-
1
-
-
0023411990
-
Three-dimensional structure of a genetically engineered variant of porcine growth hormone
-
Abdel-Meguid, S.S., H.S. Shieh, W.W. Smith, H.E. Dayringer, B.N. Violand, and L.A. Bentle. 1987. Three-dimensional structure of a genetically engineered variant of porcine growth hormone. Proc. Natl. Acad. Sci. USA 84:6434-6437.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 6434-6437
-
-
Abdel-Meguid, S.S.1
Shieh, H.S.2
Smith, W.W.3
Dayringer, H.E.4
Violand, B.N.5
Bentle, L.A.6
-
2
-
-
0033554674
-
Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme
-
Aritomi, M., N. Kunishima, T. Okamoto, R. Kuroki, Y. Ota, and K. Morikawa. 1999. Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme. Nature 401:713-717.
-
(1999)
Nature
, vol.401
, pp. 713-717
-
-
Aritomi, M.1
Kunishima, N.2
Okamoto, T.3
Kuroki, R.4
Ota, Y.5
Morikawa, K.6
-
3
-
-
0025356737
-
Shared architecture of hormone binidng in type I and type II interferon receptors
-
Bazan, J.F. 1990. Shared architecture of hormone binidng in type I and type II interferon receptors. Cell 61:753-754.
-
(1990)
Cell
, vol.61
, pp. 753-754
-
-
Bazan, J.F.1
-
4
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan, J.F. 1990. Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl. Acad. Sci. USA 87:6934-413.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
5
-
-
0026763387
-
Unraveling the structure of IL-2
-
Bazan, J.F. 1992. Unraveling the structure of IL-2. Science 257:410-413.
-
(1992)
Science
, vol.257
, pp. 410-413
-
-
Bazan, J.F.1
-
6
-
-
0033571455
-
Producing selenomethionine-labeled proteins with a baculovirus expression vector system
-
Bellizzi, J.J., J. Widom, C.W. Kemp, and J. Clardy. 1999. Producing selenomethionine-labeled proteins with a baculovirus expression vector system. Structure Fold Des. 7:R263-267.
-
(1999)
Structure Fold Des.
, vol.7
-
-
Bellizzi, J.J.1
Widom, J.2
Kemp, C.W.3
Clardy, J.4
-
7
-
-
0032536814
-
Crystal structure of a cytokine-binding region of gp130
-
Bravo, J., D. Staunton, J.K. Heath, and E.Y. Jones. 1998. Crystal structure of a cytokine-binding region of gp130. EMBO J. 17:1665-1674.
-
(1998)
EMBO J.
, vol.17
, pp. 1665-1674
-
-
Bravo, J.1
Staunton, D.2
Heath, J.K.3
Jones, E.Y.4
-
8
-
-
0035896394
-
Structure of an extracellular gp130 cytokine receptor signaling complex
-
Chow, D., X. He, A.L. Snow, S. Rose-John, and K.C. Garcia. 2001. Structure of an extracellular gp130 cytokine receptor signaling complex. Science 291:2150-2155.
-
(2001)
Science
, vol.291
, pp. 2150-2155
-
-
Chow, D.1
He, X.2
Snow, A.L.3
Rose-John, S.4
Garcia, K.C.5
-
9
-
-
0032540358
-
Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
-
Clackson, T., M.H. Ultsch, J.A. Wells, and A.M. de Vos. 1998. Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J. Mol. Biol. 277:1111-1128.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 1111-1128
-
-
Clackson, T.1
Ultsch, M.H.2
Wells, J.A.3
De Vos, A.M.4
-
10
-
-
0028916599
-
A hot spot of binding energy in a hormone-receptor interface
-
Clackson, T. and J.A. Wells. 1995. A hot spot of binding energy in a hormone-receptor interface. Science 267:383-386.
-
(1995)
Science
, vol.267
, pp. 383-386
-
-
Clackson, T.1
Wells, J.A.2
-
11
-
-
0026332810
-
Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule
-
Cunningham, B.C., M. Ultsch, A.M. De Vos, M.G. Mulkerrin, K.R. Clauser, and J.A. Wells. 199 1. Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule. Science 254:821-825.
-
(1991)
Science
, vol.254
, pp. 821-825
-
-
Cunningham, B.C.1
Ultsch, M.2
De Vos, A.M.3
Mulkerrin, M.G.4
Clauser, K.R.5
Wells, J.A.6
-
12
-
-
0027132013
-
Comparison of a structural and a functional epitope
-
Cunningham, B.C. and J.A. Wells. 1993. Comparison of a structural and a functional epitope. J. Mol. Biol. 234:554-563.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 554-563
-
-
Cunningham, B.C.1
Wells, J.A.2
-
15
-
-
0034142070
-
Novel approach to phasing proteins: Derivatization by short cryo-soaking with halides
-
Dauter, Z., M. Dauter, and K.R. Rajashankar. 2000. Novel approach to phasing proteins: derivatization by short cryo-soaking with halides. Acta Crystallogr. D Biol. Crystallogr. 56(Pt 2):232-237.
