메뉴 건너뛰기




Volumn 6, Issue 1, 1996, Pages 3-10

Neurogenic genes and vertebrate neurogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIFFERENTIATION; FLY; GENE ACTIVITY; NERVOUS SYSTEM DEVELOPMENT; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; VERTEBRATE; WORM;

EID: 0029930494     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(96)80002-X     Document Type: Article
Times cited : (235)

References (75)
  • 1
    • 0025346055 scopus 로고
    • Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila
    • Simpson P: Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila. Development 1990, 109:509-519.
    • (1990) Development , vol.109 , pp. 509-519
    • Simpson, P.1
  • 2
    • 0027191864 scopus 로고
    • Cell interactions and gene interactions in peripheral neurogenesis
    • Ghysen A, Dambly-Chaudière C, Jan LY, Jan YN: Cell interactions and gene interactions in peripheral neurogenesis. Genes Dev 1993, 7:723-733.
    • (1993) Genes Dev , vol.7 , pp. 723-733
    • Ghysen, A.1    Dambly-Chaudière, C.2    Jan, L.Y.3    Jan, Y.N.4
  • 3
    • 0027139591 scopus 로고
    • Falling off the knife edge
    • Sternberg PW: Falling off the knife edge. Curr Biol 1993, 3:763-765.
    • (1993) Curr Biol , vol.3 , pp. 763-765
    • Sternberg, P.W.1
  • 4
    • 0028670620 scopus 로고
    • Delta-Notch signaling and Drosophila cell fate choice
    • Muskavitch MAT: Delta-Notch signaling and Drosophila cell fate choice. Dev Biol 1994, 166:415-430. A clear and comprehensive review.
    • (1994) Dev Biol , vol.166 , pp. 415-430
    • Muskavitch, M.A.T.1
  • 6
    • 0026532554 scopus 로고
    • Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo
    • Skeath JB, Carroll SB: Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo. Development 1992, 114:939-946.
    • (1992) Development , vol.114 , pp. 939-946
    • Skeath, J.B.1    Carroll, S.B.2
  • 7
    • 0025761636 scopus 로고
    • Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc
    • Cubas P, De Celis J-F, Campuzano S, Modolell J: Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc. Genes Dev 1991, 5:996-1008.
    • (1991) Genes Dev , vol.5 , pp. 996-1008
    • Cubas, P.1    De Celis, J.-F.2    Campuzano, S.3    Modolell, J.4
  • 8
    • 0027416250 scopus 로고
    • Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development
    • Kooh PJ, Fehon RG, Muskavitch MAT: Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 1993, 117:493-507.
    • (1993) Development , vol.117 , pp. 493-507
    • Kooh, P.J.1    Fehon, R.G.2    Muskavitch, M.A.T.3
  • 9
    • 0000010724 scopus 로고
    • Early neurogenesis in Drosophila melanogaster
    • Edited by Bate M, Martinez-Arías A. Cold Spring Harbor: Cold Spring Harbor Laboratory
    • Campos-Ortega JA: Early neurogenesis in Drosophila melanogaster. In The Development of Drosophila melanogaster. Edited by Bate M, Martinez-Arías A. Cold Spring Harbor: Cold Spring Harbor Laboratory; 1993:1091-1129.
    • (1993) The Development of Drosophila Melanogaster , pp. 1091-1129
    • Campos-Ortega, J.A.1
  • 10
    • 0025115887 scopus 로고
    • A dual function of the Notch gene in Drosophila sensillum development
    • Hartenstein V, Posakony JW: A dual function of the Notch gene in Drosophila sensillum development. Dev Biol 1990, 142:13-30.
    • (1990) Dev Biol , vol.142 , pp. 13-30
    • Hartenstein, V.1    Posakony, J.W.2
  • 11
    • 0028936424 scopus 로고
    • Neurogenic and proneural genes control cell fate specification in the Drosophila endoderm
    • Tepass U, Hartenstein V: Neurogenic and proneural genes control cell fate specification in the Drosophila endoderm. Development 1995, 121:393-405. Shows that the whole system of neurogenic and proneural genes operates in almost the same way in the gut as in the nervous system to single out a subset of cells for a special fate.
