메뉴 건너뛰기




Volumn 383, Issue 7-8, 2002, Pages 1045-1057

Human tissue kallikreins: A new enzymatic cascade pathway?

Author keywords

Alzheimer's disease; Cascade activation system; Enzymatic activity; Kallikrein; Serine proteases; Tumor markers

Indexed keywords

CHYMOTRYPSIN; DNA; ENZYME PRECURSOR; MESSENGER RNA; PLASMA KALLIKREIN; PROTEINASE; SERINE PROTEINASE; STEROID HORMONE; TISSUE KALLIKREIN; TRYPSIN;

EID: 0036661263     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2002.113     Document Type: Review
Times cited : (90)

References (131)
  • 1
    • 0023622310 scopus 로고
    • The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein
    • Akiyama, K., Nakamura, T., Iwanaga, S., and Hara, M. (1987). The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein. FEBS Lett. 225, 168-172.
    • (1987) FEBS Lett , vol.225 , pp. 168-172
    • Akiyama, K.1    Nakamura, T.2    Iwanaga, S.3    Hara, M.4
  • 2
    • 0029844185 scopus 로고    scopus 로고
    • A novel protease homolog differentially expressed in breast and ovarian cancer
    • Anisowicz, A., Sotiropoulou, G., Stenman, G., Mok, S. C., and Sager, R. (1996). A novel protease homolog differentially expressed in breast and ovarian cancer. Mol. Med. 2, 624-636.
    • (1996) Mol. Med , vol.2 , pp. 624-636
    • Anisowicz, A.1    Sotiropoulou, G.2    Stenman, G.3    Mok, S.C.4    Sager, R.5
  • 3
    • 0023515093 scopus 로고
    • Organization of the gene for human factor XI
    • Asakai, R., Davie, E. W. and Chung, D. W. (1987). Organization of the gene for human factor XI. Biochemistry 26, 7221-7228.
    • (1987) Biochemistry , vol.26 , pp. 7221-7228
    • Asakai, R.1    Davie, E.W.2    Chung, D.W.3
  • 4
    • 0026556434 scopus 로고
    • Bioregulation of kinins: Kallikreins, kininogens, and kininases
    • Bhoola, K. D., Figueroa, C. D., and Worthy, K. (1992). Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol. Rev. 44, 1-80.
    • (1992) Pharmacol. Rev , vol.44 , pp. 1-80
    • Bhoola, K.D.1    Figueroa, C.D.2    Worthy, K.3
  • 6
    • 0033569724 scopus 로고    scopus 로고
    • Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation
    • Brattsand, M., and Egelrud, T. (1999). Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation. J. Biol. Chem. 274, 30033-30040.
    • (1999) J. Biol. Chem , vol.274 , pp. 30033-30040
    • Brattsand, M.1    Egelrud, T.2
  • 7
    • 0028857265 scopus 로고
    • Substrate specificity of tissue kallikreins: Importance of an extended interaction site
    • Brillard-Bourdet, M., Moreau, T., and Gauthier, F. (1995). Substrate specificity of tissue kallikreins: importance of an extended interaction site. Biochim. Biophys. Acta 1246, 47-52.
    • (1995) Biochim. Biophys. Acta , vol.1246 , pp. 47-52
    • Brillard-Bourdet, M.1    Moreau, T.2    Gauthier, F.3
  • 8
    • 0031920589 scopus 로고    scopus 로고
    • Relative activity and specificity of promoters from prostate-expressed genes
    • Brookes, D. E., Zandvliet, D., Waft, F., Russell, P, J., and Molloy, P. L. (1998). Relative activity and specificity of promoters from prostate-expressed genes. Prostate 35, 18-26.
    • (1998) Prostate , vol.35 , pp. 18-26
    • Brookes, D.E.1    Zandvliet, D.2    Waft, F.3    Russell, P.J.4    Molloy, P.L.5
  • 9
    • 0035572756 scopus 로고    scopus 로고
    • Identification and molecular characterization of five novel kallikrein gene 13 (KLK13;KLK-L4) splice variants: Differential expression in human testis and testicular cancer
    • Chang, A., Yousef, G. M., Jung, K., Meyts, E. R., and Diamanids, E. P. (2001). Identification and molecular characterization of five novel kallikrein gene 13 (KLK13;KLK-L4) splice variants: differential expression in human testis and testicular cancer. Anticancer Res. 21, 147-152.
    • (2001) Anticancer Res , vol.21 , pp. 147-152
    • Chang, A.1    Yousef, G.M.2    Jung, K.3    Meyts, E.R.4    Diamanids, E.P.5
  • 10
    • 0037029685 scopus 로고    scopus 로고
    • Human kallikrein gene 13 (KLK13) expression by quantitative RT-PCR: An independent indicator of favorable prognosis in breast cancer
    • in press
    • Chang, A., Yousef, G. M., Scorilas, A., Grass, L., Sismondi, P., Ponzone, R., and Diamandis, E. P. (2002). Human kallikrein gene 13 (KLK13) expression by quantitative RT-PCR: an independent indicator of favorable prognosis in breast cancer. Br. J. Cancer, in press.
    • (2002) Br. J. Cancer
    • Chang, A.1    Yousef, G.M.2    Scorilas, A.3    Grass, L.4    Sismondi, P.5    Ponzone, R.6    Diamandis, E.P.7
  • 11
    • 0028491184 scopus 로고
    • Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues
    • Chen, L. M., Murray, S. R., Chai, K. X., Chao, L., and Chao, J., (1994). Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues. Braz. J. Med. Biol. Res. 27, 1829-1838.
    • (1994) Braz. J. Med. Biol. Res , vol.27 , pp. 1829-1838
    • Chen, L.M.1    Murray, S.R.2    Chai, K.X.3    Chao, L.4    Chao, J.5
  • 12
    • 0025671852 scopus 로고
    • Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors
    • Christensson, A., Laurell, C. B., and Lilja, H. (1990). Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors. Eur. J. Biochem. 194, 755-763.
    • (1990) Eur. J. Biochem , vol.194 , pp. 755-763
    • Christensson, A.1    Laurell, C.B.2    Lilja, H.3
  • 14
    • 0028078676 scopus 로고
    • Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen
    • Christensson, A., and Lilja, H. (1994). Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen. Eur. J. Biochem. 220, 45-53.
    • (1994) Eur. J. Biochem , vol.220 , pp. 45-53
    • Christensson, A.1    Lilja, H.2
  • 15
    • 0001891997 scopus 로고    scopus 로고
    • The molecular biology of the kallikreins and their roles in inflammation
    • S. Farmer, ed. (New York, USA: Academic Press)
    • Clements, J. (1997). The molecular biology of the kallikreins and their roles in inflammation. In: The Kinin System, S. Farmer, ed. (New York, USA: Academic Press), pp. 71-97.