-
(2000)
Acta Crystallogr. D Biol. Crystallogr.
, vol.56
, Issue.PART 2
, pp. 232-237
-
-
Dauter, Z.1
Dauter, M.2
Rajashankar, K.R.3
-
16
-
-
0026598960
-
Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
-
de Vos, A.M., M. Ultsch, and A.A. Kossiakoff. 1992. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 255:306-312.
-
(1992)
Science
, vol.255
, pp. 306-312
-
-
De Vos, A.M.1
Ultsch, M.2
Kossiakoff, A.A.3
-
17
-
-
0034662745
-
Crystal structure and functional dissection of the cytostatic cytokine oncostatin M
-
Deller, M.C., K.R. Hudson, S. Ikemizu, J. Bravo, E.Y. Jones, and J.K. Heath. 2000. Crystal structure and functional dissection of the cytostatic cytokine oncostatin M. Structure Fold Des. 8:863-874.
-
(2000)
Structure Fold Des.
, vol.8
, pp. 863-874
-
-
Deller, M.C.1
Hudson, K.R.2
Ikemizu, S.3
Bravo, J.4
Jones, E.Y.5
Heath, J.K.6
-
18
-
-
0026320870
-
Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor
-
Diederichs, K., T. Boone, and P.A. Karplus. 1991. Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor. Science 254:1779-1782.
-
(1991)
Science
, vol.254
, pp. 1779-1782
-
-
Diederichs, K.1
Boone, T.2
Karplus, P.A.3
-
19
-
-
0025730621
-
Three-dimensional structure of recombinant human interferon-gamma
-
Ealick, S.E., W.J. Cook, S. Vijay-Kumar, M. Carson, T.L. Nagabhushan, P.P. Trotta, and C.E. Bugg. 1991. Three-dimensional structure of recombinant human interferon-gamma. Science 252:698-702.
-
(1991)
Science
, vol.252
, pp. 698-702
-
-
Ealick, S.E.1
Cook, W.J.2
Vijay-Kumar, S.3
Carson, M.4
Nagabhushan, T.L.5
Trotta, P.P.6
Bugg, C.E.7
-
20
-
-
0033813066
-
Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor
-
Elkins, P.A., H.W. Christinger, Y. Sandowski, E. Sakal, A. Gertler, A.M. de Vos, and A.A. Kossiakoff. 2000. Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor. Nat. Struct. Biol. 7:808-815.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 808-815
-
-
Elkins, P.A.1
Christinger, H.W.2
Sandowski, Y.3
Sakal, E.4
Gertler, A.5
De Vos, A.M.6
Kossiakoff, A.A.7
-
21
-
-
0026764441
-
Rational design of potent antagonists to the human growth hormone receptor
-
Fuh, G., B.C. Cunningham, R. Fukunaga, S. Nagata, D.V. Goeddel, and J.A. Wells. 1992. Rational design of potent antagonists to the human growth hormone receptor. Science 256:1677-1680.
-
(1992)
Science
, vol.256
, pp. 1677-1680
-
-
Fuh, G.1
Cunningham, B.C.2
Fukunaga, R.3
Nagata, S.4
Goeddel, D.V.5
Wells, J.A.6
-
22
-
-
0035367819
-
Signaling by type I and II cytokine receptors: Ten years after
-
Gadina, M., D. Hilton, J.A. Johnston, A. Morinobu, A. Lighvani, Y.J. Zhou, R. Visconti, and J.J. O'Shea. 2001. Signaling by type I and II cytokine receptors: ten years after. Curr. Opin. Immunol. 13:363-373.
-
(2001)
Curr. Opin. Immunol.
, vol.13
, pp. 363-373
-
-
Gadina, M.1
Hilton, D.2
Johnston, J.A.3
Morinobu, A.4
Lighvani, A.5
Zhou, Y.J.6
Visconti, R.7
O'Shea, J.J.8
-
23
-
-
0033574713
-
Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface
-
Hage, T., W. Sebald, and P. Reinemer. 1999. Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface. Cell 97:271-281.
