-
1
-
-
0028946238
-
-
J. C. Hall, Trends Neurosci. 18, 230 (1995); J. S. Takahashi, Annu. Rev. Neurosci. 18, 531 (1995); J. C. Dunlap, Annu. Rev. Genet. 30, 579 (1996); C. H. Johnson, S. G. Golden, M. Ishiura, T. Kondo, Mol. Microbiol. 21, 5 (1996); R. Y. Moore, Annu. Rev. Med. 48, 253 (1997); M. W. Young, Annu. Rev. Biochem. 67, 135 (1998).
-
(1995)
Trends Neurosci.
, vol.18
, pp. 230
-
-
Hall, J.C.1
-
2
-
-
0028915430
-
-
J. C. Hall, Trends Neurosci. 18, 230 (1995); J. S. Takahashi, Annu. Rev. Neurosci. 18, 531 (1995); J. C. Dunlap, Annu. Rev. Genet. 30, 579 (1996); C. H. Johnson, S. G. Golden, M. Ishiura, T. Kondo, Mol. Microbiol. 21, 5 (1996); R. Y. Moore, Annu. Rev. Med. 48, 253 (1997); M. W. Young, Annu. Rev. Biochem. 67, 135 (1998).
-
(1995)
Annu. Rev. Neurosci.
, vol.18
, pp. 531
-
-
Takahashi, J.S.1
-
3
-
-
0030299960
-
-
J. C. Hall, Trends Neurosci. 18, 230 (1995); J. S. Takahashi, Annu. Rev. Neurosci. 18, 531 (1995); J. C. Dunlap, Annu. Rev. Genet. 30, 579 (1996); C. H. Johnson, S. G. Golden, M. Ishiura, T. Kondo, Mol. Microbiol. 21, 5 (1996); R. Y. Moore, Annu. Rev. Med. 48, 253 (1997); M. W. Young, Annu. Rev. Biochem. 67, 135 (1998).
-
(1996)
Annu. Rev. Genet.
, vol.30
, pp. 579
-
-
Dunlap, J.C.1
-
4
-
-
0030035254
-
-
J. C. Hall, Trends Neurosci. 18, 230 (1995); J. S. Takahashi, Annu. Rev. Neurosci. 18, 531 (1995); J. C. Dunlap, Annu. Rev. Genet. 30, 579 (1996); C. H. Johnson, S. G. Golden, M. Ishiura, T. Kondo, Mol. Microbiol. 21, 5 (1996); R. Y. Moore, Annu. Rev. Med. 48, 253 (1997); M. W. Young, Annu. Rev. Biochem. 67, 135 (1998).
-
(1996)
Mol. Microbiol.
, vol.21
, pp. 5
-
-
Johnson, C.H.1
Golden, S.G.2
Ishiura, M.3
Kondo, T.4
-
5
-
-
0031040501
-
-
J. C. Hall, Trends Neurosci. 18, 230 (1995); J. S. Takahashi, Annu. Rev. Neurosci. 18, 531 (1995); J. C. Dunlap, Annu. Rev. Genet. 30, 579 (1996); C. H. Johnson, S. G. Golden, M. Ishiura, T. Kondo, Mol. Microbiol. 21, 5 (1996); R. Y. Moore, Annu. Rev. Med. 48, 253 (1997); M. W. Young, Annu. Rev. Biochem. 67, 135 (1998).
-
(1997)
Annu. Rev. Med.
, vol.48
, pp. 253
-
-
Moore, R.Y.1
-
6
-
-
0031715040
-
-
J. C. Hall, Trends Neurosci. 18, 230 (1995); J. S. Takahashi, Annu. Rev. Neurosci. 18, 531 (1995); J. C. Dunlap, Annu. Rev. Genet. 30, 579 (1996); C. H. Johnson, S. G. Golden, M. Ishiura, T. Kondo, Mol. Microbiol. 21, 5 (1996); R. Y. Moore, Annu. Rev. Med. 48, 253 (1997); M. W. Young, Annu. Rev. Biochem. 67, 135 (1998).
