EphB receptors interact with NMDA receptors and regulate excitatory synapse formation

Cell

Volumn 103, Issue 6, 2000, Pages 945-956

  Dalva, Matthew B ^a   Takasu, Mari A ^a   Lin, Michael Z ^a   Shamah, Steven M ^a   Hu, Linda ^a   Gale, Nicholas W ^b   Greenberg, Michael E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN TYROSINE KINASE; RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SPECIFICITY; CELL SURFACE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT; SYNAPSE;

ANIMALIA;

EID: 0033635736     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)00197-5     Document Type: Article

References (46)

1. Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina
2. A synaptic model of memory: Long-term potentiation in the hippocampus
3. Signaling by Eph receptors and their ephrin ligands
4. Tyrosine phosphorylation of transmembrane ligands for Eph receptors
5. The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain
6. Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
7. Monitoring secretory membrane with FM1-43 fluorescence
8. The distribution of glutamate receptors in cultured rat hippocampal neurons: Postsynaptic clustering of AMPA-selective subunits
9. Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
10. The ephrins and Eph receptors in neural development
11. Assembly of new individual excitatory synapses: Time course and temporal order of synaptic molecule recruitment
12. Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis
13. Calcium/calmodulin-dependent protein kinase II is associated with NR2A/B subunits of NMDA receptor in postsynaptic densities
14. PDZ domains in synapse assembly and signalling
15. Agrin acts via a MuSK receptor complex
16. Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling
17. Nuk controls pathfinding of commissural axons in the mammalian central nervous system
18. Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
19. Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta
20. Cloned glutamate receptors
21. Synaptic activity and the construction of cortical circuits
22. Activity-dependent regulation of synaptic clustering in a hippocampal culture system
23. Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor
24. Formation of functional synaptic connections between cultured cortical neurons from agrin-deficient mice
25. Persistent protein kinase activity underlying long-term potentiation
26. Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo
27. The development of excitatory synapses in cultured spinal neurons
28. Molecular mechanisms of glutamate receptor clustering at excitatory synapses
29. Identification of a phosphorylation site for calcium/calmodulindependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptor
30. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation
31. Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture
32. The kinetics of synaptic vesicle recycling measured at single presynaptic boutons
33. Development of the vertebrate neuromuscular junction
34. Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
35. Intracellular signaling path-ways activated by neurotrophic factors
36. Synapse formation by hippocampal neurons from agrin-deficient mice
37. The c-fins proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1
38. Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells
39. The synaptic vesicle cycle: A cascade of protein-protein interactions
40. Regulation of ligand-gated ion channels by protein phosphorylation
41. PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands
42. Signal transduction by receptors with tyrosine kinase activity
43. Receptor tyrosine kinase specific for the skeletal muscle lineage: Expression in embryonic muscle, at the neuromuscular junction, and after injury
44. Fine structure of synaptogenesis in the vertebrate central nervous system
45. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism
46. Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-D-aspartate receptors