    • (1997) The Kinin System , pp. 71-97
    • Clements, J.1
  • 16
    • 0035115850 scopus 로고    scopus 로고
    • The expanded human kallikrein (KLK) gene family: Genomic organisation, tissue-specific expression and potential functions
    • Clements, J., Hooper, J., Dong, Y., and Harvey, T. (2001). The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions. Biol. Chem. 382, 5-14.
    • (2001) Biol. Chem , vol.382 , pp. 5-14
    • Clements, J.1    Hooper, J.2    Dong, Y.3    Harvey, T.4
  • 17
    • 0029865240 scopus 로고    scopus 로고
    • Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter
    • Cleutjens, K. B., van Eekelen, C. C., van der Korput, H. A., Brinkmann, A. O., and Trapman, J. (1996). Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter. J. Biol. Chem. 271, 6379-6388.
    • (1996) J. Biol. Chem , vol.271 , pp. 6379-6388
    • Cleutjens, K.B.1    van Eekelen, C.C.2    van der Korput, H.A.3    Brinkmann, A.O.4    Trapman, J.5
  • 18
    • 0031017102 scopus 로고    scopus 로고
    • An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter
    • Cleutjens, K. B., van der Korput, H. A., van Eekelen, C. C., van Rooij, H. C., Faber, P. W., and Trapman, J. (1997). An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter. Mol. Endocrinol. 11, 148-161.
    • (1997) Mol. Endocrinol , vol.11 , pp. 148-161
    • Cleutjens, K.B.1    van der Korput, H.A.2    van Eekelen, C.C.3    van Rooij, H.C.4    Faber, P.W.5    Trapman, J.6
  • 19
    • 0026753517 scopus 로고
    • Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma
    • Cohen, P., Graves, H. C., Peehl, D. M., Kamarei, M., Giudice, L.C., and Rosenfeld, R.G. (1992). Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J. Clin. Endocrinol. Metab. 75, 1046-1053.
    • (1992) J. Clin. Endocrinol. Metab , vol.75 , pp. 1046-1053
    • Cohen, P.1    Graves, H.C.2    Peehl, D.M.3    Kamarei, M.4    Giudice, L.C.5    Rosenfeld, R.G.6
  • 20
    • 0000228203 scopus 로고
    • Atlas of protein sequence and structure
    • Dayhoff, M. O. (1978). Atlas of protein sequence and structure. Natl. Biomed. Res. Found. 5, 79-81.
    • (1978) Natl. Biomed. Res. Found , vol.5 , pp. 79-81
    • Dayhoff, M.O.1
  • 21
    • 0035399462 scopus 로고    scopus 로고
    • Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing
    • Denmeade, S. R., Lovgren, J., Khan, S. R., Lilja, H., and Isaacs, J. T. (2001). Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing. Prostate 48, 122-126.
    • (2001) Prostate , vol.48 , pp. 122-126
    • Denmeade, S.R.1    Lovgren, J.2    Khan, S.R.3    Lilja, H.4    Isaacs, J.T.5
  • 22
    • 0030458254 scopus 로고    scopus 로고
    • Potential involvement of kallikrein hK2 in the hydrolysis of the human seminal vesicle proteins after ejaculation
    • Deperthes, D., Frenette, G., Brillard-Bourdet, M., Bourgeois, L., Gauthier, F., Tremblay, R. R., and Dube, J. Y. (1996). Potential involvement of kallikrein hK2 in the hydrolysis of the human seminal vesicle proteins after ejaculation. J. Androl. 17, 659-665.
    • (1996) J. Androl , vol.17 , pp. 659-665
    • Deperthes, D.1    Frenette, G.2    Brillard-Bourdet, M.3    Bourgeois, L.4    Gauthier, F.5    Tremblay, R.R.6    Dube, J.Y.7
  • 23
    • 0035187307 scopus 로고    scopus 로고
    • Analysis of normal epitheliall cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer
    • Dhar, S., Bhargava, R., Yunes, M., Li, B., Goyal, J., Naber, S. P., Wazer, D. E., and Band, V. (2001). Analysis of normal epitheliall cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer. Clin. Cancer Res. 7, 3393-3398.
    • (2001) Clin. Cancer Res , vol.7 , pp. 3393-3398
    • Dhar, S.1    Bhargava, R.2    Yunes, M.3    Li, B.4    Goyal, J.5    Naber, S.P.6    Wazer, D.E.7    Band, V.8
  • 24
    • 0031656568 scopus 로고    scopus 로고
    • Prostate-specific antigen-its usefulness in clinical medicine
    • Diamandis, E. P. (1998). Prostate-specific antigen-its usefulness in clinical medicine. Trends Endocrinol. Metab. 9, 310-316.
    • (1998) Trends Endocrinol. Metab , vol.9 , pp. 310-316
    • Diamandis, E.P.1
  • 25
    • 0035557506 scopus 로고    scopus 로고
    • Human tissue kallikrein gene family: A rich source of novel disease biomarkers
    • Diamandis, E. P., and Yousef, G. M. (2001). Human tissue kallikrein gene family:a rich source of novel disease biomarkers. Expert Rev. Mol. Diagn. 1, 182-190.
    • (2001) Expert Rev. Mol. Diagn , vol.1 , pp. 182-190
    • Diamandis, E.P.1    Yousef, G.M.2
  • 28
    • 0034543474 scopus 로고    scopus 로고
    • Human kallikrein 6 (zyme/protease M/neurosin): A new serum biomarker of ovarian carcinoma
    • Diamandis, E. P., Yousef, G. M., Soosaipillai, A. R., and Bunting, P. (2000c). Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma. Clin. Biochem. 33, 579-583.
    • (2000) Clin. Biochem , vol.33 , pp. 579-583
    • Diamandis, E.P.1    Yousef, G.M.2    Soosaipillai, A.R.3    Bunting, P.4
  • 29
    • 0033778286 scopus 로고    scopus 로고
    • Immunofluorometric assay of human kallikrein 6 (zyme/protease M/neurosin) and preliminary clinical applications
    • Diamandis, E. P., Yousef, G. M., Soosaipillai, A. R., Grass, L., Porter, A., Little, S., and Sotiropoulou, G. (2000d). Immunofluorometric assay of human kallikrein 6 (zyme/protease M/neurosin) and preliminary clinical applications. Clin. Biochem. 33, 369-375.