-
(1999)
Cell
, vol.97
, pp. 271-281
-
-
Hage, T.1
Sebald, W.2
Reinemer, P.3
-
24
-
-
0030783379
-
Phasing methods for protein crystallography
-
Hauptman, H. 1997. Phasing methods for protein crystallography. Curr. Opin. Struct. Biol. 7:672-680.
-
(1997)
Curr. Opin. Struct. Biol.
, vol.7
, pp. 672-680
-
-
Hauptman, H.1
-
25
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin, C.H. 1995. Dimerization of cell surface receptors in signal transduction. Cell 80:213-223.
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.H.1
-
26
-
-
0026095584
-
Determination of macromolecular structures from anomalous diffraction of synchrotron radiation
-
Hendrickson, W.A. 1991. Determination of macromolecular structures from anomalous diffraction of synchrotron radiation. Science 254:51-58.
-
(1991)
Science
, vol.254
, pp. 51-58
-
-
Hendrickson, W.A.1
-
27
-
-
0034387005
-
Synchrotron crystallography
-
Hendrickson, W.A. 2000. Synchrotron crystallography. Trends Biochem. Sci. 25:637-643.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 637-643
-
-
Hendrickson, W.A.1
-
28
-
-
0025262173
-
Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): A vehicle for direct determination of three-dimensional structure
-
Hendrickson, W.A., J.R. Horton, and D.M. LeMaster. 1990. Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure. EMBO J. 9:1665-1672.
-
(1990)
EMBO J.
, vol.9
, pp. 1665-1672
-
-
Hendrickson, W.A.1
Horton, J.R.2
LeMaster, D.M.3
-
29
-
-
0024219852
-
Crystallographic structure analysis of lamprey hemoglobin from anomalous dispersion of synchrotron radiation
-
Hendrickson, W.A., J.L. Smith, R.P. Phizackerley, and E.A. Merritt. 1988. Crystallographic structure analysis of lamprey hemoglobin from anomalous dispersion of synchrotron radiation. Proteins 4:77-88.
-
(1988)
Proteins
, vol.4
, pp. 77-88
-
-
Hendrickson, W.A.1
Smith, J.L.2
Phizackerley, R.P.3
Merritt, E.A.4
-
30
-
-
0034456782
-
Growth hormone receptor antagonist therapy in acromegalic patients resistant to somatostatin analogs
-
Herman-Bonert, V.S., K. Zib, J.A. Scarlett, and S. Melmed. 2000. Growth hormone receptor antagonist therapy in acromegalic patients resistant to somatostatin analogs. J. Clin. Endocrinol. Metab. 85:295-2961.
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 295-2961
-
-
Herman-Bonert, V.S.1
Zib, K.2
Scarlett, J.A.3
Melmed, S.4
-
31
-
-
84944510121
-
Cryocrystallography of biological macromolecules: A generally applicable method
-
Hope, H. 1988. Cryocrystallography of biological macromolecules: a generally applicable method. Acta Crystallogr. B 44(Pt 1):22-26.
-
(1988)
Acta Crystallogr. B
, vol.44
, Issue.PART 1
, pp. 22-26
-
-
Hope, H.1
-
32
-
-
0026206788
-
Sparse Matrix Sampling: A screening method for crystallization of proteins
-
Jancarik, J.J. and S.H. Kim. 1991. Sparse Matrix Sampling: a screening method for crystallization of proteins. J. Appl. Crystallogr. 24-409.
-
(1991)
J. Appl. Crystallogr.
, pp. 24-409
-
-
Jancarik, J.J.1
Kim, S.H.2
-
33
-
-
0032539954
-
Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1
-
Johnson, D.L., F.X. Farrell, F.P. Barbone, F.J. McMahon, J. Tullai, K. Hoey, O. Livnah, N.C. Wrighton, et al. 1998. Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1. Biochemistry 37:3699-3710.
-
(1998)
Biochemistry
, vol.37
, pp. 3699-3710
-
-
Johnson, D.L.1
Farrell, F.X.2
Barbone, F.P.3
McMahon, F.J.4
Tullai, J.5
Hoey, K.6
Livnah, O.7
Wrighton, N.C.8
-
34
-
-
0037047128
-
Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1
-
Jones, B.C., N.J. Logsdon, K. Josephson, J. Cook, P.A. Barry, and M.R. Walter. 2002. Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc. Natl. Acad. Sci. USA 99:9404-9409.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9404-9409
-
-
Jones, B.C.1
Logsdon, N.J.2
Josephson, K.3
Cook, J.4
Barry, P.A.5
Walter, M.R.6
-
35
-
-
0034607685
-
Design and analysis of an engineered human interleukin-10 monomer
-
Josephson, K., R. DiGiacomo, S.R. Indelicato, A.H. Iyo, T.L. Nagabhushan, M.H. Parker, M.R. Walter, and A.H. Ayo. 2000. Design and analysis of an engineered human interleukin-10 monomer. J. Biol. Chem. 275:13552-13557.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13552-13557
-
-
Josephson, K.1
DiGiacomo, R.2
Indelicato, S.R.3
Iyo, A.H.4
Nagabhushan, T.L.5
Parker, M.H.6
Walter, M.R.7
Ayo, A.H.8
-
36
-
-
0036065431
-
Non-competitive antibody neutralization of IL-10 revealed by protein engineering and X-ray crystallography
-
Josephson, K., B.C. Jones, L.J. Walter, R. DiGiacomo, S.R. Indelicato, and M.R. Walter. 2002. Non-competitive antibody neutralization of IL-10 revealed by protein engineering and X-ray crystallography. Structure 10:981-987.
