Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions

European Journal of Cancer

Volumn 34, Issue 9, 1998, Pages 1448-1454

  Weissleder, R ^a   Cheng, H C ^a   Marecos, E ^a   Kwong, K ^a   Bogdanov Jr , A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Angiogenesis; MR imaging; Neovascularity; Tumour; Vascular architecture

Indexed keywords

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; FEMALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; TUMOR GROWTH; TUMOR VASCULARIZATION;

ANIMALS; BRAIN NEOPLASMS; CAPILLARY PERMEABILITY; CONTRAST MEDIA; FEMALE; GADOLINIUM DTPA; GLIOMA; MAGNETIC RESONANCE SPECTROSCOPY; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; RATS;

EID: 0032145497     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(98)00195-6     Document Type: Article

References (40)

1. 1. Jain R. Determinants of tumor blood flow; a review. Cancer Res 1988, 48, 2641-2658.
2. 2. Zou Y, Ling YH, Reddy S, Priebe W, Perez-Soler R. Effect of vesicle size and lipid composition on the in vivo tumor selectivity and toxicity of the non-cross-resistant anthracycline annamycin incorporated in liposomes. Intern J Cancer 1995, 61, 666-671.
3. 3. Yuan F, Dellian M, Fukumura D, et al. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res 1995, 55, 3752-3756.
4. 4. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 1991, 324, 1-8.
5. 5. Weidner N, Folkman J, Pozza F, et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Canc Inst 1992, 84, 1875-1887.
6. 6. Weidner N, Carroll PR, Flax J, Blumenfeld W, Folkman J. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 1993, 143, 401-409.
7. 7. Hilmas D, Gillette E. Morphometric analysis of the microvasculature of tumors during growth and after irradiation. Cancer 1974, 33, 103-110.
8. 8. Jain R. Vascular and interstitial barriers to delivery of therapeutic agents in tumors. Cancer and Metast Rev 1990, 9, 253-266.
9. 9. Evelhoch JL. Measurement of tumor blood flow by deuterium NMR and the effects of modifiers. NMR Biomedicine 1992, 5, 290-295.
10. 19F magnetic resonance imaging. Invest Radiol 1993, 28, 710-719.
11. 11. Su MY, Jao JC, Nalcioglu O. Measurement of vascular volume fraction and blood-tissue permeability constants with a pharmacokinetic model: studies in rat muscle tumors with dynamic Gd-DTPA enhanced MRI. Magn Reson Med 1994, 32, 714-724.
12. 12. Brasch R, Pham C, Shames D, et al. Assessing tumor angiogenesis using macromolecular MR imaging contrast media. J Mag Res Imaging 1997, 7, 68-74.
13. 13. Bogdanov AA, Weissleder R, Frank HW, et al. A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology 1993, 187, 701-706.
14. 14. Callahan R, Bogdanov A, Fischman A, Brady T, Weissleder R. Pre-clinical evaluation and phase I clinical trial of a synthetic polymer contrast agent for blood pool imaging. Am J Roent 1998, in press.
15. 15. Donahue KM, Weisskoff RM, Chesler D, et al. Improving MR quantification of regional blood volume with intravascular T1 contrast agents: accuracy, precision, and water exchange. Magn Res Med 1997, 36, 859-867.
16. 16. Callahan R, Wilkinson R, Bogdanov Jr. A, Donahue K, Weissleder R, Fischman A. Validation of plasma volume determinations in the rat using an In-111 labeled polymer and I-125 human serum albumin. 42nd Annual Meeting of the Society of Nuclear Medicine, Minneapolis, Minnesota. Society of Nuclear Medicine, 1995, 157.
17. 17. Donahue K, Weisskoff R, Parmelee D, et al. Dynamic Gd-DTPA enhanced MRI measurement of tissue cell volume fraction. Magn Reson Med 1995, 34, 423-432.
18. 18. Brasch R. Contrast-enhanced magnetic resonance imaging: why and how? In Brasch R, Drayer BP, Haughton VM, Jinkins JR, Nelson KL, Sze G, eds. MRI contrast enhancement in the central nervous system. New York, Raven Press, 1993, 1-10.