    • (2000) Clin. Biochem , vol.33 , pp. 369-375
    • Diamandis, E.P.1    Yousef, G.M.2    Soosaipillai, A.R.3    Grass, L.4    Porter, A.5    Little, S.6    Sotiropoulou, G.7
  • 32
    • 0025017927 scopus 로고
    • The dependence of detergent-induced cell dissociation in non-palmo-plantar stratum corneum on endogenous proteolysis
    • Egelrud, T., and Lundstrom, A. (1990). The dependence of detergent-induced cell dissociation in non-palmo-plantar stratum corneum on endogenous proteolysis. J. Invest. Dermatol. 95, 456-459.
    • (1990) J. Invest. Dermatol , vol.95 , pp. 456-459
    • Egelrud, T.1    Lundstrom, A.2
  • 33
    • 0023655293 scopus 로고
    • Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus
    • Evans, B. A., Drinkwater, C. C., and Richards, R. I. (1987). Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus. J. Biol. Chem. 262, 8027-8034.
    • (1987) J. Biol. Chem , vol.262 , pp. 8027-8034
    • Evans, B.A.1    Drinkwater, C.C.2    Richards, R.I.3
  • 35
    • 0035132653 scopus 로고    scopus 로고
    • Molecular analysis of the prostate-specific antigen upstream gene enhancer
    • Farmer, G., Connolly, E. S., Jr., Mocco, J., and Freedman, L. P. (2001). Molecular analysis of the prostate-specific antigen upstream gene enhancer. Prostate 46, 76-85.
    • (2001) Prostate , vol.46 , pp. 76-85
    • Farmer, G.1    Connolly E.S., Jr.2    Mocco, J.3    Freedman, L.P.4
  • 36
    • 0022298158 scopus 로고
    • Nucleotide sequence of cloned cDNA for human pancreatic kallikrein
    • Fukushima, D., Kitamura, N., and Nakanishi, S. (1985). Nucleotide sequence of cloned cDNA for human pancreatic kallikrein. Biochemistry 24, 8037-8043.
    • (1985) Biochemistry , vol.24 , pp. 8037-8043
    • Fukushima, D.1    Kitamura, N.2    Nakanishi, S.3
  • 37
    • 0032212444 scopus 로고    scopus 로고
    • The role for NES1 serine protease as a novel tumor suppressor
    • Goyal, J., Smith, K. M., Cowan, J. M., Wazer, D. E., Lee, S. W., and Band, V. (1998). The role for NES1 serine protease as a novel tumor suppressor. Cancer Res. 58, 4782-4786.
    • (1998) Cancer Res , vol.58 , pp. 4782-4786
    • Goyal, J.1    Smith, K.M.2    Cowan, J.M.3    Wazer, D.E.4    Lee, S.W.5    Band, V.6
  • 38
    • 0015254063 scopus 로고
    • Epidermal turnover time are-examination
    • Halprin, K. M. (1972). Epidermal turnover time are-examination. Br. J. Dermatol. 86, 14-19.
    • (1972) Br. J. Dermatol , vol.86 , pp. 14-19
    • Halprin, K.M.1
  • 39
    • 0027956112 scopus 로고
    • Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase
    • Hansson, L., Stromqvist, M., Backman, A., Wallbrandt, P., Carlstein, A., and Egelrud, T. (1994). Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase. J. Biol. Chem. 269, 19420-19426.
    • (1994) J. Biol. Chem , vol.269 , pp. 19420-19426
    • Hansson, L.1    Stromqvist, M.2    Backman, A.3    Wallbrandt, P.4    Carlstein, A.5    Egelrud, T.6
  • 41
    • 0033564485 scopus 로고    scopus 로고
    • Molecular cloning and expression of an alternative hKLK3 transcript coding for a variant protein of prostate-specific antigen
    • Heuze, N., Olayat, S., Gutman, N., Zani, M. L., and Courty, Y. (1999). Molecular cloning and expression of an alternative hKLK3 transcript coding for a variant protein of prostate-specific antigen. Cancer Res. 59, 2820-2824.
    • (1999) Cancer Res , vol.59 , pp. 2820-2824
    • Heuze, N.1    Olayat, S.2    Gutman, N.3    Zani, M.L.4    Courty, Y.5
  • 42
    • 0035310127 scopus 로고    scopus 로고
    • Identification and characterization of klk14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle
    • Hooper, J. D., Bui, L. T., Rae, F. K., Harvey, T. J., Myers, S. A., Ashworth, L. K., and Clements, J. A. (2001). Identification and characterization of klk14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle. Genomics 73, 117-122.
    • (2001) Genomics , vol.73 , pp. 117-122
    • Hooper, J.D.1    Bui, L.T.2    Rae, F.K.3    Harvey, T.J.4    Myers, S.A.5    Ashworth, L.K.6    Clements, J.A.7
  • 43
    • 0034643918 scopus 로고    scopus 로고
    • Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors
    • Hu, J. C., Zhang, C., Sun, X., Yang, Y., Cao, X., Ryu, O., and Simmer, J. P. (2000). Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors. Gene 251, 1-8.
    • (2000) Gene , vol.251 , pp. 1-8
    • Hu, J.C.1    Zhang, C.2    Sun, X.3    Yang, Y.4    Cao, X.5    Ryu, O.6    Simmer, J.P.7
  • 44
    • 0033520426 scopus 로고    scopus 로고
    • Cooperative assembly of androgen receptor into a nucleoprotein complex that regulates the prostate-specific antigen enhancer
    • Huang, W., Shostak, Y., Tarr, P., Sawyers, C., and Carey, M. (1999). Cooperative assembly of androgen receptor into a nucleoprotein complex that regulates the prostate-specific antigen enhancer. J. Biol. Chem. 274, 25756-25768.
    • (1999) J. Biol. Chem , vol.274 , pp. 25756-25768
    • Huang, W.1    Shostak, Y.2    Tarr, P.3    Sawyers, C.4    Carey, M.5
  • 45
    • 0000057945 scopus 로고    scopus 로고
    • Alteration of the hormonal bioactivity of parathyroid hormone-related protein (PTHrP) as a result of limited proteolysis by prostate-specific antigen
    • Iwamura, M., Hellman, J., Cockett, A. T., LiIja, H. and Gershagen, S. (1996). Alteration of the hormonal bioactivity of parathyroid hormone-related protein (PTHrP) as a result of limited proteolysis by prostate-specific antigen. Urology 48, 317-325.
    • (1996) Urology , vol.48 , pp. 317-325
    • Iwamura, M.1    Hellman, J.2    Cockett, A.T.3    LiIja, H.4    Gershagen, S.5
  • 46
    • 0031956299 scopus 로고    scopus 로고
    • Crystal structure of recombinant human tissue kallikrein at 2.0 Å resolution
    • Katz, B. A., Liu, B., Barnes, M. and Springman, E. B. (1998). Crystal structure of recombinant human tissue kallikrein at 2.0 Å resolution. Protein Sci. 7, 875-885.
