Localization of idine-125-mIP-Des-Met14bmbesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer

Journal of Nuclear Medicine

Volumn 38, Issue 8, 1997, Pages 1221-1229

  Rogers, Buck E ^a   Rosenfeld, Maryland E ^a   Khazaeli, M B ^a   Mikheeva, Galina ^a   Stackhouse, Murray A ^a   Liu, Tiepu ^a   Curiel, David T ^a   Buchsbaum, Donald J ^a  

^a The University of Alabama at Birmingham   (United States)

Author keywords

Adenovirus; Bombesin; Gastrin releasing peptide receptor; Gene transfer; Iodine 125

Indexed keywords

BOMBESIN DERIVATIVE; BOMBESIN[4 TYROSINE]; GASTRIN RELEASING PEPTIDE; IODINE 125; RECEPTOR PROTEIN; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE TRANSFER; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; RADIATION DOSE; RADIOACTIVITY; RECEPTOR UPREGULATION; TUMOR LOCALIZATION;

ADENOVIRIDAE; ANIMALS; BOMBESIN; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; IODINE RADIOISOTOPES; MICE; MICE, INBRED BALB C; MICE, NUDE; OVARIAN NEOPLASMS; PEPTIDE FRAGMENTS; RECEPTORS, BOMBESIN; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 0030873487     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Goldenberg DM. New developments in monoclonal antibodies for cancer detection and therapy. CA-Cancer J Clin 1994:44:43-64.
2. Jurcic JG. Scheinberg DA. Radioimmunotherapy of hematological cancer: problems and progress. Clin Cancer Res 1995;1:1439-1446.
3. Buchsbaum D.I. Expérimental radioimmunotherapy and methods to increase therapeutic efficacy. In: Goldenberg, D. M., ed. Cancer therapy with radiolabe led antibodies. Boca Raton, FL: CRC Press; 1995:115 140.
4. Hand PH. Robbins PF, Salgaller ML, Poole D.I, Schlom J. Evaluation of human carcinoembryonic-antigen (CEA)-transduced and non-transduced murine tumors as potential targets for anti-CEA therapies. Cancer Immunol Immunolher 1993:36:65-75.
5. Raben D. Buchsbaum DJ, Khazaeli MB, et al. Enhancement of radiolabeled antibody binding and tumor localization through adenoviral transduction of the human carcinoembryonic antigen gene. Gene Ther 1996;3:567-580.
6. Buchsbaum DJ. Raben D. Stackhoüse MA, et al. Approaches to enhance cancer radiotherapy employing gene transfer methods. Gene Ther 1996:3:1042-1068.
7. Falck-Pedersen E, Heinflink M, Alvira M, Nussenzveig DR, Gershengorn MC. l-4xpression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific. Mol Pharmacol 1994;45:6H4-689.
8. Hinuma S, Hosoya M, Ogi K, et al. Molecular cloning and functional expression of a human thyrotropin-releasing hormone (TRH) receptor gene. Biochim Biophvs Ada 1994:1219:251 259.
9. Raben D, Buchsbaum DJ, Khazaeli MB, et al. Strategies to augment radioimmunotherapy via genetic induction of receptors for radioligand binding. Cancer Gene Ther 1995:2:330.
10. Moody TW, Cuttitta F. Growth factor and peptide receptors in small cell lung cancer. Life Sei 1993:52:1161-1173.
11. Yu D, Wolf .IK, Scanlon M, Price JE, Hung MC. Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by El A. Cancer Res 1993:53:891 898.
12. Deshane J, Siegal GP, Alvarez RD, et al. Targeted tumor killing via an intracellular antibody against erbB-2../ Clin Invest 1995:96:2980 2989.
13. Hoffman TJ, Sieckman GL, Volkert WA. Targeting small cell lung cancer using iodinated peptide analogs. J Labeled Compd Radiophwm 1995:37:321 323.
14. Huffman TJ. Sieckman GL, Volkert WA. Iodinated bombesin analogs: effect of N-terminal versus side chain iodine attachment on BBN/GRP receptor binding../ Nucl Med 1996;37:185P.
15. Ning L, Huffman TJ, Sieckman GL, et al. In vitro and in vivo characterization of a Rh-105-tetrathiamaerocycle conjugate of a bombesin analog../ Nucl Med 1996:37:61 P.