    • (1995) Development , vol.121 , pp. 393-405
    • Tepass, U.1    Hartenstein, V.2
  • 12
    • 0028820168 scopus 로고
    • Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis
    • Carmena A, Bate M, Jiménez F: lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis. Genes Dev 1995, 9:2373-2383.
    • (1995) Genes Dev , vol.9 , pp. 2373-2383
    • Carmena, A.1    Bate, M.2    Jiménez, F.3
  • 13
    • 0028053438 scopus 로고
    • Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila
    • Hoch M, Broadie K, Jackle H, Skaer H: Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila. Development 1994, 120:3439-3450.
    • (1994) Development , vol.120 , pp. 3439-3450
    • Hoch, M.1    Broadie, K.2    Jackle, H.3    Skaer, H.4
  • 14
    • 0026346849 scopus 로고
    • The determination of sense organs in Drosophila: Effect of neurogenic mutations in the embryo
    • Goriely A, Dumont N, Dambly-Chaudière C, Ghysen A: The determination of sense organs in Drosophila: effect of neurogenic mutations in the embryo. Development 1991, 113:1395-1404.
    • (1991) Development , vol.113 , pp. 1395-1404
    • Goriely, A.1    Dumont, N.2    Dambly-Chaudière, C.3    Ghysen, A.4
  • 15
    • 0025971830 scopus 로고
    • The choice of cell fate in the epidermis of Drosophila
    • Heitzler P, Simpson P: The choice of cell fate in the epidermis of Drosophila. Cell 1991, 64:1083-1092.
    • (1991) Cell , vol.64 , pp. 1083-1092
    • Heitzler, P.1    Simpson, P.2
  • 16
    • 0028641294 scopus 로고
    • Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision
    • Wilkinson HA, Fitzgerald K, Greenwald I: Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision. Cell 1994, 79:1187-1198. A thoroughly analyzed example of lateral inhibition with feedback, which serves to single out one cell of an initially equivalent pair to become the anchor cell of the nematode gonad. In this system, activation of the Notch homologue lin-12 causes downregulation of expression of the Delta homologue lag-2, as well as stimulating expression of lin-12 itself.
    • (1994) Cell , vol.79 , pp. 1187-1198
    • Wilkinson, H.A.1    Fitzgerald, K.2    Greenwald, I.3
  • 17
    • 0028148335 scopus 로고
    • Lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans
    • Henderson ST, Gao D, Lambie EJ, Kimble J: lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans. Development 1994, 120:2913-2924.
    • (1994) Development , vol.120 , pp. 2913-2924
    • Henderson, S.T.1    Gao, D.2    Lambie, E.J.3    Kimble, J.4
  • 18
    • 0028072860 scopus 로고
    • The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo
    • Jennings B, Preiss A, Delidakis C, Bray S: The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo. Development 1994, 120:3537-3548.
    • (1994) Development , vol.120 , pp. 3537-3548
    • Jennings, B.1    Preiss, A.2    Delidakis, C.3    Bray, S.4
  • 19
    • 0028786177 scopus 로고
    • Role of Notch and achaete/scute complex in the expression of Enhancer of split bHLH proteins
    • Jennings B, De Celis J, Delidakis C, Bray S: Role of Notch and achaete/scute complex in the expression of Enhancer of split bHLH proteins. Development 1995, 121:3745-3752. Expression of E(spl)-C genes, assayed with antibodies against the protein products, is shown to correlate with the level of Notch activation in the same cell, both in the embryonic CNS and in imaginal discs. Ectopic expression of an activated Notch construct causes ectopic accumulation of E(spl)-C proteins, even in the absence of AS-C proteins. Thus, E(spl)-C genes are directly regulated by Notch, rather than by the products of the proneural genes.
    • (1995) Development , vol.121 , pp. 3745-3752
    • Jennings, B.1    De Celis, J.2    Delidakis, C.3    Bray, S.4
  • 20
    • 0026738021 scopus 로고
    • The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells
    • Schrons H, Knust E, Campos-Ortega JA: The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells. Genetics 1992, 132:481-503.