    • (1998) Protein Sci , vol.7 , pp. 875-885
    • Katz, B.A.1    Liu, B.2    Barnes, M.3    Springman, E.B.4
  • 47
    • 0031956497 scopus 로고    scopus 로고
    • Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes
    • Khan, A. R., and James, M. N. (1998). Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes. Protein Sci. 7, 815-836.
    • (1998) Protein Sci , vol.7 , pp. 815-836
    • Khan, A.R.1    James, M.N.2
  • 48
    • 0027274805 scopus 로고
    • Mitogenic response of osteoblast cells to prostate-specific antigen suggests an activation of latent TGF-β and a proteolytic modulation of cell adhesion receptors
    • Killian, C. S., Corral, D. A., Kawinski, E., and Constantine, R. I. (1993). Mitogenic response of osteoblast cells to prostate-specific antigen suggests an activation of latent TGF-β and a proteolytic modulation of cell adhesion receptors. Biochem. Biophys. Res. Commun. 192, 940-947.
    • (1993) Biochem. Biophys. Res. Commun , vol.192 , pp. 940-947
    • Killian, C.S.1    Corral, D.A.2    Kawinski, E.3    Constantine, R.I.4
  • 50
    • 0034837770 scopus 로고    scopus 로고
    • Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the kallikrein family: Intracellular localization, alternative cDNA forms, and regulation by multiple hormones
    • Korkmaz, K. S., Korkmaz, C. G., Pretlow, T. G. and Saatcioglu, F. (2001). Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the kallikrein family: intracellular localization, alternative cDNA forms, and regulation by multiple hormones. DNA Cell Biol. 20, 435-445.
    • (2001) DNA Cell Biol , vol.20 , pp. 435-445
    • Korkmaz, K.S.1    Korkmaz, C.G.2    Pretlow, T.G.3    Saatcioglu, F.4
  • 51
    • 0030877244 scopus 로고    scopus 로고
    • Expression of pro form of prostate-specific antigen by mammalian cells and its conversion to mature, active form by human kallikrein 2
    • Kumar, A., Mikolajczyk, S. D., Goel, A. S., Millar, L. S. and Saedi, M. S. (1997). Expression of pro form of prostate-specific antigen by mammalian cells and its conversion to mature, active form by human kallikrein 2. Cancer Res. 57, 3111-3114.
    • (1997) Cancer Res , vol.57 , pp. 3111-3114
    • Kumar, A.1    Mikolajczyk, S.D.2    Goel, A.S.3    Millar, L.S.4    Saedi, M.S.5
  • 52
    • 0022357088 scopus 로고
    • A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle protein
    • Lilja, H. (1985). A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle protein. J. Clin. Invest. 76, 1899-1903.
    • (1985) J. Clin. Invest , vol.76 , pp. 1899-1903
    • Lilja, H.1
  • 54
    • 0029901712 scopus 로고    scopus 로고
    • Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression
    • Liu, X. L., Wazer, D. E., Watanabe, K., and Band, V. (1996). Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression. Cancer Res. 56, 3371-3379.
    • (1996) Cancer Res , vol.56 , pp. 3371-3379
    • Liu, X.L.1    Wazer, D.E.2    Watanabe, K.3    Band, V.4
  • 55
    • 0031577554 scopus 로고    scopus 로고
    • Activation of the zymogen form of prostate-specific antigen by human glandular kallikrein 2
    • Lovgren, J., Rajakoski, K., Karp, M., Lundwall, A., and Lilja, H. (1997). Activation of the zymogen form of prostate-specific antigen by human glandular kallikrein 2. Blochem. Biophys. Res. Commun. 238, 549-555.
    • (1997) Blochem. Biophys. Res. Commun , vol.238 , pp. 549-555
    • Lovgren, J.1    Rajakoski, K.2    Karp, M.3    Lundwall, A.4    Lilja, H.5
  • 57
    • 0024333883 scopus 로고
    • Characterization of the gene for prostate-specific antigen, a human glandular kallikrein
    • Lundwall, A. (1989). Characterization of the gene for prostate-specific antigen, a human glandular kallikrein. Biochem. Biophys. Res. Commun. 161, 1151-1159.
    • (1989) Biochem. Biophys. Res. Commun , vol.161 , pp. 1151-1159
    • Lundwall, A.1
  • 59
    • 0035082050 scopus 로고    scopus 로고
    • Human kallikrein 10: A novel tumor marker for ovarian carcinoma?
    • Luo, L., Bunting, P., Scorilas, A., and Diamandis, E. P. (2001a). Human kallikrein 10: a novel tumor marker for ovarian carcinoma? Clin. Chim. Acta 306, 111-118.
    • (2001) Clin. Chim. Acta , vol.306 , pp. 111-118
    • Luo, L.1    Bunting, P.2    Scorilas, A.3    Diamandis, E.P.4
  • 60
    • 0035134145 scopus 로고    scopus 로고
    • Immunofluorometric assay of human kallikrein 10 and its identification in biological fluids and tissues
    • Luo, L. Y., Grass, L., Howarth, D. J., Thibault, R., Ong, H., and Diamandis, E. P. (2001b). Immunofluorometric assay of human kallikrein 10 and its identification in biological fluids and tissues. Clin. Chem. 47, 237-246.
    • (2001) Clin. Chem , vol.47 , pp. 237-246
    • Luo, L.Y.1    Grass, L.2    Howarth, D.J.3    Thibault, R.4    Ong, H.5    Diamandis, E.P.6
  • 62
    • 0034938562 scopus 로고    scopus 로고
    • Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue
    • Luo, L. Y., Rajpert-De Meyts, E. R., Jung, K., and Diamandis, E. P. (2001d). Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue. Br. J. Cancer 85, 220-224.
    • (2001) Br. J. Cancer , vol.85 , pp. 220-224
    • Luo, L.Y.1    Rajpert-De Meyts, E.R.2    Jung, K.3    Diamandis, E.P.4
  • 64
  • 65
    • 0032427433 scopus 로고    scopus 로고
    • Tissue kallikreins: Structure, regulation, and participation in mammalian physiology and disease
    • Margolius, H. S. (1998). Tissue kallikreins: structure, regulation, and participation in mammalian physiology and disease. Clin. Rev. Allergy Immunol. 16, 337-349.
