Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc

Development

Volumn 124, Issue 15, 1997, Pages 2973-2981

  Fleming, Robert J ^a   Gu, Yi ^a   Hukriede, Neil A ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Drosophila; Fringe; Notch activation; Serrate; Wing development

Indexed keywords

CELL PROTEIN; GENE PRODUCT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FORELIMB; GENE ACTIVATION; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENE LOCATION; GENETIC TRANSCRIPTION; IMAGINAL DISC; LIMB DEVELOPMENT; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CALCIUM-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; INSECT PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; N-ACETYLGLUCOSAMINYLTRANSFERASES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; WING;

ANIMALIA;

EID: 0030845799     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Artavanis-Tsakonas, S. and Simpson, P. (1991). Choosing a cell fate : a view from the Notch locus. Trends Genet. 7, 403-408.
2. Artavanis-Tsakonas, S., Delidakis, C. and Fehon, R. G. (1991). The Notch locus and the cell biology of neuroblast segregation. Ann. Rev. Cell Biol. 7, 427-452.
3. Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E. (1995). Notch signaling. Science 268, 225-232.
4. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
5. Cagan, R. L. and Ready, D. F. (1989). Notch is required for successive cell decisions in the developing Drosophila retina. Genes Dev. 3, 1099-1112.
6. Campos-Ortega, J. A., and Hartenstein, V. (1985). The Embryonic Development of Drosophila melanogaster. Berlin-Heidelberg-New York-Tokyo: Springer-Verlag.
7. Cohen, B., McGuffin, M. E., Pfeifle, C., Segal, D. and Cohen, S. M. (1992). apterous: a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins. Genes Dev. 6, 715-729.
8. Corbin, V., Michelson, A. M., Abmayr, S. M., Neel, V., Alcamo, E., Maniatis, T. and Young, M. W. (1991). A role for the Drosophila neurogenic genes in mesoderm differentiation. Cell 67, 311-323.
9. Couso, J. P. and Martinez-Arias, A. (1994). Notch is required for wingless signalling in the epidermis of Drosophila. Cell 79, 259-272.
10. Couso, J. P., Knust, E. and Martinez-Arias, A. (1995). Serrate and wingless cooperate to induce vestigial gene expression and wing formation. Current Biology 5, 1437-1448.
11. De Celis, J. F., Garcia-Bellido, A. and Bray, S. J. (1996). Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122, 359-369.
12. Diaz-Benjumea. F. J. and Cohen, S. M. (1995). Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.
13. Doherty, D., Feger, G., Younger-Shepard, S., Jan, L. Y. and Jan, Y. N. (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434.
14. Fehon, R. G., Kooh, P. J., Rebay, I., Regan, C. L., Xu, T., Muskavitch, M. A. T. and Artavanis-Tsakonas, S. (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61, 523-534.
15. Fehon, R. G., Johansen, K., Rebay, I. and Artavanis-Tsakonas, S. (1991). Complex spatial and temporal regulation of Notch expression during embryonic and imaginal development of Drosophila: implications for Notch function. J. Cell Biol. 113, 657-669.
16. Fleming, R. J., Scottgale, T. N., Diederich, R. J. and Artavanis-Tsakonas, S. (1990). The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster. Genes Dev. 4, 2188-2201.
17. Gu, Y., Hukriede, N. A. and Fleming, R. J. (1995). Serrate expression can functionally replace Delta activity during neuroblast segregation in the Drosophila embryo. Development 121, 855-865.
18. Hartenstein, V. and Posakony, J. W. (1990). A dual function of the Notch gene in Drosophila sensillum development. Dev. Biol. 142, 13-30.
19. Hartenstein, A. Y., Rugendorff, A., Tepass, U. and Hartenstein, V. (1992). The function of the neurogenic genes during epithelial development in the Drosophila embryo. Development 116, 1203-1220.
20. Heitzler, P. and Simpson, P. (1991). The choice of cell fate in the epidermis of Drosophila. Cell 64, 1083-1092.
21. Heitzler, P. and Simpson, P. (1993). Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions. Development 117, 1113-1123.