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 135
-
-
Young, M.W.1
-
10
-
-
0001275285
-
-
S. S. Campbell and P. J. Murphy, Science 279, 396 (1998); D. Oren, Neuroscientist 2, 207 (1996).
-
(1996)
Neuroscientist
, vol.2
, pp. 207
-
-
Oren, D.1
-
11
-
-
0029903498
-
-
D.S. Hsu et al., Biochemistry 35, 13871 (1996).
-
(1996)
Biochemistry
, vol.35
, pp. 13871
-
-
Hsu, D.S.1
-
13
-
-
0027493250
-
-
M. Ahmad and A. R. Cashmore, Nature 366, 162 (1993); A. Batschauer, Plant J. 4, 705 (1993).
-
(1993)
Nature
, vol.366
, pp. 162
-
-
Ahmad, M.1
Cashmore, A.R.2
-
14
-
-
0027673186
-
-
M. Ahmad and A. R. Cashmore, Nature 366, 162 (1993); A. Batschauer, Plant J. 4, 705 (1993).
-
(1993)
Plant J.
, vol.4
, pp. 705
-
-
Batschauer, A.1
-
15
-
-
0029061519
-
-
K. Malhotra et al., Biochemistry 34, 6892 (1995); C. Lin et al., Science 269, 968 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 6892
-
-
Malhotra, K.1
-
16
-
-
0029127546
-
-
K. Malhotra et al., Biochemistry 34, 6892 (1995); C. Lin et al., Science 269, 968 (1995).
-
(1995)
Science
, vol.269
, pp. 968
-
-
Lin, C.1
-
18
-
-
0032570771
-
-
G. Guo, H. Yang, T. C. Mockler, C. Lin, Science 279, 1360 (1998).
-
(1998)
Science
, vol.279
, pp. 1360
-
-
Guo, G.1
Yang, H.2
Mockler, T.C.3
Lin, C.4
-
19
-
-
0032537186
-
-
M. Ahmad, J. A. Jarillo, O. Smirnova, A. R. Cashmore, Nature 393, 720 (1998).
-
(1998)
Nature
, vol.393
, pp. 720
-
-
Ahmad, M.1
Jarillo, J.A.2
Smirnova, O.3
Cashmore, A.R.4
-
20
-
-
0010417982
-
-
M. D. Adams et al., ibid. 377, 1 (1995); T. Todo et al., Science 272, 109 (1996); P. J. van der Spek et al., Genomics 37, 177 (1996). GenBank accession numbers for the mouse genes are AB000777 (Cry1) and AB003433 (Cry2).
-
(1995)
Nature
, vol.377
, pp. 1
-
-
Adams, M.D.1
-
21
-
-
0029914630
-
-
M. D. Adams et al., ibid. 377, 1 (1995); T. Todo et al., Science 272, 109 (1996); P. J. van der Spek et al., Genomics 37, 177 (1996). GenBank accession numbers for the mouse genes are AB000777 (Cry1) and AB003433 (Cry2).
-
(1996)
Science
, vol.272
, pp. 109
-
-
Todo, T.1
-
22
-
-
0030588098
-
-
M. D. Adams et al., ibid. 377, 1 (1995); T. Todo et al., Science 272, 109 (1996); P. J. van der Spek et al., Genomics 37, 177 (1996). GenBank accession numbers for the mouse genes are AB000777 (Cry1) and AB003433 (Cry2).
-
(1996)
Genomics
, vol.37
, pp. 177
-
-
Van Der Spek, P.J.1
-
23
-
-
0028812143
-
-
1) were back-crossed to C57BL/6 animals to obtain progeny that were interbred to produce the experimental animals used in this study. Genotypic analysis of these progeny was by DNA hybridization. Subsequent screening was by PCR alone as there was complete agreement. Analyses of homozygotes by Northern (RNA) hybridization and in situ hybridization revealed a complete lack of Cry2 mRNA in the mutants.
-
(1995)
Science
, vol.268
, pp. 1866
-
-
Park, H.-W.1
Kim, S.-T.2
Sancar, A.3
Deisenhofer, J.4
-
24
-
-
0030694239
-
-
1) were back-crossed to C57BL/6 animals to obtain progeny that were interbred to produce the experimental animals used in this study. Genotypic analysis of these progeny was by DNA hybridization. Subsequent screening was by PCR alone as there was complete agreement. Analyses of homozygotes by Northern (RNA) hybridization and in situ hybridization revealed a complete lack of Cry2 mRNA in the mutants.
-
(1997)
Nature Struct. Biol.
, vol.4
, pp. 887
-
-
Tamada, T.1
-
25
-
-
0023150598
-
-
1) were back-crossed to C57BL/6 animals to obtain progeny that were interbred to produce the experimental animals used in this study. Genotypic analysis of these progeny was by DNA hybridization. Subsequent screening was by PCR alone as there was complete agreement. Analyses of homozygotes by Northern (RNA) hybridization and in situ hybridization revealed a complete lack of Cry2 mRNA in the mutants.
-
(1987)
Nature
, vol.326
, pp. 292
-
-
Hooper, M.1
-
26
-
-
0024296027
-
-
1) were back-crossed to C57BL/6 animals to obtain progeny that were interbred to produce the experimental animals used in this study. Genotypic analysis of these progeny was by DNA hybridization. Subsequent screening was by PCR alone as there was complete agreement. Analyses of homozygotes by Northern (RNA) hybridization and in situ hybridization revealed a complete lack of Cry2 mRNA in the mutants.
-
(1988)
Nature
, vol.336
, pp. 348
-
-
Mansour, S.L.1
Thomas, K.R.2
Copecchi, M.R.3
-
27
-
-
0030800739
-
-
H. Tei et al., Nature 389, 512 (1997); S. Sun et al., Cell 90, 1003 (1997).
-
(1997)
Nature
, vol.389
, pp. 512
-
-
Tei, H.1
-
28
-
-
0030885313
-
-
H. Tei et al., Nature 389, 512 (1997); S. Sun et al., Cell 90, 1003 (1997).
-
(1997)
Cell
, vol.90
, pp. 1003
-
-
Sun, S.1
-
29
-
-
0031459479
-
-
Y. Shigeyoshi et al., Cell 91, 1043 (1997); U. Albrecht, Z. Sun, G. Eichele, C. Lee, ibid., p. 1055.
-
(1997)
Cell
, vol.91
, pp. 1043
-
-
Shigeyoshi, Y.1
-
30
-
-
0031459479
-
-
Y. Shigeyoshi et al., Cell 91, 1043 (1997); U. Albrecht, Z. Sun, G. Eichele, C. Lee, ibid., p. 1055.
-
Cell
, pp. 1055
-
-
Albrecht, U.1
Sun, Z.2
Eichele, G.3
Lee, C.4
-
31
-
-
0026048367
-
-
It is possible that "masking" or inhibition of activity by bright light contributes to the entrainment of the mutant mice, because activity feedback can have a strong phase-resetting effects in rodents [D. M. Edgar and W. C. Dement, Am. J. Physiol. 261, R928 (1991); C. R. Wickland and F. W. Turek, ibid., p. R1109].
-
(1991)
Am. J. Physiol.
, vol.261
-
-
Edgar, D.M.1
Dement, W.C.2
-
32
-
-
0026048367
-
-
It is possible that "masking" or inhibition of activity by bright light contributes to the entrainment of the mutant mice, because activity feedback can have a strong phase-resetting effects in rodents [D. M. Edgar and W. C. Dement, Am. J. Physiol. 261, R928 (1991); C. R. Wickland and F. W. Turek, ibid., p. R1109].
-
Am. J. Physiol.
-
-
Wickland, C.R.1
Turek, F.W.2
-
33
-
-
3643072457
-
-
note
-
The animal was transferred in its home cage to a different cabinet and exposed to a saturating light pulse that consisted of a 6-hour exposure to 36-W 4-foot fluorescent "cool white" (General Electric) light 25 cm above the cage lid (300 to 350 lux). The exposure time was chosen to achieve the maximal responses to light pulses.