    • (1998) Clin. Rev. Allergy Immunol , vol.16 , pp. 337-349
    • Margolius, H.S.1
  • 66
    • 0020533545 scopus 로고
    • Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides
    • Mason, A. J., Evans, B. A., Cox, D. R., Shine, J. and Richards, R. I. (1983). Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Nature 303, 300-307.
    • (1983) Nature , vol.303 , pp. 300-307
    • Mason, A.J.1    Evans, B.A.2    Cox, D.R.3    Shine, J.4    Richards, R.I.5
  • 67
    • 0034751918 scopus 로고    scopus 로고
    • Mouse testicular leydig cells express klk21, a tissue kallikrein that cleaves fibronectin and igf-binding protein-3
    • Matsui, H. and Takahashi, T. (2001). Mouse testicular leydig cells express klk21, a tissue kallikrein that cleaves fibronectin and igf-binding protein-3. Endocrinology 142, 4918-4929.
    • (2001) Endocrinology , vol.142 , pp. 4918-4929
    • Matsui, H.1    Takahashi, T.2
  • 68
    • 0033559559 scopus 로고    scopus 로고
    • A novel form of human neuropsin, a brain-related serine protease, is generated by alternative splicing and is expressed preferentially in human adult brain
    • Mitsui, S., Tsuruoka, N., Yamashiro, K., Nakazato, H. and Yamaguchi, N. (1999). A novel form of human neuropsin, a brain-related serine protease, is generated by alternative splicing and is expressed preferentially in human adult brain. Eur. J. Biochem. 260, 627-634.
    • (1999) Eur. J. Biochem , vol.260 , pp. 627-634
    • Mitsui, S.1    Tsuruoka, N.2    Yamashiro, K.3    Nakazato, H.4    Yamaguchi, N.5
  • 69
    • 0034668808 scopus 로고    scopus 로고
    • cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20)
    • Mitsui, S., Okui, A., Kominami, K., Uemura, H. and Yamaguchi, N. (2000a). cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20). Biochim. Biophys. Acta 1494, 206-210.
    • (2000) Biochim. Biophys. Acta , vol.1494 , pp. 206-210
    • Mitsui, S.1    Okui, A.2    Kominami, K.3    Uemura, H.4    Yamaguchi, N.5
  • 70
    • 0034720485 scopus 로고    scopus 로고
    • A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate
    • Mitsui, S., Yamada, T., Okui, A., Kominami, K., Uemura, H. and Yamaguchi, N. (2000b). A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate. Biochem. Biophys. Res. Commun. 272, 205-211.
    • (2000) Biochem. Biophys. Res. Commun , vol.272 , pp. 205-211
    • Mitsui, S.1    Yamada, T.2    Okui, A.3    Kominami, K.4    Uemura, H.5    Yamaguchi, N.6
  • 71
    • 0025339115 scopus 로고
    • Kallikrein multigene families and the regulation of their expression
    • Murray, S. R., Chao, J., Lin, F. K. and Chao, L. (1990). Kallikrein multigene families and the regulation of their expression. J. Cardiovasc. Pharmacol. 15, S7-S16.
    • (1990) J. Cardiovasc. Pharmacol , vol.15
    • Murray, S.R.1    Chao, J.2    Lin, F.K.3    Chao, L.4
  • 72
    • 0027170653 scopus 로고
    • Androgen induction of a human prostate-specific kallikrein, hKLK2: Characterization of an androgen response element in the 5′ promoter region of the gene
    • Murtha, P., Tindall, D. J. and Young, C. Y. (1993). Androgen induction of a human prostate-specific kallikrein, hKLK2: characterization of an androgen response element in the 5′ promoter region of the gene. Biochemistry 32, 6459-6464.
    • (1993) Biochemistry , vol.32 , pp. 6459-6464
    • Murtha, P.1    Tindall, D.J.2    Young, C.Y.3
  • 73
    • 0035008951 scopus 로고    scopus 로고
    • Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE
    • Myers, S. A. and Clements, J. A. (2001). Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE. J. Clin. Endocrinol. Metab. 86, 2323-2326.
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 2323-2326
    • Myers, S.A.1    Clements, J.A.2
  • 74
    • 0035885242 scopus 로고    scopus 로고
    • Alternative splicing isoforms of hippostasin (PRSS20/KLK11) in prostate cancer cell lines
    • in press
    • Nakamura, T., Mitsui, S., Okui, A., Kominami, K., Nomoto, T., Miki, T. and Yamaguchi, N. (2001). Alternative splicing isoforms of hippostasin (PRSS20/KLK11) in prostate cancer cell lines. Prostate, in press.
    • (2001) Prostate
    • Nakamura, T.1    Mitsui, S.2    Okui, A.3    Kominami, K.4    Nomoto, T.5    Miki, T.6    Yamaguchi, N.7
  • 75
    • 0033049658 scopus 로고    scopus 로고
    • Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression
    • Nelson, R. S., Gan, L., Ferguson, C., Moss, P., Gelinas, R., Hood, L., and Wang, K. (1999). Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression. Proc. Natl. Acad. Sci. USA 96, 3114-3119.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3114-3119
    • Nelson, R.S.1    Gan, L.2    Ferguson, C.3    Moss, P.4    Gelinas, R.5    Hood, L.6    Wang, K.7
  • 76
    • 0034530660 scopus 로고    scopus 로고
    • An alternatively spliced variant of KLK4 expressed in prostatic tissue
    • Obiezu, C. V. and Diamandis, E. P. (2000). An alternatively spliced variant of KLK4 expressed in prostatic tissue. Clin. Biochem. 33, 599-600.
    • (2000) Clin. Biochem , vol.33 , pp. 599-600
    • Obiezu, C.V.1    Diamandis, E.P.2
  • 78
    • 0031059178 scopus 로고    scopus 로고
    • Identification of a positive regulatory element responsible for tissue-specific expression of prostate-specific antigen
    • Pang, S., Dannull, J., Kaboo, R., Xie, Y., Tso, C. L., Michel, K., deKernion, J. B. and Belldegrun, A. S. (1997). Identification of a positive regulatory element responsible for tissue-specific expression of prostate-specific antigen. Cancer Res. 57, 495-499.
    • (1997) Cancer Res , vol.57 , pp. 495-499
    • Pang, S.1    Dannull, J.2    Kaboo, R.3    Xie, Y.4    Tso, C.L.5    Michel, K.6    deKernion, J.B.7    Belldegrun, A.S.8
  • 84
    • 0026034104 scopus 로고
    • Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species
    • Riegman, P. H., Vlietstra, R. J., van der Korput, H. A., Romijn, J. C. and Trapman, J. (1991a). Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species. Mol. Cell Endocrinol. 76, 181-190.
