A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate

Biochemical and Biophysical Research Communications

Volumn 272, Issue 1, 2000, Pages 205-211

  Mitsui, Shinichi ^a   Yamada, Tatsuo ^b   Okui, Akira ^c   Kominami, Katsuya ^c   Uemura, Hidetoshi ^c   Yamaguchi, Nozomi ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

^c Fuso Pharmaceutical Industries   (Japan)

Author keywords

Alternative splicing; Brain; Hippocampus; Prostate; Serine protease

Indexed keywords

BRAIN ENZYME; COMPLEMENTARY DNA; HIPPOSTASIN; ISOENZYME; KALLIKREIN; SERINE PROTEINASE; SIGNAL PEPTIDE; TRYPSINOGEN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; KERATINOCYTE; LUNG; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE; PYRAMIDAL NERVE CELL; SEQUENCE HOMOLOGY;

ANIMALIA;

EID: 0034720485     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2761     Document Type: Article

References (21)

1. Yoshida, S., Taniguchi, M., Suemoto, T., Oka, T., He, X.-P., and Shiosaka, S. (1998) cDNA cloning and expression of a novel serine protease, TLSP. Biochim. Biophys. Acta 1339, 225-228.
2. Turgeon, V. L., and Houenou, L. J. (1997) The role of thrombin-like (serine) proteases in the development, plasticity and pathology of the nervous system. Brain Res. Rev. 25, 85-95.
3. Yoshida, S., and Shiosaka, S. (1999) Plasticity-related serine proteases in the brain. Int. J. Mol. Med. 3, 405-409.
4. Yamamura, Y., Yamashiro, K., Tsuraoka, N., Nakazato, H., Tsujimura, A., and Yamaguchi, N. (1997) Molecular cloning of a novel brain-specific serine protease with a kringle-like structure and three scavenger receptor cysteine-rich motifs. Biochem. Biophys. Res. Commun. 239, 386-392.
5. Iijima, N., Tanaka, M., Mitsui, S., Yamamura, Y., Yamaguchi, N., and Ibata, Y. (1999) Expression of a serine protease (motopsin PRSS12) mRNA in the mouse brain: In situ hybridization histochemical study. Mol. Brain Res. 66, 141-149.
6. Little, S. P., Dixon, E. P., Norris, F., Buckley, W., Becker, G. W., Johnson, M., Dobbins, J. R., Wyrich, T., Miller, J. R., MacKellar, W., Hepburn, D., Corvalan, J., McClure, D., Liu, X., Stephenson, D., Clemens, J., and Johnstone, E. M. (1997) Zyme, a novel and potentially amyloidgenic enzyme cDNA isolated from Alzheimer's disease brain. J. Biol. Chem. 272, 25135-25142.
7. Yamashiro, K., Tsuruoka, N., Kodama, S., Tsujimoto, M., Yamamura, Y., Tanaka, T., Nakazato, H., and Yamaguchi, N. (1997) Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain. Biochim. Biophys. Acta 1350, 11-14.
8. Mitsui, S., Tsuruoka, N., Yamashiro, K., Nakazato, H., and Yamaguchi N. (1999) A novel form of human neuropsin, a brain-related serine protease, is generated by alternative splicing and is expressed preferentially in human adult brain. Eur. J. Biochem. 260, 627-634.
9. Poorafshar, M., and Hellman, L. (1999) Cloning and structurral analysis of leydin, a novel human serine protease expressed by the Leydig cells of the testis. Eur. J. Biochem. 261, 244-250.
10. Suemoto, T., Taniguchi, M., Shiosaka, S., and Yoshida, S. (1999) cDNA cloning and expression of a novel serine protease, TLSP. Mol. Brain Res. 70, 273-281.
11. Sambrook, J., Fritch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory Press, New York.
12. Chen, Z.-L., Yoshida, S., Kato, K., Momota, Y., Suzuki, J., Tanaka, T., Ito J., Nishino, H., Aimoto, S., Kiyama, H., and Shiosaka, S. (1995) Expression and activity-dependent changes of a novel limbic-serine protease gene in the hippocampus. J. Neurosci. 15, 5088-5097.
13. Qian, Z., Gilbert, M. E., Colicos, M. A., Kandel, E. R., and Kuhl, D. (1993) Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361, 453-457.
14. Huang, Y.-Y., Bach, M. E., Lipp, H.-P., Zhuo, M., Wolfer, D. P., Hawkins, R. D., Schoonjans, L., Kandel, E. R., Godfraind, J.-M., Mulligan, R., Collen, D., and Carmeliet, P. (1996) Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc. Natl. Acad. Sci. USA 93, 8699-8704.
15. Hoffman, K. B., Martinez, J., and Lynch, G. (1998) Proteolysis of cell adhesion molecules by serine protease: A role in long term ptentiation? Brain Res. 811, 29-33.
16. Mikolajczyk, S. D., Millar, L. S., Kumar, A., and Saedi, M. S. (1998) Human grandular kallikrein, hK2, shows arginin-restricted specificity and forms complex with plasma prostate inhibitor. Prostate 34, 44-50.
17. Charlesworth, M. C., Young, C. Y., Miller, V. M., and Tindall, D. J. (1999) Kininogenase activity of prostate-derived human glandular kallikrein (hK2) purified from seminal fluid. J. Androl. 20, 220-229.
18. Takayama, T. K., Fujikawa, K., and Davie, E. W. (1997) Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein. J. Biol. Chem. 34, 21582-21588.
19. Matsumoto, A., Itoh, K., and Matsumoto, R. (2000) A novel carboxypeptidase B that processes native beta-amyloid precursor protein is present in human hippocampus. Eur. J. Neurosci. 12, 227-238.
20. Hershberger, R. J., Gershenfeld, H. K., Weissman, I. L., and Su, L. (1992) Genomic organization of the mouse granzyme A gene. Two mRNAs encode the same mature granzyme A with different leader peptides. J. Biol. Chem. 267, 25488-25493.
21. Mehtani, S., Gong, Q., Panella, J., Subbiah, S., Peffley D. M., and Frankfater, A. (1998) In vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells. J. Biol. Chem. 273, 13236-13244.