16. Zalutsky MR, Narula AS. A method for the radiohalogcnation ot proteins resulting in decreased thyroid uptake of radioiodine. Appl Radial hoi 1987:38:1051 1055.
17. Battey JF, Way JM, Corjay MH, et al. Molecular cloning of the bombesin/gastrmreleasing peptide receptor from Swiss 3T3 cells, /'roc Null Acad Sei USA 1991;88: 395-399.
18. Geissler F, Anderson SK, Venkatesan P. Press C). Intracellular catabolism of radiolabeled anti-/j, antibodies by malignant B-cclls. Cancer Res 1992:52:2907 2915.
19. Becker TC, Noel R.I, Coats WS, et al. Use of recombinant adenovirus for metabolic engineering of mammalian cells. Method Cell Biol 1994:43:161 189.
20. Rosenfeld MF Rogers BE, Khazaeli MB. et al. Adenoviral mediated delivery of gastrin releasing peptide receptor results in specific tumor locali/ation of a bombesin analog in vivo. Clin Cancer Rex 1997;3:1 187-1194.
21. Snedecor GW, Cochran WG. Statistical methods. 7th éd. Ames, I A: The Iowa StateUniversity Press; 1980.
22. Liu T. Characteristics of pharmacokinetics modeling in a phase I clinical trial of radiolabeled monoclonal antibody. Controlled Clin Trials 1991:12:654-655.
23. Rogers BE, Stackhouse M, Khazaeli MB, et al. Evaluation of a radioiodinaled bombesin analog as a potential radiotherapeutic agent../ Nucl Med 1996:37:186P.
24. Zhu WY, Gokc B, Williams JA. Binding, internalization and processing of bombesin by rat pancreatic acini. Am J Physiol 1991;261:G57 G64.
25. Garg PK, Alston KL, Welsh PC, Zalutsky MR. Enhanced binding and inertness to dehalogenation of -melanolropic peptides labeled using N-succinimidyl 3-iodobenzoate. Bioconjugale Chem 1996:7:233-239.
26. Press OW. Shan D, Howell-Clark J, et al. Comparative metabolism and retention of iodine-125, yttrium-90 and indium-Ill radioimmunoconjugates by cancer cells. Cancer Res 1996:56:2123 2129.
27. Zalutsky MR, Noska MA, C'olapinto EV. Garg PK. Bigner DD. Enhanced tumor localization and in vivo stability of a monoclonal antibody radioiodinated using N-succinimidyl 3-(tri-n-butylstannyl)benzoate. Cancer Res 1989:49:5543 5549.
28. Rowlinson G, Snook D. Busza A. Epenetos AA. Antibody-guided localization of intraperitoneal tumors following intraperiloneal or intravenous antibody administration. Cancer Res 1987:47:6528-4 6531.
29. Ward BG, Mather SJ, Hawkins LR, et al. Localization of radioiodine conjugated to the monoclonal antibody HMFG2 in human ovarian carcinoma: assessment of intravenous and intraperitoneal routes of administration. Cancer Res 1987:47:4719 4723.
30. Brody SL. Jaffe A, Man SK. Wcrsto RP, Crystal RG. Direct in vivo gene transfer and expression in malignant cells using adenovirus vectors. Hum Gene Ther 1994:5:437 447.
31. Smythe WR, Kaiser LR, Hwang HC, et al. Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma. Ann Thorac Surg 1994:57:1395 1401.
32. Wills KN, Maneval DC. Menzel P. et al. Development and characteri/ation of recombinant adenoviruses encoding human p53 lor gene therapy of cancer. Hum Gene Ther 1994;5:1079- 1088.
33. Cusack JC, Spitz FR, Nguyen D, et al. High levels of gene transduction in human lung tumors following intralesional injection of recombinant adenovirus. Cancer Gene Ther 1996;3:245 249.
34. Douglas JT. Rogers BE, Rosenfeld ME, et al. Targeted gene delivery by tropismmodified adenoviral vectors. Nat Biotechnol 1996:14:1574 1578.
35. Garver Rl, Jr. Goldsmith KT, Rodu B. et al. Strategy for achieving selective killing of carcinomas. Gene Ther 1994:1:46-50.
36. Smith MJ, Rousculp MD, Goldsmith KT, Curiel DT, Garver Rl Jr. Surfactant protein A-directed toxin gene kills lung cancer cells in vitro. Hum Gene Ther 1994:5:29 35.
37. Tanaka T, Kanai F, Okabe S, et al. Adenovirus-mediated prodrug gene therapy lor carcinoembryonic antigen-producing human gastric carcinoma cells in vitro. Cancer Res 1996:56:1341-1345.