Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells

Leukemia Research

Volumn 26, Issue 3, 2002, Pages 281-288

  Wang, Jishi ^a,b,d   Chen, Zixing ^a   Xia, Xueming ^a   Lu, Daru ^c   Xue, Jingluen ^c   Ruan, Changgeng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b GUIZHOU MEDICAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Cord blood; Gene co expression; Gene therapy; Hematopoietic stem cell; MDR1 gene; MGMT gene; Retrovirus vector

Indexed keywords

CARMUSTINE; CD34 ANTIGEN; COLCHICINE; COMPLEMENTARY DNA; GLYCOPROTEIN GP 170; GLYCOPROTEIN P; MEMBRANE PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; RETROVIRUS VECTOR; UNCLASSIFIED DRUG; VINCRISTINE;

ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DNA ISOLATION; DNA SEQUENCE; DRUG RESISTANCE; DRUG TOLERANCE; FLOW CYTOMETRY; GENE CONSTRUCT; GENE EXPRESSION; GENE THERAPY; HELPER VIRUS; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; LIVER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TECHNIQUE; UMBILICAL CORD BLOOD; WESTERN BLOTTING;

ANTIGENS, CD; ANTIGENS, CD34; ANTINEOPLASTIC AGENTS; CARMUSTINE; DNA, COMPLEMENTARY; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FETAL BLOOD; FLOW CYTOMETRY; GENES; GENES, MDR; GENETIC VECTORS; HELPER VIRUSES; HEMATOPOIETIC CELL GROWTH FACTORS; HEMATOPOIETIC STEM CELLS; HUMANS; K562 CELLS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; P-GLYCOPROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; VINCRISTINE;

EID: 0036140173     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(01)00111-4     Document Type: Article

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