    • (1992) Genetics , vol.132 , pp. 481-503
    • Schrons, H.1    Knust, E.2    Campos-Ortega, J.A.3
  • 21
    • 0028170530 scopus 로고
    • Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
    • Paroush Z, Finley RL, Kidd T, Wainwright M, Ingham PW, Brent R, Ish-Horowicz D: Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell 1994, 79:805-815. Clarifies the role of groucho as a neurogenic gene and its relationship to the function of E(spl)-C. Groucho protein binds directly to a subset of bHLH proteins, including those encoded by E(spl)-C. These Groucho partners all function as repressors of transcription and require Groucho as co-repressor.
    • (1994) Cell , vol.79 , pp. 805-815
    • Paroush, Z.1    Finley, R.L.2    Kidd, T.3    Wainwright, M.4    Ingham, P.W.5    Brent, R.6    Ish-Horowicz, D.7
  • 22
    • 0030044345 scopus 로고    scopus 로고
    • Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila
    • Heitzler P, Bourouis M, Ruel L, Carteret C, Simpson P: Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 1996, 122:161-171. By analysis of genetic mosaics in the Drosophila PNS containing clones of cells that lack E(spl)-C genes or groucho, it is shown that the products of these genes are required for reception of inhibition but not for delivery of inhibition (i.e. production of Delta), and that they act downstream of Notch and upstream of the AS-C genes whose transcription they directly inhibit. Clones lacking AS-C genes as well as E(spl)-C genes fail to make sensory bristles and do not deliver inhibition to their neighbours (i.e. do not produce Delta). Thus, AS-C genes are apparently required for production of Delta, and Notch activation inhibits Delta production via E(spl)-C-dependent inhibition of the AS-C genes.
    • (1996) Development , vol.122 , pp. 161-171
    • Heitzler, P.1    Bourouis, M.2    Ruel, L.3    Carteret, C.4    Simpson, P.5
  • 23
    • 0028061455 scopus 로고
    • Lateral inhibition mediated by the Drosophila neurogenic gene Delta is enhanced by proneural proteins
    • Kunisch M, Haenlin M, Campos-Ortega JA: Lateral inhibition mediated by the Drosophila neurogenic gene Delta is enhanced by proneural proteins. Proc Natl Acad Sci USA 1994, 91:10139-10143.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10139-10143
    • Kunisch, M.1    Haenlin, M.2    Campos-Ortega, J.A.3
  • 24
    • 0028879651 scopus 로고
    • A collection of cortical crescents: Asymmetric protein localization in CNS precursor cells
    • Doe CQ, Spana EP: A collection of cortical crescents: asymmetric protein localization in CNS precursor cells. Neuron 1995, 15:991-995. Excellent brief summary of the recent evidence that asymmetric localization of Numb and Prospero at one pole of a dividing neuroblast or sensory mother cell controls the difference of fate between the two daughter cells.
    • (1995) Neuron , vol.15 , pp. 991-995
    • Doe, C.Q.1    Spana, E.P.2
  • 25
    • 0028818805 scopus 로고
    • Asymmetric segregation of Numb and Prospero during cell division
    • Knoblich JA, Jan LY, Jan YN: Asymmetric segregation of Numb and Prospero during cell division. Nature 1995, 377:624-627.
    • (1995) Nature , vol.377 , pp. 624-627
    • Knoblich, J.A.1    Jan, L.Y.2    Jan, Y.N.3
  • 26
    • 0027947609 scopus 로고
    • Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
    • Rhyu MS, Jan LY, Jan YN: Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 1994, 76:477-491.
    • (1994) Cell , vol.76 , pp. 477-491
    • Rhyu, M.S.1    Jan, L.Y.2    Jan, Y.N.3
  • 27
    • 0028785304 scopus 로고
    • Asymmetric segregation of the homeodomain protein Prospero during Drosophila development
    • Hirata J, Nakagoshi H, Nabeshima Y, Matsuzaki F: Asymmetric segregation of the homeodomain protein Prospero during Drosophila development Nature 1995, 377:627-630.
    • (1995) Nature , vol.377 , pp. 627-630
    • Hirata, J.1    Nakagoshi, H.2    Nabeshima, Y.3    Matsuzaki, F.4
  • 28
    • 0028802562 scopus 로고
    • Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS
    • Spana EP, Kopczynski C, Goodman CS, Doe CQ: Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 1995, 121:3489-3494.
    • (1995) Development , vol.121 , pp. 3489-3494
    • Spana, E.P.1    Kopczynski, C.2    Goodman, C.S.3    Doe, C.Q.4
  • 29
    • 0028803382 scopus 로고
    • The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila
    • Spana EP, Doe CQ: The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila. Development 1995, 121:3187-3195.
    • (1995) Development , vol.121 , pp. 3187-3195
    • Spana, E.P.1    Doe, C.Q.2
  • 30
    • 0029085935 scopus 로고
    • Signalling downstream of activated mammalian Notch
    • Jarriault S, Brou C, Logeat F, Schroeter EH, Kopan R, Israel A: Signalling downstream of activated mammalian Notch. Nature 1995, 377:355-358. Experiments with transfected mammalian cells in culture show that an intracellular Notch fragment binds to the Su(H) homologue RBP-Jκ, and that the two proteins together form a complex in the nucleus that binds to promoter regions of the E(spl) homologue HES-1, and presumably activates transcription.
    • (1995) Nature , vol.377 , pp. 355-358
    • Jarriault, S.1    Brou, C.2    Logeat, F.3    Schroeter, E.H.4    Kopan, R.5    Israel, A.6
  • 31
    • 0030003538 scopus 로고    scopus 로고
    • Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation by the extracellular domain
    • in press
    • Kopan R, Schroeter EH, Nye JS, Weintraub H: Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc Natl Acad Sci USA 1996, in press. Cultured mammalian cells transfected with various mouse Notch constructs are used to show that Notch activation depends on cleavage at a site just internal to the transmembrane domain, producing a NotchlC fragment that moves into the nucleus. The cleavage occurs constitutively, giving an activated Notch phenotype, when the protein lacks a specific part of its extracellular domain. The normal intact extracellular domain presumably regulates cleavage in response to ligand binding.
    • (1996) Proc Natl Acad Sci USA
    • Kopan, R.1    Schroeter, E.H.2    Nye, J.S.3    Weintraub, H.4
  • 32
    • 0027386233 scopus 로고
    • Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei
    • Lieber T, Kidd S, Alcamo E, Corbin V, Young MW: Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev 1993, 7:1949-1965.
    • (1993) Genes Dev , vol.7 , pp. 1949-1965
    • Lieber, T.1    Kidd, S.2    Alcamo, E.3    Corbin, V.4    Young, M.W.5
  • 33
    • 0027306001 scopus 로고
    • Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor
    • Rebay I, Fehon RG, Artavanis-Tsakonas S: Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell 1993, 74:319-329.
    • (1993) Cell , vol.74 , pp. 319-329
    • Rebay, I.1    Fehon, R.G.2    Artavanis-Tsakonas, S.3
  • 34
    • 0027219557 scopus 로고
    • Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo
    • Struhl G, Fitzgerald K, Greenwald I: Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 1993, 74:331-345.
    • (1993) Cell , vol.74 , pp. 331-345
    • Struhl, G.1    Fitzgerald, K.2    Greenwald, I.3
  • 35
    • 0027378244 scopus 로고
    • An activated Notch receptor blocks cell fate commitment in the developing Drosophila eye
    • Fortini ME, Rebay I, Caron LA, Artavanis-Tsakonas S: An activated Notch receptor blocks cell fate commitment in the developing Drosophila eye. Nature 1993, 365:555-557.
    • (1993) Nature , vol.365 , pp. 555-557
    • Fortini, M.E.1    Rebay, I.2    Caron, L.A.3    Artavanis-Tsakonas, S.4
  • 36
    • 0027291722 scopus 로고
    • Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats
    • Roehl H, Kimble J: Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature 1993, 364:632-635.
    • (1993) Nature , vol.364 , pp. 632-635
    • Roehl, H.1    Kimble, J.2
  • 37
    • 0027966977 scopus 로고
    • An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells
    • Nye JS, Kopan R, Axel R: An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development 1994, 120:2421-2430.
    • (1994) Development , vol.120 , pp. 2421-2430
    • Nye, J.S.1    Kopan, R.2    Axel, R.3
  • 38
    • 0028171718 scopus 로고
    • The Suppressor of Hairless protein participates in Notch receptor signalling
    • Fortini ME, Artavanis-Tsakonas S: The Suppressor of Hairless protein participates in Notch receptor signalling. Cell 1994, 79:273-282. Notch is shown to bind to Su(H), and Notch activation by Delta in Drosophila cultured S2 cells is shown to lead to a translocation of Su(H) into the nucleus.
