Apoptosis and autoimmune thyroid disease: Following a TRAIL to thyroid destruction?

Clinical Endocrinology

Volumn 55, Issue 1, 2001, Pages 1-11

  Bretz, James D ^a   Baker Jr , James R ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 8; CYCLOHEXIMIDE; CYTOKERATIN 18; DNA FRAGMENT; FAS LIGAND; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 1BETA; PERFORIN; PROTEIN BCL 2; PROTEIN P53; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; AUTOIMMUNITY; CYTOTOXICITY; DISEASE COURSE; EFFECTOR CELL; ENZYME ACTIVATION; HASHIMOTO DISEASE; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REVIEW; THYROID CELL; THYROID GLAND; THYROIDITIS;

ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; FAS LIGAND PROTEIN; HUMANS; LIGANDS; MEMBRANE GLYCOPROTEINS; MODELS, IMMUNOLOGICAL; THYROIDITIS, AUTOIMMUNE; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035725796     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2001.01345.x     Document Type: Review

References (92)

1. The Bcl-2 protein family: Arbiters of cell survival
2. Cytokines and thyroid function
3. Experimental autoimmune thyroiditis (EAT) in mice lacking the IFN-gamma receptor gene
4. The domains of death: Evolution of the apoptosis machinery
5. Fas (APO-1, CD95) -mediated apoptosis in thyroid cells is regulated by a labile protein inhibitor
6. Fas (CD95) expression is up-regulated on papillary thyroid carcinoma
7. Apoptosis control by death and decoy receptors
8. Immunologic aspects of endocrine diseases
9. Specificity questions concerning the clone 33 anti-fas ligand antibody
10. Modulation of life and death by the TNF receptor superfamily
11. Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis
12. Gene therapy of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for Fas ligand
13. Bcl-2 proto-oncogene expression in neoplastic and non neoplastic thyroid tissue
14. TRAIL death pathway expression and induction in thyroid follicular cells
15. Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells
16. Role of Apoptosis in Auto-immune Thyroid Disease
17. Cell population kinetics in dog and human adult thyroid
18. The lpr and gld genes in systemic autoimmunity: Life and death in the Fas lane
19. What is meant today by Hashimoto's thyroiditis?
20. Experimental autoimmune thyroiditis. In vitro cytotoxic effects of T lymphocytes on thyroid monolayers
21. A new classification for human autoimmune thyroid disease
22. Chronic autoimmune thyroiditis
23. FasL expression on epithelial cells: The Bottazzo-Feldman hypothesis revisited
24. IAP family proteins - Suppressors of apoptosis
25. Deficiency of the Fas apoptosis pathway without Fas gene mutations in pediatric patients with autoimmunity/ lymphoproliferation
26. Autoimmune diabetes: The involvement of benign and malignant autoimmunity
27. Apoptosis in dog thyroid cells
28. A receptor for phosphatidylserine-specific clearance of apoptotic cells
29. Antibody mAb33 from transduction laboratories detects human CD95L in ELISA but not in immuno-blots
30. Constitutive expression of FasL in thyrocytes
31. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
32. T-dependent destruction of thyroid isografts exposed to IFN-gamma
33. CD40 stimulation inhibits cell growth and Fas-mediated apoptosis in a thyroid cancer cell line
34. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
35. Characterization of autoimmune thyroiditis in MRL-lpr/lpr mice
36. Reduced cell-cell communication in a spontaneous murine model of autoimmune thyroid disease
37. Mitochondria and apoptosis
38. Analysis of apoptosis in relation to tissue destruction associated with Hashimoto's auto-immune thyroiditis
39. Kenntniss der lymphomatosen veranderung der schilddruse (Struma lymphomatosa)
40. Increased serum soluble Fas in patients with Graves' disease
41. Functional Fas ligand expression in thyrocytes from patients with Graves' disease
42. Inhibition of death receptor signals by cellular FLIP
43. Thyroid-stimulating hormone inhibits Fas antigen-mediated apoptosis of human thyrocytes in vitro
