TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell destruction

Diabetologia

Volumn 45, Issue 12, 2002, Pages 1678-1688

  Ou, Dawei ^a   Metzger, D L ^a   Wang, X ^a   Huang, J ^a   Pozzilli, P ^b   Tingle, A J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; Cytotoxicity; Pancreatic beta cells; TRAIL; Type I diabetes

Indexed keywords

ALPHA 1 BETA 2 LYMPHOTOXIN; ALPHA 2 BETA 1 LYMPHOTOXIN; CD4 ANTIGEN; CD8 ANTIGEN; CHROMIUM 51; CYCLOHEXIMIDE; CYTOKINE; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS LIGAND; LIPOCORTIN 5; LYMPHOTOXIN; PROTEIN SYNTHESIS INHIBITOR; RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 3; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 4; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; MEMBRANE PROTEIN; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR;

APOPTOSIS; ARTICLE; CELL DESTRUCTION; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; CELL CLONE; CELL CULTURE; CELL DEATH; CULTURE MEDIUM; CYTOTOXIC T LYMPHOCYTE; DRUG EFFECT; DRUG RESISTANCE; METABOLISM; PANCREAS ISLET; PHYSIOLOGY;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL DEATH; CELLS, CULTURED; CLONE CELLS; CULTURE MEDIA; CYTOKINES; DRUG RESISTANCE; HUMANS; ISLETS OF LANGERHANS; MEMBRANE GLYCOPROTEINS; RECEPTORS, TUMOR NECROSIS FACTOR; T-LYMPHOCYTES, CYTOTOXIC; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036460328     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0926-2     Document Type: Article

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