    • (1994) Cell , vol.79 , pp. 273-282
    • Fortini, M.E.1    Artavanis-Tsakonas, S.2
  • 39
    • 0029583607 scopus 로고
    • Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H)
    • Tamura K, Taniguchi Y, Minoguchi S, Sakai T, Tun T, Furukawa T, Honjo T: Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H). Curr Biol 1995, 5:1416-1423. Using the yeast two-hybrid system and direct binding assays, the authors show that Notch proteins bind to RBP-Jκ/Su(H) via a short (<50 amino acids) domain of Notch just internal to the transmembrane domain. This domain does not include the CDC10/ankyrin repeats, previously thought to mediate the binding.
    • (1995) Curr Biol , vol.5 , pp. 1416-1423
    • Tamura, K.1    Taniguchi, Y.2    Minoguchi, S.3    Sakai, T.4    Tun, T.5    Furukawa, T.6    Honjo, T.7
  • 40
    • 0342322634 scopus 로고    scopus 로고
    • The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split Complex genes triggered by Notch
    • in press
    • Lecourtois M, Schweisguth F: The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split Complex genes triggered by Notch. Genes Dev 1996, in press. Mutant embryos deprived of maternal as well as zygotic Su(H) show a full-blown neurogenic phenotype and fail to express genes of the E(spl)-C. Su(H) protein binds to regulatory sequences of two genes (m5 and m8) of the E(spl)-C and is required for the activation of their transcription.
    • (1996) Genes Dev
    • Lecourtois, M.1    Schweisguth, F.2
  • 41
    • 12644280833 scopus 로고    scopus 로고
    • Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio
    • in press
    • Jiang Y-J, Brand M, Heisenberg C-P, Beuchle D, Furutani-Seiki M, Kelsh RN, Warga RN, Granato M, Haffter P, Hammerschmidt M et al.: Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development 1996, in press. white tail mutant embryos produce primary neurons in excessive numbers, but in a normal distribution, just as though there has been a failure of lateral inhibition within proneural clusters; for example, at the site in the hindbrain where a normal embryo would generate a single isolated Mauthner neuron, white tail has a cluster of three or four such neurons. There are defects also in the development of somites and in the production of melanocytes (hence the name), and the embryo dies before it is two days old. It remains to be seen whether white tail corresponds to any of the neurogenic genes of Drosophila.
    • (1996) Development
    • Jiang, Y.-J.1    Brand, M.2    Heisenberg, C.-P.3    Beuchle, D.4    Furutani-Seiki, M.5    Kelsh, R.N.6    Warga, R.N.7    Granato, M.8    Haffter, P.9    Hammerschmidt, M.10
  • 43
    • 0025084614 scopus 로고
    • Xotch, the Xenopus homolog of Drosophila Notch
    • Coffman C, Harris W, Kintner C: Xotch, the Xenopus homolog of Drosophila Notch. Science 1990, 249:1438-1441.
    • (1990) Science , vol.249 , pp. 1438-1441
    • Coffman, C.1    Harris, W.2    Kintner, C.3
  • 44
    • 0029023204 scopus 로고
    • Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta
    • Bettenhausen B, Hrabé de Angelis M, Simon D, Guénet J-L, Gossler A: Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development 1995, 121:2407-2418. Describes the cloning and expression pattern of a mouse Delta homologue, Dll1. Expression is seen in various non-neural tissues, as well as in the nervous system.
    • (1995) Development , vol.121 , pp. 2407-2418
    • Bettenhausen, B.1    Hrabé De Angelis, M.2    Simon, D.3    Guénet, J.-L.4    Gossler, A.5
  • 45
    • 0029061491 scopus 로고
    • Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta
    • Chitnis A, Henrique D, Lewis J, Ish-Horowicz D, Kintner C: Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 1995, 375:761-766. A Xenopus homologue of Delta is transiently expressed in nascent primary neurons. Its function is tested by injection of RNA constructs into the two-cell embryo. The results imply that homologues of Notch and Delta control primary neurogenesis in Xenopus by mediating lateral inhibition, whereby each nascent primary neuron prevents its neighbours from becoming primary neurons.
