An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter

Molecular Endocrinology

Volumn 11, Issue 2, 1997, Pages 148-161

  Cleutjens, Kitty B J M ^a   Van Der Korput, Hetty A G M ^a   Van Eekelen, Conny C E M ^a   Van Rooij, Henri C J ^a   Faber, Peter W ^a,b   Trapman, Jan ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; DEOXYRIBONUCLEASE I; PROSTATE SPECIFIC ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; ENHANCER REGION; GENE EXPRESSION REGULATION; GENE MAPPING; HORMONAL REGULATION; HORMONE RESPONSE; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; TRANSCRIPTION INITIATION;

EID: 0031017102     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.2.9883     Document Type: Article

References (35)

1. Catalona WJ, Smith DS, Ratcliff TL, Dodds KM, Coplen DE, Yuan JJ, Petros JA, Andriole GL 1991 Measurement of prostate-specific antigen in serum as a screening test for prostate cancer. N Engl J Med 324:1156-1161
2. Oesterling JE 1991 Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate. J Urol 145:907-923
3. Riegman PHJ, Vlietstra RJ, Korput JAGM van der, Romijn JC, Trapman J 1989 Characterization of the prostate specific antigen gene: a novel kallikrein-like gene. Biochem Biophys Res Commun 159:95-102
4. Lundwall A 1989 Characterization of the gene for prostate specific antigen, a human glandular kallikrein. Biochem Biophys Res Commun 161:1151-1159
5. Schedlich LJ, Bennets BH, Morris BJ 1987 Primary structure of a human glandular kallikrein gene. DNA 6:429-437
6. Evans BA, Zhang XY, Close JA, Tregear GW, Kitamura N, Nakanishi S, Callen DF, Baker E, Hyland VJ, Sutherland GR, Richards RI 1988 Structure and chromosomal localization of the human renal kallikrein gene. Biochemistry 27:3124-3129
7. Riegman PHJ, Vlietstra RJ, Suurmeijer L, Cleutjens CBJM, Trapman J 1992 Characterization of the human kallikrein locus. Genomics 14:6-11
8. Riegman PHJ, Vlietstra RJ, Korput JAGM van der, Romijn JC, Trapman J 1991 Identification and androgen regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species. Mol Cell Endocrinol 76:181-190
9. Henntu P, Liao S, Vikho P 1992 Androgens upregulate the human prostate specific antigen messenger ribonucleic acid, but down-regulate the prostatic phosphatase mRNA in LNCaP cells. Endocrinology 130:766-772
10. Young CYF, Andrews PE, Montgomery BT, Tindall DJ 1992 Tissue specific and hormonal regulation of human prostate-specific glandular kallikrein. Biochemistry 31:818-824
11. Riegman PHJ, Vlietstra RJ, Korput JAGM van der, Brinkmann AO, Trapman J 1991 The promoter of the prostate-specific antigen gene contains a functional androgen responsive element. Mol Endocrinol 5:1921-1930
12. Wolf DA, Schulz P, Fittler F 1992 Transcriptional regulation of prostate kallikrein-like genes by androgen. Mol Endocrinol 6:753-762
13. Cleutjens KBJM, van Eekelen CCEM, van der Korput HAGM, Brinkmann AO, Trapman J 1996 Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter. J Biol Chem 271:6379-6388
14. Wood WG 1996 The complexities of β-globin gene regulation. Trends Genet 12:204-206
15. Nitsch D, Boshart M, Schütz G 1993 Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements. Proc Natl Acad Sci USA 90:5479-5483
16. Grange T, Roux J, Rigaud G, Pictet R 1989 Two remote glucocorticoid responsive units interact cooperatively to promote glucocorticoid induction of rat tyrosine animo-transferase gene expression. Nucleic Acids Res 17:8695-8709
17. Cleutjens CBJM, van der Korput JAGM, van Eekelen CCEM, van Rooij HCJ, Faber PW, Trapman J 1995 Identification of three regions involved in androgen regulated activity of the prostate-specific antigen promoter in LN-CaP prostate cells. Urol Res 23:269
18. Schuur ER, Henderson GA, Kmetec LA, Miller JD, Lamparski HG, Henderson DR 1996 Prostate-specific antigen expression is regulated by an upstream enhancer. J Biol Chem 271:7043-7051
19. Roche PJ, Hoare SA, Parker MG 1992 A consensus DNA-binding site for the androgen receptor. Mol Endocrinol 6:2229-2235
20. Tjian R, Maniatis T 1994 Transcriptional activation: a complex puzzle with few easy pieces. Cell 77:5-8
21. Koleske AJ, Young RA 1995 The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem Sci 20:113-116
22. Sassi H, Fromont-Racine M, Grange T, Pictet R 1995 Tissue specificity of a glucocorticoid-dependent enhancer in transgenic mice. Proc Natl Acad Sci USA 92:7197-7201
23. Rennie PS, Bruchovsky N, Leco KJ, Sheppard PC, McQueen SA, Cheng H, Snoek R, Hamel A, Bock ME, MacDonald BS, Nickel BE, Chang C, Liao S, Cattini PA, Matusik RJ 1993 Characterization of two cis-acting DNA elements involved in the androgen regulation of the pro-basin gene. Mol Endocrinol 7:23-36
24. Kasper S, Rennie PS, Bruchovsky N, Sheppard PC, Cheng H, Lin L, Shiu RPC, Snoek R, Matusik RJ 1994 Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the pro-basin gene. J Biol Chem 269:31763-31769
25. Monne M, Croce CM, Yu H, Diamandis EP 1994 Molecular characterization of prostate-specific antigen messenger RNA expressed in breast tumors. Cancer Res 54:6344-6347
26. Giai M, Yu H, Roagna R, Ponzone R, Katsaros D, Levesque MA, Diamandis EP 1995 Prostate-specific antigen in serum of women with breast cancer. Br J Cancer 72:728-731
27. Horoszewicz JS, Leong SS, Kawinski E, Karr J, Rosenthal H, Chu TM, Mirand EA, Murphy GP 1983 LNCaP model of human prostatic carcinoma. Cancer Res 43:1809-1818
28. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
29. Brinkmann AO, Faber PW, Rooij HCJ van, Kuiper GGJM, Ris C, Klaassen P, Korput JAGM van der, Voorhorst MM, Laar JH van, Mulder E, Trapman J 1989 The human androgen receptor: domain structure, genomic organization and regulation of expression. J Steroid Biochem 34:307-310
30. De Vos P, Claessens F, Winderickx J, Van Dijck P, Celis L, Peeters B, Rombauts W, Heyns W, Verhoeven G 1991 Interaction of androgen response elements with the DNA-binding domain of the rat androgen receptor expressed in Escherichia coli. J Biol Chem 266:3439-3443
31. de Ruiter PE, Teuwen R, Trapman J, Dijkma R, Brinkmann AO 1995 Synergism between androgens and protein kinase-C on androgen-regulated gene expression. Mol Cell Endocrinol 110:R1-R6
32. Higuchi R, Krummel B, Saiki RK 1988 A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res 16:7351-7367
33. Chen C, Okyama H 1987 High efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7:2745-2752
34. Lemaigre FP, Courtois SJ, Lafontaine DA, Rousseau GG 1989 Evidence that the upstream stimulatory factor and the SpI transcription factor bind in vitro to the promoter of the human-growth-hormone gene. Eur J Biochem 181:555-561
35. Maxam AM, Gilbert W 1980 Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol 65:499-560