Tales from the crypt(ochromes)

Journal of Biological Rhythms

Volumn 17, Issue 2, 2002, Pages 110-120

  Van Gelder, Russell N ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blue light photoreception; Circadian rhythm; Cryptochrome; Nonvisual photoreception

Indexed keywords

CRYPTOCHROME; CRYPTOCHROME PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; EYE PROTEIN; FLAVOPROTEIN; G PROTEIN COUPLED RECEPTOR;

ARABIDOPSIS; CIRCADIAN RHYTHM; DROSOPHILA; HUMAN; NONHUMAN; PHOTOSTIMULATION; PHOTOTRANSDUCTION; PHYLOGENY; PLEIOTROPY; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; ANIMAL; CHEMISTRY; GENETICS; INSECT; PHOTORECEPTOR; PHYSIOLOGY; PLANT PHYSIOLOGY;

ARABIDOPSIS; HEXAPODA; MAMMALIA;

ANIMALS; CIRCADIAN RHYTHM; DROSOPHILA PROTEINS; EYE PROTEINS; FLAVOPROTEINS; HUMANS; INSECTS; PHOTORECEPTORS, INVERTEBRATE; PLANT PHYSIOLOGY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 0036546520     PISSN: 07487304     EISSN: None     Source Type: Journal    
DOI: 10.1177/074873002129002401     Document Type: Review

References (101)

