Solution structure of the main α-amylase inhibitor from amaranth seeds

European Journal of Biochemistry

Volumn 268, Issue 8, 2001, Pages 2379-2389

  Martins, José C ^a   Enassar, Mohammed ^b   Willem, Rudolph ^a   Wieruzeski, Jean Michel ^c   Lippens, Guy ^c   Wodak, Shoshana J ^b,d  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c INSTITUT PASTEUR DE LILLE   (France)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

amylase inhibitor; Amaranthus hypochondriacus; cis trans isomerization; NMR; X ray

Indexed keywords

AMARANTH; AMYLASE INHIBITOR; CYSTEINE; DISULFIDE; PROLINE;

ARTICLE; CIS ISOMER; CIS TRANS ISOMERISM; CONFORMATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT SEED; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN MOTIF; STRUCTURE ANALYSIS; TRANS ISOMER;

ALPHA-AMYLASE; AMARANTH DYE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DISULFIDES; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDES; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; SEEDS; STEREOISOMERISM; VALINE;

AMARANTHUS CAUDATUS; AMARANTHUS HYPOCHONDRIACUS; INSECTA; MAMMALIA; TENEBRIO MOLITOR;

EID: 0035012409     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02118.x     Document Type: Article

References (48)

1. Natural protein proteinase inhibitors and their interactions with proteinases
2. Proteinase inhibitor gene families: Strategies for transformation to improve plant defense against herbivores
3. Seed storage proteins: The enzyme inhibitors
4. A novel α-amylase inhibitor from amaranth (Amaranthus hypocondriacus) seeds
5. Synthesis and cystine/cysteine-catalyzed oxidative folding of the Amaranth α-amylase inhibitor
6. Crystal structure of yellow meal worm alpha-amylase at 1.64 Å resolution
7. Specific inhibition of insect α-amylases: Yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 Å resolution
8. Solution structure of the major alpha-amylase inhibitor of the crop plant amaranth
9. A gene encoding a hevein-like protein from elderberry (Sambucus nigra) fruits is homologous to PR-4 and class V chitinase genes
10. An improved homonuclear TOCSY Experiment with minimal water saturation
11. Iterative scheme for bilinear rotation operators: Application to spin decoupling
12. Investigation of exchange processes by two dimensional NMR spectroscopy
13. Elucidation of cross-relaxation by two-dimensional NMR spectroscopy
14. Use of flip-back pulse in the homonuclear NOESY experiment
15. A two-dimensional nuclear Overhauser experiment with pure phase in four quadrants
16. Rapid recording of two dimensional NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins
17. Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions
18. 2O solution
19. Correlation of connected transitions by 2D NMR spectroscopy
20. Practical aspects of the E.COSY technique. Measurement of the scalar spin-spin coupling constants in peptides
21. Off-resonance ROESY for the study of dynamic processes
22. Improved versions of off-resonance ROESY
23. A simple solution to decrease angular dispersion in off-resonance experiments
24. 3JHN-α for identification of α-helical secondary structure
25. Protein structures in solution by NMR and distance geometry. The polypeptide fold of the basic pancreatic trypsin inhibitor determined by two different approaches, DISGEO and DISMAN
26. Solution structure of r-elafin, a specific inhibitor of elastase
27. Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system
28. 1H NMR study of the solution structure of Ac-AMP2, a sugar binding antimicrobial protein isolated from Amaranthus caudatus
29. Quality assessment of NMR structures: A statistical survey
30. Theoretical studies of enzymatic reactions: Dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme
31. MOLMOL: A program for display and analysis of macromolecular structures
32. AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
33. PROCHECK: A program to check the stereochemical quality of protein structure
34. Determination of the disulphide bonding pattern in proteins by local and global analysis of nuclear magnetic resonance data. Application to flavoridin
35. Structures of larger proteins in solution: Three- and four-dimensional heteronuclear NMR spectroscopy
36. Exploring the limits of precision and accuracy of protein structures determined by nuclear magnetic resonance spectroscopy
37. Dictionary of protein secondary structure-pattern recognition of hydrogen bondned and geometrical features
38. The disulphide beta-cross: From cystine geometry and clustering to classification of small disulphide-rich protein folds
39. The anatomy and taxonomy of protein structure
40. Molecular recognition between serine proteases and new bioactive microproteins with a knotted structure
41. Protein data bank
42. The Protein Data Bank. A computer-based archival file for macromolecular structures
43. Comparison of the high-resolution structures of the α-amylase inhibitor tendamistat determined by nuclear magnetic resonance in solution and X-ray diffraction in single crystals
44. The solution structure of Eglin-C based on measurements of many nOe's and coupling constants and its comparison with X-ray structures
45. 1H NMR and distance geometry