    • (1991) Mol. Cell Endocrinol , vol.76 , pp. 181-190
    • Riegman, P.H.1    Vlietstra, R.J.2    van der Korput, H.A.3    Romijn, J.C.4    Trapman, J.5
  • 85
    • 0026396005 scopus 로고
    • The promoter of the prostate-specific antigen gene contains a functional androgen responsive element
    • Riegman, P. H., Vlietstra, R. J., van der Korput, J. A., Brinkmann, A. O. and Trapman, J. (1991b). The promoter of the prostate-specific antigen gene contains a functional androgen responsive element. Mol. Endocrinol. 5, 1921-1930.
    • (1991) Mol. Endocrinol , vol.5 , pp. 1921-1930
    • Riegman, P.H.1    Vlietstra, R.J.2    van der Korput, J.A.3    Brinkmann, A.O.4    Trapman, J.5
  • 86
    • 0031665794 scopus 로고    scopus 로고
    • Human kallikrein 2 (hK2) and prostate-specific antigen (PSA): Two closely related, but distinct, kallikreins in the prostate
    • Rittenhouse, H. G., Finlay, J. A., Mikolajczyk, S. D. and Partin, A. W. (1998). Human kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate. Crit. Rev. Clin. Lab. Sci. 35, 275-368.
    • (1998) Crit. Rev. Clin. Lab. Sci , vol.35 , pp. 275-368
    • Rittenhouse, H.G.1    Finlay, J.A.2    Mikolajczyk, S.D.3    Partin, A.W.4
  • 87
    • 0030949438 scopus 로고    scopus 로고
    • Characterization of prostate-specific antigen proteolytic activity on its major physiological substrate, the sperm motility inhibitor precursor/semenogelin I
    • Robert, M., Gibbs, B. F., Jacobson, E. and Gagnon, C. (1997). Characterization of prostate-specific antigen proteolytic activity on its major physiological substrate, the sperm motility inhibitor precursor/semenogelin I. Biochemistry 36, 3811-3819.
    • (1997) Biochemistry , vol.36 , pp. 3811-3819
    • Robert, M.1    Gibbs, B.F.2    Jacobson, E.3    Gagnon, C.4
  • 88
    • 0018593041 scopus 로고
    • Kallikreins (kininogenases) - A group of serine proteases with bioregulatory actions
    • Schachter, M. (1979). Kallikreins (kininogenases) - a group of serine proteases with bioregulatory actions. Pharmacol. Rev. 31, 1-17.
    • (1979) Pharmacol. Rev , vol.31 , pp. 1-17
    • Schachter, M.1
  • 89
    • 0023553411 scopus 로고
    • Primary structure of a human glandular kallikrein gene
    • Schedlich, L. J., Bennetts, B. H. and Morris, B. J. (1987). Primary structure of a human glandular kallikrein gene. DNA 6, 429-437.
    • (1987) DNA , vol.6 , pp. 429-437
    • Schedlich, L.J.1    Bennetts, B.H.2    Morris, B.J.3
  • 90
    • 0037597389 scopus 로고    scopus 로고
    • Structure-function relationship in protein families
    • T. M. Devlin, ed. (New York, USA: Wiley-Liss, Inc.) 1-2-116
    • Schultz, R. M. and Liebman, M. N. (1997). Structure-function relationship in protein families. In: Textbook of Biochemistry with Clinical Correlations, T. M. Devlin, ed. (New York, USA: Wiley-Liss, Inc.), pp. 1-2-116.
    • (1997) Textbook of Biochemistry With Clinical Correlations
    • Schultz, R.M.1    Liebman, M.N.2
  • 92
    • 0003989132 scopus 로고
    • Human physiology. An integrated aproach
    • (New Jersy, USA: Prentice Hall)
    • Silverthorn, D. U. (1995). Human physiology. An integrated aproach (New Jersy, USA: Prentice Hall).
    • (1995)
    • Silverthorn, D.U.1
  • 93
    • 0034671481 scopus 로고    scopus 로고
    • Detection of metastatic prostate cancer using a splice variant-specific reverse transcriptase-polymerase chain reaction assay for human glandular kallikrein
    • Slawin, K. M., Shariat, S. F., Nguyen, C., Leventis, A. K., Song, W., Kattan, M. W., Young, C. Y., Tindall, D. J. and Wheeler, T. M. (2000). Detection of metastatic prostate cancer using a splice variant-specific reverse transcriptase-polymerase chain reaction assay for human glandular kallikrein. Cancer Res. 60, 7142-7148.
    • (2000) Cancer Res , vol.60 , pp. 7142-7148
    • Slawin, K.M.1    Shariat, S.F.2    Nguyen, C.3    Leventis, A.K.4    Song, W.5    Kattan, M.W.6    Young, C.Y.7    Tindall, D.J.8    Wheeler, T.M.9
  • 94
    • 0011128234 scopus 로고    scopus 로고
    • Starum corneum chymotryptic enzyme
    • A. J. Barrett, and J. F. Woessner, eds. (London, UK: Academic Press) pp
    • Smyth, M. J. (1998). Starum corneum chymotryptic enzyme. In Handbook of Proteolytic Enzymes, A. J. Barrett, and J. F. Woessner, eds. (London, UK: Academic Press), pp. 87-89.
    • (1998) Handbook of Proteolytic Enzymes , pp. 87-89
    • Smyth, M.J.1
  • 95
    • 0035398526 scopus 로고    scopus 로고
    • A genomic perspective on human proteases as drug targets
    • Southan, C. (2001). A genomic perspective on human proteases as drug targets. Drug Discov. Today 6, 681-688.
    • (2001) Drug Discov. Today , vol.6 , pp. 681-688
    • Southan, C.1
  • 96
    • 0033730301 scopus 로고    scopus 로고
    • Molecular forms of prostate-specific antigen and human kallikrein 2 as promising tools for early diagnosis of prostate cancer
    • Stephan, C., Jung, K., Lein, M., Sinha, P., Schnorr, D. and Loening, S. A. (2000). Molecular forms of prostate-specific antigen and human kallikrein 2 as promising tools for early diagnosis of prostate cancer. Cancer Epidemiol. Biomarkers Prev. 9, 1133-1147.
    • (2000) Cancer Epidemiol. Biomarkers Prev , vol.9 , pp. 1133-1147
    • Stephan, C.1    Jung, K.2    Lein, M.3    Sinha, P.4    Schnorr, D.5    Loening, S.A.6
  • 97
    • 0033551763 scopus 로고    scopus 로고
    • Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4
    • Stephenson, S. A., Verity, K., Ashworth, L. K. and Clements, J. A. (1999). Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4. J. Biol. Chem. 274, 23210-23214.