1. Ahmad M and Cashmore AR (1993) HY4 gene of A. thaliana encodes a protein with characteristics of a blue-light photoreceptor. Nature 366:162-166.
2. Ahmad M and Cashmore AR (1997) The blue-light receptor cryptochrome 1 shows functional dependence on phytochrome A or phytochrome B in Arabidopsis thaliana. Plant J 11:421-427.
3. Ahmad M, Jarillo JA, and Cashmore AR (1998a) Chimeric proteins between cryl and cry2 Arabidopsis blue light photoreceptors indicate overlapping functions and varying protein stability. Plant Cell 10:197-207.
4. Ahmad M, Jarillo JA, Smirnova O, and Cashmore AR (1998b) The CRY1 blue light photoreceptor of Arabidopsis interacts with phytochrome A in vitro. Mol Cell 1:939-948.
5. Alabadi D, Oyama T, Yanovsky MJ, Harmon FG, Mas P, and Kay SA (2001) Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock. Science 293:880-883.
6. Balsalobre A, Damiola F, and Schibler U (1998) A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93:929-937.
7. Blackshaw S and Snyder SH (1999) Encephalopsin: A novel mammalian extraretinal opsin discretely localized in the brain. J Neurosci 19:3681-3690.
8. Briggs WR, Beck CF, Cashmore AR, Christie JM, Hughes J, Jarillo JA, Kagawa T, Kanegae H, Liscum E, Nagatani A, Okada K, Salomon M, Rudiger W, Sakai T, Takano M, Wada M, and Watson JC (2001) The phototropin family of photoreceptors. Plant Cell 13:993-997.
9. Briggs WR and Huala E (1999) Blue-light photoreceptors in higher plants. Annu Rev Cell Dev Biol 15:33-62.
10. Casal JJ (2000) Phytochromes, cryptochromes, phototropin: Photoreceptor interactions in plants. Photochem Photobiol 71:1-11.
11. Ceriani MF, Darlington TK, Staknis D, Mas P, Petti AA, Weitz CJ, and Kay SA (1999) Light-dependent sequestration of TIMELESS by CRYPTOCHROME. Science 285:553-556.
12. Darwin C (1881) The Power of Movement in Plants, Da Capo Press, New York.
13. Deisenhofer J (2000) DNA photolyases and cryptochromes. Mutat Res 460:143-149.
14. Devlin PF and Kay SA (1999) Cryptochromes - Bringing the blues to circadian rhythms. Trends Cell Biol 9:295-298.
15. Devlin PF and Kay SA (2000) Cryptochromes are required for phytochrome signaling to the circadian clock but not for rhythmicity. Plant Cell 12:2499-2510.
16. Ebihara S and Tsuji K (1980) Entrainment of the circadian activity rhythm to the light cycle: Effective light intensity for a zeitgeber in the retinal degenerate C3H mouse and the normal C57BL mouse. Physiol Behav 24:523-527.
17. Egan ES, Franklin TM, Hilderbrand-Chae MJ, McNeil GP, Roberts MA, Schroeder AJ, Zhang X, and Jackson FR (1999) An extraretinally expressed insect cryptochrome with similarity to the blue light photoreceptors of mammals and plants. J Neurosci 19:3665-3673.
18. Emery P, So WV, Kaneko M, Hall JC, and Rosbash M (1998) CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity. Cell 95:669-679.
19. Emery P, Stanewsky R, Hall JC, and Rosbash M (2000a) A unique circadian-rhythm photoreceptor. Nature 404: 456-457.
20. Emery P, Stanewsky R, Helfrich-Forster C, Emery-Le M, Hall JC, and Rosbash M (2000b) Drosophila CRY is a deep brain circadian photoreceptor. Neuron 26:493-504.
21. Ferguson TA, Mahendra SL, Hooper P, and Kaplan HJ (1992) The wavelength of light governing intraocular immune reactions. Invest Ophthalmol Vis Sci 33:1788-1795.
22. Foster RG, Provencio I, Hudson D, Fiske S, De Grip W, and Menaker M (1991) Circadian photoreception in the retinally degenerate mouse (rd/rd). J Comp Physiol A: Sensory Neural Behav Physiol 169:39-50.
23. Freedman MS, Lucas RJ, Soni B, von Schantz M, Munoz M, David-Gray Z, and Foster R (1999) Regulation of mammalian circadian behavior by non-rod, non-cone, ocular photoreceptors. Science 284:502-504.
24. Giebultowicz JM and Hege DM (1997) Circadian clock in malpighian tubules. Nature 386:664.
25. Gooley JJ, Lu J, Chou TC, Scammell TE, and Saper CB (2001) Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci 4:1165.
26. Gressel J (1979) Blue light photoreception. Photochem Photobiol 30:749-754.
27. Griffin EA Jr, Staknis D, and Weitz CJ (1999) Light-independent role of CRY1 and CRY2 in the mammalian circadian clock. Science 286:768-771.
28. Guo H, Yang H, Mockler TC, and Lin C (1998) Regulation of flowering time by Arabidopsis photoreceptors. Science 279:1360-1363.
