653 scopus 로고
    • DNA binding properties of murine p53
    • Steinmeyer, K. and W. Deppert (1988) DNA binding properties of murine p53, Oncogene, 3, 501-507.
    • (1988) Oncogene , vol.3 , pp. 501-507
    • Steinmeyer, K.1    Deppert, W.2
  • 50
    • 0028916584 scopus 로고
    • Genomic instability due to germline p53 mutations drives preneoplastic progression toward cancer in human cells
    • Tainsky, M., F. Bischoff and L. Strong (1995) Genomic instability due to germline p53 mutations drives preneoplastic progression toward cancer in human cells, Cancer Metastasis Rev., 14, 43-48.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 43-48
    • Tainsky, M.1    Bischoff, F.2    Strong, L.3
  • 51
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau, S.N., G. Bern and D. Schaid (1993) Microsatellite instability in cancer of the proximal colon, Science, 260, 816-819.
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bern, G.2    Schaid, D.3
  • 53
    • 0028326952 scopus 로고
    • An evolutionary perspective on apoptosis
    • Vaux, D.L., G. Haecker and A. Strasser (1994) An evolutionary perspective on apoptosis, Cell, 76, 777-779.
    • (1994) Cell , vol.76 , pp. 777-779
    • Vaux, D.L.1    Haecker, G.2    Strasser, A.3
  • 54
    • 0001655748 scopus 로고
    • Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3
    • Wang, X., K. Forrester, H. Yeh, M. Feitelson, J. Gu and C. Harris (1994) Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3, Proc. Natl. Acad. Sci. USA, 91, 2230-2234.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2230-2234
    • Wang, X.1    Forrester, K.2    Yeh, H.3    Feitelson, M.4    Gu, J.5    Harris, C.6
  • 56
    • 0027587793 scopus 로고
    • Cell cycle checkpoints, genetic instability and cancer
    • Weinert, T. and D. Lydall (1993) Cell cycle checkpoints, genetic instability and cancer, Semi Cancer Biol., 4, 129-140.
    • (1993) Semi Cancer Biol. , vol.4 , pp. 129-140
    • Weinert, T.1    Lydall, D.2
  • 57
    • 0030068266 scopus 로고    scopus 로고
    • In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes
    • Wiesmuller, L., J. Gammenga and W. Deppert (1996) In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes, J. Virol., 70, 737-744.
    • (1996) J. Virol. , vol.70 , pp. 737-744
    • Wiesmuller, L.1    Gammenga, J.2    Deppert, W.3
  • 59
    • 0029436706 scopus 로고
    • Electroporation of human lymphoblastoid cells
    • in: J.A. Nickoloff (Ed.), Humana Press, Totowa, New Jersey
    • Xia, F. and H.L. Liber (1995) Electroporation of human lymphoblastoid cells, in: J.A. Nickoloff (Ed.), Animal Cell Electroporation and Electrofusion Protocols, Humana Press, Totowa, New Jersey, pp. 151-160.
    • (1995) Animal Cell Electroporation and Electrofusion Protocols , pp. 151-160
    • Xia, F.1    Liber, H.L.2
  • 60
    • 0028144964 scopus 로고
    • Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation
    • Xia, F., S.A. Amundson, J.A. Nickoloff and H.L. Liber (1994) Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation, Mol. Cell. Biol., 14, 5850-5857.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5850-5857
    • Xia, F.1    Amundson, S.A.2    Nickoloff, J.A.3    Liber, H.L.4
  • 61
    • 0028944890 scopus 로고
    • Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closed related human lymphoblast lines
    • Xia, F., X. Wang, Y.-H. Wang, N.-M. Tsang, D.W. Yandell, K.T. Kelsey and H.L. Liber (1995) Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closed related human lymphoblast lines, Cancer Res., 55, 12-15.
    • (1995) Cancer Res. , vol.55 , pp. 12-15
    • Xia, F.1    Wang, X.2    Wang, Y.-H.3    Tsang, N.-M.4    Yandell, D.W.5    Kelsey, K.T.6    Liber, H.L.7
  • 62
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin, Y., M.A. Tainsky, F.Z. Bischoff, L.C. Strong and G.M. Wahl (1992) Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles, Cell, 70, 937-948.
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 63
    • 0028787978 scopus 로고
    • Induction of p53 in mouse cells decreases mutagenesis by UV radiation
    • Yuan, J., T. Yeasky, P. Havre and P. Glazer (1995) Induction of p53 in mouse cells decreases mutagenesis by UV radiation, Carcinogenesis, 16, 2295-2300.
    • (1995) Carcinogenesis , vol.16 , pp. 2295-2300
    • Yuan, J.1    Yeasky, T.2    Havre, P.3    Glazer, P.4
  • 64
    • 0027275854 scopus 로고
    • Novel DNA binding of p53 mutants and their role in transcriptional activation
    • Zhang, W., W. Funk, W. Wright, J. Shay and A. Deisseroth (1993) Novel DNA binding of p53 mutants and their role in transcriptional activation, Oncogene, 8, 2555-2559.
    • (1993) Oncogene , vol.8 , pp. 2555-2559
    • Zhang, W.1    Funk, W.2    Wright, W.3    Shay, J.4    Deisseroth, A.5
  • 65
    • 0028986587 scopus 로고
    • The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status
    • Zhan, W., C. Denault, K. Loviscek, S. Walter, L. Geng and A. Vaughan (1995) The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status, Mutation Res., 346, 85-92.
    • (1995) Mutation Res. , vol.346 , pp. 85-92
    • Zhan, W.1    Denault, C.2    Loviscek, K.3    Walter, S.4    Geng, L.5    Vaughan, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.