-
(2002)
Structure
, vol.10
, pp. 981-987
-
-
Josephson, K.1
Jones, B.C.2
Walter, L.J.3
DiGiacomo, R.4
Indelicato, S.R.5
Walter, M.R.6
-
37
-
-
0034897552
-
Crystal structure of the IL-10/IL-10R1 complex reveals shared receptor binding site
-
Josephson, K., N.J. Logsdon, and M.R. Walter. 2001. Crystal structure of the IL-10/IL-10R1 complex reveals shared receptor binding site. Immunity 15:35-46.
-
(2001)
Immunity
, vol.15
, pp. 35-46
-
-
Josephson, K.1
Logsdon, N.J.2
Walter, M.R.3
-
38
-
-
0035214095
-
Purification, crystallization and preliminary X-ray diffraction of a complex between IL-10 and soluble IL-10R1
-
Josephson, K., D.T. McPherson, and M.R. Walter. 2001. Purification, crystallization and preliminary X-ray diffraction of a complex between IL-10 and soluble IL-10R1. Acta Crystallogr. D Biol. Crystallogr. 57:1908-1911.
-
(2001)
Acta Crystallogr. D Biol. Crystallogr.
, vol.57
, pp. 1908-1911
-
-
Josephson, K.1
McPherson, D.T.2
Walter, M.R.3
-
39
-
-
0030704730
-
The crystal structure of human interferon beta at 2.2-A resolution
-
Karpusas, M., M. Nolte, C.B. Benton, W. Meier, W.N. Lipscomb, and S. Goelz. 1997. The crystal structure of human interferon beta at 2.2-A resolution. Proc. Natl. Acad. Sci. USA 94:11813-11818.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11813-11818
-
-
Karpusas, M.1
Nolte, M.2
Benton, C.B.3
Meier, W.4
Lipscomb, W.N.5
Goelz, S.6
-
40
-
-
0037138370
-
Signaling through the JAK/STAT pathway, recent advances and future challenges
-
Kisseleva, T., S. Bhattacharya, J. Braunstein, and C.W. Schindler. 2002. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285:1-24.
-
(2002)
Gene
, vol.285
, pp. 1-24
-
-
Kisseleva, T.1
Bhattacharya, S.2
Braunstein, J.3
Schindler, C.W.4
-
41
-
-
0033548254
-
Probability analysis of variational crystallization and its application to gp 120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1)
-
Kwong, P.D., R. Wyatt, E. Desjardins, J. Robinson, J.S. Culp, B.D. Hellmig, R.W. Sweet, J. Sodroski, et al. 1999. Probability analysis of variational crystallization and its application to gp 120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1). J. Biol. Chem. 274:4115-4123.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 4115-4123
-
-
Kwong, P.D.1
Wyatt, R.2
Desjardins, E.3
Robinson, J.4
Culp, J.S.5
Hellmig, B.D.6
Sweet, R.W.7
Sodroski, J.8
-
42
-
-
0033762983
-
Current state of automated crystallographic data analysis
-
Lamzin, V.S. and A. Perrakis. 2000. Current state of automated crystallographic data analysis. Nat. Struct. Biol. 7 (Suppl):978-981.
-
(2000)
Nat. Struct. Biol.
, vol.7
, Issue.SUPPL.
, pp. 978-981
-
-
Lamzin, V.S.1
Perrakis, A.2
-
43
-
-
0029798402
-
Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 A
-
Livnah, O., E.A. Stura, D.L. Johnson, S.A. Middleton, L.S. Mulcahy, N.C. Wrighton, W.J. Dower, L.K. Jolliffe, et al. 1996. Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A. Science 273:464-471.