    • (1999) J. Biol. Chem , vol.274 , pp. 23210-23214
    • Stephenson, S.A.1    Verity, K.2    Ashworth, L.K.3    Clements, J.A.4
  • 100
    • 0030779820 scopus 로고    scopus 로고
    • Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein
    • Takayama, T. K., Fujikawa, K. and Davie, E. W. (1997). Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein. J. Biol. Chem. 272, 21582-21588.
    • (1997) J. Biol. Chem , vol.272 , pp. 21582-21588
    • Takayama, T.K.1    Fujikawa, K.2    Davie, E.W.3
  • 101
    • 0035852815 scopus 로고    scopus 로고
    • Activation of prostate-specific antigen precursor (pro-PSA) by prostin, a novel human prostatic serine protease identified by degenerate PCR
    • Takayama, T. K., Carter, C. A. and Deng, T. (2001 a). Activation of prostate-specific antigen precursor (pro-PSA) by prostin, a novel human prostatic serine protease identified by degenerate PCR. Biochemistry 40, 1679-1687.
    • (2001) Biochemistry , vol.40 , pp. 1679-1687
    • Takayama, T.K.1    Carter, C.A.2    Deng, T.3
  • 102
    • 0035909802 scopus 로고    scopus 로고
    • Characterization of hK4 (prostase), a prostate-specific serine protease: Activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase
    • Takayama, T. K., McMullen, B. A., Nelson, P. S., Matsumura, M. and Fujikawa, K. (2001b). Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase. Biochemistry 40, 15341-15348.
    • (2001) Biochemistry , vol.40 , pp. 15341-15348
    • Takayama, T.K.1    McMullen, B.A.2    Nelson, P.S.3    Matsumura, M.4    Fujikawa, K.5
  • 103
    • 0033966958 scopus 로고    scopus 로고
    • A novel form of prostate-specific antigen transcript produced by alternative splicing
    • Tanaka, T., Isono, T., Yoshiki, T., Yuasa, T. and Okada, Y. (2000). A novel form of prostate-specific antigen transcript produced by alternative splicing. Cancer Res. 60, 56-59.
    • (2000) Cancer Res , vol.60 , pp. 56-59
    • Tanaka, T.1    Isono, T.2    Yoshiki, T.3    Yuasa, T.4    Okada, Y.5
  • 104
    • 0033571558 scopus 로고    scopus 로고
    • The stratum corneum chymotryptic enzyme that mediates shedding and desquamation of skin cells is highly overexpressed in ovarian tumor cells
    • Tanimoto, H., Underwood, L. J., Shigemasa, K., Yan Yan, M. S., Clarke, J., Parmley, T. H. and O'Brien, T. J. (1999). The stratum corneum chymotryptic enzyme that mediates shedding and desquamation of skin cells is highly overexpressed in ovarian tumor cells. Cancer 86, 2074-2082.
    • (1999) Cancer , vol.86 , pp. 2074-2082
    • Tanimoto, H.1    Underwood, L.J.2    Shigemasa, K.3    Yan Yan, M.S.4    Clarke, J.5    Parmley, T.H.6    O'Brien, T.J.7
  • 105
    • 0031079544 scopus 로고    scopus 로고
    • Androgen-regulated gene expression in prostate cancer
    • Trapman, J. and Cleutjens, K. B. (1997). Androgen-regulated gene expression in prostate cancer. Semin. Cancer Biol. 8, 29-36.
    • (1997) Semin. Cancer Biol , vol.8 , pp. 29-36
    • Trapman, J.1    Cleutjens, K.B.2
  • 106
    • 0033198458 scopus 로고    scopus 로고
    • Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma
    • Underwood, L. J., Tanimoto, H., Wang, Y., Shigemasa, K., Parmley, T. H. and O'Brien, T. J. (1999). Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma. Cancer Res. 59, 4435-4439.
    • (1999) Cancer Res , vol.59 , pp. 4435-4439
    • Underwood, L.J.1    Tanimoto, H.2    Wang, Y.3    Shigemasa, K.4    Parmley, T.H.5    O'Brien, T.J.6
  • 107
    • 0022998481 scopus 로고
    • Mouse glandular kallikrein genes. Identification, structure, and expression of the renal kallikrein gene
    • van Leeuwen, B. H., Evans, B. A., Tregear, G. W. and Richards, R. I. (1986). Mouse glandular kallikrein genes. Identification, structure, and expression of the renal kallikrein gene. J. Biol. Chem. 261, 5529-5535.
    • (1986) J. Biol. Chem , vol.261 , pp. 5529-5535
    • van Leeuwen, B.H.1    Evans, B.A.2    Tregear, G.W.3    Richards, R.I.4
  • 110
    • 0032525843 scopus 로고    scopus 로고
    • Sequence analysis and expression of human neuropsin cDNA and gene
    • Yoshida, S., Taniguchi, M., Hirata, A. and Shiosaka, S. (1998a). Sequence analysis and expression of human neuropsin cDNA and gene. Gene 213, 9-16.
    • (1998) Gene , vol.213 , pp. 9-16
    • Yoshida, S.1    Taniguchi, M.2    Hirata, A.3    Shiosaka, S.4
  • 112
    • 0033621445 scopus 로고    scopus 로고
    • The new kallikrein-like gene, KLK-L2. Molecular characterization, mapping, tissue expression, and hormonal regulation
    • Yousef, G. M. and Diamandis, E. P. (1999). The new kallikrein-like gene, KLK-L2. Molecular characterization, mapping, tissue expression, and hormonal regulation. J. Biol. Chem. 274, 37511-37516.
    • (1999) J. Biol. Chem , vol.274 , pp. 37511-37516
    • Yousef, G.M.1    Diamandis, E.P.2
  • 113
    • 0034654654 scopus 로고    scopus 로고
    • The expanded human kallikrein gene family: Locus characterization and molecular cloning of a new member, KLK-L3 (KLK9)
    • Yousef, G. M. and Diamandis, E. P. (2000). The expanded human kallikrein gene family: locus characterization and molecular cloning of a new member, KLK-L3 (KLK9). Genomics 65, 184-194.
    • (2000) Genomics , vol.65 , pp. 184-194
    • Yousef, G.M.1    Diamandis, E.P.2
  • 114
    • 0035018273 scopus 로고    scopus 로고
    • The new human tissue kallikrein gene family: Structure, function, and association to disease
    • Yousef, G. M. and Diamandis, E. P. (2001). The new human tissue kallikrein gene family: structure, function, and association to disease. Endocr. Rev. 22, 184-204.