-
-
-
-
34
-
-
0343504262
-
-
2 periodogram [P. G. Sokolova and W. N. Bushel, Fed. Proc. 38, 2589 (1978)] from 10 consecutive days when no manipulations were performed: days 5 to 15 in DD and several weeks later after three light pulses had been given. Data were analyzed by a Generalized Model (GLM) analysis of variance (ANOVA) by using NCSS, with Scheffe's post-hoc tests for pairwise comparisons.
-
(1978)
Fed. Proc.
, vol.38
, pp. 2589
-
-
Sokolova, P.G.1
Bushel, W.N.2
-
36
-
-
70449271896
-
-
J. Aschoff, Cold Spring Harbor Symp. Quant. Biol. 25, 11 (1960); J. Aschoff, Z. Tierpsychol. 49, 2225 (1979).
-
(1979)
Z. Tierpsychol.
, vol.49
, pp. 2225
-
-
Aschoff, J.1
-
37
-
-
0000689128
-
-
J. W. Hastings and B. M. Sweeney, Biol. Bull. 115, 440 (1958); S. Daan and C. S. Pittendrigh, J. Comp. Physiol. 106, 253 (1976); W. J. Schwartz and P. Zimmerman, J. Neurosci. 10, 3685 (1990).
-
(1958)
Biol. Bull.
, vol.115
, pp. 440
-
-
Hastings, J.W.1
Sweeney, B.M.2
-
38
-
-
0017198155
-
-
J. W. Hastings and B. M. Sweeney, Biol. Bull. 115, 440 (1958); S. Daan and C. S. Pittendrigh, J. Comp. Physiol. 106, 253 (1976); W. J. Schwartz and P. Zimmerman, J. Neurosci. 10, 3685 (1990).
-
(1976)
J. Comp. Physiol.
, vol.106
, pp. 253
-
-
Daan, S.1
Pittendrigh, C.S.2
-
39
-
-
0025514411
-
-
J. W. Hastings and B. M. Sweeney, Biol. Bull. 115, 440 (1958); S. Daan and C. S. Pittendrigh, J. Comp. Physiol. 106, 253 (1976); W. J. Schwartz and P. Zimmerman, J. Neurosci. 10, 3685 (1990).
-
(1990)
J. Neurosci.
, vol.10
, pp. 3685
-
-
Schwartz, W.J.1
Zimmerman, P.2
-
40
-
-
3643122522
-
-
note
-
Results of a one-way GLM ANOVA for phase shifts to light pulses at CT 17.4 ± 0.9 (range CT16.5 to 18.3) indicate a significant effect of the Cry2 genotype (P = 0.01548, F = 5.03). Post-hoc pairwise comparisons of wild-type versus mutant animals yields P < 0.05 with Bonferroni, Duncun's, Neuman-Keuls, and Tukey-Kramer multiple comparisons tests.
-
-
-
-
42
-
-
0025953998
-
-
R. Rossenberg et al. Am. J. Physiol. 261, R491 (1991); Y. Zhang et al., Neuroscience 70, 951 (1996).
-
(1991)
Am. J. Physiol.
, vol.261
-
-
Rossenberg, R.1
-
43
-
-
0030056990
-
-
R. Rossenberg et al. Am. J. Physiol. 261, R491 (1991); Y. Zhang et al., Neuroscience 70, 951 (1996).
-
(1996)
Neuroscience
, vol.70
, pp. 951
-
-
Zhang, Y.1
-
44
-
-
0031413780
-
-
V. S. Valentinuzzi et al., Am. J. Physiol. 273, R1957 (1997); S. Benloucif, M. I. Mosana, M. L. Dubocovich, Brain Res. 747, 34 (1997).
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Valentinuzzi, V.S.1
-
45
-
-
0031055918
-
-
V. S. Valentinuzzi et al., Am. J. Physiol. 273, R1957 (1997); S. Benloucif, M. I. Mosana, M. L. Dubocovich, Brain Res. 747, 34 (1997).
-
(1997)
Brain Res.
, vol.747
, pp. 34
-
-
Benloucif, S.1
Mosana, M.I.2
Dubocovich, M.L.3
-
46
-
-
0024773180
-
-
C. H. Johnson and J. W. Hastings, J. Biol. Rhythms 4, 417 (1989); T. Ronnenberg and J. W. Hastings, Naturwiss 75, 206 (1988); X. Deng and T. Ronnenberg, Planta 202, 502 (1997); T. Ronnenberg and X. Deng, ibid., p. 494.