19. 19. Reed R, Lepose S, Wiig H. Interstitial exclusion of albumin in rat dermis and subcutis in over-and dehydration. Am J Physiol 1989, 257, H1819-H1827.
20. 20. Roberts T. Physiologic measurements by contrast-enhanced MR imaging: expectations and limitations. J Mag Res Imaging 1997, 7, 82-90.
21. 21. Su MY, Najafi AA, Nalcioglu O. Regional comparison of tumor vascularity and permeability parameters measured by albumin-Gd-DTPA and Gd-DTPA. Magn Reson Med 1995, 34, 402-411.
22. 22. Kovar D, Lewis M, River J, Lipton M, Karczmar G. In vivo imaging of extraction fraction of low molecular weight MR contrast agents and perfusion rate in rodent tumors. Magn Reson Med 1997, 38, 259-268.
23. 23. Ritschel W. Handbook of basic pharmacokinetics: including clinical applications, 3rd edition. Drug Intelligence Publication Inc., Hamilton, Illinois, 1986.
24. 24. Shames DM, Kuwatsuru R, Vexler V, Muhler A, Brasch RC. Measurement of capillary permeability to macromolecules by dynamic magnetic resonance imaging: a quantitative noninvasive technique. Magn Reson Med 1993, 29, 616-622.
25. 25. Buxton RB, Frank LR, Prasad PV. Principles of diffusion and perfusion MRI. In Edelman RR, ed. Clinical Magnetic Resonance Imaging. Philadelphia, WB Saunders, 1996, 233-270.
26. 26. Kennan RP, Zhong J, Gore JC. On the relative importance of paramagnetic relaxation and diffusion-mediated susceptibility losses in tissues. Magn Reson Med 1991, 22, 197-203.
27. 27. Finn J, Simonetti O. Pulse sequence design in MRI. In Edelman RR, Hesselink JR, Zlatkin MB, eds. Clinical Magnetic Resonance Imaging. Philadelphia, WB Saunders, 1996, 145-176.
28. 28. Hendrick RE, Haacke EM. Basic physics of MR contrast agents and maximization of image contrast. J Mag Res Imaging 1993, 3, 137-148.
29. 29. Aukland K, Reed R. Interstitial-lymphatic mechanisms in the control of extracellular fluid volume. Physiological Reviews 1993, 73, 1-78.
30. 30. Gullino P, Grantham F. The interstitial water space of tumors. Canc Res 1965, 25, 727-731.
31. 31. Fallowfield M. Vascular volume in B16 allografts and human melanoma xenografts estimated by means of Hoechst 33342. J Pathol 1989, 157, 249-252.
32. 32. Jain RK. Delivery of noval therapeutic agents in tumors: physiological barriers and strategies. J Nat Cancer Inst 1989, 81, 570-576.
33. 33. Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK. Vascular permeability and microcirculation of glioma and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res 1994, 54, 4564-4568.
34. 34. Bernsen H, Rijken P, Oostendorp T, van der Kogel A. Vascularity and perfusion of human gliomas xenografted in the athymic nude mouse. Br J Cancer 1995, 71, 721-726.
35. 35. Tofts PS, Kermode AG. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Magn Reson Med Fundamental concepts. 1991, 17, 357-367.
36. 36. Kuwatsuru R, Shames DM, Muhler A, et al. Quantification of tissue plasma volume in the rat by contrast-enhanced magnetic resonance imaging. Magn Reson Med 1993, 30, 76-81.
37. 37. Bauer WR, Hiller KH, Roder F, Rommedl E, Ertl G, Haase A. Magnetization exchange in capillaries by microcirculation affects diffusion-controlled spin-relaxation: a model which describes the effect of perfusion on relaxation enhancement by intravascular contrast agents. Magn Reson Med 1996, 35, 43-55.
38. 38. Mayo-Smith W, Saini S, Slater G, Kaufman J, Sharma P, Hahn P. MR contrast material for vascular enhancement: value of superparamagnetic iron oxide. Am J Roent 1996, 166, 73-77.
39. 39. Barnett PA, Roman-Goldstein A, Ramsey F, et al. Differential permeability and quantitative MR imaging of a human lung carcinoma brain xenograft in the nude rat. Am J Pathol 1995, 146, 436-449.
40. 40. Abramovitch R, Meir G, Neeman M. Neovascularization induced growth of implanted C6 glioma multicellular spheroids: magnetic resonance microimaging. Cancer Res 1995, 55, 1956-1962.