-
(1996)
Science
, vol.273
, pp. 464-471
-
-
Livnah, O.1
Stura, E.A.2
Johnson, D.L.3
Middleton, S.A.4
Mulcahy, L.S.5
Wrighton, N.C.6
Dower, W.J.7
Jolliffe, L.K.8
-
44
-
-
0033548259
-
Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation
-
Livnah, O., E.A. Stura, S.A. Middleton, D.L. Johnson, L.K. Jolliffe, and I.A. Wilson. 1999. Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science 283:987-990.
-
(1999)
Science
, vol.283
, pp. 987-990
-
-
Livnah, O.1
Stura, E.A.2
Middleton, S.A.3
Johnson, D.L.4
Jolliffe, L.K.5
Wilson, I.A.6
-
45
-
-
0027136111
-
Affinity maturation of human growth hormone by monovalent phage display
-
Lowman, H.B. and J.A. Wells. 1993. Affinity maturation of human growth hormone by monovalent phage display. J. Mol. Biol. 234:564-578.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 564-578
-
-
Lowman, H.B.1
Wells, J.A.2
-
46
-
-
0027155448
-
A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5
-
Milburn, M.V., A.M. Hassell, M.H. Lambert, S.R. Jordan, A.E. Proudfoot, P. Graber, and T.N. Wells. 1993. A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5. Nature 363:172-176.
-
(1993)
Nature
, vol.363
, pp. 172-176
-
-
Milburn, M.V.1
Hassell, A.M.2
Lambert, M.H.3
Jordan, S.R.4
Proudfoot, A.E.5
Graber, P.6
Wells, T.N.7
-
47
-
-
0035936618
-
Development of a technology for automation and miniaturization of protein crystallization
-
Mueller, U., L. Nyarsik, M. Horn, H. Rauth, T. Przewieslik, W. Saenger, H. Lehrach, and H. Eickhoff. 2001. Development of a technology for automation and miniaturization of protein crystallization. J. Biotechnol. 85:7-14.
-
(2001)
J. Biotechnol.
, vol.85
, pp. 7-14
-
-
Mueller, U.1
Nyarsik, L.2
Horn, M.3
Rauth, H.4
Przewieslik, T.5
Saenger, W.6
Lehrach, H.7
Eickhoff, H.8
-
48
-
-
0034940904
-
Protein crystal structure solution by fast incorporation of negatively and positively charged anomalous scatterers
-
Nagem, R.A., Z. Dauter, and I. Polikarpov. 2001. Protein crystal structure solution by fast incorporation of negatively and positively charged anomalous scatterers. Acta Crystallogr. D Biol. Crystallogr. 57:996-1002.
-
(2001)
Acta Crystallogr. D Biol. Crystallogr.
, vol.57
, pp. 996-1002
-
-
Nagem, R.A.1
Dauter, Z.2
Polikarpov, I.3
-
49
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
O'Shea, J.J., M. Gadina, and R.D. Schreiber. 2002. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109 (Suppl):S121-131.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
50
-
-
0026727235
-
Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor
-
Pandit, J., A. Bohm, J. Jancarik, R. Halenbeck, K. Koths, and S.H. Kim. 1992. Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor. Science 258:1358-1362.
-
(1992)
Science
, vol.258
, pp. 1358-1362
-
-
Pandit, J.1
Bohm, A.2
Jancarik, J.3
Halenbeck, R.4
Koths, K.5
Kim, S.H.6
-
51
-
-
0030589627
-
Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography
-
Radhakrishnan, R., L.J. Walter, A. Hruza, P. Reichert, P.P. Trotta, T.L. Nagabhushan, and M.R. Walter. 1996. Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography. Structure 4:1453-1463.
-
(1996)
Structure
, vol.4
, pp. 1453-1463
-
-
Radhakrishnan, R.1
Walter, L.J.2
Hruza, A.3
Reichert, P.4
Trotta, P.P.5
Nagabhushan, T.L.6
Walter, M.R.7
-
52
-
-
0033548060
-
Crystal structure of ovine interferon-tau at 2.1 A resolution
-
Radhakrishnan, R., L.J. Walter, P.S. Subramaniam, H.M. Johnson, and M.R. Walter. 1999. Crystal structure of ovine interferon-tau at 2.1 A resolution. J. Mol. Biol. 286:151-162.
-
(1999)
J. Mol. Biol.
, vol.286
, pp. 151-162
-
-
Radhakrishnan, R.1
Walter, L.J.2
Subramaniam, P.S.3
Johnson, H.M.4
Walter, M.R.5
-
53
-
-
0035091323
-
The structure and activity of a monomeric interferon-gamma:alpha-chain receptor signaling complex
-
Randal, M. and A.A. Kossiakoff. 2001. The structure and activity of a monomeric interferon-gamma:alpha-chain receptor signaling complex. Structure (Camb.) 9:155-163.