    • (2001) Endocr. Rev , vol.22 , pp. 184-204
    • Yousef, G.M.1    Diamandis, E.P.2
  • 115
    • 0003286064 scopus 로고    scopus 로고
    • Human kallikreins: Common structural features, sequence analysis and evolution
    • in press
    • Yousef, G. M. and Diamandis, E. P. (2002). Human kallikreins: common structural features, sequence analysis and evolution. Curr. Genomics, in press.
    • (2002) Curr. Genomics
    • Yousef, G.M.1    Diamandis, E.P.2
  • 116
    • 0033452558 scopus 로고    scopus 로고
    • Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4
    • Yousef, G. M., Luo, L. Y., and Diamandis, E.P. (1999a). Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4. Anticancer Res. 19, 2843-2852.
    • (1999) Anticancer Res , vol.19 , pp. 2843-2852
    • Yousef, G.M.1    Luo, L.Y.2    Diamandis, E.P.3
  • 117
    • 0033385499 scopus 로고    scopus 로고
    • Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease
    • Yousef, G. M., Luo, L. Y., Scherer, S. W., Sotiropoulou, G. and Diamandis, E. P. (1999b). Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease. Genomics 62, 251-259.
    • (1999) Genomics , vol.62 , pp. 251-259
    • Yousef, G.M.1    Luo, L.Y.2    Scherer, S.W.3    Sotiropoulou, G.4    Diamandis, E.P.5
  • 118
    • 0033198389 scopus 로고    scopus 로고
    • Prostase/KLK-L1 is a new member of the human kallikrein gene family, is expressed in prostate and breast tissues, and is hormonally regulated
    • Yousef, G. M., Obiezu, C. V., Luo, L. Y., Black, M. H. and Diamandis, E. P. (1999c). Prostase/KLK-L1 is a new member of the human kallikrein gene family, is expressed in prostate and breast tissues, and is hormonally regulated. Cancer Res. 59, 4252-4256.
    • (1999) Cancer Res , vol.59 , pp. 4252-4256
    • Yousef, G.M.1    Obiezu, C.V.2    Luo, L.Y.3    Black, M.H.4    Diamandis, E.P.5
  • 119
    • 0034003086 scopus 로고    scopus 로고
    • Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family
    • Yousef, G. M., Scorilas A., and Diamandis E. P. (2000a). Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family. Genomics 63, 88-96.
    • (2000) Genomics , vol.63 , pp. 88-96
    • Yousef, G.M.1    Scorilas, A.2    Diamandis, E.P.3
  • 120
    • 0034697143 scopus 로고    scopus 로고
    • Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues
    • Yousef, G. M., Chang, A. and Diamandis, E. P. (2000b). Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues. J. Biol. Chem. 275, 11891-11898.
    • (2000) J. Biol. Chem , vol.275 , pp. 11891-11898
    • Yousef, G.M.1    Chang, A.2    Diamandis, E.P.3
  • 121
    • 0034675353 scopus 로고    scopus 로고
    • Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4
    • Yousef, G. M., Chang, A., Scorilas, A. and Diamandis, E. P. (2000c). Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4. Biochem. Biophys. Res. Commun. 276, 125-133.
    • (2000) Biochem. Biophys. Res. Commun , vol.276 , pp. 125-133
    • Yousef, G.M.1    Chang, A.2    Scorilas, A.3    Diamandis, E.P.4
  • 122
    • 0034331157 scopus 로고    scopus 로고
    • KLK12 is a novel serine protease and a new member of the human kallikrein gene family-differential expression in breast cancer
    • Yousef, G. M., Magklara, A. and Diamandis, E. P. (2000d). KLK12 is a novel serine protease and a new member of the human kallikrein gene family-differential expression in breast cancer. Genomics 69, 331-341.
    • (2000) Genomics , vol.69 , pp. 331-341
    • Yousef, G.M.1    Magklara, A.2    Diamandis, E.P.3
  • 123
    • 0034003086 scopus 로고    scopus 로고
    • Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family
    • Yousef, G. M., Scorilas, A. and Diamandis, E. P. (2000e). Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family. Genomics 63, 88-96.
    • (2000) Genomics , vol.63 , pp. 88-96
    • Yousef, G.M.1    Scorilas, A.2    Diamandis, E.P.3
  • 124
    • 0034702897 scopus 로고    scopus 로고
    • The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family - Genomic characterization, mapping, tissue expression and hormonal regulation
    • Yousef, G. M., Scorilas, A., Magklara, A., Soosaipillai, A. and Diamandis, E. p. (2000f). The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family - genomic characterization, mapping, tissue expression and hormonal regulation. Gene 254, 119-128.
    • (2000) Gene , vol.254 , pp. 119-128
    • Yousef, G.M.1    Scorilas, A.2    Magklara, A.3    Soosaipillai, A.4    Diamandis, E.P.5
  • 126
    • 0035870283 scopus 로고    scopus 로고
    • Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies
    • Yousef, G. M., Magklara, A., Chang, A., Jung, K., Katsaros, D. and Diamandis, E. P. (2001b). Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies. Cancer Res. 61, 3425-3431.
    • (2001) Cancer Res , vol.61 , pp. 3425-3431
    • Yousef, G.M.1    Magklara, A.2    Chang, A.3    Jung, K.4    Katsaros, D.5    Diamandis, E.P.6
  • 127
    • 0035808428 scopus 로고    scopus 로고
    • Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer
    • Yousef, G. M., Scorilas, A., Jung, K., Ashworth, L. K. and Diamandis, E. P. (2001c). Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer. J. Biol. Chem. 276, 53-61.
    • (2001) J. Biol. Chem , vol.276 , pp. 53-61
    • Yousef, G.M.1    Scorilas, A.2    Jung, K.3    Ashworth, L.K.4    Diamandis, E.P.5
  • 128
    • 0036774212 scopus 로고    scopus 로고
    • Differetial expression of kallikrein gene 5 (KLK5) in cancerous and normal testicular tissues
    • in press
    • Yousef, G. M., Obiezu, C., Jung, K., Stephan, C., Scorilas, A. and Diamandis, E. P. (2002a). Differetial expression of kallikrein gene 5 (KLK5) in cancerous and normal testicular tissues. Urology, in press.
    • (2002) Urology
    • Yousef, G.M.1    Obiezu, C.2    Jung, K.3    Stephan, C.4    Scorilas, A.5    Diamandis, E.P.6
  • 131
    • 0033119603 scopus 로고    scopus 로고
    • Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy
    • Yu, D. C., Sakamoto, G. T. and Henderson, D. R. (1999). Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy. Cancer Res. 59, 1498-1504.
    • (1999) Cancer Res , vol.59 , pp. 1498-1504
    • Yu, D.C.1    Sakamoto, G.T.2    Henderson, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.