29. Hall JC (2000) Cryptochromes: Sensory reception, transduction, and clock functions subserving circadian systems. Curr Opin Neurobiol 10:456-466.
30. Hao W and Fong HK (1996) Blue and ultraviolet light-absorbing opsin from the retinal pigment epithelium. Biochemistry 35:6251-6256.
31. Harmer SL, Hogenesch JB, Straume M, Chang HS, Han B, Zhu T, Wang X, Kreps JA, and Kay SA (2000) Orchestrated transcription of key pathways in Arabidopsis by the circadian clock. Science 290:2110-2113.
32. Hege DM, Stanewsky R, Hall JC, and Giebultowicz JM (1997) Rhythmic expression of a PER-reporter in the malpighian tubules of decapitated Drosophila: Evidence for a brain-independent circadian clock. J Biol Rhythms 12:300-308.
33. Helfrich-Forster C, Winter C, Hofbauer A, Hall JC, and Stanewsky R (2001) The circadian clock of fruit flies is blind after elimination of all known photoreceptors. Neuron 30:249-261.
34. Hsu DS, Zhao X, Zhao S, Kazantsev A, Wang RP, Todo T, Wei YF, and Sancar A (1996) Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins. Biochemistry 35:13871-13877.
35. Hunter-Ensor M, Ousley A, and Sehgal A (1996) Regulation of the Drosophila protein Timeless suggests a mechanism for resetting the circadian clock by light. Cell 84:677-685.
36. Ishikawa T, Matsumoto A, Kato T Jr, Togashi S, Ryo H, Ikenaga M, Todo T, Ueda R, and Tanimura T (1999) DCRY is a Drosophila photoreceptor protein implicated in light entrainment of circadian rhythm. Genes Cells 4:57-65.
37. Ivanchenko M, Stanewsky R, and Giebultowicz JM (2001) Circadian photoreception in Drosophila: Functions of cryptochrome in peripheral and central clocks. J Biol Rhythms 16:205-215.
38. Jarillo JA, Capel J, Tang RH, Yang HQ, Alonso JM, Ecker JR, and Cashmore AR (2001) An Arabidopsis circadian clock component interacts with both CRY1 and phyB. Nature 410:487-490.
39. Kim ST, Malhotra K, Ryo H, Sancar A, and Todo T (1996) Purification and characterization of Drosophila melanogaster photolyase. Mutat Res 363:97-104.
40. Kiyosue T and Wada M (2000) LKP1 (LOV kelch protein 1): A factor involved in the regulation of flowering time in Arabidopsis. Plant J 23:807-815.
41. Kobayashi Y, Ishikawa T, Hirayama J, Daiyasu H, Kanai S, Toh H, Fukuda I, Tsujimura T, Terada N, Kamei Y, Yuba S, Iwai S, and Todo T (2000) Molecular analysis of zebrafish photolyase/cryptochrome family: Two types of cryptochromes present in zebrafish. Genes Cells 5:725-738.
42. Kojima D and Fukada Y (1999) Non-visual photoreception by a variety of vertebrate opsins. Novartis Foundation Symposium 224:265-279; discussion 279-282.
43. Kreps JA and Simon AE (1997) Environmental and genetic effects on circadian clock-regulated gene expression in Arabidopsis. Plant Cell 9:297-304.
44. Krishnan B, Dryer SE, and Hardin PE (1999) Circadian rhythms in olfactory responses of Drosophila melanogaster. Nature 400:375-378.
45. Krishnan B, Levine JD, Lynch MK, Dowse HB, Funes P, Hall JC, Hardin PE, and Dryer SE (2001) A new role for cryptochrome in a Drosophila circadian oscillator. Nature 411:313-317.
46. Kume K, Zylka MJ, Sriram S, Shearman LP, Weaver DR, Jin X, Maywood ES, Hastings MH, and Reppert SM (1999) mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop. Cell 98:193-205.
47. Lee C, Parikh V, Itsukaichi T, Bae K, and Edery I (1996) Resetting the Drosophila clock by photic regulation of PER and a PER-TIM complex. Science 271:1740-1744.
48. Lin C, Ahmad M, Gordon D, and Cashmore AR (1995a) Expression of an Arabidopsis cryptochrome gene in transgenic tobacco results in hypersensitivity to blue, UV-A, and green light. Proc Natl Acad Sci U S A 92:8423-8427.
49. Lin C, Robertson DE, Ahmad M, Raibekas AA, Jorns MS, Dutton PL, and Cashmore AR (1995b) Association of flavin adenine dinucleotide with the Arabidopsis blue light receptor CRY1. Science 269:968-970.
50. Lin C, Yang H, Guo H, Mockler T, Chen J, and Caskmore AR (1998) Enhancement of blue-light sensitivity of Arabidopsis seedlings by a blue light receptor cryptochrome 2. Proc Natl Acad Sci U S A 95:2686-2690.
51. Lin FJ, Song W, Meyer-Bernstein E, Naidoo N, and Sehgal A (2001) Photic signaling by cryptochrome in the Drosophila circadian system. Mol Cell Biol 21:7287-7294.
