Plant α-amylase inhibitors and their interaction with insect α-amylases: Structure, function and potential for crop protection

European Journal of Biochemistry

Volumn 269, Issue 2, 2002, Pages 397-412

  Franco, Octávio L ^a,b,c   Rigden, Daniel J ^a   Melo, Francislete R ^a,c   Grossi de Sá, Maria F ^a  

^a EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA   (Brazil)

^b UNIVERSIDADE CATÓLICA DE BRASÍLIA   (Brazil)

^c Depto de Biologia Celular   (Brazil)

Author keywords

amylase inhibitors; Bean weevils; Bifunctional inhibitors; Cereal type; Knottin like; Kunitz; Lectin like; Thaumatin like

Indexed keywords

ACARBOSE; AMYLASE; AMYLASE INHIBITOR; APROTININ; CYCLODEXTRIN; LECTIN; THAUMATIN;

CROP PROTECTION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STRUCTURE; NONHUMAN; PEST CONTROL; PRIORITY JOURNAL; REVIEW; TRANSGENIC PLANT;

ALPHA-AMYLASE; ANIMALS; ENZYME INHIBITORS; INSECTS; PLANTS;

ACANTHOSCELIDES OBTECTUS; CURCULIONIDAE; FUNGI; HEXAPODA; INSECTA; PHASEOLUS (ANGIOSPERM);

EID: 0036164521     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0014-2956.2001.02656.x     Document Type: Review

References (160)