-
(2001)
Structure (Camb.)
, vol.9
, pp. 155-163
-
-
Randal, M.1
Kossiakoff, A.A.2
-
54
-
-
0033548048
-
Erythropoietin receptor activation by a ligand-induced conformation change
-
Remy, I., I.A. Wilson and S.W. Michnick. 1999. Erythropoietin receptor activation by a ligand-induced conformation change. Science 283:990-993.
-
(1999)
Science
, vol.283
, pp. 990-993
-
-
Remy, I.1
Wilson, I.A.2
Michnick, S.W.3
-
55
-
-
14344267196
-
High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5′AMP
-
Retailleau, P., Y. Yin, M. Hu, J. Roach, G. Bricogne, C. Vonrhein, P. Roversi, E. Blanc, et al. 2001. High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5′AMP. Acta Crystallogr. D Biol. Crystallogr. 57:1595-1608.
-
(2001)
Acta Crystallogr. D Biol. Crystallogr.
, vol.57
, pp. 1595-1608
-
-
Retailleau, P.1
Yin, Y.2
Hu, M.3
Roach, J.4
Bricogne, G.5
Vonrhein, C.6
Roversi, P.7
Blanc, E.8
-
56
-
-
0029144646
-
The crystal structure of murine leukemia inhibitory factor
-
discussion 187-178
-
Robinson, R.C., L.M. Grey, D. Staunton, D.I. Stuart, J.K. Heath, and E.Y. Jones. 1995. The crystal structure of murine leukemia inhibitory factor. Ann. NY Acad. Sci. 762:179-187; discussion 187-178.
-
(1995)
Ann. NY Acad. Sci.
, vol.762
, pp. 179-187
-
-
Robinson, R.C.1
Grey, L.M.2
Staunton, D.3
Stuart, D.I.4
Heath, J.K.5
Jones, E.Y.6
-
57
-
-
0028774714
-
Corocrystallography
-
Rodgers, D.W. 1994. Corocrystallography. Structure 2:1135-1140.
-
(1994)
Structure
, vol.2
, pp. 1135-1140
-
-
Rodgers, D.W.1
-
58
-
-
0028425473
-
Comparison of four independently determined structures of human recombinant interleukin-4
-
Smith, L.J., C. Redfield, R.A. Smith, C.M. Dobson, G.M. Clore, A.M. Gronenborn, M.R. Walter, T.L. Naganbushan, et al. 1994. Comparison of four independently determined structures of human recombinant interleukin-4. Nat. Struct. Biol. 1:301-310.
-
(1994)
Nat. Struct. Biol.
, vol.1
, pp. 301-310
-
-
Smith, L.J.1
Redfield, C.2
Smith, R.A.3
Dobson, C.M.4
Clore, G.M.5
Gronenborn, A.M.6
Walter, M.R.7
Naganbushan, T.L.8
-
59
-
-
0031041014
-
1.9 A crystal structure of intetleukin 6: Implications for a novel mode of receptor dimerization and signaling
-
Somers, W., M. Stahl, and J.S. Seehra. 1997. 1.9 A crystal structure of intetleukin 6: implications for a novel mode of receptor dimerization and signaling. EMBO J 16:989-997.
-
(1997)
EMBO J.
, vol.16
, pp. 989-997
-
-
Somers, W.1
Stahl, M.2
Seehra, J.S.3
-
60
-
-
0028032203
-
The X-ray structure of a growth hormone-prolactin receptor complex
-
Somers, W., M. Ultsch, A.M. De Vos, and A.A. Kossiakoff. 1994. The X-ray structure of a growth hormone-prolactin receptor complex. Nature 372:478-481.
-
(1994)
Nature
, vol.372
, pp. 478-481
-
-
Somers, W.1
Ultsch, M.2
De Vos, A.M.3
Kossiakoff, A.A.4
-
61
-
-
0027145507
-
Cytokine structural taxonomy and mechanisms of receptor engagement
-
Sprang, S.R. and J.F. Bazan. 1993. Cytokine structural taxonomy and mechanisms of receptor engagement. Curr. Opin. Struct. Biol. 3:815-821.
-
(1993)
Curr. Opin. Struct. Biol.
, vol.3
, pp. 815-821
-
-
Sprang, S.R.1
Bazan, J.F.2
-
62
-
-
0033794367
-
High-throughput protein crystallization
-
Stevens, R.C. 2000. High-throughput protein crystallization. Curr. Opin. Struct. Biol. 10:558-563.
-
(2000)
Curr. Opin. Struct. Biol.
, vol.10
, pp. 558-563
-
-
Stevens, R.C.1
-
63
-
-
0032188942
-
Efficiency of signalling through cytokine receptors depends critically on receptor orientation
-
Syed, R.S., S.W. Reid, C. Li, J.C. Cheetham, K.H. Aoki, B. Liu, H. Zhan, T.D. Osslund, et al. 1998. Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature 395:511-516.
-
(1998)
Nature
, vol.395
, pp. 511-516
-
-
Syed, R.S.1
Reid, S.W.2
Li, C.3
Cheetham, J.C.4
Aoki, K.H.5
Liu, B.6
Zhan, H.7
Osslund, T.D.8
-
64
-
-
0029015733
-
Characterization of recombinant extracellular domain of human interleukin-10 receptor
-
Tan, J.C., S. Braun, H. Rong, R. DiGiacomo, E. Dolphin, S. Baldwin, S.K. Narula, P.J. Zavodny, et al. 1995. Characterization of recombinant extracellular domain of human interleukin-10 receptor. J. Biol. Chem. 270:12906-12911.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12906-12911
-
-
Tan, J.C.1
Braun, S.2
Rong, H.3
DiGiacomo, R.4
Dolphin, E.5
Baldwin, S.6
Narula, S.K.7
Zavodny, P.J.8
-
66
-
-
0034665458
-
Observation of all unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex
-
Thiel, D.J., M.H. le Du, R.L. Walter, A. D'Arcy, C. Chene, M. Fountoulakis, G. Garotta, F.K. Winkler, et al. 2000. Observation of all unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex. Structure Fold Des. 8:927-936.
-
(2000)
Structure Fold Des.
, vol.8
, pp. 927-936
-
-
Thiel, D.J.1
Le Du, M.H.2
Walter, R.L.3
D'Arcy, A.4
Chene, C.5
Fountoulakis, M.6
Garotta, G.7
Winkler, F.K.8
-
67
-
-
0034690311
-
Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant
-
Trainer, P.J., W.M. Drake, L. Katznelson, P.U. Freda, V. Herman-Bonert, A.J. van der Lely, E.V. Dimaraki, P.M. Stewart, et al. 2000. Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N. Engl. J. Med. 342:1171-1177.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1171-1177
-
-
Trainer, P.J.1
Drake, W.M.2
Katznelson, L.3
Freda, P.U.4
Herman-Bonert, V.5
Van der Lely, A.J.6
Dimaraki, E.V.7
Stewart, P.M.8
-
68
-
-
0035944825
-
Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist
-
van der Lely, A.J., R.K. Hutson, P.J. Trainer, G.M. Besser, A.L. Barkan, L. Katznelson, A. Klibanski, V. Herman-Bonert, et al. 2001. Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet 358:1754-1759.
-
(2001)
Lancet
, vol.358
, pp. 1754-1759
-
-
Van der Lely, A.J.1
Hutson, R.K.2
Trainer, P.J.3
Besser, G.M.4
Barkan, A.L.5
Katznelson, L.6
Klibanski, A.7
Herman-Bonert, V.8
-
69
-
-
0026520373
-
Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor
-
Walter, M.R., W.J. Cook, S.E. Ealick, T.L. Nagabhushan, P.P. Trotta, and C.E. Bugg. 1992. Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor. J. Mol. Biol. 224:1075-1085.
-
(1992)
J. Mol. Biol.
, vol.224
, pp. 1075-1085
-
-
Walter, M.R.1
Cook, W.J.2
Ealick, S.E.3
Nagabhushan, T.L.4
Trotta, P.P.5
Bugg, C.E.6
-
70
-
-
0026699913
-
Crystal structure of recombinant human interleukin-4
-
Walter, M.R., W.J. Cook, B.G. Zhao, R.P. Cameron, Jr., S.E. Ealick, R.L. Walter, Jr., P. Reichert, T.L. Nagabhushan, et al. 1992. Crystal structure of recombinant human interleukin-4. J. Biol. Chem. 267:20371-20376.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 20371-20376
-
-
Walter, M.R.1
Cook, W.J.2
Zhao, B.G.3
Cameron R.P., Jr.4
Ealick, S.E.5
Walter R.L., Jr.6
Reichert, P.7
Nagabhushan, T.L.8
-
71
-
-
0029148581
-
Crystal structure of interleukin 10 reveals an interferon gamma-like fold
-
Walter, M.R. and T.L. Nagabhushan. 1995. Crystal structure of interleukin 10 reveals an interferon gamma-like fold. Biochemistry 34:12118-12125.