    • (1995) Nature , vol.375 , pp. 761-766
    • Chitnis, A.1    Henrique, D.2    Lewis, J.3    Ish-Horowicz, D.4    Kintner, C.5
  • 46
    • 0029062934 scopus 로고
    • Expression of a Delta homologue in prospective neurons in the chick
    • Henrique D, Adam J, Myat A, Chitnis A, Lewis J, Ish-Horowicz D: Expression of a Delta homologue in prospective neurons in the chick. Nature 1995, 375:787-790. A chick homologue of Delta is described, and the cells in the early CNS that express it are identified as nascent neurons by virtue of their non-proliferative state.
    • (1995) Nature , vol.375 , pp. 787-790
    • Henrique, D.1    Adam, J.2    Myat, A.3    Chitnis, A.4    Lewis, J.5    Ish-Horowicz, D.6
  • 47
    • 0029363136 scopus 로고
    • Vertebrate ligands for Notch
    • Nye JS, Kopan R: Vertebrate ligands for Notch. Curr Biol 1995, 5:966-969.
    • (1995) Curr Biol , vol.5 , pp. 966-969
    • Nye, J.S.1    Kopan, R.2
  • 48
    • 0028950732 scopus 로고
    • Jagged: A mammalian ligand that activates Notch1
    • Lindsell CE, Shawber CJ, Boulter J, Weinmaster G: Jagged: a mammalian ligand that activates Notch1. Cell 1995, 80:909-917. Jagged is a mammalian homologue of the Delta-related gene Serrate, and is expressed in the developing CNS. Experiments with transfected cells in culture demonstrate that, like Delta and Serrate, Jagged can serve as an activating ligand for the Notch signalling pathway.
    • (1995) Cell , vol.80 , pp. 909-917
    • Lindsell, C.E.1    Shawber, C.J.2    Boulter, J.3    Weinmaster, G.4
  • 49
    • 0029925224 scopus 로고    scopus 로고
    • A chick homologue of Serrate, and its relationship with Notch and Delta homologues during central neurogenesis
    • in press
    • Myat A, Henrique D, Ish-Horowicz D, Lewis J: A chick homologue of Serrate, and its relationship with Notch and Delta homologues during central neurogenesis. Dev Biol 1996, in press. Chick homologues of Notch, Delta and Serrate are expressed in the ventricular zone of the neural tube, at late as well as early stages, in a manner suggesting a continuing role in the control of neurogenesis by lateral inhibition. In hindbrain and spinal cord, a curious complementarity is seen between the expression domains of the Serrate and Delta homologues, hinting that they may have partly interchangeable functions.
    • (1996) Dev Biol
    • Myat, A.1    Henrique, D.2    Ish-Horowicz, D.3    Lewis, J.4
  • 50
    • 0028296937 scopus 로고
    • Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system
    • Ishibashi M, Moriyoshi K, Sasai Y, Shiota K, Nakanishi S, Kageyama R: Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J 1994, 13:1799-1805. A retrovirus is used to force expression of the E(spl)-C homologue HES-1 in cells in the ventricular zone of the embryonic mouse CNS. The infected cells, in contrast to controls, fail to leave the ventricular zone and fail to turn into neurons or glia. Neural precursor cells similarly infected in culture fail to differentiate as neurons. Thus, HES-1, like E(spl), inhibits commitment to a neural fate.
    • (1994) EMBO J , vol.13 , pp. 1799-1805
    • Ishibashi, M.1    Moriyoshi, K.2    Sasai, Y.3    Shiota, K.4    Nakanishi, S.5    Kageyama, R.6
  • 51
    • 0029595271 scopus 로고
    • Targeted disruption of mammalian hairy and Enhancer of split homologue-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis and severe neural tube defects
    • Ishibashi M, Ang S-L, Shiota K, Nakanishi S, Kageyama R, Guillemot F: Targeted disruption of mammalian hairy and Enhancer of split homologue-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis and severe neural tube defects. Genes Dev 1995, 9:3136-3148.
    • (1995) Genes Dev , vol.9 , pp. 3136-3148
    • Ishibashi, M.1    Ang, S.-L.2    Shiota, K.3    Nakanishi, S.4    Kageyama, R.5    Guillemot, F.6
  • 52
    • 0026936126 scopus 로고
    • Human homologs of a Drosophila Enhancer of Split gene product define a novel family of nuclear proteins
    • Stifani S, Blaumueller CM, Redhead NJ, Hill RE, Artavanis-Tsakonas S: Human homologs of a Drosophila Enhancer of Split gene product define a novel family of nuclear proteins. Nature Genet 1992, 2:119-127.