1. Potential of plant-derived genes in the genetic manipulation of crops for insect resistance
2. Insect-resistant transgenic plants
3. A novel mechanism of insect resistance engineered into tobacco
4. Butterflies and plants: A study in co-evolution
5. Protease inhibitors in plants: Genes for improving defenses against insects and pathogens
6. Systemin: A polypeptide signal for plant defensive genes
7. Rapid evolution in plant chitinases: Molecular targets of selection in plant-pathogen co-evolution
8. Do legumes storage proteins play a role in defending seeds against bruchids?
9. Interaction of insect digestive enzymes with plant protein inhibitors and host-parasite co-evolution
10. Genetic engineering with α-amylase inhibitors seeds resistant to bruchids
11. Identifying proteins with insecticidal activity: Use of encoding genes to produce insect-resistant transgenic crops
12. Growth inhibitory effects of an α-amylase inhibitor from kidney bean, Phaseolus vulgaris (L.) on three species of bruchids (Coleoptera: Bruchidae)
13. Transgenic pea seeds expressing the α-amylase inhibitor of the common bean are resistant to bruchid beetles
14. Digestion in larvae of Callosobruchus maculatus and Zabrotes subfasciatus (Coleoptera: Bruchidae) with emphasis on α-amylases and oligosaccaridases
15. Apocrine secretion of amylase and exocytosis of trypsin along the midgut of Tenebrio molitor larvae
16. Resolution and partial characterization of proteinases and α-amylases from midguts of larvae of the bruchid beetle Callosobruchus maculatus (F.)
17. Molecular cloning of bruchid (Zabrotes subfasciatus) α-amylase cDNA and interactions of the expressed enzyme with bean amylase inhibitors
18. cDNA cloning, biochemical characterization and inhibition by plant inhibitors of the α-amylases of the Western corn rootworm, Diabrotica virgifera virgifera
19. Interaction of Tenebrio molitor L. α-amylase with wheat flour protein inhibitor
20. Crystal structure of yellow mealworm α-amylase at 1.64 Å resolution
21. Crystal structure of calcium-depleted Bacillus licheniformis α-amylase at 2.2 Å resolution
22. Metal content of α-amylases of various origins
23. Carbohydrate binding site in a pancreatic α-amylase-substrate complex, derived from X-ray structure analysis at 2.1 Å resolution
24. Crystal structure of thermostable α-amylase from Bacillus licheniformis refined at 1.7 Å resolution
25. The catalytic mechanism of α-amylases based upon enzyme crystal structures and model binding calculations
26. Protein engineering in the α-amylase family: Catalytic mechanism, substrate specificity and stability
27. Relationship of sequence and structure to specificity in the α-amylase family of enzymes
28. Carbohydrate and protein-based inhibitors of porcine pancreatic α-amylase: Structure analysis and comparison of their binding characteristics
29. Comparative study of the inhibition of α-glucosidase, α-amylase, and cyclomaltodextrin glucanosyltransferase by acarbose, isoacarbose, and acarviosine-glucose
30. α-amylase inhibitors from Roselle (Hibiscus sabdariffa Linn.) tea
31. Crystal structures of human pancreatic α-amylase in complex with carbohydrate and proteinaceous inhibitors
32. Enzyme-catalyzed condensation reaction in a mammalian alpha-amylase. High resolution structural analysis of an enzyme inhibitor complex
33. Refined molecular structure of pig pancreatic α-amylase at 2.1 Å resolution
34. Kinetic studies on the hydrolases of α-, β- and γ-cyclodextrins by Taka-amylase A
35. Crystal structure of Termo-actynomices vulgaris R.-47 α-amylase II (TVA II) hydrolyzing cyclodextrins and Pullulan at 2.6 Å resolution
36. In vitro action of human and porcine α-amylase on cyclomalto-oligosaccharides
37. Mechanism of porcine pancreatic α-amylase. Inhibition of amylose and maltopentaose hydrolysis by α-, β- and γ-cyclodextrins
38. Mechanism of porcine pancreatic α-amylase. Inhibition of amylose and maltopentaose hydrolysis by kidney bean (Phaseolus vulgaris) inhibitor and comparison with that by acarbose
39. Crystal structure of pig pancreatic α-amylase isoenzyme II, in complex with the carbohydrate inhibitor acarbose
40. Some aspects of the mechanism of complexation of red kidney bean α-amylase inhibitor and α-amylase
41. Molecular structure of a barley α-amylase inhibitor complex: Implications for starch binding and catalysis
42. Catalytic mechanisms of enzymatic glycosyl transfer
43. Acarbose-ein neues wirkprinzip in der diabetes-therapie
44. Differential serum amylase determination by use of an inhibitor and design of a routine procedure
45. α-amylase inhibitors
46. Activity of wheat α-amylase inhibitors towards bruchid α-amylases and structural explanation of observed specificities
47. Purification, biochemical characterisation and partial primary structure of a new α-amylase inhibitor from Secale cereale (Rye)
48. Further characterization studies of the alpha-amylase protein inhibitor of gel eletrophoretic mobility 0.19 from the wheat kernel
49. α-amylase inhibitors from wheat: A sequences and patterns of inhibition of insect and human α-amylases
50. Arginine is essential for the α-amylase inhibitory activity of the α-amylase/subtilisin inhibitor (BASI) from barley seeds
51. A new family of small (5 kD) protein inhibitors of insect α-amylase from seeds of sorghum (Sorghum bicolor (L.) Moench) have sequence homologies with wheat δ-purothionins
52. Rye inhibitors of animal α-amylases shown different specificities, aggregative properties and IgE-binding capacities than their homologues from wheat and barley
53. Rice bifunctional α-amylase/subtilisin inhibitor: Characterization, localization, and changes in developing and germinating seeds
54. Amylase inhibitors of pigeonpea (Cajanus cajan) seeds