-
(1995)
Biochemistry
, vol.34
, pp. 12118-12125
-
-
Walter, M.R.1
Nagabhushan, T.L.2
-
72
-
-
0029067876
-
Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor
-
Walter, M.R., W.T. Windsor, T.L. Nagabhushan, D.J. Lundell, C.A. Lunn, P.J. Zauodny, and S.K. Narula. 1995. Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor, Nature 376:230-235.
-
(1995)
Nature
, vol.376
, pp. 230-235
-
-
Walter, M.R.1
Windsor, W.T.2
Nagabhushan, T.L.3
Lundell, D.J.4
Lunn, C.A.5
Zauodny, P.J.6
Narula, S.K.7
-
73
-
-
0029645281
-
High-resolution macromolecular structure determination using CCD detectors and synchrotron radiation
-
Walter, R.L., D.J. Thiel, S.L. Barna, M.W. Tate, M.E. Wall, E.E Eikenberry, S.M. Gruner, and S.E. Ealick. 1995. High-resolution macromolecular structure determination using CCD detectors and synchrotron radiation. Structure 3:835-844.
-
(1995)
Structure
, vol.3
, pp. 835-844
-
-
Walter, R.L.1
Thiel, D.J.2
Barna, S.L.3
Tate, M.W.4
Wall, M.E.5
Eikenberry, E.E.6
Gruner, S.M.7
Ealick, S.E.8
-
75
-
-
0027346824
-
The molecular basis for growth hormone-receptor interactions
-
Wells, J.A., B.C. Cunningham, G. Fuh, H.B. Lowman, S.H. Bass, M.G. Mulkerrin, M. Ultsch, and A.M. deVos. 1993. The molecular basis for growth hormone-receptor interactions. Recent Prog. Horm. Res. 48:253-275.
-
(1993)
Recent Prog. Horm. Res.
, vol.48
, pp. 253-275
-
-
Wells, J.A.1
Cunningham, B.C.2
Fuh, G.3
Lowman, H.B.4
Bass, S.H.5
Mulkerrin, M.G.6
Ultsch, M.7
DeVos, A.M.8
-
76
-
-
0033301681
-
New strategies for protein crystal growth
-
Wiencek, J.M. 1999. New strategies for protein crystal growth. Annu. Rev. Biomed. Eng. 1:505-534.
-
(1999)
Annu. Rev. Biomed. Eng.
, vol.1
, pp. 505-534
-
-
Wiencek, J.M.1
-
77
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton, N.C., F.X. Farrell, R. Chang, A.K. Kashyap, F.P. Barbone, L.S. Mulcahy, D.L. Johnson, R.W. Barrett, et al. 1996. Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273:458-464.
-
(1996)
Science
, vol.273
, pp. 458-464
-
-
Wrighton, N.C.1
Farrell, F.X.2
Chang, R.3
Kashyap, A.K.4
Barbone, F.P.5
Mulcahy, L.S.6
Johnson, D.L.7
Barrett, R.W.8
-
78
-
-
0034679726
-
Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12
-
Yoon, C., S.C. Johnston, J. Tang, M. Stahl, J.F. Tobin, and W.S. Somers. 2000. Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12. EMBO J. 19:3530-3541.
-
(2000)
EMBO J.
, vol.19
, pp. 3530-3541
-
-
Yoon, C.1
Johnston, S.C.2
Tang, J.3
Stahl, M.4
Tobin, J.F.5
Somers, W.S.6
-
79
-
-
0029644946
-
Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma
-
Zdanov, A., C. Schalk-Hihi, A. Gustchina, M. Tsang, J. Weatherbee, and A. Wlodawer. 1995. Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma. Structure 3:591-601.
-
(1995)
Structure
, vol.3
, pp. 591-601
-
-
Zdanov, A.1
Schalk-Hihi, C.2
Gustchina, A.3
Tsang, M.4
Weatherbee, J.5
Wlodawer, A.6
-
80
-
-
0030977992
-
Crystal structure of the obese protein leptin-E100
-
Zhang, F., M.B. Basinski, J.M. Beals, S.L. Briggs, L.M. Churgay, D.K. Clawson, R.D. DiMarchi, T.C. Furman, et al. 1997. Crystal structure of the obese protein leptin-E100. Nature 387:206-209.
-
(1997)
Nature
, vol.387
, pp. 206-209
-
-
Zhang, F.1
Basinski, M.B.2
Beals, J.M.3
Briggs, S.L.4
Churgay, L.M.5
Clawson, D.K.6
DiMarchi, R.D.7
Furman, T.C.8
|