Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor

Atherosclerosis

Volumn 154, Issue 3, 2001, Pages 625-632

  Botma, Gert Jan ^a   Verhoeven, Adrie J M ^a   Jansen, Hans ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Gene polymorphism; Hepatic lipase gene expression; Hepatic lipase promoter; Transcriptional regulation; Transient transfection; Upstream Stimulatory Factor

Indexed keywords

COMPLEMENTARY DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER TRIACYLGLYCEROL LIPASE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL STRAIN HEPG2; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; BASE SEQUENCE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIPASE; LIVER; PROMOTER REGIONS (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; UPSTREAM STIMULATORY FACTORS; VARIATION (GENETICS);

EID: 0035864637     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(00)00478-0     Document Type: Article

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