55. α-amylase from cowpea seeds
56. Molecular characterization of a bean α-amylase inhibitor that inhibits the α-amylase of the Mexican bean weevil Zabrotes subfasciatus
57. Post-translational processing of two α-amylase inhibitors and an arcelin from the common bean, Phaseolus vulgaris
58. Complete sequence, subunit structure and complexes with pancreatic α-amylase of an α-amylase inhibitor from Phaseolus vulgaris white kidney beans
59. Seed storage proteins: The enzyme inhibitors
60. Purification and properties of phaseolamin, an inhibitor of α-amylase, from the kidney bean, Phaseolus vulgaris
61. Characterization of two amylase inhibitors from black bean (Phaseolus vulgaris)
62. Characterization and functional properties of the α-amylase inhibitor (α-AI) from kidney bean (Phaseolus vulgaris) seeds
63. A lectin gene encodes the α-amylase inhibitor of the common bean
64. Isolation and characterization of the subunits of a heat labile α-amylase inhibitor from Phaseolus vulgaris white kidney bean
65. C-Terminal post-translational proteolysis of plant lectins and their recombinant forms expressed in Escherichia coli. Characterization of 'ragged ends' by mass spectrometry
66. Structural characterization of an α-amylase inhibitor from a wild common bean (Phaseolus vulgaris): Insight into the common structural features of leguminous α-amylase inhibitors
67. Activation of bean (Phaseolus vulgaris) α-amylase inhibitor requires proteolytic processing of the pro-protein
68. A putative precursor protein in the evolution of the bean alpha-amylase inhibitor
69. Insecticidal activity of an α-amylase inhibitor-like protein resembling a putative precursor of α-amylase inhibitor in the common bean, Phaseolus vulgaris L.
70. Inhibition of growth of Aspergillus flavus and fungal alpha-amylases by a lectin-like protein
71. Substrate mimicry in the active centre of a mammalian α-amylase: Structural analysis of an enzyme inhibitor complex
72. A plant-seed inhibitor of two classes of alpha-amylases: X-ray analysis of Tenebrio molitor larvae alpha-amylase in complex with the bean Phaseolus vulgaris inhibitor
73. Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans
74. A new rapid immuno-inhibition pancreatic amylase assay: Diagnostic value for pancreatitis
75. Bean α-amylase inhibitor confers resistance to the pea weevil, Bruchus pisorum, in genetically engineered peas (Pisum sativum L.)
76. Bean alpha-amylase inhibitor 1 in transgenic peas (Pisum sativum) provides complete protection from pea weevil (Bruchus pisorum) under field conditions
77. A novel α-amylase inhibitor from Amaranth (Amaranthus hypocondriacus) seeds
78. Solution structure of the major α-amylase inhibitor of the crop plant amaranth
79. Solution structure of the main α-amylase inhibitor from amaranth seeds
80. The refined 2.0 Å X-ray crystal structure of the complex formed between bovine b-trypsin and CMTI-I, a trypsin inhibitor from squash seeds (Cucurbita maxima). Topological similarity of the squash seed inhibitors with the carboxypeptidase A inhibitor from potatoes
81. Mapping function to structure in a channel-blocking peptide: Electrostatic mutants of charybdotoxin
82. Specific inhibition of insect α-amylases: Yellow meal worm α-amylase in complex with the Amaranth α-amylase inhibitor at 2.0 Å resolution
83. Wheat protein inhibitors of α-amylase
84. Characterization of homologous inhibitors of trypsin and α-amylase
85. Role of complex asparagine-linked glycans in the allergenicity of plant glycoproteins
86. CM-3, one of the wheat α-amylase inhibitor subunits, and binding of IgE in sera from Japanese with atopic dermatitis related to wheat
87. A major baker's asthma allergen from rye flour is considerably more active than its barley counterpart
88. A novel strategy for inhibition of α-amylases: Yellow meal worm α-amylase in complex with the Ragi bifunctional inhibitor at 2.5 Å resolution
89. Substrate-inhibitor interactions in the kinetics of α-amylase inhibition by Ragi α-amylase/trypsin inhibitor (RATI) and its various N-terminal fragments
90. Complete amino acid sequence of an alpha-amylase inhibitor in wheat kernel
91. Tertiary and quaternary structures of 0.19 α-amylase inhibitor from wheat kernel determined by X-ray analysis at 2.06 Å resolution
92. Crystallization and preliminary X-ray diffraction studies of the α-amylase inhibitor coded 0.19 from wheat kernel
93. Stability and kinetics of a bifunctional amylase/trypsin inhibitor
94. Determination of the three dimensional structure of the bifunctional α-amylase/trypsin inhibitors from Ragi seeds by NMR spectroscopy
95. RBI, a one-domain α-amylase/trypsin inhibitor with completely independent binding sites
96. Cloning of cDNA and chromosomal location of genes encoding the three types of subunits of the wheat tetrameric inhibitor of insect α-amylases
97. New dimeric inhibitor of heterologous α-amylases encoded by a duplicated gene in the short arm of chromosome 3B of wheat (Triticum aestivum L.)
98. Arg-27, Arg-127 and Arg-155 in the β-trefoil protein barley α-amylase/subtilisin inhibitor are interface residues in the complex with barley α-amylase 2
99. Enzymatic oxidation of the bifunctional wheat inhibitor of subtilisin and endogenous α-amylase
100. The amino acid sequence of a 20-kDa bifunctional subtilisin/α-amylase inhibitor from grain of rice (Oryza sativa L.) seeds
101. Barley α-amylase/subtilisin inhibitor. Isolation and characterization
102. Barley α-amylase bound to its endogenous protein inhibitor BASI: Crystal structure of the complex at 1.9 Å resolution
103. The three-dimensional structure of the bifunctional proteinase K/α-amylase inhibitor from wheat (PK13) at 2.5 Å resolution
104. Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds
105. Structure of ricin B chain at 2.5 Å resolution
106. Trypsin/α-amylase inhibitors and thionins: Possible defense proteins from barley
107. Stopped-flow kinetic studies of the reaction of barley α-amylase/subtilisin inhibitor and the high pI barley α-amylase
108. A tobacco mosaic virus-induced tobacco protein is homologous to the swett-tasting protein thaumatin
109. A new family of plant antifungal proteins
110. The crystal structure of the antifungal protein zeamatin, a member of the thaumatin-like, PR-5 protein-family
111. Zeamatin, an antifungal protein from maize with membrane-permeabilizing activity
112. Purification and characterization of an α-amylases inhibitor from maize (Zea mays)
113. Zeamatin inhibits trypsin and α-amylase activities
114. Two antifungal thaumatin-like proteins from barley grain
115. Several thaumatin-like proteins bind to β-1,3-glucans
116. Anti-fungal activity of tobacco osmotin has specificity and involves plasma membrane permeabilization
117. Zeamatin, an antifungal protein
118. Complete amino acide sequence from g-thionins from maize (Zea mays L.) seeds
119. Fungal membrane responses induced by plant defensines and thionins
120. Primary structure of ω-hordothionin, a member of a novel family of thionins from barley endosperm, and its inhibition of protein synthesis in eukaryotic and prokaryotic cell-free systems
121. Defense proteins from seed of Cassia fistula include a lipid transfer protein homologue and a protease inhibitory plant defensin
122. H-NMR structure of an antifungal γ-thionin protein Siα1: Similarity to scorpion toxins
123. Alpha plus beta folds revisited: Some favoured motifs
124. 1H-NMR: A structural motif common to toxic arthropod proteins
125. Conformational homogeneity in molecular recognition by proteolytic enzymes
126. Structural basis of the endoproteinase-protein inhibitor interaction
127. α-amylase from three species of stored grain coleoptera and their inhibition by wheat and corn proteinaceous inhibitor
128. Structural determinants of the bifunctional corn Hageman factor inhibitor: X-ray crystal structure at 1.95 Å resolution
129. The corn inhibitor of activated Hageman factor: Purification and properties of two rcombinant forms of the protein
130. Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure of proteinase K at 1.5 Å resolution
131. Crystallization of the bifunctional proteinase/amylase inhibitor PKI-3 and of its complex with proteinase K
132. Purification and characterization of an insect α-amylase inhibitor/endochitinase from seeds of Job's Tears (Coix Lachryma-jobi)
133. Analysis of structural and physico-chemical parameters involved in the specificity of binding between α-amylase and their inhibitors
134. Specific inhibition of barley α-amylase 2 by barley α-amylase/subtilisin inhibitor depends on charge interaction and can be conferred to isozyme 1 by mutation
135. Molecular basis for the specific binding of different α-amylase inhibitors from Phaseolus vulgaris sedes to the active site of α-amylase
136. Improved activity and modulated action pattern obtained by random mutagenesis at the fourth beta-alpha loop involved in substrate binding to the catalytic (beta/alpha) 8-barrel domain of barley alpha-amylase 1
137. Amylase inhibitors in Phaseolus vulgaris bean
138. Protective mechanism of the Mexican bean weevil against high levels of α-amylase inhibitor in the common bean
139. Inheritance of functional genes in plants
140. Transgenic plants for insect resistance
141. Bruchid resistance of transgenic azuki bean expressing seed α-amylase inhibitor of common bean
142. The complete amino acid sequence of a major wheat protein inhibitor of α-amylase
143. Site-directed mutagenesis and expression in Escherichia coli of WMAI-1, a wheat monomeric inhibitor of insect α-amylase
144. Overexpression in E. coli of chemically synthesized gene for active 0.19 α-amylase inhibitor from wheat kernel
145. Expression of the insecticidal bean alpha-amylase inhibitor transgene has minimal detrimental effect on the nutritional value of peas fed to rats at 30% of the diet
146. Food safety and quality for the consumer: Policies and communication
147. Assessing and structuring attitudes towards the use of gene technology in food production: The role of perceived ethical obligation
148. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
149. α-amylases of the coffee berry borer (Hypothenemus hampei) and their inhibition by two plant amylase inhibitors
150. Digestion of legume starch granules by larvae of Zabrotes subfasciatus (Coleoptera: Bruchidae) and the induction of α-amylases in response to different diets
151. Partial characterization of α-amylase in the salivary glands of Lygus hesperus and L. lineoralis
152. Digestive amylase from the larger grain borre, Prostephnus truncatus Horn
153. The complete amino acid sequence of the bifunctional α-amylase/trypsin inhibitor from seeds of ragi (Indian finger millet, Eleusine coracana Gaertneri.)
154. CATH-A hierarchic classification of protein domain structures
155. SCOP: A structural classification of proteins database for the investigation of sequences and structures
156. A possible function for thaumatin and a TMV-induced protein suggested homology to a maize inhibitor
157. Evolutionary relationships among proteins in the phytohemagglutinin-arcelin-α-amylase inhibitor family of the common bean and its relatives
158. A chimera-like α-amylase inhibitor suggesting the evolution of Phaseolus vulgaris α-amylase inhibitor
159. Regulation of synthesis and transport of secreted proteins in cereal aleurone
160. The inhibition of human salivary alpha-amylase by type II alpha-amylase inhibitor from Triticum aestivum is competitive, slow and tight-binding