    • (1992) Nature Genet , vol.2 , pp. 119-127
    • Stifani, S.1    Blaumueller, C.M.2    Redhead, N.J.3    Hill, R.E.4    Artavanis-Tsakonas, S.5
  • 53
    • 0028811635 scopus 로고
    • TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination
    • Dehni G, Liu Y, Husain J, Stifani S: TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination. Mech Dev 1995, 53:369-381.
    • (1995) Mech Dev , vol.53 , pp. 369-381
    • Dehni, G.1    Liu, Y.2    Husain, J.3    Stifani, S.4
  • 54
    • 0026647098 scopus 로고
    • Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates
    • Schweisguth F, Posakony JW: Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell 1992, 69:1199-1212.
    • (1992) Cell , vol.69 , pp. 1199-1212
    • Schweisguth, F.1    Posakony, J.W.2
  • 56
    • 0028902623 scopus 로고
    • Intrinsic and extrinsic factors regulating vertebrate neurogenesis
    • Calof AL: Intrinsic and extrinsic factors regulating vertebrate neurogenesis. Curr Opin Neurobiol 1995, 5:19-27. A review that takes a broader perspective than the present one, examining the whole system of controls of vertebrate neurogenesis, including proneural and neurogenic genes.
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 19-27
    • Calof, A.L.1
  • 57
    • 0026278894 scopus 로고
    • Rules for the production of sensory cells
    • Lewis J: Rules for the production of sensory cells. Ciba Found Symp 1991, 160:25-39.
    • (1991) Ciba Found Symp , vol.160 , pp. 25-39
    • Lewis, J.1
  • 58
    • 0024745810 scopus 로고
    • Early neurogenesis in Xenopus: The spatiotemporal pattern of proliferation and cell lineages in the embryonic spinal cord
    • Hartenstein V: Early neurogenesis in Xenopus: the spatiotemporal pattern of proliferation and cell lineages in the embryonic spinal cord. Neuron 1989, 3:399-411.
    • (1989) Neuron , vol.3 , pp. 399-411
    • Hartenstein, V.1
  • 59
    • 0028115915 scopus 로고
    • Cell cycles and clonal strings during axis formation of the zebrafish central nervous system
    • Kimmel CB, Warga RM, Kane DA: Cell cycles and clonal strings during axis formation of the zebrafish central nervous system. Development 1994, 120:265-276.
    • (1994) Development , vol.120 , pp. 265-276
    • Kimmel, C.B.1    Warga, R.M.2    Kane, D.A.3
  • 60
    • 0013794128 scopus 로고
    • The development of the spinal cord examined by autoradiography
    • Martin A, Langman J: The development of the spinal cord examined by autoradiography. J Embryol Exp Morphol 1965, 14:25-35.
    • (1965) J Embryol Exp Morphol , vol.14 , pp. 25-35
    • Martin, A.1    Langman, J.2
  • 62
    • 0028822543 scopus 로고
    • Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch
    • Austin CP, Feldman DE, Ida JA, Cepko CL: Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch. Development 1995, 121:3637-3650. Increased numbers of ganglion cells are produced in chick retina when Notch activity is diminished by treatment with antisense oligonucleotides, and decreased numbers are produced when the embryonic retina is infected with a retrovirus carrying a gene for a constitutively active form of Notch. Retinal progenitor cells in vitro are inhibited from differentiating into neurons when co-cultured with Drosophila cells expressing Delta.
    • (1995) Development , vol.121 , pp. 3637-3650
    • Austin, C.P.1    Feldman, D.E.2    Ida, J.A.3    Cepko, C.L.4
  • 63
    • 0028951875 scopus 로고
    • Xotch inhibits cell differentiation in the Xenopus retina
    • Dorsky RI, Rapaport DH, Harris WA: Xotch inhibits cell differentiation in the Xenopus retina. Neuron 1995, 14:487-496.