22. Hinz, U., Giebel, B. and Campos-Ortega, J. (1994). The basic-helix-loophelix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes. Cell 76, 77-87.
23. Irvine, K. and Weischaus, E. (1994). fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79, 595-606.
24. Jönsson, F. and Knust, E. (1996). Distinct functions of the Drosophila genes Serrate and Delta revealed by ectopic expression during wing development. Dev. Genes. Evol. 206, 91-101.
25. Kim, J., Irvine, K. D. and Carroll, S. B. (1995). Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802.
26. Kim, J., Sebring, A., Esch, J., Kraus, M. E., Vorwerk, K., Magee, J. and Carroll, S. B. (1996). Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382, 133-138.
27. Kooh, P. J., Fehon, R. G. and Muskavitch, M. A. (1993). Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117, 493-507.
28. Kopczynski, C. C., Alton, A. K., Fechtel, K., Kooh, P. J. and Muskavitch, M. A. T. (1988). Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates. Genes Dev. 2, 1723-1735.
29. Larkin, M. K., Holder, K., Yost, C., Giniger, E. and Ruohola-Baker, H. (1996). Expression of constitutively activated Notch arrests follicle cells at a precursor stage during Drosophila oogenesis and disrupts the anterior-posterior axis of the oocyte. Development 122, 339-3650.
30. Lindsley, D. L. and Zimm, G. G. (1992). The Genome of Drosophila melanogaster. San Diego, CA: Academic Press.
31. Neumann, C. J. and Cohen. S. M. (1996). A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing. Development 122, 3477-3485.
32. Panin, V. M., Papayannopoulos, V., Wilson, R. and Irvine, K. D. (1997). fringe modulates Notch-ligand interactions. Nature (in press).
33. Piccolo, S., Sasai, Y., Lu, B. and De Robertis, E. M. (1996). Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86, 589-598.
34. Rebay, I., Fleming, R. J., Fehon, R. G., Cherbas, L., Cherbas, P. and Artavanis-Tsakonas, S. (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67, 687-699.
35. Rulifson, E. J. and Blair. S. S. (1995). Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila. Development 121, 2813-2824.
36. Ruohola, H., Bremer, K. A., Baker, D., Swedlow, J. R., Jan, L. Y. and Jan, Y. N. (1991). Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila. Cell 66, 433-449.
37. Sanger, F., Nicklen, S. and Coulson, A. R. (1977). DNA sequencing with chain termination inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
38. Speicher, S. A., Thomas, U., Hinz, U. and Knust, E. (1994). The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. Development 120, 535-544.
39. Spradling, A. C. (1986). P element-mediated transformation. In Drosophila: A Practical Approach, (ed. D. B. Roberts). pp. 175-197. Oxford, UK: IRL Press.
40. Tax, F. E., Yeargers, J. J. and Thomas, J. H. (1994). Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila. Nature 368, 150-154.
41. Thomas, U., Speicher, S. A. and Knust, E. (1991). The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs. Development 111, 749-762.
42. Vässin, H., Bremer, K. A., Knust, E. and Campos-Ortega, J. A. (1987). The neurogenic gene Delta of D. melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats. EMBO J. 6, 3431-3440.
43. Welshons, W. J. (1965). Analysis of a gene in Drosophila. Science 150, 1122-1129.
44. Wilcox, M., Brown, N., Piovant, M., Smith, R. J. and White, R. A. H. (1984). The position-specific antigens are a family of cell surface glycoprotein complexes. EMBO J. 3, 2307-2313.
45. Williams, J. A., Paddock, S. W., Vorwerk, K. and Carroll, S. B. (1994). Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary. Nature 368, 299-305.
46. Xu, T., Caron, L. A., Fehon, R. G. and Artavanis-Tsakonas, S. (1992). The involvement of the Notch locus in Drosophila oogenesis. Development 115, 913-922.
47. Yuan, Y. P., Schultz, J., Mlodzik, M. and Bork, P. (1997). Secreted Fringelike signaling molecules may be glycosyltransferases. Cell 88, 9-11.
48. Zimmerman, L. B., De Jesús-Escobar, J. M. and Harland, R. M. (1996). The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606.