52. Lucas RJ, Douglas RH, and Foster RG (2001) Characterization of an ocular photopigment capable of driving pupillary constriction in mice. Nat Neurosci 4:621-626.
53. Lucas RJ, Freedman MS, Munoz M, Garcia-Fernandez JM, and Foster RG (1999) Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors. Science 284:505-507.
54. Mas P, Devlin PF, Panda S, and Kay SA (2000) Functional interaction of phytochrome B and cryptochrome 2. Nature 408:207-211.
55. McDonald M and Rosbash M (2001) Microarray analysis and organization of circadian gene expression in Drosophila. Cell 107:567-578.
56. McWatters HG, Bastow RM, Hall A, and Millar AJ (2000) The ELF3 zeitnehmer regulates light signalling to the circadian clock. Nature 408:716-720.
57. Merrow M, Franchi L, Dragovic Z, Gorl M, Johnson J, Brunner M, Macino G, and Roenneberg T (2001) Circadian regulation of the light input pathway in Neurospora crassa. EMBO J 20:307-315.
58. Miyamoto Y and Sancar A (1998) Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals. Proc Natl Acad Sci U S A 95:6097-6102.
59. Miyamoto Y and Sancar A (1999) Circadian regulation of cryptochrome genes in the mouse. Brain Res Mol Brain Res 71:238-243.
60. Mrosovsky N (2001) Further characterization of the phenotype of mCry1/mCry2-deficient mice. Chronobiol Int 18:613-625.
61. Mrosovsky N, Foster R, and Salmon P (1999) Thresholds for masking responses in light in three strains of retinally degenerate mice. J Comp Physiol A 184:423-428.
62. Myers MP, Wager-Smith K, Rothenfluh-Hilfiker A, and Young MW (1996) Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock. Science 271:1736-1740.
63. Naidoo N, Song W, Hunter-Ensor M, and Sehgal A (1999) A role for the proteasome in the light response of the Timeless clock protein. Science 285:1737-1741.
64. Okamura H, Miyake S, Sumi Y, Yamaguchi S, Yasui A, Muijens M, Hoeijmakers JH, and van der Horst GT (1999) Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock. Science 286:2531-2534.
65. Pando MP, Pinchak AB, Cermakian N, and Sassone-Corsi P (2001) A cell-based system that recapitulates the dynamic light-dependent regulation of the vertebrate clock. Proc Natl Acad Sci U S A 98:10178-10183.
66. Plautz JD, Kaneko M, Hall JC, and Kay SA (1997) Independent photoreceptive circadian clocks throughout Drosophila. Science 278:1632-1635.
67. Provencio I and Foster RG (1995) Circadian rhythms in mice can be regulated by photoreceptors with cone-like characteristics. Brain Res 694:183-190.
68. Provencio I, Jiang G, De Grip WJ, Hayes WP, and Rollag MD (1998) Melanopsin: An opsin in melanophores, brain, and eye. Proc Natl Acad Sci U S A 95:340-345.
69. Provencio I, Rodriguez IR, Jiang G, Hayes WP, Moreira EF, and Rollag MD (2000) A novel human opsin in the inner retina. J Neurosci 20:600-605.
70. Quadro L, Blaner WS, Salchow DJ, Vogel S, Piantedosi R, Gouras P, Freeman S, Cosma MP, Colantuoni V, and Gottesman ME (1999) Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein. EMBO J 18:4633-4644.
71. Rosato E, Codd V, Mazzotta G, Piccin A, Zordan M, Costa R, and Kyriacou CP (2001) Light-dependent interaction between Drosophila CRY and the clock protein PER mediated by the carboxy terminus of CRY. Curr Biol 11:909-917.
72. Sancar A (1996) No "end of history" for photolyases. Science 272:48-49.
73. Sancar A (2000) Cryptochrome: The second photoactive pigment in the eye and its role in circadian photoreception. Annu Rev Biochem 69:31-67.
74. Selby CP and Sancar A (1999) A third member of the photolyase/blue-light photoreceptor family in Drosophila: A putative circadian photoreceptor. Photochem Photobiol 69:105-107.
75. Selby CP, Thompson C, Schmitz TM, Van Gelder RN, and Sancar A (2000) Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice. Proc Natl Acad Sci U S A 97:14697-14702.
76. Shearman LP, Sriram S, Weaver DR, Maywood ES, Chaves I, Zheng B, Kume K, Lee CC, van der Horst GT, Hastings MH, and Reppert SM (2000) Interacting molecular loops in the mammalian circadian clock. Science 288:1013-1019.
77. Smolen P, Baxter DA, and Byrne JH (2001) Modeling circadian oscillations with interlocking positive and negative feedback loops. J Neurosci 21:6644-6656.
78. Somers DE, Devlin PF, and Kay SA (1998) Phytochromes and cryptochromes in the entrainment of the Arabidopsis circadian clock. Science 282:1488-1490.
