Ephrin-As as receptors in topographic projections

Trends in Neurosciences

Volumn 25, Issue 3, 2002, Pages 145-149

  Knöll, Bernd ^a   Drescher, Uwe ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN; EPHRIN RECEPTOR; GLYCOSYLPHOSPHATIDYLINOSITOL; ISOPROTEIN;

ANGIOGENESIS; BRAIN DEVELOPMENT; CELL MIGRATION; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINOTECTAL PROJECTION; REVIEW; SIGNAL TRANSDUCTION; VOMERONASAL ORGAN;

ANIMALS; BODY PATTERNING; BRAIN; CELL COMMUNICATION; CELL DIFFERENTIATION; EPHRIN-A1; GROWTH CONES; HUMANS; PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPHA1; VISUAL PATHWAYS; VOMERONASAL ORGAN;

EID: 0036498380     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(00)02093-2     Document Type: Review

References (62)

1. Multiple roles of Eph receptors and ephrins in neural development
2. Molecular development of sensory maps: Representing sights and smells in the brain
3. Topographic mapping: Organising by repulsion and competition?
4. The ephrins and Eph receptors in neural development
5. Excitatory Eph receptors and adhesive ephrin ligands
6. Eph receptors and ephrins in neural development
7. Eph receptors and ephrin ligands: Embryogenesis to tumorigenesis
8. Lipid rafts and signal transduction
9. Compartmentalized signaling by GPI-anchored ephrinA5 requires the fyn tyrosine kinase to regulate cellular adhesion
10. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains
11. Eph receptors and ephrins restrict cell intermingling and communication
12. In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins
13. Eph family receptors and their ligands distribute in opposing gradients in the developing mouse retina
14. Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the visual system
15. Modulation of EphA receptor function by coexpressed ephrin-A ligands on retinal ganglion cell axons
16. A role for the EphA family in the topographic targeting of vomeronasal axons
17. Model for the retinotectal projection
18. Chemoaffinity in the orderly growth of nerve fiber patters and connections
19. Development of the visual system of the chick. I. Cell differentiation and histogenesis
20. Development of the visual system of the chick. II. Mechanisms of axonal guidance
21. The Eph family in retinal axon guidance
22. Differential expression of Eph receptors and ephrins correlates with the formation of topographic projections in primary and secondary visual circuits of the embryonic chick forebrain
23. Identification of alternatively spliced mRNAs encoding variants of MDK1, a novel receptor tyrosine kinase expressed in the murine nervous system
24. Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping
25. Topographic targeting and pathfinding errors of retinal axons following overexpression of ephrin-A ligands on retinal ganglion cell axons
26. Ventroptin: A BMP-4 antagonist expressed in a double-gradient pattern in the retina
27. Visual projection map specified by topographic expression of transcription factors in the retina
28. Regulatory interrelations among topographic molecules CBF1, CBF2 and EphA3 in the developing chick retina
29. Two homeobox genes define the domain of EphA3 expression in the developing chick retina
30. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling
31. Retinotectal maps: Molecules, models and misplaced data
32. Reading of concentration gradients by axonal growth cones
33. Topographic-specific axon branching controlled by ephrin-As is the critical event in retinotectal map development
34. Ephrin-A6, a new ligand for EphA receptors in the developing visual system
35. Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline
36. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
37. Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control
38. The cytoplasmic domain of the ligand ephrin-B2 is required for vascular morphogenesis but not cranial neural crest migration
39. Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo
40. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development
41. Sensory coding of pheromone signals in mammals
42. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium
43. Topographic organization of sensory projections to the olfactory bulb
44. Visualizing an olfactory sensory map
45. Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system
46. A map of pheromone receptor activation in the mammalian brain
47. Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro
48. Semaphorin 3A is a chemoattractant for cortical apical dendrites
49. EphB receptors interact with NMDA receptors and regulate excitatory synapse formation
50. EphB/syndecan-2 signaling in dendritic spine morphogenesis
51. Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins
52. Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation
53. Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway
54. An ephrin-A-dependent signaling pathway controls integrin function and is linked to the tyrosine phosphorylation of a 120 kDa protein
55. Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner
56. Regulation of cell motility by mitogen-activated protein kinase
57. Rho GTPases in growth cone guidance
58. Rho family GTP-binding proteins in growth cone signalling
59. Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase
60. EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin
61. Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons
62. Novel expression gradients of Eph-like receptor tyrosine kinases in the developing chick retina