Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies

Cancer Research

Volumn 61, Issue 8, 2001, Pages 3425-3431

  Yousef, George M ^a,b   Magklara, Angeliki ^a,b   Chang, Albert ^a,b   Jung, Klaus ^c   Katsaros, Dionyssios ^d   Diamandis, Eleftherios P ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

KALLIKREIN;

ARTICLE; BREAST CANCER; CARCINOGENESIS; CHROMOSOME 19Q; EXON; GENE CONTROL; GENE MAPPING; GENE STRUCTURE; HUMAN; HUMAN CELL; INTRON; MOLECULAR CLONING; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; OVARY CANCER; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN PROCESSING; TESTIS CANCER;

AMINO ACID SEQUENCE; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 19; CLONING, MOLECULAR; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KALLIKREINS; MALE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NEOPLASMS; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035870283     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Lessons learned, promises kept: A biologist's eye view of the Genome Project
2. The molecular biology of the kallikreins and their roles in inflammation
3. Structure and chromosomal localization of the human renal kallikrein gene
4. Primary structure of a human glandular kallikrein gene
5. Characterization of the prostate-specific antigen gene: A novel human kallikrein-like gene
6. The new human kallikrein gene family: Implications in carcinogenesis
7. Tissue kallikreins: Structure, regulation, and participation in mammalian physiology and disease
8. Prostate-specific antigen: Its usefulness in clinical medicine
9. New ultrasensitive assays facilitate studies on the role of human glandular kallikrein (hK2) as a marker for prostatic disease
10. The role for NES1 serine protease as a novel tumor suppressor
11. A novel protease homolog differentially expressed in breast and ovarian cancer
12. Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma
13. The stratum corneum chymotryptic enzyme that mediates shedding and desquamation of skin cells is highly overexpressed in ovarian tumor cells
14. Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4
15. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
16. The I.M.A.G.E. Consortium: An integrated molecular analysis of genomes and their expression
17. Factors influencing the ratio of free to total prostate-specific antigen in serum
18. Prostase/KLK-L1 is a new member of the human kallikrein gene family, is expressed in prostate and breast tissues, and is hormonally regulated
19. The new kallikrein-like gene, KLK-L2. Molecular characterization, mapping, tissue expression, and hormonal regulation
20. An analysis of vertebrate mRNA sequences: Intimations of translational control
21. Quantification analysis of 5′-splice signal sequences in mRNA precursors. Mutations in 5′-splice signal sequence of human β-globin gene and β-thalassemia
22. Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease
23. Sequence analysis and expression of human neuropsin cDNA and gene
24. Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression
25. Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain
26. Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain
27. The origin and evolution of protein superfamilies
28. Two types of amino acid substitutions in protein evolution
29. Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression
30. The expanded human kallikrein gene family: Locus characterization and molecular cloning of a new member, KLK-L3 (KLK9)
31. Structure and evolution of the bovine prothrombin gene
32. Structural characterization and mapping of the normal epithelial cell-specific 1 gene
33. Antiangiogenic activity of prostate-specific antigen
34. Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues
35. Effects of oxidative stress on the expression of limbic-specific protease neuropsin and avoidance learning in mice
36. cDNA cloning and expression of a novel serine protease, TLSP