79. Somers DE, Schultz TF, Milnamow M, and Kay SA (2000) ZEITLUPE encodes a novel clock-associated PAS protein from Arabidopsis. Cell 101:319-329.
80. Stanewsky R, Kaneko M, Emery P, Beretta B, Wagersmith K, Kay SA, Rosbash M, and Hall JC (1998) The cry(b) mutation identifies cryptochrome as a circadian photoreceptor in Drosophila. Cell 95:681-692.
81. Swartz TE, Corchnoy SB, Christie JM, Lewis JW, Szundi I, Briggs WR, and Bogomolni RA (2001) The photocycle of a flavin-binding domain of the blue light photoreceptor phototropin. J Biol Chem 276:36493-36500.
82. Tao L, Shen D, Pandey S, Hao W, Rich KA, and Fong HK (1998) Structure and developmental expression of the mouse RGR opsin gene. Mol Vis 4:25.
83. Thapan K, Arendt J, and Skene DJ (2001) An action spectrum for melatonin suppression: Evidence for a novel non-rod, non-cone photoreceptor system in humans. J Physiol 535:261-267.
84. Thompson CL, Blaner WS, Van Gelder RN, Lai K, Quadro L, Colantuoni V, Gottesman ME, and Sancar A (2001) Preservation of light-signaling to the suprachiasmatic nucleus in vitamin-A deficient mice. Proc Natl Acad Sci U S A 98:11708-11713.
85. Thresher RJ, Vitaterna MH, Miyamoto Y, Kazantsev A, Hsu DS, Petit C, Selby CP, Dawut L, Smithies O, Takahashi JS, and Sancar A (1998) Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. Science 282:1490-1494.
86. Todo T, Ryo H, Yamamoto K, Toh H, Inui T, Ayaki H, Nomura T, and Ikenaga M (1996) Similarity among the Drosophila (6-4)photolyase, a human photolyase homolog, and the DNA photolyase-blue-light photoreceptor family. Science 272:109-112.
87. van der Horst GT, Muijtjens M, Kobayashi K, Takano R, Kanno S, Takao M, de Wit J, Verkerk A, Eker AP, van Leenen D, Buijs R, Bootsma D, Hoeijmakers JH, and Yasui A (1999) Mammalian Cryl and Cry2 are essential for maintenance of circadian rhythms. Nature 398:627-630.
88. van der Spek PJ, Kobayashi K, Bootsma D, Takao M, Eker AP, and Yasui A (1996) Cloning, tissue expression, and mapping of a human photolyase homolog with similarity to plant blue-light receptors. Genomics 37:177-182.
89. Vitaterna MH, Selby CP, Todo T, Niwa H, Thompson C, Fruechte EM, Hitomi K, Thresher RJ, Ishikawa T, Miyazaki J, Takahashi JS, and Sancar A (1999) Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc Natl Acad Sci U S A 96:12114-12119.
90. Wang H, Ma LG, Li JM, Zhao HY, and Deng XW (2001) Direct interaction of Arabidopsis cryptochromes with COP1 in light control development. Science 294:154-158.
91. Wheeler DA, Hamblen-Coyle MJ, Dushay MS, and Hall JC (1993) Behavior in light-dark cycles of Drosophila mutants that are arrhythmic, blind, or both. J Biol Rhythms 8:67-94.
92. Whitmore D, Foulkes NS, and Sassone-Corsi P (2000) Light acts directly on organs and cells in culture to set the vertebrate circadian clock. Nature 404:87-91.
93. Yagita K, Tamanini F, van der Horst GT, and Okamura H (2001) Molecular mechanisms of the biological clock in cultured fibroblasts. Science 292:278-281.
94. Yamamoto K, Okano T, and Fukada Y (2001) Chicken pineal Cry genes: Light-dependent up-regulation of cCry1 and cCry2 transcripts. Neurosci Lett 313:13-16.
95. Yanovsky MJ, Mazzella MA, and Casal JJ (2000) A quadruple photoreceptor mutant still keeps track of time. Curr Biol 10:1013-1015.
96. Zeng H, Qian Z, Myers MP, and Rosbash M (1996) A light-entrainment mechanism for the Drosophila circadian clock. Nature 380:129-135.
97. Zhao S and Sancar A (1997) Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity. Photochem Photobiol 66:727-731.
98. Zhong HH, Resnick AS, Straume M, and McClung CR (1997) Effects of synergistic signaling by phytochrome A and cryptochromel on circadian clock-regulated catalase expression. Plant Cell 9:947-955.
99. Zhu H and Green CB (2001a) A putative flavin electron transport pathway is differentially utilized in Xenopus CRY1 and CRY2. Curr Biol 11:1945-1949.
100. Zhu H and Green CB (2001b) Three cryptochromes are rhythmically expressed in Xenopus laevis retinal photoreceptors. Mol Vis 7:210-215.
101. Zimmerman WF and Goldsmith TH (1971) Photosensitivity of the circadian rhythm and of visual receptors in carotenoid-depleted Drosophila. Science 171:1167-1169.