-
(1989)
J. Biol. Rhythms
, vol.4
, pp. 417
-
-
Johnson, C.H.1
Hastings, J.W.2
-
47
-
-
0023892516
-
-
C. H. Johnson and J. W. Hastings, J. Biol. Rhythms 4, 417 (1989); T. Ronnenberg and J. W. Hastings, Naturwiss 75, 206 (1988); X. Deng and T. Ronnenberg, Planta 202, 502 (1997); T. Ronnenberg and X. Deng, ibid., p. 494.
-
(1988)
Naturwiss
, vol.75
, pp. 206
-
-
Ronnenberg, T.1
Hastings, J.W.2
-
48
-
-
0030795811
-
-
C. H. Johnson and J. W. Hastings, J. Biol. Rhythms 4, 417 (1989); T. Ronnenberg and J. W. Hastings, Naturwiss 75, 206 (1988); X. Deng and T. Ronnenberg, Planta 202, 502 (1997); T. Ronnenberg and X. Deng, ibid., p. 494.
-
(1997)
Planta
, vol.202
, pp. 502
-
-
Deng, X.1
Ronnenberg, T.2
-
49
-
-
0024773180
-
-
C. H. Johnson and J. W. Hastings, J. Biol. Rhythms 4, 417 (1989); T. Ronnenberg and J. W. Hastings, Naturwiss 75, 206 (1988); X. Deng and T. Ronnenberg, Planta 202, 502 (1997); T. Ronnenberg and X. Deng, ibid., p. 494.
-
Planta
, pp. 494
-
-
Ronnenberg, T.1
Deng, X.2
-
50
-
-
0028956524
-
-
A. J. Millar, M. Straume, J. Chory, N.-H. Chua, S. A. Kay, Science 267, 1163 (1995).
-
(1995)
Science
, vol.267
, pp. 1163
-
-
Millar, A.J.1
Straume, M.2
Chory, J.3
Chua, N.-H.4
Kay, S.A.5
-
51
-
-
0021059965
-
-
K. Yamamoto, Y. Fujiwara, H. Shinagawa, Mol. Gen. Genet. 192, 282 (1983); A. Sancar, K. A. Franklin, G. B. Sancar, Proc. Natl. Acad. Sci. U.S.A. 81, 7397 (1984); J. B. Hays and S. J. Martin, Mol. Cell. Biol. 9, 767 (1984); M. E. Fox, B. J. Felman, G. Chu, ibid. 14, 8071 (1994); Z. Ozer et al., Biochemistry 34, 15886 (1995).
-
(1983)
Mol. Gen. Genet.
, vol.192
, pp. 282
-
-
Yamamoto, K.1
Fujiwara, Y.2
Shinagawa, H.3
-
52
-
-
0038434901
-
-
K. Yamamoto, Y. Fujiwara, H. Shinagawa, Mol. Gen. Genet. 192, 282 (1983); A. Sancar, K. A. Franklin, G. B. Sancar, Proc. Natl. Acad. Sci. U.S.A. 81, 7397 (1984); J. B. Hays and S. J. Martin, Mol. Cell. Biol. 9, 767 (1984); M. E. Fox, B. J. Felman, G. Chu, ibid. 14, 8071 (1994); Z. Ozer et al., Biochemistry 34, 15886 (1995).
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.81
, pp. 7397
-
-
Sancar, A.1
Franklin, K.A.2
Sancar, G.B.3
-
53
-
-
0021059965
-
-
K. Yamamoto, Y. Fujiwara, H. Shinagawa, Mol. Gen. Genet. 192, 282 (1983); A. Sancar, K. A. Franklin, G. B. Sancar, Proc. Natl. Acad. Sci. U.S.A. 81, 7397 (1984); J. B. Hays and S. J. Martin, Mol. Cell. Biol. 9, 767 (1984); M. E. Fox, B. J. Felman, G. Chu, ibid. 14, 8071 (1994); Z. Ozer et al., Biochemistry 34, 15886 (1995).