44. Modulation of Fas-mediated apoptosis of human thyroid epithelial cells by IgG from patients with Graves' disease (GD) and idiopathic myxoedema
45. Induction of experimental thyroiditis in mice by recombinant interferon gamma administration
46. CD4+ T cell-mediated cytotoxicity toward thyrocytes: The importance of Fas/ Fas ligand interaction inducing apoptosis of thyrocytes and the inhibitory effect of thyroid-stimulating hormone
47. Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity
48. Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis
49. Benign versus destructive insulitis
50. Apoptosis in thyroid tissue from patients with Hashimoto's thyroiditis
51. Intrathyroidal T cell clones from patients with autoimmune thyroid disease
52. Surface expression of TRAIL/ Apo-2 ligand in activated mouse T and B cells
53. Pathogenesis of thyroid autoimmunity: The Bottazzo-Feldmann hypothesis
54. Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis
55. Fas ligand expression in thyroid carcinomas: A potential mechanism of immune evasion
56. Fas ligand expression in thyroid follicular cells from patients with thionamide-treated Graves' disease
57. Thyroid carcinoma cells are resistant to fas-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand
58. The Bcl-2 family and cell death regulation
59. From bench to clinic with apoptosis-based therapeutic agents
60. Apoptosis in the effector phase of autoimmune diabetes, multiple sclerosis and thyroiditis
61. Enhanced cellular proliferative activity and cell death in chronic thyroiditis and thyroid papillary carcinoma
62. In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha
63. Death of the autoimmune thyrocyte: Is it pushed or does it jump?
64. Possible pathogenetic relevance of interleukin-1 beta in 'destructive' organ-specific autoimmune disease (Hashimoto's thyroiditis)
65. Constitutive expression of FasL in thyrocytes
66. Monokine-producing cells predominate in the recruitment phase of NOD insulitis while cells producing Th1-type cytokines characterize the effector phase
67. Double identity for proteins of the Bcl-2 family
68. Killer cell activity and antibody-dependent cell-mediated cytotoxicity are normal in Hashimoto's disease
69. Caspases: Intracellular signaling by proteolysis
70. FAP-1: A protein tyrosine phosphatase that associates with Fas
71. Corpse clearance defines the meaning of cell death
72. Iodide, cytokines and TSH-receptor expression in Graves' disease
73. Serum concentration of soluble Fas in patients with autoimmune thyroid diseases
74. Technical note: Aberrant detection of cell surface Fas ligand with anti-peptide antibodies
75. Fas/Fas ligand-driven T cell apoptosis as a consequence of ineffective thyroid immuno-privilege in Hashimoto's thyroiditis
76. Constitutive expression of FasL in thyrocytes
77. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
78. Apoptosis signaling
79. CD95 ligand (CD95L) immunohistochemistry: A critical study on 12 antibodies
80. Induction of granulomatous experimental autoimmune thyroiditis in mice with in vitro activated effector T cells and anti-IFN-gamma antibody
81. Granule-mediated killing: Pathways for granzyme B-initiated apoptosis
82. The effects of a monoclonal antibody to interferon-gamma on experimental autoimmune thyroiditis (EAT): Prevention of disease and decrease of EAT-specific T cells
83. Apoptosis in thyroid diseases: A histochemical study
84. Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: Evidence for genetic heterogeneity and gene interactions
85. Cleavage of caspase family members by granzyme B: A comparative study in vitro
86. Evidence that the immunosuppressive effects of antithyroid drugs are mediated through actions on the thyroid cell, modulating thyrocyte-immunocyte signaling: A review
87. Expression of TRAIL receptors in human autoreactive and foreign antigen-specific T cells
88. Autoimmunity
89. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
90. Cell death: The significance of apoptosis
91. Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells