Development of beta3-adrenoceptor agonists for the treatment of obesity and diabetes - An update

Diabetes and Metabolism

Volumn 25, Issue 1, 1999, Pages 11-21

  Weyer, C ^a   Gautier, J F ^a   Danforth Jr , E ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b National Institutes of Health ^*

Author keywords

3 adrenoreceptor; 3 adrenoreceptor agonist; Brown adipose tissue; Obesity; Treatment; Type 2 diabetes

Indexed keywords

4 [2 [(2 HYDROXY 2 PHENYLETHYL)AMINO]PROPYL]BENZOIC ACID METHYL ESTER; 4 [2 [(2 HYDROXY 2 PHENYLETHYL)AMINO]PROPYL]BENZOIC ACID METHYL ESTER HYDROGEN MALEATE; 4 [2 [(2 HYDROXY 3 PHENOXYPROPYL)AMINO]ETHOXY] N (2 METHOXYETHYL)PHENOXYACETAMIDE; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID METHYL ESTER; 5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; ANTIDIABETIC AGENT; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; RO 402148; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; BETA ADRENERGIC STIMULATION; DIABETES MELLITUS; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG EFFICACY; DRUG INDUSTRY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; FATTY ACID OXIDATION; HUMAN; INSULIN SENSITIVITY; LIPOLYSIS; MOUSE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; RAT; REVIEW; THERMOGENESIS; WHITE ADIPOSE TISSUE;

ADRENERGIC BETA-AGONISTS; ANIMALS; ANTI-OBESITY AGENTS; DIABETES MELLITUS; DIABETES MELLITUS, TYPE 2; DIOXOLES; DRUG DESIGN; HUMANS; HYPOGLYCEMIC AGENTS; OBESITY; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-3;

EID: 0032923340     PISSN: 03381684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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