    • (1995) Neuron , vol.14 , pp. 487-496
    • Dorsky, R.I.1    Rapaport, D.H.2    Harris, W.A.3
  • 64
    • 0029080470 scopus 로고
    • Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis
    • Chenn A, McConnell SK: Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis. Cell 1995, 82:631-641. Time-lapse observation of slice preparations of ferret cortex show that cells emigrating from the proliferative zone are produced by asymmetric cell divisions. Notch-1 protein appears to be segregated into the emigrant daughter cell, although it is not clear what function, if any, the protein has there.
    • (1995) Cell , vol.82 , pp. 631-641
    • Chenn, A.1    McConnell, S.K.2
  • 65
    • 0028203495 scopus 로고
    • Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila
    • Tax FE, Yeargers JJ, Thomas JH: Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila. Nature 1994, 368:150-154.
    • (1994) Nature , vol.368 , pp. 150-154
    • Tax, F.E.1    Yeargers, J.J.2    Thomas, J.H.3
  • 66
    • 0029556908 scopus 로고
    • Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila
    • Couso JP, Knust E, Martinez Arias A: Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila. Curr Biol 1995, 5:1437-1448.
    • (1995) Curr Biol , vol.5 , pp. 1437-1448
    • Couso, J.P.1    Knust, E.2    Martinez Arias, A.3
  • 67
    • 0029585601 scopus 로고
    • Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing
    • Diaz-Benjumea FJ, Cohen SM: Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 1995, 121:4215-4225.
    • (1995) Development , vol.121 , pp. 4215-4225
    • Diaz-Benjumea, F.J.1    Cohen, S.M.2
  • 68
    • 0028348883 scopus 로고
    • The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: Control of cell proliferation
    • Speicher SA, Thomas U, Hinz U, Knust E: The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. Development 1994, 120:535-544.
    • (1994) Development , vol.120 , pp. 535-544
    • Speicher, S.A.1    Thomas, U.2    Hinz, U.3    Knust, E.4
  • 69
    • 0028905887 scopus 로고
    • Serrate expression can functionally replace Delta activity during neuroblast segregation in the Drosophila embryo
    • Gu Y, Hukriede NA, Fleming RJ: Serrate expression can functionally replace Delta activity during neuroblast segregation in the Drosophila embryo. Development 1995, 121:855-865.
    • (1995) Development , vol.121 , pp. 855-865
    • Gu, Y.1    Hukriede, N.A.2    Fleming, R.J.3
  • 70
    • 0027996069 scopus 로고
    • Notch is required for wingless signalling in the epidermis of Drosophila
    • Couso JP, Martinez Arias A: Notch is required for wingless signalling in the epidermis of Drosophila. Cell 1994, 79:259-272.
    • (1994) Cell , vol.79 , pp. 259-272
    • Couso, J.P.1    Martinez Arias, A.2
  • 71
    • 0028071653 scopus 로고
    • Structure/function studies of lin-12/Notch proteins
    • Greenwald I: Structure/function studies of lin-12/Notch proteins. Curr Opin Genet Dev 1994, 4:556-562.
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 556-562
    • Greenwald, I.1
  • 72
    • 0028289647 scopus 로고
    • The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor repeats and is expressed in proliferating neuroepithelium
    • Lardelli M, Dahlstrand J, Lendahl U: The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor repeats and is expressed in proliferating neuroepithelium. Mech Dev 1994, 46:123-136.
    • (1994) Mech Dev , vol.46 , pp. 123-136
    • Lardelli, M.1    Dahlstrand, J.2    Lendahl, U.3
  • 73
    • 0028989016 scopus 로고
    • Notch 1 is required for the coordinate segmentation of somites
    • Conlon RA, Reaume AG, Rossant J: Notch 1 is required for the coordinate segmentation of somites. Development 1995, 121:1533-1545.
    • (1995) Development , vol.121 , pp. 1533-1545
    • Conlon, R.A.1    Reaume, A.G.2    Rossant, J.3
  • 75
    • 0029116848 scopus 로고
    • Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
    • Levitan D, Greenwald I: Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 1995, 377:350-354. A gene identified in C. elegans as a suppressor of a gain-of-function mutation in the Notch homologue lin-12 turns out to be homologous to a human gene implicated in a hereditary form of Alzheimer's disease.
    • (1995) Nature , vol.377 , pp. 350-354
    • Levitan, D.1    Greenwald, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.