-
(1984)
Mol. Cell. Biol.
, vol.9
, pp. 767
-
-
Hays, J.B.1
Martin, S.J.2
-
54
-
-
0027959686
-
-
K. Yamamoto, Y. Fujiwara, H. Shinagawa, Mol. Gen. Genet. 192, 282 (1983); A. Sancar, K. A. Franklin, G. B. Sancar, Proc. Natl. Acad. Sci. U.S.A. 81, 7397 (1984); J. B. Hays and S. J. Martin, Mol. Cell. Biol. 9, 767 (1984); M. E. Fox, B. J. Felman, G. Chu, ibid. 14, 8071 (1994); Z. Ozer et al., Biochemistry 34, 15886 (1995).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8071
-
-
Fox, M.E.1
Felman, B.J.2
Chu, G.3
-
55
-
-
0028820253
-
-
K. Yamamoto, Y. Fujiwara, H. Shinagawa, Mol. Gen. Genet. 192, 282 (1983); A. Sancar, K. A. Franklin, G. B. Sancar, Proc. Natl. Acad. Sci. U.S.A. 81, 7397 (1984); J. B. Hays and S. J. Martin, Mol. Cell. Biol. 9, 767 (1984); M. E. Fox, B. J. Felman, G. Chu, ibid. 14, 8071 (1994); Z. Ozer et al., Biochemistry 34, 15886 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 15886
-
-
Ozer, Z.1
-
56
-
-
0039990682
-
-
J. B. Hoganesch, Y.-Z. Gu, S. Jain, C. A. Bradfield, Proc. Natl. Acad. Soc. U.S.A. 95, 5744 (1998); N. Gekakis et al., Science 280, 1564 (1998).
-
(1998)
Proc. Natl. Acad. Soc. U.S.A.
, vol.95
, pp. 5744
-
-
Hoganesch, J.B.1
Gu, Y.-Z.2
Jain, S.3
Bradfield, C.A.4
-
57
-
-
0032486330
-
-
J. B. Hoganesch, Y.-Z. Gu, S. Jain, C. A. Bradfield, Proc. Natl. Acad. Soc. U.S.A. 95, 5744 (1998); N. Gekakis et al., Science 280, 1564 (1998).
-
(1998)
Science
, vol.280
, pp. 1564
-
-
Gekakis, N.1
-
58
-
-
0032486432
-
-
T. K. Darlington et al., Science 280, 1599 (1998); R. Allada et al., Cell 93, 805 (1998).
-
(1998)
Science
, vol.280
, pp. 1599
-
-
Darlington, T.K.1
-
59
-
-
0032486432
-
-
T. K. Darlington et al., Science 280, 1599 (1998); R. Allada et al., Cell 93, 805 (1998).
-
(1998)
Cell
, vol.93
, pp. 805
-
-
Allada, R.1
-
62
-
-
0014674183
-
-
K. D. Frank and W. F. Zimmerman, Science 163, 688 (1969); E. Klemm and H. Ninnemann, Photochem. Photobiol. 24, 371 (1976).
-
(1969)
Science
, vol.163
, pp. 688
-
-
Frank, K.D.1
Zimmerman, W.F.2
-
66
-
-
0032125727
-
-
Z. Yang, M. Emerson, H. S. Su, A. Sehgal, Neuron 21, 215 (1998).
-
(1998)
Neuron
, vol.21
, pp. 215
-
-
Yang, Z.1
Emerson, M.2
Su, H.S.3
Sehgal, A.4
-
67
-
-
3643078778
-
-
V. Suri, Z. Qian, J. C. Hall, M. Rosbach, ibid., p. 225.
-
Neuron
, pp. 225
-
-
Suri, V.1
Qian, Z.2
Hall, J.C.3
Rosbach, M.4
-
71
-
-
3643077753
-
-
note
-
Supported by NIH grants GM31082 (A.S.) and GM20069 (O.S.) and the NSF Center for Biological Timing and NIH grant PO AG11412 (J.S.T.). J.S.T. is an investigator in the Howard Hughes Medical Institute.
-
-
-
|